Search results for "tabac"
showing 10 items of 131 documents
The 15-Country Collaborative Study of Cancer Risk among Radiation Workers in the Nuclear Industry: Estimates of Radiation-Related Cancer Risks
2007
International audience; A 15-Country collaborative cohort study was conducted to provide direct estimates of cancer risk following protracted low doses of ionizing radiation. Analyses included 407,391 nuclear industry workers monitored individually for external radiation and 5.2 million person-years of follow-up. A significant association was seen between radiation dose and all-cause mortality [excess relative risk (ERR) 0.42 per Sv, 90% CI 0.07, 0.79; 18,993 deaths]. This was mainly attributable to a dose-related increase in all cancer mortality (ERR/Sv 0.97, 90% CI 0.28, 1.77; 5233 deaths). Among 31 specific types of malignancies studied, a significant association was found for lung cance…
Maternal post-natal tobacco use and current parental tobacco use is associated with higher body mass index in children and adolescents: an internatio…
2015
Background: We investigated whether maternal smoking in the first year of life or any current parental smoking is associated with childhood or adolescent body mass index (BMI). Methods: Secondary analysis of data from a multi-centre, multi-country, cross-sectional study (ISAAC Phase Three). Parents/guardians of children aged 6-7 years completed questionnaires about their children's current height and weight, whether their mother smoked in the first year of the child's life and current smoking habits of both parents. Adolescents aged 13-14 years completed questionnaires about their height, weight and current parental smoking habits. A general linear mixed model was used to determine the asso…
I traffici illeciti nel mediterraneo e le organizzazioni criminali transnazionali. Una introduzione alla ricerca NESMeS
2019
1. I movimenti nel Mediterraneo fra ieri e oggi. – 2. L’emersione delle organizzazioni poli-criminali. – 3. Una verifica sulle tipologie di organizzazioni criminali operanti nel Mediterraneo. – 4. Le risposte normative di contrasto ai traffici illeciti: l’armonizzazione di matrice europea. – 5. La rilevanza della relazione fra traffici illeciti e organizzazioni criminali nelle fonti sovranazionali. – 6. Focus: Tratta di esseri umani e organizzazioni criminali in cinque sistemi penali europei (Italia, Portogallo, Grecia, Spagna, Germania). – 7. Indicazioni di sintesi dalla ricerca NESMeS. 1. The movements in the Mediterranean between yesterday and today. - 2. The emergence of poly-criminal o…
Metabolic stasis in an ancient symbiosis: genome-scale metabolic networks from two Blattabacterium cuenoti strains, primary endosymbionts of cockroac…
2012
Abstract Background Cockroaches are terrestrial insects that strikingly eliminate waste nitrogen as ammonia instead of uric acid. Blattabacterium cuenoti (Mercier 1906) strains Bge and Pam are the obligate primary endosymbionts of the cockroaches Blattella germanica and Periplaneta americana, respectively. The genomes of both bacterial endosymbionts have recently been sequenced, making possible a genome-scale constraint-based reconstruction of their metabolic networks. The mathematical expression of a metabolic network and the subsequent quantitative studies of phenotypic features by Flux Balance Analysis (FBA) represent an efficient functional approach to these uncultivable bacteria. Resul…
Unraveling assemblage, functions and stability of the gut microbiota of Blattella germanica by antibiotic treatment
2020
Symbiosis between prokaryotes and eukaryotes is a widespread phenomenon that has contributed to the evolution of eukaryotes. In cockroaches, two types of symbionts coexist: an endosymbiont in the fat body (Blattabacterium), and a rich gut microbiota. The transmission mode of Blattabacterium is vertical, while the gut microbiota of a new generation is mainly formed by bacterial species present in feces. We have carried out a metagenomic analysis of Blattella germanica populations, treated and non-treated with two antibiotics (vancomycin and ampicillin) over two generations to (1) determine the core of bacterial communities and potential functions of the gut microbiota and (2) to gain insight…
