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showing 10 items of 2807 documents

Impact of Midregional N‐Terminal Pro–Atrial Natriuretic Peptide and Soluble Suppression of Tumorigenicity 2 Levels on Heart Rhythm in Patients Treate…

2021

Background We assessed the impact of preprocedural plasma levels of MRproANP (midregional N‐terminal pro–atrial natriuretic peptide) and sST2 (soluble suppression of tumorigenicity 2) on recurrence of atrial fibrillation (AF) at 1 year after catheter ablation of AF. Methods and Results This was a prospective, multicenter, observational study including patients undergoing catheter ablation of AF. MRproANP and sST2 were measured in a peripheral venous blood preprocedure, and MRproANP was assessed in the right and left atrial blood during ablation. The primary end point was recurrent AF between 3 and 12 months postablation, defined as a documented (>30 seconds) episode of AF, flutter, or a…

Malemedicine.medical_specialtyTime Factorsmedicine.drug_classmedicine.medical_treatmentBiorhythmCatheter ablation030204 cardiovascular system & hematologyRisk Assessment03 medical and health sciences0302 clinical medicineHeart RatePredictive Value of TestsRecurrenceRisk FactorsInternal medicinecatheter ablationAtrial FibrillationmedicineNatriuretic peptideHumansIn patientArrhythmia and Electrophysiology030212 general & internal medicineHeart AtriaProspective StudiesOriginal ResearchAgedsST2business.industryMRproANPbiomarkersAtrial fibrillationPlasma levelsMiddle Agedmedicine.diseaseInterleukin-1 Receptor-Like 1 ProteinUp-RegulationHeart RhythmTreatment OutcomePro atrial natriuretic peptideCardiologyFemaleFranceCardiology and Cardiovascular MedicinebusinessCatheter Ablation and Implantable Cardioverter-DefibrillatorAtrial Natriuretic FactorJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
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Mortality after cardioverter-defibrillator replacement: Results of the DECODE survival score index

2020

Background Device replacement is the ideal time to reassess health care goals regarding continuing implantable cardioverter-defibrillator (ICD) therapy. Only few data are available on the decision making at this time. Objectives The goals of this study were to identify factors associated with poor prognosis at the time of ICD replacement and to develop a prognostic index able to stratify those patients at risk of dying early. Methods DEtect long-term COmplications after implantable cardioverter-DEfibrillator replacement (DECODE) was a prospective, single-arm, multicenter cohort study aimed at estimating long-term complications in a large population of patients who underwent ICD/cardiac resy…

Malemedicine.medical_specialtyTime Factorsmedicine.medical_treatmentPopulationReplacementCardiac resynchronization therapy030204 cardiovascular system & hematologyPrognostic indexImplantable cardioverter-defibrillatorNOElectrocardiography03 medical and health sciences0302 clinical medicineInterquartile rangePhysiology (medical)Internal medicinemedicineHumansProspective Studies030212 general & internal medicineeducationShared decision makingAgedOutcomeAged 80 and overHeart Failureeducation.field_of_studyIschemic cardiomyopathybusiness.industryProportional hazards modelMiddle AgedImplantable cardioverter-defibrillatorDefibrillators ImplantableSurvival RateDeath Sudden CardiacItalyFemaleCardiology and Cardiovascular MedicinebusinessDecision Making SharedBody mass indexFollow-Up StudiesCohort study
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D-dimer for risk stratification in haemodynamically stable patients with acute pulmonary embolism

2015

Patients with submassive pulmonary embolism (PE) have a higher short-term mortality than those with low-risk PE. Rapid identification of submassive PE is important for adequate treatment of non-massive PE. We aimed to investigate the utility of D-dimer for the prediction of submassive PE stadium in normotensive PE patients.Normotensive PE patients were classified into submassive or low-risk PE groups. In addition to the comparison of the groups, area under the curve (AUC) and D-dimer cut-off for the prediction of submassive PE stadium, multi-variate logistic regression for association between D-dimer values above this cut-off and submassive PE stadium were also calculated.The data of 129 no…

Malemedicine.medical_specialtyVentricular Dysfunction RightFibrin Fibrinogen Degradation ProductsTachycardiaInternal medicineHeart rateD-dimerHumansMedicineIn patientAgedRetrospective StudiesAged 80 and overbusiness.industryArea under the curveGeneral MedicineMiddle Agedmedicine.diseasePulmonary embolismLogistic ModelsBlood pressureHaemodynamically stableRisk stratificationCardiologyFemalePulmonary EmbolismbusinessAdvances in Medical Sciences
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Dietary intake of vitamin K is inversely associated with mortality risk

