Search results for "state"

showing 10 items of 9165 documents

Studies towards a directional polychromatic sodium laser guide star

2018

In this work we discuss a mechanism for generation of a coherent source of light from the mesosphere as a new concept of directional laser guide star. In contrast to the near-isotropic spontaneous emission, nonlinear processes in atomic vapors like amplified spontaneous emission can yield highly directional emission in the forward and backward directions. Along with directional emission, excited sodium atoms also radiate at different wavelength creating a polychromatic laser guide star (PLGS). If feasible, a directional PLGS would provide a net gain in the return flux of several orders of magnitude compared to traditional LGS schemes, making possible laser-guided tip/tilt-correction in adap…

0301 basic medicinePhysicsAmplified spontaneous emissionbusiness.industryPhysics::OpticsFlux01 natural sciences010309 optics03 medical and health sciencesWavelength030104 developmental biologyOpticsLaser guide starOrders of magnitude (time)Net gainExcited state0103 physical sciencesSpontaneous emissionbusinessAdaptive Optics Systems VI
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Parametrical Optomechanical Oscillations in PhoXonic Whispering Gallery Mode Resonators

2019

AbstractWe report on the experimental and theoretical analysis of parametrical optomechanical oscillations in hollow spherical phoxonic whispering gallery mode resonators due to radiation pressure. The optically excited acoustic eigenmodes of the phoxonic cavity oscillate regeneratively leading to parametric oscillation instabilities.

0301 basic medicinePhysics::Opticslcsh:MedicineArticlemicrobubbles03 medical and health sciencesResonatorwhispering gallery mode resonators0302 clinical medicineOpticswhispering gallery modeslcsh:SciencePhysicsMultidisciplinarymicrobubble resonatorsbusiness.industryParametric oscillationlcsh:RUNESCO::FÍSICA::Óptica ::Fibras ópticasstimulated brillouin scatteringkerr modulation030104 developmental biologyRadiation pressureOptics and photonics:FÍSICA::Óptica ::Fibras ópticas [UNESCO]Excited stateOther photonicsparametrical optomechanical oscillationslcsh:QWhispering-gallery wavebusiness030217 neurology & neurosurgeryScientific Reports
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Genetic Testing for Melanoma—Where Are We With Moderate-Penetrance Genes?

2016

International audience

0301 basic medicinePreimplantation genetic haplotypingSkin Neoplasmscdkn2aPenetranceDermatologypolicy statement update03 medical and health sciencesCDKN2ApredisposesmedicineHumansGenetic Predisposition to DiseaseGenetic Testingmitf germline mutationGeneMelanomaComputingMilieux_MISCELLANEOUSGenetic testingriskGeneticsmedicine.diagnostic_testbusiness.industryMelanomamedicine.diseaseMicrophthalmia-associated transcription factorcancer susceptibilityPenetrance030104 developmental biologyMutation (genetic algorithm)Mutationbusiness[ SDV.MHEP.DERM ] Life Sciences [q-bio]/Human health and pathology/Dermatologyamerican-society[SDV.MHEP.DERM]Life Sciences [q-bio]/Human health and pathology/Dermatology
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Insights into the inhibited form of the redox-sensitive SufE-like sulfur acceptor CsdE

2017

17 p.-8 fig.

0301 basic medicineProtein ConformationDimerlcsh:MedicineMolecular DynamicsCrystallography X-RayPhysical ChemistryBiochemistryDEAD-box RNA HelicasesMolecular dynamicschemistry.chemical_compoundComputational ChemistryNucleophileBiochemical Simulationslcsh:ScienceMultidisciplinaryCrystallographyChemistryOrganic CompoundsPhysicsEscherichia coli ProteinsCondensed Matter Physics3. Good healthPhysical sciencesChemistryCarbon-Sulfur LyasesBiochemistryCrystal StructureResearch ArticleChemical ElementsProtein subunitChemical physicschemistry.chemical_elementOxidative phosphorylationMolecular Dynamics Simulation03 medical and health sciencesThiolsEscherichia coliSolid State PhysicsProtein Interaction Domains and MotifsChemical BondingOrganic Chemistrylcsh:RChemical CompoundsBiology and Life SciencesComputational BiologyDimers (Chemical physics)Hydrogen BondingCell BiologySulfurAcceptorRedox sensitiveOxidative Stress030104 developmental biologyBiophysicslcsh:QProtein MultimerizationSulfur
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Impact of COVID-19 on global HCV elimination efforts.

