Search results for "stratification"
showing 10 items of 210 documents
Intergenerational support as a reaction to socio-economic crisis: alteration of solidarity within precarious Romanian households
2017
ABSTRACTThis paper addresses the tensions arising from the intersection of norms and practices of support in situations in which intergenerational support is the main household strategy for coping with precariousness in Romania. This paper describes competing meanings of solidarity and reveals gendered experiences of ambiguity with respect to the sustainability of help exchanges within the context of economic vulnerability. Romania displays high public acceptance of intergenerational support, while the country’s deficient social welfare system prompts families to intensify their help exchanges. Findings based on in-depth interviews suggest that private arrangements are compounded by unbalan…
Rationale, design and methods of CTCA-PRORECAD (Computed Tomography Coronary Angiography Prognostic Registry for Coronary Artery Disease): a multicen…
2013
PURPOSE: This study was done to assess the prognostic value of computed tomography coronary angiography (CTCA) in a large multicentre population of patients with suspected coronary artery disease (CAD) and, in particular, its incremental value compared with traditional methods for risk stratification. MATERIALS AND METHODS: This is a retrospective observational study that began in January 2003 conducted on patients with suspected CAD assessed with CTCA on the basis of symptoms (chest pain, dyspnoea) and/or abnormal or equivocal stress test and/or a high cardiovascular risk profile. The participating centres will provide data obtained with CTCA performed with 16-slice or higher equipment. Ex…
The relationship between health-related quality of life and melancholic depressive symptoms is modified by brain insulin receptor gene network
2021
AbstractTo investigate whether expression-based polygenic risk scores for the insulin receptor gene network (ePRS-IRs) modifiy the association between type of depressive symptoms and health-related quality of life (HRQoL). This cross-sectional study includes 1558 individuals from the Helsinki Birth Cohort Study. Between 2001 and 2004, the Short Form-36 questionnaire was employed to assess mental and physical components of HRQoL and Beck Depression Inventory (BDI) to assess depressive symptoms. Depressive symptoms were categorized into minimal (BDI < 10), non-melancholic and melancholic types of depression. The ePRS-IRs were calculated for the hippocampal (hePRS-IR) and the mesocorticolim…
CH4 oxidation in a boreal lake during the development of hypolimnetic hypoxia
2020
AbstractFreshwater ecosystems represent a significant natural source of methane (CH4). CH4 produced through anaerobic decomposition of organic matter (OM) in lake sediment and water column can be either oxidized to carbon dioxide (CO2) by methanotrophic microbes or emitted to the atmosphere. While the role of CH4 oxidation as a CH4 sink is widely accepted, neither the magnitude nor the drivers behind CH4 oxidation are well constrained. In this study, we aimed to gain more specific insight into CH4 oxidation in the water column of a seasonally stratified, typical boreal lake, particularly under hypoxic conditions. We used 13CH4 incubations to determine the active CH4 oxidation sites and the …
Seasonal variability of radiation tide in Gulf of Riga
2020
Diurnal oscillations of water level in Gulf of Riga are considered. It was found that there is distinct daily pattern of diurnal oscillations in certain seasons. The role of sea breeze, gravitational tides and atmospheric pressure gradient are analysed. The interference of the first two effects provide the dominant role in diurnal oscillations. The effect of gravitational tides is described both with sole tidal forcing and also in real case with atmospheric forcing and stratification. The yearly variation of the declination of the Sun and stratification leads to seasonal intensification of gravitational tides in Gulf of Riga. Correlation between gravitational tide of the Sun with its radiat…
Context matters-consensus molecular subtypes of colorectal cancer as biomarkers for clinical trials
2019
Abstract The Colorectal Cancer Subtyping Consortium identified four gene expression consensus molecular subtypes, CMS1 (immune), CMS2 (canonical), CMS3 (metabolic), and CMS4 (mesenchymal), using multiple microarray or RNA-sequencing datasets of primary tumor samples mainly from early stage colon cancer patients. Consequently, rectal tumors and stage IV tumors (possibly reflective of more aggressive disease) were underrepresented, and no chemo- and/or radiotherapy pretreated samples or metastatic lesions were included. In view of their possible effect on gene expression and consequently subtype classification, sample source and treatments received by the patients before collection must be ca…
Methyl-CpG-binding domain sequencing reveals a prognostic methylation signature in neuroblastoma
2016
Accurate assessment of neuroblastoma outcome prediction remains challenging. Therefore, this study aims at establishing novel prognostic tumor DNA methylation biomarkers. In total, 396 low- and high-risk primary tumors were analyzed, of which 87 were profiled using methyl-CpG-binding domain (MBD) sequencing for differential methylation analysis between prognostic patient groups. Subsequently, methylation-specific PCR (MSP) assays were developed for 78 top-ranking differentially methylated regions and tested on two independent cohorts of 132 and 177 samples, respectively. Further, a new statistical framework was used to identify a robust set of MSP assays of which the methylation score (i.e.…
Romanian Households Dealing with Precariousness: A life-course approach
2016
This paper addresses the main pathways through which households avoid slipping into poverty in Romania by employing a life-course approach. Recent researches on social stratification found that in every country we can delineate a particular social layer composed of households living just above the poverty threshold, whose members struggle to reach a more secure prosperity while facing constant threats of downward mobility. Drawing on recent precarious prosperity research, and based on in-depth interviews carried out in 2013 with 25 households situated in between poverty and prosperity from a Romanian city (Cluj-Napoca), we use a life-course approach in order to account for the main routes i…
Inequalities in educational opportunities in France: educational expansion, democratization or shifting barriers?
2000
International audience; This paper is concerned with inequalities in educational opportunities in France and presents data collected from cohorts born between 1919 and 1973, a period characterized by educational expansion. Data from large-scale representative French surveys were compiled in such a way as to make accurate historical and international comparisons possible. The paper argues that there has been a shift in social inequalities, from entry into collège (lower secondary school) to entry into lycée (upper secondary school leading to the baccalauréat). Finally, policy implications have been drawn from international comparisons of data on the reduction of social inequality. Cet articl…
Young people not in employment, education or training (NEET): the role of basic competencies
2021
A top priority for public policies at both national and European levels, young people who are not in employment, education or training (NEET) face a risk of exclusion that varies in intensity from country to country. While education level plays a central role in these situations, viewing them through the lens of basic competencies sharpens the focus. After all, the international data show that the same level of qualification does not guarantee the same level of competencies everywhere. How can these differences be explained? To what extent do these basic competencies protect young people from becoming not in employment, education or training regardless of their level of qualification?