2014

Vitamin K has been related to cardiovascular disease and cancer risk. However, data on total mortality are scarce. The aimof the present study was to assess the association between the dietary intake of different types of vitamin K and mortality in a Mediterranean population at high cardiovascular disease risk. A prospective cohort analysis was conducted in 7216 participants from the PREDIMED (Prevención con Dieta Mediterránea) study (median follow-up of 4.8 y). Energy and nutrient intakes were evaluated using a validated 137-item food frequency questionnaire. Dietary vitamin K intake was calculated annually using the USDA food composition database and other published sources. Deaths were a…

Malemedicine.medical_specialtyVitamin KPopulationMedicine (miscellaneous)Diet MediterraneanLower riskNational Death IndexDIETA MEDITERRÀNIARisk FactorsNeoplasmsInternal medicineDiabetes mellitusVegetablesEstà en blancmedicineHumansPlant OilsProspective StudiesVITAMINES KProspective cohort studyeducationMALALTIES CARDIOVASCULARS / PREVENCIÓAgedProportional Hazards ModelsCiències de la salutAged 80 and overeducation.field_of_studyNutrition and DieteticsMediterranean RegionProportional hazards modelbusiness.industryIncidenceIncidence (epidemiology)ConfoundingHealth sciencesVitamin K 2Vitamin K 1Middle Agedmedicine.diseaseCiencias de la saludEndocrinologyDiabetes Mellitus Type 2Cardiovascular DiseasesFemalebusiness0022-3166Follow-Up Studies
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A collagen extraction and deuterium oxide stable isotope tracer method for the quantification of bone collagen synthesis rates in vivo.

2021

Abstract The development of safe and practical strategies to prevent weakening of bone tissue is vital, yet attempts to achieve this have been hindered by a lack of understanding of the short‐term (days‐weeks) physiology of bone collagen turnover. To address this, we have developed a method to quantify bone collagen synthesis in vivo, using deuterium oxide (D2O) tracer incorporation techniques combined with gas chromatography pyrolysis isotope‐ratio mass spectrometry (GC‐pyrolysis‐IRMS). Forty‐six male and female rats from a selectively bred model ingested D2O for 3 weeks. Femur diaphyses (FEM), tibia proximal (T‐PRO), and distal (T‐DIS) epiphyses‐metaphyses and tibia mid‐shaft diaphyses (T…

Malemedicine.medical_specialtybone turnoverPhysiologyluukollageenitstable isotopesbiomarkkeritRadiation-Protective Agents030204 cardiovascular system & hematologydeuterium oxideBone tissueGas Chromatography-Mass SpectrometryGC‐pyrolysis‐IRMSBone remodeling03 medical and health sciences0302 clinical medicineIn vivoPhysiology (medical)Internal medicineregeneraatio (biologia)medicineQP1-981AnimalsFemurTibiaFemurcollagen synthesisTibiaChemistryStable isotope ratioExtraction (chemistry)Original ArticlesRatsmedicine.anatomical_structureEndocrinologyDeuteriumGC-pyrolysis-IRMSisotooppianalyysiFemaleOriginal ArticleBone RemodelingCollagenluukudokset030217 neurology & neurosurgeryPyrolysisPhysiological reports
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Recanalization of occluded left main coronary artery in unstable angina pectoris

1984

Malemedicine.medical_specialtybusiness.industryUnstable anginaMiddle AgedCoronary Angiographymedicine.diseaseCoronary VesselsAngina Pectorismedicine.anatomical_structureInternal medicineCardiologyHumansMedicineAngina UnstableCardiology and Cardiovascular MedicinebusinessAngioplasty BalloonArteryThe American Journal of Cardiology
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Circulating adhesion molecules, matrix metalloproteinase-9, plasminogen activator inhibitor-1, and myeloperoxidase in coronary artery disease patient…

2010

There are many pathophysiological mechanisms underlying reciprocal relationships between changes in cytokines and insulin resistance in metabolic and cardiovascular disorders. The aim of this study was to evaluate alterations in soluble intercellular adhesion molecule-1 (sICAM-1), soluble vascular cell adhesion molecule-1 (sVCAM-1), soluble E-selectin (sE-selectin), matrix metalloproteinase-9 (MMP-9), plasminogen activator inhibitor-1 (PAI-1), and myeloperoxidase (MPO) levels, and their relation to insulin resistance in coronary artery disease (CAD) patients with stable and unstable angina (SAP, UAP).Non-diabetic CAD patients were classified into two groups: 22 patients with SAP and 22 pati…

Malemedicine.medical_specialtymedicine.medical_treatmentClinical BiochemistryCoronary Artery DiseaseBiochemistryAngina PectorisCoronary artery diseasechemistry.chemical_compoundInsulin resistanceInternal medicinePlasminogen Activator Inhibitor 1medicineHumansAgedPeroxidasebiologyCell adhesion moleculeUnstable anginabusiness.industryBiochemistry (medical)General MedicineMiddle Agedmedicine.diseaseEndocrinologyCytokineMatrix Metalloproteinase 9chemistryCase-Control StudiesMyeloperoxidasePlasminogen activator inhibitor-1biology.proteinFemaleInsulin ResistancebusinessCell Adhesion MoleculesPlasminogen activatorClinica Chimica Acta
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The Boundless World of Cranioplasty: A Multicenter Retrospective Study and Therapeutic Flow-Chart Patient-Specific Based.