2021

Background & Aims COVID-19 has placed significant strain on national healthcare systems at a critical moment in the context of hepatitis elimination. Mathematical models can be used to evaluate the possible impact of programmatic delays on hepatitis disease burden. The objective of this analysis was to evaluate the incremental change in hepatitis C liver-related deaths and liver cancer, following a 3-month, 6-month, or 1-year hiatus in hepatitis elimination program progress. Methods Previously developed models were adapted for 110 countries to include a status quo or “no delay” scenario and a “1-year delay” scenario assuming significant disruption in interventions (screening, diagnosis and …

0301 basic medicinePsychological interventioncoronavirusUMIC upper-middle income countriesGlobal HealthUI uncertainty intervalHIC high income countries0302 clinical medicineCost of IllnessLIC low income countriesMedicineUSA United States of AmericaLetter to the EditorMathematical modellingPWID people who inject drugsLiver DiseaseLiver DiseasesVaccinationmathematical modelingGBD Global Burden of DiseaseHepatitis CSVR sustained virologic responseEuropeHCV hepatitis C virusHepatocellular carcinomaHCVGHSS Global Health Sector StrategyRNA Viral030211 gastroenterology & hepatologyAMR region of the AmericasLiver cancerViral hepatitisHumanCarcinoma HepatocellularCoronavirus disease 2019 (COVID-19)EMR Eastern Mediterranean regionViral hepatitis eliminationviral hepatitisContext (language use)World Health OrganizationArticleWHO World Health OrganizationTime-to-Treatment03 medical and health scienceseliminationEnvironmental healthHumansLMIC lower-middle income countriesDisease EradicationDisease burdenHepatitisHepatologySARS-CoV-2business.industryWPR Western Pacific regionCOVID-19Models Theoreticalmedicine.diseaseCost of Illne030104 developmental biologySpainHCC hepatocellular carcinomabusinessJournal of hepatology
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New Approach of Controlling Cardiac Alternans

2018

The alternans of the cardiac action potential duration is a pathological rhythm. It is considered to be relating to the onset of ventricular fibrillation and sudden cardiac death. It is well known that, the predictive control is among the control methods that use the chaos to stabilize the unstable fixed point. Firstly, we show that alternans (or period-2 orbit) can be suppressed temporally by the predictive control of the periodic state of the system. Secondly, we determine an estimation of the size of a restricted attraction's basin of the unstable equilibrium point representing the unstable regular rhythm stabilized by the control. This result allows the application of predictive control…

0301 basic medicineQuantitative Biology::Tissues and Organs[MATH.MATH-DS]Mathematics [math]/Dynamical Systems [math.DS][ NLIN.NLIN-CD ] Nonlinear Sciences [physics]/Chaotic Dynamics [nlin.CD][ MATH.MATH-DS ] Mathematics [math]/Dynamical Systems [math.DS]Beat (acoustics)[MATH.MATH-DS] Mathematics [math]/Dynamical Systems [math.DS][ SPI.SIGNAL ] Engineering Sciences [physics]/Signal and Image processingFixed point01 natural sciences010305 fluids & plasmasSudden cardiac death03 medical and health sciencesRhythmControl theory0103 physical sciencesmedicineDiscrete Mathematics and CombinatoricsComputingMilieux_MISCELLANEOUSMathematics[SPI.SIGNAL] Engineering Sciences [physics]/Signal and Image processingApplied MathematicsCardiac action potentialmedicine.diseaseModel predictive control030104 developmental biology[NLIN.NLIN-CD] Nonlinear Sciences [physics]/Chaotic Dynamics [nlin.CD]Ventricular fibrillation[NLIN.NLIN-CD]Nonlinear Sciences [physics]/Chaotic Dynamics [nlin.CD][SPI.SIGNAL]Engineering Sciences [physics]/Signal and Image processingStationary state
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Zero-field nuclear magnetic resonance of chemically exchanging systems.

2019

Zero- to ultralow-field (ZULF) nuclear magnetic resonance (NMR) is an emerging tool for precision chemical analysis. In this work, we study dynamic processes and investigate the influence of chemical exchange on ZULF NMR J-spectra. We develop a computational approach that allows quantitative calculation of J-spectra in the presence of chemical exchange and apply it to study aqueous solutions of [15N]ammonium (15N\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$${\mathrm{H}}_4^ +$$\end{document}H4+) as a model syst…

