Search results for "stigmate"

showing 3 items of 3 documents

Coordination of the biliverdin D-ring in bacteriophytochromes.

2018

Phytochrome proteins translate light into biochemical signals in plants, fungi and microorganisms. Light cues are absorbed by a bilin chromophore, leading to an isomerization and a rotation of the D-ring. This relays the signal to the protein matrix. A set of amino acids, which is conserved across the phytochrome superfamily, holds the chromophore in the binding pocket. However, the functional role of many of these amino acids is not yet understood. Here, we investigate the hydrogen bonding network which surrounds the D-ring of the chromophore in the resting (Pr) state. We use UV/vis spectroscopy, infrared absorption spectroscopy and X-ray crystallography to compare the photosensory domains…

0301 basic medicineModels MolecularStereochemistryProtein ConformationProtein Data Bank (RCSB PDB)General Physics and Astronomyphytochrome proteinsbakteerit03 medical and health scienceschemistry.chemical_compoundProtein structureBacterial ProteinsProteobacteriabiochemical signalsDeinococcusPhysical and Theoretical ChemistryStigmatella aurantiacaBiliverdinBinding SitesbiologyPhytochromeBiliverdineta1182Deinococcus radioduransHydrogen BondingChromophorebiology.organism_classificationPhotochemical ProcessesD-ring030104 developmental biologychemistryproteiinitvalokemiaDeinococcusPhytochromeProtein BindingPhysical chemistry chemical physics : PCCP
researchProduct

Structural basis for light control of cell development revealed by crystal structures of a myxobacterial phytochrome

2018

Phytochromes are red-light photoreceptors that were first characterized in plants, with homologs in photosynthetic and non-photosynthetic bacteria known as bacteriophytochromes (BphPs). Upon absorption of light, BphPs interconvert between two states denoted Pr and Pfr with distinct absorption spectra in the red and far-red. They have recently been engineered as enzymatic photoswitches for fluorescent-marker applications in non-invasive tissue imaging of mammals. This article presents cryo- and room-temperature crystal structures of the unusual phytochrome from the non-photosynthetic myxobacterium Stigmatella aurantiaca (SaBphP1) and reveals its role in the fruiting-body formation of this ph…

MODULE0301 basic medicinePHOTOACTIVE YELLOW PROTEINSIGNALING MECHANISMabsorption spectraMutantfotobiologiaphytochromesBiochemistryyhteyttäminenbakteeritSTIGMATELLA-AURANTIACA03 medical and health sciencesFRUITING BODY FORMATIONGeneral Materials ScienceMolecular replacementStigmatella aurantiacalcsh:ScienceUNUSUAL BACTERIOPHYTOCHROMEPHOTOCONVERSIONHistidine030102 biochemistry & molecular biologybiologyPhytochromeChemistryCRYSTALLOGRAPHYta1182photosynthetic bacteriaphotoreceptorsGeneral ChemistryChromophoreCondensed Matter Physicsbiology.organism_classification030104 developmental biologyCHROMOPHORE-BINDING DOMAINBiophysicsmyxobacterialcsh:Q3111 BiomedicinePhotosynthetic bacteriaproteiinitMOLECULAR REPLACEMENTBinding domainIUCrJ
researchProduct

De la conscience fière au stigmate social : le virilisme ouvrier à l’épreuve des années 1968

2014

La masculinité ouvrière, en tant que caractère(s) du masculin, ressortit, on le sait, au virilisme : l’exhibition du corps fort liée à la dureté du travail, une manière d’exacerbation de la masculinité, relèvent de la culture ouvrière. Dès lors, le virilisme désignerait en première approche une forme d’ostentation de la virilité, qui en vient à faire système : non pas seulement l’exaltation de vertus masculines supposées – force, courage, endurance, etc., mais aussi réflexion, sagacité, etc. ...

hommesidentité sexuelle[ SHS.HIST ] Humanities and Social Sciences/HistoryHBconscienceJFSJsocialmasculinitévirilité16. Peace & justiceSOC032000histoire du corpsfièreArchaeology[SHS.HIST] Humanities and Social Sciences/HistoryhistoireHIS000000virilisme ouvrierannées 1968stigmateSociology & Anthropology[SHS.HIST]Humanities and Social Sciences/HistoryComputingMilieux_MISCELLANEOUS
researchProduct