Revisiting Plant Plasma Membrane Lipids in Tobacco: A Focus on Sphingolipids
2016
International audience; The lipid composition of plasma membrane (PM) and the corresponding detergent-insoluble membrane (DIM) fraction were analyzed with a specific focus on highly polar sphingolipids, so-called glycosyl inositol phosphorylceramides (GIPCs). Using tobacco (Nicotiana tabacum) 'Bright Yellow 2' cell suspension and leaves, evidence is provided that GIPCs represent up to 40 mol % of the PM lipids. Comparative analysis of DIMs with the PM showed an enrichment of 2-hydroxylated very-long-chain fatty acid-containing GIPCs and polyglycosylated GIPCs in the DIMs. Purified antibodies raised against these GIPCs were further used for immunogold-electron microscopy strategy, revealing …
Nitric oxide inhibits the ATPase activity of the chaperone-like AAA+ ATPase CDC48, a target for S-nitrosylation in cryptogein signalling in tobacco c…
2012
NO has important physiological functions in plants, including the adaptative response to pathogen attack. We previously demonstrated that cryptogein, an elicitor of defence reaction produced by the oomycete Phytophthora cryptogea , triggers NO synthesis in tobacco. To decipher the role of NO in tobacco cells elicited by cryptogein, in the present study we performed a proteomic approach in order to identify proteins undergoing S-nitrosylation. We provided evidence that cryptogein induced the S-nitrosylation of several proteins and identified 11 candidates, including CDC48 (cell division cycle 48), a member of the AAA+ ATPase (ATPase associated with various cellular activities) family. In vit…
La expansión geográfica de la renta del tabaco
2007
El monopolio real del tabaco fue decretado sólo para la Corona de Castilla en 1636. Debido a su reconocida eficacia, los gobernantes españoles intentaron implantarlo allá donde fuese políticamente posible. Después de la guerra de Sucesión, fue establecido en la Corona de Aragón, ya que estos territorios perdieron entonces su régimen foral de autonomía. Como las provincias vascas y Navarra consiguieron conservar su régimen foral, el Gobierno español no pudo someter allí el régimen general del estanco tabaquero y tuvo que contentarse con negociar soluciones que no perjudicasen al estanco general. Finalmente, en el contexto de las reformas borbónicas en América, la Renta del Tabaco fue gradual…
Questioning the role of salicylic acid and cytosolic acidification in mitogen-activated protein kinase activation induced by cryptogein in tobacco ce…
2001
Elicitors of plant defence reactions, oligogalacturonides and cryptogein, an elicitin produced by Phytophthora cryptogea, were previously shown to induce a rapid and transient activation of two mitogen-activated protein kinases (MAPKs) in cells of tobacco [ Nicotiana tabacum L. cv. Xanthi; A. Lebrun-Garcia et al. (1998) Plant J 15:773-781]. We verified that these two MAPKs correspond to the salicylic acid-induced protein kinase (SIPK) and the wound-induced protein kinase (WIPK). The involvement of salicylic acid (SA) in cryptogein-induced MAPK activation was investigated using transgenic NahG tobacco cells expressing the salicylate hydroxylase gene and thus unable to accumulate SA. The larg…
Nicotiana tabacum L. hloroplastu izmantošanas iespējas cilvēku cilmes šūnu barotņu bagātināšanai un cilmes šūnu proliferācijas un morfoloģisko izmaiņ…
2016
Lai izvērtētu izolētu tabakas hloroplastu potenciālu kā cilmes šūnu barotni bagātinošu līdzekli, FM-55-P cilvēka melanomas šūnas tika inkubētas 2 dienas ar izolētiem hloroplastiem, kas tika pievienoti šūnu kultūrai kā barotnes atšķaidījums vai kā hloroplastu piedeva. Tika noskaidrots, ka hloroplastu piedeva barotnei neizraisa ievērojamu proliferācijas samazinājumu salīdzinot ar barotnes atšķaidījumu un ka hloroplastu piedevas klātbūtnē melanocīti vairāk atraujas no kultūras virsmas bez šūnu nāves pazīmēm. Hloroplasti barotnē šķietami sadalījās un tika iekļauti melanocītu citoplazmā visos pievienošanas variantos. Izolētu hloroplastu ietekme uz melanomas šūnu kultūru tika vērtēta kā neizteikt…