Search results for "substance"
showing 10 items of 1728 documents
Implementation of Substitution Treatment in Finland: Beyond Rationalisation and Medicalisation
2011
AIMS Finnish treatment of drug abuse has during the last two decades shifted from a predominantly psychosocial approach to a more medical mode. This is especially evident in the rapid implementation of substitution treatments (STs). My aim is to show that labelling this development as ‘medicalisation’ or ‘rationalisation’ as a form of medical progress will not increase our understanding of the change. MATERIAL AND DESIGN I analysed texts from several periodicals with psychosocial, social policy and medical perspectives between 1997 and 2005. Four basic conceptual and argumentative underpinnings emerged which gave credence to the medical and rationalapproach, and the validity of these four e…
Severe corneal complications following vitreoretinal surgery
2011
Severe corneal complications following vitreoretinal surgery. annual meeting of the association-for-research-in-vision-and-ophthalmology (ARVO)
Chronic ethanol exposure alters the levels, assembly, and cellular organization of the actin cytoskeleton and microtubules in hippocampal neurons in …
2010
The organization and dynamics of microtubules (MTs) and the actin cytoskeleton are critical for the correct development and functions of neurons, including intracellular traffic and signaling. In vitro ethanol exposure impairs endocytosis, exocytosis, and nucleocytoplasmic traffic in astrocytes and alters endocytosis in cultured neurons. In astrocytes, these effects relate to changes in the organization and/or function of MTs and the actin cytoskeleton. To evaluate this possibility in hippocampal cultured neurons, we analyzed if chronic ethanol exposure affects the levels, assembly, and cellular organization of both cytoskeleton elements and the possible underlying mechanisms of these effec…
DETERMINATION OF ABUSED SUBSTANCES IN BIOLOGICAL MATRICES FOR TOXICOLOGICAL AND FORENSIC PURPOSES
2019
During the year 2017, a research work was carried out at the Department of laboratory diagnostics - Toxicology and Biochemistry U.O.S. of ASP 6 in Palermo. The purpose of this investigation was to perform a second level analysis in order to look for abuse drugs. The sample used consisted of 73 serum tubes, which had previously tested positive for screen- ing tests. The result of the analysis of these samples revealed a false positivity in most cases. From the information gathered through the sampling reports, it appears that the age group with several drivers, who are subject to checks by the traffic police, is the one from 17 to 30 years, with 35 samples analysed (48%). It also emerged tha…
Funcionamiento familiar, autoestima y consumo de sustancias en adolescentes: un modelo de mediación Family functioning, self-esteem and substance use…
2007
OBJETIVO: Analizar las relaciones directas e indirectas entre el funcionamiento familiar, la autoestima considerada desde una perspectiva multidimensional (autoestima familiar, escolar, social y física) y el consumo de sustancias. MATERIAL Y MÉTODOS: Los datos se recogieron durante el año escolar 2003-2004 y corresponden a dos muestras independientes de adolescentes españoles (n1= 414, Castilla y León; n2= 625, Comunidad Valenciana). Para el análisis de datos se utilizó la técnica estadística de ecuaciones estructurales y se siguió el procedimiento de análisis de efectos mediadores de Holmbeck (1997). RESULTADOS: La autoestima media significativamente la influencia del funcionamiento famili…
Cannabis and Other Hallucinogenic Substance use and Abuse in the Context of COVID-19 Related Stressors
2022
Ievads: Kanabinoīdi ir pasaulē visvairāk lietotā narkotiskā viela.. PVO ģenerāldirektors 2020. gada 11. martā pasludināja COVID-19 pandēmiju. COVID-19 pandēmijas laikā daudzas valstis ieviesa ierobežojumus, lai ierobežotu jaunā koronavīrusa izplatīšanos, savukārt šie ierobežojumi var izraisīt garīgās veselības problēmas. Vairāki pētījumi liecina, ka COVID-19 izraisītā stresa pārvarēšanai tika lietota marihuāna vai citi halucinogēni. Mērķi: Tika sagatavots literatūras apskats, kurā apkopota jaunākā literatūra par vielu lietošanu pandēmijas laikā un kas ļauj salīdzināt to ar aptaujas datiem. Pētījuma, kas tika veikts no novembra līdz februārim, mērķis bija novērtēt riska un aizsargājošos fakt…
Rikoksista tuomitut naiset : yhteisöstä erottaminen ja takaisinliittymisen mahdollisuudet
2019
Tutkimus käsittelee yhteisöstä erottamisen ja siihen takaisinliittymisen mahdollisuuksia rikostaustaisten naisten elämässä. Tutkimuksen kohteena ovat rikostaustaisten naisten kertomukset elämänkulustaan. Tutkimuksessa analysoidaan naisten kertomuksia siirtymäriittiteorian eli yhteisöstä erottamisen, liminaalin ja takaisinliittämisen näkökulmasta. Aineisto on kerätty haastattelemalla 18 naista, jotka haastatteluhetkellä olivat joko suorittamassa vankeusrangaistustaan, ehdonalaisen vapauden valvonnassa tai rangaistuksensa suorittaneet. Aineiston analyysissa on käytetty narratiivista lähestymistapaa sekä Greimasin aktanttimallia. Aineiston analyysissa esiin nousevia keskeisiä teemoja ovat päih…
A fluorescence study of the loading and time stability of doxorubicin in sodium cholate/PEO-PPO-PEO triblock copolymer mixed micelles
2019
Abstract Hypothesis Doxorubicin hydrochloride (DX) is one of the most powerful anticancer agents though its clinical use is impaired by severe undesired side effects. DX encapsulation in nanocarrier systems has been introduced as a mean to reduce its toxicity. Micelles of the nonionic triblock copolymers of poly(ethylene oxide) (PEO) and poly(propylene oxide) (PPO) (PEO-PPO-PEO), are very promising carrier systems. The positive charge of DX confines the drug to the hydrophilic corona region of the micelles. The use of mixed micelles of PEO-PPO-PEO copolymers and a negatively charged bile salt should favour the solubilization of DX in the apolar core region of the micelles. Experiments We st…
A firm's activity in social media and its relationship with corporate reputation and firm performance
2015
There is growing debate about whether companies’ investments in social media really pay off. This research attempts to contribute to this discussion by investigating the relationship between a firm’s social media activity and two outcomes, namely, company reputation and firm financial performance. Two propositions are developed based on theory and tested with a sample of 59 companies. The findings suggest that a firm’s social media activity is only partially linked with its financial performance and is not linked with corporate reputation. The implications of the research suggest that little is known about the relationships between a firm’s social media activity and corporate reputation and…
Mandibular involvement of solitary plasmocytoma : a case report
2007
Plasma cell neoplasms (multiple myeloma, solitary plasmocytoma of bone and extra medullar plasmocytoma) are characterized by a monoclonal neoplastic proliferation of plasma cells. Solitary plasmocytoma of bone (SPB) is a localized form of them. SPB is most frequently seen in vertebrae and secondarily in long bones. Its presence in jaws is extremely rare and when it is seen, angulus and ramus mandible are most common sites of occurrence. Prognosis of SPB is worse than extra medullar plasmacytoma (EMP) and approximately 50% of SPB will transform to multiple myelom. A 76- year old woman consulted to our clinic with a chief complaint of slowly developed swelling in her mandible. She had an oper…