0301 basic medicineReaction kinetics and dynamicsSciencePhysics::Medical PhysicsGeneral Physics and AstronomyModel system02 engineering and technologyGeneral Biochemistry Genetics and Molecular BiologyArticle03 medical and health sciencesNuclear magnetic resonanceZero fieldHyperpolarization (physics)lcsh:ScienceDissolutionQuantitative Biology::Biomolecules3403 Macromolecular and Materials ChemistryMultidisciplinaryAqueous solution34 Chemical SciencesChemical exchangeQ500Diagnostic markersGeneral ChemistryNuclear magnetic resonance spectroscopy021001 nanoscience & nanotechnologyequipment and supplies030104 developmental biologylcsh:Qddc:5000210 nano-technologyhuman activitiesSolution-state NMR51 Physical Sciences
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Extracellular matrix composition defines an ultra-high-risk group of neuroblastoma within the high-risk patient cohort

2016

Background: Although survival for neuroblastoma patients has dramatically improved in recent years, a substantial number of children in the high-risk subgroup still die. Methods: We aimed to define a subgroup of ultra-high-risk patients from within the high-risk cohort. We used advanced morphometric approaches to quantify and characterise blood vessels, reticulin fibre networks, collagen type I bundles, elastic fibres and glycosaminoglycans in 102 high-risk neuroblastomas specimens. The Kaplan-Meier method was used to correlate the analysed elements with survival. Results: The organisation of blood vessels and reticulin fibres in neuroblastic tumours defined an ultra-high-risk patient subgr…

0301 basic medicineRiskCancer ResearchPathologymedicine.medical_specialtyblood vascularisationColorectal cancerKaplan-Meier EstimateRisk AssessmentCollagen Type IExtracellular matrix03 medical and health sciencesProstate cancerNeuroblastomaneuroblastoma0302 clinical medicineNeuroblastomamedicineHumansSurvival rateMolecular Diagnosticscollagen type I fibresbusiness.industryBrain Neoplasmsultra-high-risk neuroblastomaInfantExtracellular matrixelastic fibresmedicine.diseaseElastic TissuePrognosisSurvival RateReticulin030104 developmental biologymedicine.anatomical_structureOncologyglycosaminoglycans030220 oncology & carcinogenesisBlood Vesselsreticulin fibresBone marrowSkin cancerLiver cancerbusiness
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Deciphering function of the pulmonary arterial sphincters in loggerhead sea turtles (Caretta caretta)

2018

To provide new insight to the pathophysiological mechanisms underlying gas emboli (GE) in bycaught loggerhead sea turtles (Caretta caretta), the present study investigated the vasoactive characteristics of the pulmonary and systemic arteries, and the lung parenchyma (LP). Tissues were opportunistically excised from recently dead animals for in vitro studies of vasoactive responses to four different neurotransmitters: acetylcholine (ACh, parasympathetic), serotonin (5HT), epinephrine (Epi, sympathetic) and histamine. The significant amount of smooth muscle in the LP contracted in response to ACh, Epi and histamine. The intrapulmonary and systemic arteries contracted under both parasympatheti…

0301 basic medicineSTEADY-STATEmedicine.medical_specialtyPhysiologyGREEN TURTLECAPE FEAR RIVERCARDIAC SHUNTSAquatic ScienceStress03 medical and health scienceschemistry.chemical_compoundInternal medicinemedicine.arteryParenchymamedicineMolecular BiologyEcology Evolution Behavior and SystematicsDecompression sicknessBLOOD-FLOWbusiness.industryDECOMPRESSION-SICKNESSBlood flowBlood flowDiving physiologyVAGAL CONTROL030104 developmental biologymedicine.anatomical_structurechemistryInsect SciencePulmonary arteryPulmonary blood flowCardiologySphincterPulmonary shuntAnimal Science and ZoologySerotoninmedicine.symptomPHYSIOLOGICAL ADJUSTMENTSbusinessAcetylcholineHistamineGAS-EXCHANGENORTH-CAROLINAmedicine.drugJournal of Experimental Biology
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2020

Worldwide, tons of lignin is produced annually in pulping plants and it is mainly considered as a waste material. Usually lignin is burned to produce energy for the pulping reactors. The production of value-added materials from renewable materials like lignin, has proved to be challenging. In this study, the effects of addition of three different types of lignin in the production of tannin/furanic foams is investigated. The foams were matured, first at 373 K and finally carbonized at 1073 K and the properties of them including mechanical strength, specific surface area and pore development are investigated before and after thermal treatment. According to the results, higher mechanical stren…

0301 basic medicineSolid-state chemistryMultidisciplinaryMaterials scienceCarbonizationCatalyst supportThermal treatmentCatalysis03 medical and health scienceschemistry.chemical_compound030104 developmental biology0302 clinical medicineAdsorptionChemical engineeringchemistrySpecific surface areaLignin030217 neurology & neurosurgeryHeliyon
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