Search results for "structures"
showing 10 items of 4815 documents
Elevated protein carbonyl and HIF-1α levels in eyes with proliferative diabetic retinopathy.
2013
Purpose: To evaluate the role of protein carbonyls and hypoxia inducible factor-1a (HIF-1a) in diabetic eyes with proliferative diabetic retinopathy (PDR). Methods: Prospective consecutive controlled observational study was performed. Vitreous samples were collected at the start of the 3-ppp vitrectomy. Protein carbonylation analysis was performed by Western blotting with antibody against 2,4-Dinitrophenol (anti-DNP), following derivatization of protein carbonyls with 2,4 Dinitrophenylhydrazine (DNHP). Protein carbonylation was quantified by scanning densitometry analysis and relativized to the total amount of protein into the ponceau staining of membranes. Vitreous HIF-1 a was determined w…
Monocular Versus Binocular Calibrations in Evaluating Fixation Disparity With a Video-Based Eye-Tracker
2015
When measuring fixation disparity (an oculomotor vergence error), the question arises as to whether a monocular or binocular calibration is more precise and physiologically more appropriate. In monocular calibrations, a single eye fixates on a calibration target that is taken as having been projected onto the center of the fovea; the corresponding vergence state represents the heterophoria (the resting vergence position), which has no effect on the calibration procedure. In binocular calibrations, a vergence error may be present and may affect the subsequent measurement of the fixation disparity during binocular recordings. This study includes a test of the precision of both monocular and …
Long-term comparison of corneal aberration changes after laser in situ keratomileusis: mechanical microkeratome versus femtosecond laser flap creatio…
2010
Purpose To compute and compare visual acuity, refractive outcomes, and anterior corneal aberration changes after myopic laser in situ keratomileusis (LASIK) with flap creation by a mechanical microkeratome and by a femtosecond laser. Setting Private practice refractive surgery center, Valencia, Spain. Design Comparative case series. Methods Patients were assigned to have LASIK flap creation with a mechanical microkeratome (Carriazo-Barraquer) or a femtosecond laser (IntraLase). The Visx S2 excimer laser was used for myopic ablation in all cases. Main outcome measures included uncorrected and corrected distance visual acuities and the defocus equivalent. Higher-order aberrations (HOAs) were …
Visual performance of two simultaneous vision multifocal contact lenses
2012
Purpose To evaluate and compare the visual performance of two simultaneous vision multifocal contact lenses (CLs). Methods In this cross-over study design 20 presbyopic subjects were fitted with two different simultaneous vision multifocal CLs (the PureVision Multifocal Low Add and Acuvue Oasys for Presbyopia) in random order. After 1 month, binocular distance visual acuity (BDVA) under photopic (85 cd/m2) and mesopic (3 cd/m2) conditions, binocular near visual acuity (BNVA), binocular distance contrast sensitivity function (CSF) under photopic and mesopic conditions, binocular near CSF and defocus curve were measured. Subjects were then refitted with the alternative correction and the proc…
Quality of vision with the Acri. Twin asymmetric diffractive bifocal intraocular lens system.
2007
To assess the quality of vision in patients who had implantation of asymmetric Acri. Twin bifocal diffractive intraocular lenses (IOLs) by evaluating distance and near visual acuities and photopic and mesopic contrast sensitivity under monocular and binocular conditions.Fernández-Vega Ophthalmological Institute, Oviedo, Spain.The study comprised 343 consecutive patients who had bilateral implantation of the Acri. Twin system: a distance-weighted 737D IOL and a near-weighted 733D IOL. Monocular and binocular best corrected distance visual acuities, best distance corrected near visual acuity, and distance contrast sensitivity under photopic (85 cd/m(2)) and mesopic (5 cd/m(2)) conditions were…
Visual function after implantation of a diffractive aspheric trifocal intraocular lens
2016
Purpose To evaluate distance, intermediate, and near vision after bilateral implantation of a diffractive aspheric trifocal intraocular lens (IOL). Methods This study enrolled 204 eyes of 102 patients who had bilateral implantation of the AT LISA tri 839MP IOL. Monocular and binocular uncorrected distance visual acuity (UDVA) and corrected distance visual acuity (CDVA) (4 meters), monocular and binocular uncorrected near visual acuity (UNVA) and distance-corrected near visual acuity (DCNVA) (30, 40 centimeters), binocular uncorrected intermediate visual acuity (UIVA) and distance-corrected intermediate visual acuity (DCIVA) (50, 60, 70 centimeters), the defocus curve, and binocular photopic…
Diurnal variations in visual performance for disposable contact lenses.
2013
The purpose of this study is to compare the visual performance provided by different daily disposable contact lenses and to analyze its variation over time.Visual performance was evaluated in terms of visual acuity (VA) and contrast sensitivity (CS) in 15 myopic subjects (-0.50 to -4.00 diopters) who had been previously fitted with each one of the following seven types of soft contact lenses: DAILIES TOTAL1 (Alcon, Forth Worth, TX), DAILIES AquaComfort Plus (Alcon), 1-DAY ACUVUE TruEye (JohnsonJohnson Vision Care, Jacksonville, FL), 1-DAY ACUVUE MOIST (JohnsonJohnson Vision Care), SofLens daily disposable (BauschLomb, Rochester, NY), Proclear 1 Day (CooperVision, Fairport, NY), and Clariti …
The effects of social pressure and emotional expression on the cone of gaze in patients with social anxiety disorder
2016
Abstract Background and objectives Patients with social anxiety disorder suffer from pronounced fears in social situations. As gaze perception is crucial in these situations, we examined which factors influence the range of gaze directions where mutual gaze is experienced (the cone of gaze). Methods The social stimulus was modified by changing the number of people (heads) present and the emotional expression of their faces. Participants completed a psychophysical task, in which they had to adjust the eyes of a virtual head to gaze at the edge of the range where mutual eye-contact was experienced. Results The number of heads affected the width of the gaze cone: the more heads, the wider the …
Quantifying the Wollaston Illusion
2020
In the early 19th century, William H. Wollaston impressed the Royal Society of London with engravings of portraits. He manipulated facial features, such as the nose, and thereby dramatically changed the perceived gaze direction, although the eye region with iris and eye socket had remained unaltered. This Wollaston illusion has been replicated numerous times but never with the original stimuli. We took the eyes (pupil and iris) from Wollaston’s most prominent engraving and measured their perceived gaze direction in an analog fashion. We then systematically added facial features (eye socket, eyebrows, nose, skull, and hair). These features had the power to divert perceived gaze direction by…
Who is looking at me? The cone of gaze widens in social phobia
2011
Gaze direction is an important cue that regulates social interactions and facilitates joint attention. Although humans are very accurate in determining gaze directions in general, they have a surprisingly liberal criterion for the presence of mutual gaze. Using an established psychophysical task that required observers to adjust the eyes of a virtual head to the margins of the area of mutual gaze, we examined whether the resulting cone of gaze is altered in people with social phobia. It turned out that during presence of a second virtual person, the gaze cone's width was specifically enlarged in patients with social phobia as compared to healthy controls. The size of this effect was correla…