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showing 10 items of 1632 documents

Female obesity increases the risk of miscarriage of euploid embryos.

2020

Objective To determine whether female body mass index (BMI) is associated with an increased risk of miscarriage after euploid embryo transfer. Design A retrospective, observational, multicenter cohort study. Setting University-affiliated in vitro fertilization center. Patient(s) In this study, 3,480 cycles of in vitro fertilization with preimplantation genetic testing for aneuploidy (PGT-A) in the blastocyst stage and euploid embryo transfer were divided into four groups according to patient BMI. Intervention(s) In vitro fertilization with PGT-A. Main Outcome Measure(s) The primary outcome was the miscarriage rate, which included both biochemical and clinical miscarriages. Secondary outcome…

0301 basic medicinemedicine.medical_specialtyPregnancy RateAneuploidyFertilization in VitroRisk AssessmentMiscarriageBody Mass IndexObesity Maternal03 medical and health sciences0302 clinical medicinePregnancyRisk FactorsMedicineHumansEmbryo ImplantationGenetic TestingPreimplantation DiagnosisRetrospective StudiesPregnancy030219 obstetrics & reproductive medicinebusiness.industryObstetricsObstetrics and Gynecologymedicine.diseaseAneuploidyEmbryo TransferEmbryo transferGestational Weight GainAbortion Spontaneous030104 developmental biologyBlastocystTreatment OutcomeReproductive MedicineSpainInfertilityembryonic structuresFemaleUnderweightmedicine.symptombusinessLive birthBody mass indexLive BirthCohort studyFertility and sterility
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Comparison of total antioxidant capacity of saliva in women with gestational diabetes mellitus and non-diabetic pregnant women

2017

Background Pregnancy is considered a stressful event, results in higher levels of oxidative stress and considerable changes in physiological and metabolic functions such as gestational diabetes mellitus (GDM). Due to the cumulative effect of antioxidants and considering the controversies in this area, this study was undertaken to investigate the total antioxidant capacity (TAC) of saliva in pregnant women whit gestational diabetes in comparison to non-diabetic pregnant women. Material and methods In this cross-sectional study (2015-16), a total of 31 women with a diagnosis of GDM and 59 non-diabetic pregnant women were included in the diabetic and control groups, respectively. Salivary samp…

0301 basic medicinemedicine.medical_specialtySalivaPhysiologymedicine.disease_cause03 medical and health sciences0302 clinical medicineInternal medicineDiabetes mellitusMedicineGeneral DentistryCumulative effectPregnancyOral Medicine and Pathologybusiness.industryResearchmedicine.disease:CIENCIAS MÉDICAS [UNESCO]Gestational diabetesAntioxidant capacity030104 developmental biologyEndocrinology030220 oncology & carcinogenesisUNESCO::CIENCIAS MÉDICASbusinessOxidative stressNon diabetic
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Role of T-Cell Polarization and Inflammation and Their Modulation by n-3 Fatty Acids in Gestational Diabetes and Macrosomia.

2015

Th (T helper) cells are differentiated into either Th1 or Th2 phenotype. It is generally considered that Th1 phenotype is proinflammatory, whereas Th2 phenotype exerts anti-inflammatory or protective effects. Gestational diabetes mellitus (GDM) has been associated with a decreased Th1 phenotype, whereas macrosomia is marked with high expression of Th1 cytokines. Besides, these two pathological situations are marked with high concentrations of inflammatory mediators like tumor necrosis factor-α(TNF-α) and interleukin-6 (IL-6), known to play a pivotal role in insulin resistance. Dietary n-3 polyunsaturated fatty acids (n-3 PUFAs) may exert a beneficial effect by shifting Th1/Th2 balance to a …

0301 basic medicinemedicine.medical_specialty[ SDV.AEN ] Life Sciences [q-bio]/Food and NutritionEndocrinology Diabetes and MetabolismAcyl-chainLymphocyte SubpopulationsInflammationReview ArticleBiologyProinflammatory cytokinePeripheral-Blood03 medical and health sciencesInsulin resistanceInternal medicinemedicineMultiple-sclerosislcsh:RC620-627chemistry.chemical_classificationMonocyte recruitmentNutrition and DieteticsPlasma leptinUnique populationInsulin-resistancemedicine.diseasePhenotypePathophysiologyGestational diabetesDocosahexaenoic acidlcsh:Nutritional diseases. Deficiency diseasesC-Reactive Protein030104 developmental biologyEndocrinologychemistryTumor necrosis factor alphamedicine.symptomFood SciencePolyunsaturated fatty acidJournal of nutrition and metabolism
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Prevention of Teratogenesis in Pregnancies of Obese Rats by Vitamin E Supplementation

