Search results for "stil"
showing 10 items of 1452 documents
Curcumin and trans-resveratrol exert cell cycle-dependent radioprotective or radiosensitizing effects as elucidated by the PCC and G2-assay
2013
Curcumin and trans-resveratrol are well-known antioxidant polyphenols with radiomodulatory properties, radioprotecting non-cancerous cells while radiosensitizing tumor cells. This dual action may be the result of their radical scavenging properties and their effects on cell-cycle checkpoints that are activated in response to radiation-induced chromosomal damage. It could be also caused by their effect on regulatory pathways with impact on detoxification enzymes, the up-regulation of endogenous protective systems, and cell-cycle-dependent processes of DNA damage. This work aims to elucidate the mechanisms underlying the dual action of these polyphenols and investigates under which conditions…
Prevenció de la malaltia d'Alzheimer en etapes primerenques i mitjanes de la vida
2015
La malaltia d'Alzheimer és la causa més freqüent de demència a l'edat adulta. A més, la seua incidència s'incrementa fortament amb l'edat i, és per això, que la seua prevalença està augmentant en tot el món degut a l'augment a l'expectativa de vida. Clínicament es caracteritza per un dèficit cognitiu progressiu i irreversible i alteracions de la conducta que afecten a la memòria i altres dominis cognitius, a la capacitat d'aprenentatge, activitats de la vida diària i, en últim terme, a la qualitat de vida. Donat que el tractament farmacèutic disponible actualment solament pot millorar moderadament els símptomes, la modificació de factors de risc a etapes primerenques i mitjanes de la vida é…
Extreme Methylation Values of Imprinted Genes in Human Abortions and Stillbirths
2010
Imprinted genes play an important role in fetal and placental development. Using quantitative bisulfite pyrosequencing assays, we determined the DNA methylation levels at two paternally methylated (H19 and MEG3) and four maternally methylated (LIT1, NESP55, PEG3, and SNRPN) imprinted regions in fetal muscle samples from abortions and stillbirths. Two of 55 (4%) spontaneous abortions and 10 of 57 (18%) stillbirths displayed hypermethylation in multiple genes. Interestingly, none of 34 induced abortions had extreme methylation values in multiple genes. All but two abortions/stillbirths with multiple methylation abnormalities were male, indicating that the male embryo may be more susceptible t…
Sobre la presencia actual de "Atropa baetica" Willk. (Solanaceae) en la Alta Alcarria (Utande, Guadalajara)
2016
Se da noticia del hallazgo y presencia actual de "Atropa baetica" Willk. (Solanaceae) en una localidad de la Alta Alcarria, municipio de Utande (provincia de Guadalajara). Se indica la cuadrícula U.T.M. de 1×1 km donde se encuentra. Se presentan datos ecológicos y fitogeográficos básicos sobre su emplazamiento, algunos datos vegetativos descriptivos de los dos rodales o conjuntos de tallos encontrados y comentarios sobre posibles amenazas de la escueta población. Finalmente, se comenta la relación de esta nueva cita con referencias antiguas publicadas en la bibliografía.
Acogimiento en familia extensa: perfil psicosocial de las familias y de los menores acogidos
2021
[EN] Extended family foster care family is the most frequent protective measure for minors in Spain. The objectives of the present study are to analyze the family profile according to different dimensions, knowing the state of psychosocial health care of minors in foster care and study the relationship between family and minor variables. The sample consisted of 101 families and 121 minors between 6 and 17 years old (M = 10.07; DT = 3.92), living in the province of Valencia. The evaluation was carried out through individual interviews with every family. Results show good functionality of families taking into account the family climate, the level of stress, the educational styles and the supp…
Efficacy of an Internet-Based Intervention to Promote a Healthy Lifestyle on the Reproductive Parameters of Overweight and Obese Women: Study Protoco…
2020
Este artículo se encuentra disponible en la siguiente URL: https://www.mdpi.com/1660-4601/17/22/8312 En este artículo también participan: Valentina Lucia La Rosa y Rosa M. Baños. Este artículo pertenece al número especial "Developmental and emotional aspects of pregnancy, childbirth, and parenting: current and future perspectives". Background: Infertility is estimated to affect 15% of couples of reproductive age. Weight management problems (being obese or overweight) are among the problems that produce infertility, both in women seeking spontaneous pregnancy and in those undergoing assisted reproduction techniques. Over the last few decades, the prevalence of obesity has increased alarmingl…
Lifestyles and risk factors associated with adherence to the Mediterranean diet: a baseline assessment of the PREDIMED trial
2013
Background: The traditional Mediterranean dietary pattern (MedDiet) is associated with longevity and low rates of cardiovascular disease (CVD). However, there is little information on who is more likely to follow this food pattern. Aim: To evaluate how different factors are associated with lower MedDiet adherence in older Spanish subjects. Methods: We included 7305 participants (men aged 55-80 y, women 60-80 y) at high-risk of CVD recruited into the PREDIMED trial (ISRCTN35739639). Socioeconomic, anthropometric, lifestyle characteristics and CVD risk factors were recorded. A validated 14-item questionnaire was used to evaluate MedDiet adherence at baseline. Multivariate models were used to …
Antioxidants in Translational Medicine.
2015
This Open Access article is distributed under the terms of the Creative Commons Attribution Noncommercial License.-- et al.
Production of the Sicilian distillate “ Spiritu re fascitrari ” from honey by-products: An interesting source of yeast diversity
2017
The “Spiritu re fascitrari” (SRF) is a typical Sicilian distillate obtained from the by-products of traditional process of honey production. Although some alcoholic fermentation of honey based products have been described, the present research represents the first investigation on the yeast ecology and the physico-chemical characteristics of honey by-products subjected to an alcoholic fermentation followed by distillation. All samples collected during manufacturing process were analysed for the count of total, osmophilic and osmotolerant yeasts. The honeycombs and equipment surfaces showed the presence of yeasts that was 1.7 and 1.1 Log (CFU/mL), respectively. After enrichment, yeast popula…
Vizuāli stilistisko aspektu efektivitāte plakātu dizainā
2019
Neskatoties uz mūsdienu tehnoloģiju neskaitāmajām komunikāciju formām, plakāti vēlaizvien ir aktuāls vizuālās komunikācijas līdzeklis, kā arī tiem vēlaizvien ir stabila loma reklāmas jomā. Plakāta spēja adaptēties ir satriecoša, un tas ir rādītājs tam, ka plakāti vēl kādu laiku uzkavēsies sabiedrības vizuālajā telpā. Plakāta izmantojamības popularitāte raisa dažas problēmas. Tie ir bieži sastopami un līdz ar to tas ir profesionāls izaicinājums katram māksliniekam un dizainerim izveidot efektīvu plakātu. Būtu vērtīgi izpētīt, kāds ir efektīfs plakāts un ar kādām metodēm tiek panākta plakāta efektivitāte. Darba mērķis ir izveidot efektīvu plakātu sēriju sociālās reklāmas kampaņai “#velodrošs”…