Search results for "sun"
showing 10 items of 935 documents
Coronaviral Ion Channels as Target for Chinese Herbal Medicine
2012
Traffic fundamentals for A22 Brenner freeway by microsimulation models.
La tesi di dottorato ha avuto come tema lo studio e l’applicazione di un modello di micro-simulazione del traffico in ambito autostradale. Essa si compone di quattro capitoli, con ognuno dei quali si è voluto sintetizzare e descrivere il lavoro di studio e ricerca svolto durante il suddetto corso di Dottorato di Ricerca. L’obiettivo principale del presente lavoro di tesi è stato quello di mettere a punto una metodologia finalizzata all’ottenimento delle relazioni fondamentali di deflusso in ambito autostradale attraverso il software di microsimulazione del traffico Aimsun. Come risulta infatti noto dalla letteratura scientifica, le relazioni fondamentali del deflusso sono utilizzate nel cam…
Capacity-based calculation of passenger car equivalents using traffic simulation at double-lane roundabouts
2018
Abstract Calculation of passenger car equivalents for heavy vehicles represents the starting point for the operational analysis of road facilities and other traffic management applications. This paper introduces a criterion to find the passenger car equivalents that reflect traffic conditions at double-lane roundabouts, where the capacity is typically estimated for each entry lane. Based on the equivalence defined by the proportion of capacity used by vehicles of different classes, the criterion implies a comparison between the capacity that would occur with a traffic demand of passenger cars only and the capacity reached beginning from a demand with a certain percentage of heavy vehicles. …
THE DURATION OF FIRM-DESTINATION EXPORT RELATIONSHIPS: EVIDENCE FROM SPAIN, 1997-2006
2012
I. INTRODUCTION The traditional trade literature that investigates aggregate trade flows emphasizes the sizeable increase in trade relationships since World War II and the remarkable persistence of trade flows. However, recent microlevel studies point out that under the stable aggregate trade flows there is a rich dynamics at firm- and/or product-level with a high turnover. In fact, international-market presence is often a transitory and an uncommon phenomenon. At any period, only a small percentage of home-based firms participate in trade and exporting firms are different from non-exporters (larger, more productive, etc.). Moreover, there is much persistence in exporting status; being an e…
Design and experimental test of a low costweather buoy
2013
The importance of prevention plans based on realistic inundation scenarios was dramatically highlighted by the Indian Ocean Tsunami of 26 December 2004. But also in the Mediterranean, sea storms basin are a quite common event especially during winter months. These scenarios are generally based on numerical models of tsunami wave propagation that can become more realistic and effective when calibrated with the distribution of true data acquired by special weather buoy. In this paper we present the result of an experimental weather buoy built by DEIM of University of Palermo, that is characterized by small cost and big versatility.
2021
Tyrosine kinase inhibitors (TKIs) and immune checkpoint inhibitors predominate as first-line therapy options for renal cell carcinoma. When first-line TKI therapy fails due to resistance development, an optimal second-line therapy has not yet been established. The present investigation is directed towards comparing the anti-angiogenic properties of the TKIs, sorafenib and axitinib on human endothelial cells (HUVECs) with acquired resistance towards the TKI sunitinib. HUVECs were driven to resistance by continuously exposing them to sunitinib for six weeks. They were then switched to a 24 h or further six weeks treatment with sorafenib or axitinib. HUVEC growth, as well as angiogenesis (tube…
Simulation of the Propagation of Tsunamis in Coastal Regions by a Two-Dimensional Non-Hydrostatic Shallow Water Solver
2017
Due to the enormous damages and losses of human lives in the inundated regions, the simulation of the propagation of tsunamis in coastal areas has received an increasing interest of the researchers. We present a 2D depth-integrated, non- hydrostatic shallow waters solver to simulate the propagation of tsunamis, solitary waves and surges in coastal regions. We write the governing continuity and momentum equations in conservative form and discretize the domain with unstructured triangular Generalized Delaunay meshes. We apply a fractional- time-step procedure, where two problems (steps) are consecutively solved. In the first and in the second step, we hypothesize a hydrostatic and a non-hydro…
Tourist consumption behaviour in a sun and beach Mediterranean mature destination and its implications for local development
2015
El comercio de buena parte de los destinos maduros de sol y playa, a lo largo de la orilla norte del mar Mediterráneo, ha tenido que afrontar varios años de rendimientos decrecientes a causa de la crisis económica que han sufrido los principales mercados de origen (nacional e internacional), y a la competencia de nuevas formas y destinos turísticos. En la mayoría de los casos, se trata de núcleos urbanos con un comercio estacional de proximidad que solo se activa durante la breve temporada alta. El resto del comercio urbano apenas se beneficia del consumo de un turismo que permanece recluido en el espacio de playa. En este trabajo se presentan los resultados de un análisis empírico de los h…
Análisis del comportamiento de la demanda de turismo rural desde la experiencia de la comarca El Alto Palancia
2004
This study is intended to delve into the tastes and preferences of tourists visiting rural areas in Spain as an alternative to the traditional sun and beach holiday that dominates Spanish tourism. This paper is focused on the demand side of rural tourism; more specifically the extent to which tourists visiting a Spanish rural area. El Alto Palancia region, exhibit different behaviours depending on age, gender, incomes and educational background. The homogeneity of behaviour across several categories of tourists was tested in two sets of variables. First, «interest in certain resources associated with rural tourism», focused on natural and architectural resources that sustains the tourist's …