2021

Congenital malformations are a common adverse outcome in pregnancies complicated by pregestational obesity, although the underlying mechanisms are still unrevealed. Our aim was to study the effect of oxidative stress in obesity-induced teratogenesis. Wistar rats were fed a high-fat diet for 13 weeks, with (OE group) or without (O group) vitamin E supplementation. Then, rats were mated and sacrificed at day 11.5 of gestation. Embryos from O dams presented a 25.9 ± 3.5% rate of malformations (vs. 8.7 ± 3.4% in C rats), which was reduced in the OE group (11.5 ± 2.3%). Pregestational obesity induced hepatic protein and DNA oxidation and a decline in antioxidant enzymes. Importantly, glutathione…

0301 basic medicinemedicine.medical_specialtyobesityAntioxidantPhysiologymedicine.medical_treatmentEmbryo malformationClinical Biochemistry030209 endocrinology & metabolismRM1-950vitamin Emedicine.disease_causeBiochemistryArticle03 medical and health scienceschemistry.chemical_compound0302 clinical medicineInternal medicinemedicineoxidative stressVitamin EButhionine sulfoximineObesityglutathioneMolecular Biologyembryo malformation; teratogenesis; oxidative stress; glutathione; vitamin E; obesitybusiness.industryVitamin EEmbryoCell BiologyGlutathioneDNA oxidationGlutathioneembryo malformation030104 developmental biologyEndocrinologychemistryOxidative stressGestationteratogenesisTeratogenesisTherapeutics. PharmacologybusinessOxidative stress
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Influence of fetal glutathione S-transferase copy number variants on adverse reproductive outcomes

2012

A nested case-control association study was designed to investigate the influence of maternal and fetal copy number variants (CNVs) on reproductive outcomes. Genotypes of ten CNVs encompassing GST and CYP genes were assessed. Significant associations were only found for child CNV genotypes. In particular, the child GSTM1 insertion allele was associated with prematurity protection (odds ratio, 95% CI: 0.67, 0.51-0.89; P < 0.01), whereas the child GSTT2B insertion allele was associated with an increased risk of being small for gestational age (odds ratio, 95% CI: 1.33, 1.07-1.67; P = 0.01). The study highlights the role of the fetal genome in prenatal development and also the need to analyse …

0303 health sciencesFetus030219 obstetrics & reproductive medicinebiologybusiness.industryObstetrics and GynecologyOdds ratioBioinformaticsmedicine.diseasePrenatal development03 medical and health sciences0302 clinical medicineGlutathione S-transferasemental disordersGenotypebiology.proteinMedicineSmall for gestational ageCopy-number variationAllelebusiness030304 developmental biologyBJOG: An International Journal of Obstetrics &amp; Gynaecology
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Comment lutter contre la perte de goût en gériatrie ?

2021

International audience

0303 health sciencesNutrition and Dietetics[SDV.MHEP.GEG] Life Sciences [q-bio]/Human health and pathology/Geriatry and gerontology030309 nutrition & dieteticsodor[SDV.MHEP.GEG]Life Sciences [q-bio]/Human health and pathology/Geriatry and gerontologyaging030209 endocrinology & metabolismgustationelderlyolder peopletaste03 medical and health sciences[SDV.AEN] Life Sciences [q-bio]/Food and Nutritionaged0302 clinical medicineageing[SDV.AEN]Life Sciences [q-bio]/Food and NutritionComputingMilieux_MISCELLANEOUSolfaction
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Evaluation of geomorphometric characteristics and soil properties after a wildfire using Sentinel-2 MSI imagery for future fire-safe forest