2021

Background Cranioplasty is both a functional and aesthetical therapeutic option. In the clinical scenario every cranioplasty's material is potentially qualified to achieve the goal of calvarian reconstruction but there is a lack of agreement about the optimum choice, especially between the heterologous ones. The choice of cranioplasty widely depends on surgeon's personal preferences. In this retrospective multicentric study a comparative analysis of hydroxyapatite or titanium cranioplasties was carried on analyzing the main factors considered by the surgeon to choose a material rather than another one. Our results and data were compared with those reported in the scientific literature and a…

Malemedicine.medical_specialtymedicine.medical_treatmentMEDLINECranioplastyTherapeutic approachSexual and Gender MinoritiesPostoperative Complicationssynthetic cranioplastymedicineHumansIn patientReconstructive Surgical ProceduresHomosexuality MaleRetrospective StudiesDental ImplantsTitaniumSettore MED/27 - Neurochirurgiabusiness.industrySkullosteointegrationRetrospective cohort studyGeneral MedicinePatient specificPlastic Surgery Proceduresmost suitable material scoremedicine.diseaseCranioplastyComorbiditySurgeryOtorhinolaryngologyFlow chartSurgerybusinessThe Journal of craniofacial surgery
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Emergency angioplasty of totally occluded left main coronary artery in acute myocardial infarction and unstable angina pectoris--institutional experi…

1994

Acute occlusion of the left main coronary artery (LMCA) is a rare angiographic finding. We report five patients with acute myocardial infarction (AMI) and one patient with unstable angina, in whom reperfusion was achieved or attempted with percutaneous transluminal coronary angioplasty (PTCA). All patients had a long history of stable angina pectoris. The indication for emergency PTCA was cardiogenic shock in the five patients with MI. PTCA was successful in five of six patients. Three patients with reperfusion survived, three died. All survivors underwent coronary artery bypass grafting (CABG) and were still alive at 23 months, 3 and 8 years respectively in NYHA functional class II or III.…

Malemedicine.medical_specialtymedicine.medical_treatmentMyocardial InfarctionShock CardiogenicCollateral CirculationAnginaCoronary artery bypass surgeryReperfusion therapyLeft coronary arterymedicine.arteryInternal medicineAngioplastyCoronary CirculationmedicineHumanscardiovascular diseasesMyocardial infarctionAngina UnstableAngioplasty Balloon CoronaryCoronary Artery BypassAgedUnstable anginabusiness.industryMiddle Agedmedicine.diseaseSurgerysurgical procedures operativeTreatment OutcomeRight coronary arteryCardiologyFemaleEmergenciesCardiology and Cardiovascular MedicinebusinessFollow-Up StudiesEuropean heart journal
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Preoperative radiochemotherapy and radical surgery in comparison with radical surgery alone. A prospective, multicentric, randomized DÖSAK study of a…

1994

Abstract A multicentric, randomized study of squamous cell carcinoma (SCC) of the oral cavity and the oropharynx has been undertaken by DOSAK. The results after radical surgery alone have been compared with the results of combined preoperative radiochemotherapy followed by radical surgery. Patients with primary (biopsy proven) SCC of the oral cavity or the oropharynx with tumor nodes metastasis (TNM) stages T2–4, N0–3, M0 were included in the study. A total of 141 patients were treated by radical surgery alone, whereas 127 patients were treated by radical surgery preceded by preoperative radiochemotherapy. The preoperative treatment consisted of conventionally fractioned irradiation on the …

Malemedicine.medical_specialtymedicine.medical_treatmentlaw.inventionMetastasisRandomized controlled triallawPreoperative CareBiopsymedicineHumansLife TablesProspective StudiesRadical surgerySurvival analysisChemotherapymedicine.diagnostic_testbusiness.industryMiddle Agedmedicine.diseaseCombined Modality TherapySurgerySurvival RateRadiation therapyLog-rank testOropharyngeal NeoplasmsOtorhinolaryngologyLymphatic MetastasisCarcinoma Squamous CellFemaleMouth NeoplasmsSurgeryCisplatinNeoplasm Recurrence LocalOral SurgerybusinessFollow-Up StudiesInternational Journal of Oral and Maxillofacial Surgery
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