Search results for "static"
showing 10 items of 1528 documents
Fatigue methodology for life predictions for the wheel-rail contact area in large offshore turret bearings
2016
The present report presents a fatigue life prediction method for large roller bearings applied in the turret turn table for large loading buoy units. The contact points between wheel and rail in these bearings are subjected to a multi-axial fluctuating stress situation and both surface wear and fatigue cracking may occur. A methodology based on the Dang Van fatigue criterion is adopted. The criterion is based on an equivalent stress defined as a combination of the fluctuation of the shear stress from its mean value at a critical plane and the associated hydrostatic stress at the given time. The present work is supporting the theoretical model by extensive laboratory testing. Both full scale…
The metrological characterization of the static meters for reactive energy in the presence of harmonic distortion
2007
For the electricity metering for billing purposes in distribution systems, the static meters are substituting the traditional inductive meters. Thus, the evaluation of the performances of such equipments is required, also in the presence of disturbances affecting the power systems. With respect to this, this paper analyzes the main aspects related to the metrological characterization of the static meters for reactive energy in the presence of harmonic distortion. Particular attention is given to the reference standard meters, that are not considered by the actual in-force Standards. The analysis is supported by several experimental tests.
Static meters for the reactive energy in the presence of harmonics: an experimental metrological characterization
2009
Electricity metering plays a crucial role for all the commercial transactions on the energy market. Thus, an accurate evaluation of the performance of the electricity metering equipment is required not only in the reference operating conditions but also in the presence of disturbances affecting the power systems. As regards this matter, this paper analyzes the main aspects related to the metrological characterization of the static meters for the reactive energy in the presence of harmonic distortion. Attention is focused not only to the meters covered by the current standards but also to the meters of better accuracy and to the reference standard meters. The analysis is supported by several…
Influence Of Lateral Load Distributions On Pushover Analysis Effectiveness
2008
The effectiveness of two simple load distributions for pushover analysis recently proposed by the authors is investigated through a comparative study, involving static and dynamic analyses of seismic response of eccentrically braced frames. It is shown that in the upper floors only multimodal pushover procedures provide results close to the dynamic profile, while the proposed load patterns are always conservative in the lower floors. They over-estimate the seismic response less than the uniform distribution, representing a reliable alternative to the uniform or more sophisticated adaptive procedures proposed by seismic codes. © 2008 American Institute of Physics.
A New Quasi-Static Cylindrical Roller Bearing Model to Accurately Consider Non-Hertzian Contact Pressure in Time Domain Simulations
2012
The accuracy of the fatigue life calculations in rolling bearing simulations is highly dependent on the precision of the roller-raceway contact simulations. Several different methods exist to simulate these pressure distributions and in time domain bearing simulations, where many contacts need evaluation, the simple and time efficient methods are more popular, yielding erroneous life estimates. This paper presents a new six degree of freedom frictionless quasi-static time domain cylindrical roller bearing model that uses high precision elastic half-space theory to simulate the contact pressures. The potentially higher computational demand using the advanced contact calculations is addressed…
Modeling and simulation of a VCM micromotor and its potential applications
2013
This paper presents the modeling and simulation of a VCM electrostatic micromotor with a new FEM analysis and implementation method, in order to determine the electrical parameters of the model and the generated electrostatic torque. Both the modeling and the simulation have been achieved using several software programs. In particular, the geometric model created with AUTOCAD has been imported to the FEMM program for the finite-element-method analysis. Then, with the LUA and MATLAB simulation programs, the parameters of the model and the related electrostatic torque have been calculated. The results obtained from this work have been compared with those reported in other scientific papers, s…
The first European interdisciplinary ewing sarcoma research summit.
2012
This is an open-access article distributed under the terms of the Creative Commons Attribution Non Commercial License.-- et al.
Multicenter study of the eValuation of Eribulin (E) use in Sicily in metastatic breast cancer (MBC): A Prospective RegistrY (VESPRY trial)
2015
e12565 Background: Eribulin Mesylate is a non taxane microtubule dynamics inhibitor, approved for heavily-pretreated MBC patients (pts). Methods: This is a multicenter, prospective, single arm study for E-treatment of third line in pretreated MBC pts, conducted in 14 oncology centers in Sicily. All pts had received two previous chemotherapy regimens for MBC. Pts received E at 1.23 mg/m2 on days 1,8 every 3 weeks until progression. Primary Endpoints: overall response rate (ORR) according to the site of metastases and safety. Secondary objectives: Progression-free survival (PFS) and ORR according to different subtypes. PFS curve was estimated using the Kaplan-Meier method. Multivariable logi…
Eribulin Mesylate for the Treatment of Metastatic Hormone-refractory and Triple-negative Breast Cancer: A Multi-institutional Real-world Report on Ef…
2021
Objective Eribulin mesylate (EM) is a fully synthetic macrocyclic ketone analogue of the marine natural product halichondrin. EM has been reported to be active in metastatic breast cancer. In this paper, we report efficacy and safety of data of EM in a retrospective, real-world series of patients with poor prognosis, hormone-refractory, or triple-negative metastatic breast cancer. Materials and methods The analysis was carried out at 4 interrelated oncology centers. EM was delivered at the dose of 1.4 mg/m2 in 100 mL of normal saline over 2 to 5 minutes on days 1 and 8 every 21 days. EM was continued until disease progression or unacceptable toxicity. Side effects were reported every cycle …
New pegylated polyaspartamide-based polyplexes as gene delivery vectors
2010
Aims: To synthesize novel polyhydroxyethylaspartamide (PHEA) copolymers containing spermine (Spm) and polyethylene glycol (PEG) moieties in high yields, with the expectation that this material would show stealth properties and the ability to complex DNA by electrostatic interactions. Materials & methods: PHEA–PEG–Spm copolymer was prepared with a two-step reaction. Chemical, physicochemical and biological characterizations of PHEA–PEG–Spm copolymers and their obtained polyplexes with pDNA were performed. Results: The introduction of spermine in PHEA structure allows to obtain a copolymer bearing in the side chains polyamine moieties capable to interact with DNA. On the other hand, the …