Search results for "suo"
showing 10 items of 3817 documents
ISOLAMENTO DI BATTERI DEGRADATORI DI ORGANOFOSFORICI DA SUOLI MEDITERRANEI
2011
I pesticidi organofosforici sono utilizzati per migliorare la produzione agricola e per il controllo dei parassiti. Nonostante i benefici effetti sull’agricoltura, i pesticidi danneggiano gli organismi viventi in quanto interferiscono con i processi metabolici e si diffondono nelle matrici ambientali, tra le quali il suolo, che rappresenta un’importante risorsa. Lo scopo del presente lavoro è stato quello di studiare la biodiversità di batteri degradatori di organofosforici, in suoli mediterranei, differenti per il tipo di coltura e le pratiche agronomiche. I batteri rappresentano infatti, un’utile strumento nella bonifica di aree contaminate. Dai suoli, sono stati isolati 47 ceppi, capaci …
Impact of Age and Comorbidity on Multimodal Management and Survival from Colorectal Cancer : A Population-Based Study
2021
This retrospective population-based study examined the impact of age and comorbidity burden on multimodal management and survival from colorectal cancer (CRC). From 2000 to 2015, 1479 consecutive patients, who underwent surgical resection for CRC, were reviewed for age-adjusted Charlson comorbidity index (ACCI) including 19 well-defined weighted comorbidities. The impact of ACCI on multimodal management and survival was compared between low (score 0–2), intermediate (score 3) and high ACCI (score ≥ 4) groups. Changes in treatment from 2000 to 2015 were seen next to a major increase of laparoscopic surgery, increased use of adjuvant chemotherapy and an intensified treatment of metastatic dis…
Maalaisliiton/Keskustan kunta ja kuntalaisuus liikkeessä? : käsitehistoriallinen näkökulma Maalaisliiton/Keskustan kuntapoliittisiin asiakirjoihin 19…
2014
Tutkimukseni tarkoituksena on selvittää, mikä on Maalaisliiton/Keskustan kunta- ja kuntalaisuuskäsitys. Tarkastelen työssäni kunnan ja kuntalaisuuden saamia merkityksiä käsitehistoriallisesta näkökulmasta. Tutkimukseni teoriatausta rakentuu Reinhart Koselleckin ajatuksiin käsitehistoriasta. Pro-gradu tutkielman aineisto koostuu Maalaisliiton/Keskustan kuntapoliittisista ohjelmista. Kunta- ja kuntalaisuus ovat saaneet ohjelmissa uusia sisältöjä ja merkityksiä, vaikka tietyt perusasiat säilyvät aina 1940- luvun lopulta 2008 vuoden ohjelmaan saakka. Aineistoni osoittaa, että käsitteiden ympärillä on havaittavissa poliittista kamppailua. Tämä ilmenee esimerkiksi kunta- valtiosuhteen kautta. Puo…
Rats bred for low aerobic capacity become promptly fatigued and have slow metabolic recovery after stimulated, maximal muscle contractions.
