Search results for "string"
showing 10 items of 381 documents
Binding site of different tannins on a human salivary proline-rich protein evidenced by dissociative photoionization tandem mass spectrometry
2015
Abstract The sensation of astringency is thought to originate from the interaction occurring between tannins and the salivary proline-rich proteins (PRPs). Astringency perception can be modified by the structure of tannins. Herein, we study the interactions occurring between the human salivary PRP, IB5, and three model tannins with different structure, epigallocatechin gallate and the procyanidin dimers B2 and B2 3′ O -gallate, using the coupling of mass spectrometry and VUV-synchrotron radiation. The results obtained indicate that the structure of tannins, in particular the degree of polymerization and the galloylation, does not modify the binding site on IB5 involved in the interaction.
Locality-Sensitive Hashing for Massive String-Based Ontology Matching
2014
This paper reports initial research results related to the use of locality-sensitive hashing (LSH) for string-based matching of big ontologies. Two ways of transforming the matching problem into a LSH problem are proposed and experimental results are reported. The performed experiments show that using LSH for ontology matching could lead to a very fast matching process. The quality of the alignment achieved in these experiments is comparable to state-of-the-art matchers, but much faster. Further research is needed to find out whether the use of different metrics or specific hardware would improve the results. peerReviewed
Effect of aluminum chloride hemostatic agent on microleakage of class V composite resin restorations bonded with all-in-one adhesive
2012
Objectives: Since hemostatic agents can induce changes on enamel and dentin surfaces and influence composite resin adhesion, the aim of the present study was to evaluate the effect of the aluminum chloride hemostatic agent on the gingival margin microleakage of class V (Cl V) composite resin restorations bonded with all-in-one adhesive. Study design: Cl V cavities were prepared on the buccal surfaces of 60 sound bovine permanent incisors. Gingival margins of the cavities were placed 1.5 mm apical to the cemento-enamel junction (CEJ). The teeth were randomly divided into two groups of 30. In group 1, the cavities were restored without the application of a hemostatic agent; in group 2, the ca…
Facilitating domain wall injection in magnetic nanowires by electrical means
2020
We investigate how to facilitate the injection of domain walls in chiral ferromagnetic nanowires by electrical means. We calculate the critical current density above which domain walls are injected into the nanowire depending on the material parameters and the source of interaction including spin-transfer torques as well as spin-orbit torques. We demonstrate that the Dzyaloshinskii-Moriya interaction can significantly reduce the required critical current to inject the types of domain walls favored by the Dzyaloshinskii-Moriya interaction. We find that in chiral magnets it is only possible to shed a single domain wall by means of spin-orbit torques, as they modify the ground state orientatio…
Mechanical and microstructural characterization of friction stir welded skin and stringer joints
2013
A microstructural and mechanical investigation on lap joints welded by friction stir welding and made out of a 7075-T6 stringer and a 2024-T4 skin is presented. In particular, the metallurgical and mechanical properties of joints have been studied at different tool feed rates (V = 35, 50, 100 mm/min) and constant rotation speed (R = 500 r/min). Temperature distributions have been monitored during the process. It is found that in the welded area, the recrystallized zone (nugget) has an average grain size of about 3 µm and exhibits coarsened MgZn2 particles on grain boundaries. The maximum values of microhardness in the welded skin increase with the process temperature, while they just sligh…
Improved FE model for simulation of friction stir welding of different materials
2010
Abstract One of the most relevant aspects of friction stir welding is the possibility to weld different materials. In the present paper, the authors present an improved continuum finite element model for the simulation of friction stir welding processes aimed to obtain T joints, made of a stringer in AA7175-T73511 and of a skin in AA2024-T4. The model, taking into account the thermomechanical behaviours of the two different materials, is utilised to study the occurring material flow and residual stress state. Numerical results are compared with experimental observations: the model is able to predict the material flow, obtaining important information on the joint failure mode.
Theoretical elastoplastic buckling of stringer stiffened cylindrical shells
1985
Abstract A linear analysis method is offered to predict the theoretical elastoplastic buckling of stringer stiffened cylindrical shells subjected to longitudinal loading. Welding residual stresses are taken into account in the calculation, but effects of geometrical imperfections and pre-buckling displacements are ignored. The examples analysed show a good correlation between the analytical results and those obtained experimentally with stocky models of moderate geometrical imperfections.
Optimal Set Points Regulation of Distributed Generation Units in Micro-grids under Islanded Operation
2010
The present work studies the problem of optimizing the power production levels of dispersed generation units in islanded microgrids. The problem is intrinsically multi-objective with non linear objectives and constraints, thus the solution approach is based on evolutionary optimization and uses the Non dominated Sorting Genetic Algorithm II. The objectives are calculated based on the solution of the load flow problem. The latter problem is more complicated when in the considered system a physical node with a sufficiently large production capability is not available, because all the generation node of the systems have similar and limited generation capability. In this paper, the issue has be…
Unraveling the Reaction Mechanism of Enzymatic C5-Cytosine Methylation of DNA. A Combined Molecular Dynamics and QM/MM Study of Wild Type and Gln119 …
2016
M.HhaI is a DNA methyltransferase from Haemophilus hemolyticus that catalyzes the transfer of a methyl group from S-adenosyl-l-methionine (SAM) to the C5 position of a cytosine. This enzyme is a paradigmatic model for C5 DNA methyltransferases due to its major homology to mammalian enzymes and to the availability of high-resolution structures of the DNA–enzyme complex. In spite of the number of experimental and theoretical analyses carried out for this system, many mechanistic details remain unraveled. We have used full atomistic classical molecular dynamics simulations to explore the protein–SAM–DNA ternary complex, where the target cytosine base is flipped out into the active site for bot…
String kernels and high-quality data set for improved prediction of kinked helices in α-helical membrane proteins.
2011
The reasons for distortions from optimal α-helical geometry are widely unknown, but their influences on structural changes of proteins are significant. Hence, their prediction is a crucial problem in structural bioinformatics. For the particular case of kink prediction, we generated a data set of 132 membrane proteins containing 1014 manually labeled helices and examined the environment of kinks. Our sequence analysis confirms the great relevance of proline and reveals disproportionately high occurrences of glycine and serine at kink positions. The structural analysis shows significantly different solvent accessible surface area mean values for kinked and nonkinked helices. More important, …