Search results for "sws"
showing 5 items of 5 documents
Is Sleep Disruption a Cause or Consequence of Alzheimer’s Disease? Reviewing Its Possible Role as a Biomarker
2020
In recent years, the idea that sleep is critical for cognitive processing has gained strength. Alzheimer’s disease (AD) is the most common form of dementia worldwide and presents a high prevalence of sleep disturbances. However, it is difficult to establish causal relations, since a vicious circle emerges between different aspects of the disease. Nowadays, we know that sleep is crucial to consolidate memory and to remove the excess of beta-amyloid and hyperphosphorilated tau accumulated in AD patients’ brains. In this review, we discuss how sleep disturbances often precede in years some pathological traits, as well as cognitive decline, in AD. We describe the relevance of sleep to memory co…
Mosaic activating mutations in GNA11 and GNAQ are associated with phakomatosis pigmentovascularis and extensive dermal melanocytosis
2016
Common birthmarks can be an indicator of underlying genetic disease but are often overlooked. Mongolian blue spots (dermal melanocytosis) are usually localized and transient, but they can be extensive, permanent, and associated with extracutaneous abnormalities. Co-occurrence with vascular birthmarks defines a subtype of phakomatosis pigmentovascularis, a group of syndromes associated with neurovascular, ophthalmological, overgrowth, and malignant complications. Here, we discover that extensive dermal melanocytosis and phakomatosis pigmentovascularis are associated with activating mutations in GNA11 and GNAQ, genes that encode Gα subunits of heterotrimeric G proteins. The mutations were det…
Kognitīvās funkcijas normatīvi veseliem bērniem, bērniem ar CSWS sindromu un citiem epilepsijas traucējumiem
2021
Šajā darbā ir apskatītas kognitīvās funkcijas, kurās ietilpst atmiņa, uzmanība, uztvere, vadības funkcijas un valoda, kā arī plašāk apskatīta epilepsija, tās ārstēšana, CSWS sindroms (epilepsija ar nepārtrauktiem smailajiem viļņiem miega laikā), kā arī epilepsijas saistība ar kognitīvajām funkcijām un UDHS (uzmanības deficīta un hiperaktivitātes sindroms). Šī pētījuma mērķis un uzdevums ir izprast un izzināt, vai bērniem ar CSWS sindromu un citiem epilepsijas traucējumiem vizuālās uzmanības, vizuālās un verbālās darba atmiņas, uztveres, vadības un motoro funkciju līmeņi tiek prognozēti zemāki, vai būs izteiktākas uzvedības problēmas, īpaši agresivitāte un hiperaktivitāte, kā arī, vai būs iz…
Design of a 1 kW output power Folded Waveguide TWT operating in ka-band
2019
A Ka-band Serpentine Folded Waveguide Travelling Wave Tube (TWT) has been designed. The imposed design parameters values in terms of high power, high load, wide bandwidth, low weight, along with a structure manufactured with planar technique or by means of a micro milling process, have been obtained. Small signal simulations have been carried out with an in-house software for interaction impedance evaluation. The commercial electromagnetic simulation code CST Suite has been used for dispersion diagram prediction. An optimization of the one-dimensional software, normally used for large-signal simulation in coupled cavity TWTs (“Computer Program for Analysis of Coupled-cavity Travelling-wave-…
Female sex workers' use of mobile phones in India: Lessons in effective engagement
2019
Despite the widespread impact of mobile phone technology, research on female sex workers’ (FSWs) access and use of this technology is sparse. This study aimed to document FSWs’ subjective perceptions of the benefits of mobile phone technology as well as examine the potential for its use by nongovernmental organizations (NGOs). Employing a phenomenological study built on in-depth qualitative interviews and focus group discussions with 67 FSWs and 18 staff and leaders from local NGOs in Mumbai and various locations of the Karnataka State in India between January and May 2015. Findings revealed complex trajectories for FSWs regarding accessing, learning about, and using mobile phone technology…