2012
AIM. Muscular fatigue is a complex phenomenon affected by muscle fiber type and several metabolic and ionic changes within myocytes. Mitochondria are the main determinants of muscle oxidative capacity which is also one determinant of muscle fatigability. By measuring the concentrations of intracellular stores of high-energy phosphates it is possible to estimate the energy production efficiency and metabolic recovery of the muscle. Low intrinsic aerobic capacity is known to be associated with reduced mitochondrial function. Whether low intrinsic aerobic capacity also results in slower metabolic recovery of skeletal muscle is not known. Here we studied the influence of intrinsic aerobic capac…
National context and teacher characteristics : Exploring the critical non-cognitive attributes of novice teachers in four countries
2018
The purpose of this article was to examine what education professionals in four countries (England, Finland, Malawi, and Oman) deemed as the critical (i.e., most important for effective teaching) non-cognitive attributes of novice teachers. Results from an iterative comparative case study showed that participants consistently judged certain attributes of novice teachers as critical, i.e., empathy, organization, and resilience. However, there was also differential importance placed on teachers’ relationships with the community, reflecting theorized cultural differences. The findings provide new insight into how national and cultural context are associated with the perceptions of the critical…
Ideal cardiovascular health and risk of acute myocardial infarction among Finnish men
2019
Background and aims: Acute myocardial infarction (AMI) is associated with high mortality globally and remains a public health burden. We sought to investigate the relation between the American Heart Association’s cardiovascular health metrics (CVH) and the risk of AMI among middle-aged Finnish men. Methods: We used the ongoing population-based Kuopio Ischaemic Heart Disease cohort study comprising men aged 40 to 62 years at baseline. The CVH metrics was computed among 2584 participants at baseline with health scores ranging from 0 to 7. This was categorized into three groups of CVH metrics as poor (0-2), intermediate (3-4) and ideal (≥5). Multivariate Cox regression models were used to esti…
EGFR gene copy number decreases during anti-EGFR antibody therapy in colorectal cancer
2018
Epidermal growth factor receptor (EGFR) gene copy number (GCN) increase is associated with a favorable anti-EGFR antibody treatment response in RAS wild-type metastatic colorectal cancer. However, there are limited and comparative data regarding the EGFR GCN in primary colorectal cancer tumors and corresponding metastases or the effect of anti-EGFR antibody treatment on EGFR GCN in recurrent disease. In addition, little is known about the potential EGFR GCN changes during anti-EGFR therapy in comparison with other treatment regimens. EGFR GCN was analyzed by EGFR immunohistochemistry-guided silver in situ hybridization in primary and corresponding recurrent local or metastatic tumors from 8…
Fungal Dysbiosis and Intestinal Inflammation in Children With Beta-Cell Autoimmunity
2020
Although gut bacterial dysbiosis is recognized as a regulator of beta-cell autoimmunity, no data is available on fungal dysbiosis in the children at the risk of type 1 diabetes (T1D). We hypothesized that the co-occurrence of fungal and bacterial dysbiosis contributes to the intestinal inflammation and autoimmune destruction of insulin-producing beta-cells in T1D. Fecal and blood samples were collected from 26 children tested positive for at least one diabetes-associated autoantibody (IAA, GADA, IA-2A or ICA) and matched autoantibody-negative children with HLA-conferred susceptibility to T1D (matched for HLA-DQB1 haplotype, age, gender and early childhood nutrition). Bacterial 16S and funga…
Short-term effects of Finnish sauna bathing on blood-based markers of cardiovascular function in non-naive sauna users
2018
Emerging evidence suggests that sauna bathing is associated with reduced risk of cardiovascular and all-cause mortality events. However, the biochemical pathways by which sauna bathing might confer its effects on cardiovascular function are not certain. We aimed to study the acute effects of Finnish sauna bathing on various blood-based cardiovascular biomarkers. The study included 102 non-naive sauna users (54% male) with mean age of 51.9 years, who had at least one cardiovascular risk factor. Participants underwent a 30-min single sauna session (mean temperature, 73 °C). Biochemical profiling was conducted before, immediately after sauna and 30-min post-sauna. Overall median N-terminal pro…
On-Ice and Off-Ice Fitness Profiles of Elite and U20 Male Ice Hockey Players of Two Different National Standards
2020
Vigh-Larsen, JF, Haverinen, MT, Panduro, J, Ermidis, G, Andersen, TB, Overgaard, K, Krustrup, P, Parkkari, J, Avela, J, Kyröläinen, H, and Mohr, M. On-ice and off-ice fitness profiles of elite and U20 male ice hockey players of two different national standards. J Strength Cond Res 34(12): 3369-3376, 2020-Differences in body composition and performance were investigated between elite and U20 male ice hockey players of 2 different national standards. One hundred seventy-nine players were recruited from the highest Finnish (n = 82) and Danish (n = 61) national level, as well as from 1 U20 team from Finland (n = 19) and Denmark (n = 17). Body composition and countermovement jump performance (CM…