Search results for "stroke."

Risk and Benefit of STA/MCA Anastomoses

1985

The advantage of EC/IC operation has not yet been proved unequivocally enough. We therefore attempted to analyze our cases in order to establish the possible benefit and risk of the operation. We compared the outcome of the operated and nonoperated patients with reference to the literature.

<title>Near-infrared spectroscopy (NIRS) as a diagnostic tool in patients with suspected stroke or traumatic brain injury</title>

2001

Near-Infrared Spectroscopy (NIRS) as a diagnostic tool in patients with suspected stroke or brain injury S. Goldberg, C. Lott, M. Ostermeyer, H.-J. Hennes Absorption of Near-Infrared (NIR) light in the brain is mainly caused by hemoglobin. Superficial intracranial hematoma with a higher concentration of hemoglobin causes a higher absorption in NIRS. The existence of hemorrhage can be demonstrated by the difference of optical density, comparing identical measuring points at both hemispheres of the brain: absorption of NIR light is greater at the side of the hemorrhage, causing less reflection in NIRS. In a prospective, blinded study, 100 patients who were scheduled for CCT-scan for brain inj…

Response to Letter Regarding Article, “The Inflammatory Hypothesis: Any Progress in Risk Stratification and Therapeutic Targets?”

2007

We thank Drs Ridker and Everett for their interest in our work,1 and we commend Ridker’s pioneering work describing an association between C-reactive protein (CRP) and the risk of myocardial infarction or stroke. Subsequent studies have both confirmed and refuted these original observations. The former studies “controlled” or “adjusted” for fewer other risk factors; when they did so, they dichotomized variables (a weaker approach) rather than using them as continuous variables. By contrast, the latter studies have incorporated adjustments for other markers (especially of abdominal obesity, because visceral fat …

Environmental stressors and cardiovascular risk: Impact of environmental noise exposure on vascular oxidative stress and damage

2018

Epidemiological studies have demonstrated that traffic noise exposure is associated with cardiovascular diseases such as arterial hypertension, myocardial infarction and stroke. Persistent chronic noise exposure increases the risk of cardiovascular and metabolic diseases such as arterial hypertension, coronary artery disease, diabetes and stroke. Large epidemiological studies (reviewed in Munzel et al. Eur. Heart J. 2017, 38 (8):550–556) point towards a link between the incidence of ischemic heart diseases and exposure to noise, supporting its role as an independent cardiovascular risk factor. Recently, the underlying molecular mechanisms leading to noise-dependent adverse effects on the va…

Use of central venous catheter and increased risk of ischemic stroke

2020

IMPACT OF CAROTID ENDARTERECTOMY ON COGNITIVE PERFORMANCE AND DEPRESSIVE SYMPTOMS

2016

OBJECTIVES: This study aims to evaluate the impact of carotid endarterectomy (CEA) on cognitive performance in patients with severe carotid disease and depressive symptoms, and to explore the possible associations between certain demographics, clinical characteristics, and cognitive function and depression. MATERIALS AND METHODS: The study included 48 patients, who were referred for endarterectomy. Cognitive function was assessed using the Montreal Cognitive Assessment (MoCA) scale, while depressive symptoms were assessed using the patient health questionnaire(PHQ-9) scale. An assessment of cognitive and depressive symptoms was performed 1–3 days before surgery, and then six months after. R…

Comparison of TMS-induced arm acticvation and upper limb functional tests in hemiparetic stroke

2013

Stroke has a major impact in the total cost of healthcare in the Western world as stroke is the most common cause of long-term disability [1]. In attempts to enhance motor recovery after stroke effective treatment strategies have been developed in recent years. Appropriate evaluation of the intervention programs requires comprehensive and accurate assessment of the residual abnormal function. In the present study we compare two well-known clinical functional scoring tests developed for the assessment of hemiparetic upper limb function due to stroke and navigated transcranial magnetic stimulation (nTMS), which measures involuntary target muscle response to cortical stimulation. The aim is to…

Stroke--a medical emergency.

1999

Stroke is the third leading cause of death and number one cause of disability in industrialised countries. A number of new therapeutic approaches are currently in development for use in the acute phase of ischaemic stroke and all trials have, to date, demonstrated the importance of early diagnosis and subsequent initiation of treatment. It is well known that, for most patients, there is a long delay between the onset of symptoms and the start of treatment. A number of factors are responsible for this time delay: signs and symptoms often go unrecognised by patients, relatives, and bystanders and, unlike trauma or myocardial infarction, stroke is not given a high priority by medical staff. St…

Meta-analysis of the efficacy of different training strategies in animal models of ischemic stroke.

2013

Background and Purpose— Although several studies have shown beneficial effects of training in animal stroke models, the most effective training strategy and the optimal time to initiate training have not been identified. The present meta-analysis was performed to compare the efficacy of different training strategies and to determine the optimal time window for training in animal stroke models. Methods— We searched the literature for studies analyzing the efficacy of training in animal models of ischemic stroke. Training was categorized into forced physical training, voluntary physical training, constraint-induced movement therapy, and skilled reaching training. Two reviewers independently …

Tailoring anticoagulant treatment of patients with atrial fibrillation using a novel bleeding risk score

2021

ObjectivesCurrent international guidelines advocate the application of bleeding risk scores only to identify modifiable risk factors, but not to withhold treatment in patients at high risk of bleeding. VTE-BLEED (ActiVe cancer, male with uncontrolled hyperTension, anaEmia, history of BLeeding, agE and rEnal Dysfunction) is a simple bleeding risk score that predicts major bleeding (MB) in patients with venous thromboembolism, but has never been evaluated in patients with atrial fibrillation (AF). We sought to evaluate VTE-BLEED in patients with AF included in the Randomised Evaluation of Long-term anticoagulant therapY (RE-LY) trial, to assess whether score classes (high vs low bleeding risk…