2021

Abstract Understanding spatiotemporal geomorphological and pedological changes as a consequence of wildfires can allow stakeholders, land planners, and policymakers to design efficient fire safety-based afforestation and restoration programs of forest lands. The use of remote sensing techniques is a key tool to achieve this goal. The suitable combination of Sentinel-2 MSI data for mapping of different spectral indices related to burn severity and their relationship with other morphometric and soil properties can contribute to a better understanding of the impact of fire, and this is relevant in regions where is still scarce fire-related research such as Turkey. In this investigation, the us…

040101 forestryIndex (economics)Normalized burn ratioGeneral Physics and Astronomy020101 civil engineeringTerrain04 agricultural and veterinary sciences02 engineering and technologyGeneral ChemistryBuilding and ConstructionNormalized Difference Vegetation Index0201 civil engineering0401 agriculture forestry and fisheriesAfforestationEnvironmental scienceGeneral Materials ScienceSoil propertiesPhysical geographySafety Risk Reliability and QualityRelevant informationStream powerFire Safety Journal
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Cell state prediction through distributed estimation of transmit power

2019

Determining the state of each cell, for instance, cell outages, in a densely deployed cellular network is a difficult problem. Several prior studies have used minimization of drive test (MDT) reports to detect cell outages. In this paper, we propose a two step process. First, using the MDT reports, we estimate the serving base station’s transmit power for each user. Second, we learn summary statistics of estimated transmit power for various networks states and use these to classify the network state on test data. Our approach is able to achieve an accuracy of 96% on an NS-3 simulation dataset. Decision tree, random forest and SVM classifiers were able to achieve a classification accuracy of…

050101 languages & linguisticsComputer science05 social sciencesProcess (computing)Decision tree5G-tekniikka02 engineering and technologymatkaviestinverkotTransmitter power outputcomputer.software_genreRandom forestcell outage detectionSupport vector machineBase stationmachine learningkoneoppiminen0202 electrical engineering electronic engineering information engineeringCellular network5G cellular networks020201 artificial intelligence & image processing0501 psychology and cognitive sciencesData miningcomputerTest data
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Poplar biomass production at phytomanagement sites is significantly enhanced by mycorrhizal inoculation

2017

Abstract Afforestation of trace element (TE)-contaminated soil, notably with fast growing trees producing large biomass has been demonstrated to be an attractive option for their bioremediation. Mycorrhizal fungi can form symbiotic associations with plants, contributing to TE tolerance and participating actively in bioremediation processes. We studied the effects of mycorrhizal inoculation on the growth of two poplar clones (Skado and I214), to large-scale. Two TE-contaminated sites of ca . 1 ha (Pierrelaye and Fresnes-sur-Escaut, France) were planted with 2200 trees, and were either inoculated with a mixed commercial inoculum or not-inoculated and allometric parameters were determined afte…

2. Zero hunger0106 biological sciences[SDV.EE]Life Sciences [q-bio]/Ecology environmentBioaugmentationInoculationfood and beveragesBiomassPlant Science15. Life on land010501 environmental sciencesContaminationBiology01 natural sciencesSoil contamination[ SDV.EE ] Life Sciences [q-bio]/Ecology environmentBioremediationSoil structureAgronomyAfforestationAgronomy and Crop ScienceEcology Evolution Behavior and SystematicsComputingMilieux_MISCELLANEOUS010606 plant biology & botany0105 earth and related environmental sciences
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Le goût : physiologie, rôles et dysfonctionnements

2013

Article de vulgarisation; National audience; The sense of taste involves multimodal sensory activation to detect and identify many flavors. Today, five primary tastes have been identified (sweet, salt, sour, bitter and umami). These are often combined to form complex tastes. The physiology of gustatory pathways is complex. The activation of gustatory receptors located in the mouth leads to an ascendant pathway through the neurons of the solitary nucleus in the brainstem and the neurons located in the thalamus. After the thalamus, the gustative signal modulates the ipsilateral primary taste cortex and then the secondary taste area. The secondary taste cortex, which combines representations o…

2. Zero hunger0303 health sciencesmédicamentNutrition and Dieteticsfood intake030309 nutrition & dieteticsEndocrinology Diabetes and Metabolismdrugrécepteur sensorielgustationprise alimentairesensory receptortaste03 medical and health sciences0302 clinical medicine030220 oncology & carcinogenesisInternal Medicinepathology[SDV.AEN]Life Sciences [q-bio]/Food and Nutrition
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