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showing 10 items of 2807 documents

Petrography and carbonate isotope stratigraphy from MIS AND-1B core, Antarctica: Evidence of the early Pliocene warming event

2011

Abstract A large portion of ANDRILL (ANtarctic geological DRILLing) core AND-1B recovered in the Western Ross Sea and spanning the early Pliocene has been investigated in order to obtain a detailed carbonate isotope record from Antarctic margin sediments through the early Pliocene warming event. Petrographic observations and mineralogical analyses reveal the authigenic nature of the carbonate and small proportions of Fe and Mg incorporated within the calcite lattice. High productivity conditions testified by ~ 80 m-thick diatomite interval (383 to 460 mbsf) well fit with the composite nature of the authigenic carbonate generally characterizing organic matter-rich sediments. As is known, sed…

ANDRILLCalciteGlobal and Planetary Changegeographygeography.geographical_feature_categoryδ13CStable isotope ratioδ18OGlacierAuthigenicearly PlioceneOceanographypalaeoclimatePetrographychemistry.chemical_compoundPaleontologychemistrystable isotopeAntarcticaCarbonateGeologyGlobal and Planetary Change
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Cabbage and fermented vegetables: from death rate heterogeneity in countries to candidates for mitigation strategies of severe COVID-19

2021

International audience; Large differences in COVID-19 death rates exist between countries and between regions of the same country. Some very low death rate countries such as Eastern Asia, Central Europe, or the Balkans have a common feature of eating large quantities of fermented foods. Although biases exist when examining ecological studies, fermented vegetables or cabbage have been associated with low death rates in European countries. SARS-CoV-2 binds to its receptor, the angiotensin-converting enzyme 2 (ACE2). As a result of SARS-CoV-2 binding, ACE2 downregulation enhances the angiotensin II receptor type 1 (AT1 R) axis associated with oxidative stress. This leads to insulin resistance …

ARIA groupAntioxidantMediterranean dietmedicine.medical_treatmentBrassicasulforaphaneMESH: Angiotensin-Converting Enzyme 2ReviewcabbageAntioxidants0302 clinical medicine10183 Swiss Institute of Allergy and Asthma ResearchVegetableskimchiFood sciencekimči0303 health sciencesMESH: NF-E2-Related Factor 23. Good healthAngiotensin-converting enzyme 22723 Immunology and Allergyfermentirana zelenjavaMESH: EcologyKeywords: Angiotensin converting enzyme 2NF-E2-Related Factor 2KEAP1-NRF2 SYSTEMImmunologyReviewsBrassicaNRF203 medical and health sciencesudc:578:635.34:663.15:COVID‐19angiotensin-converting enzyme 2CorrespondenceHumansMESH: SARS-CoV-2LactobacilluINTERMITTENT HYPOXIA2403 ImmunologyScience & TechnologyMESH: HumansAngiotensin II receptor type 1koronavirusMESH: Antioxidantsmedicine.disease030228 respiratory systemchemistryFermentationAllergymedicine.disease_causechemistry.chemical_compoundLINKING GUT MICROBIOTALactobacillalesLactobacillusImmunology and AllergyMESH: COVID-19Angiotensin converting enzyme 2030212 general & internal medicineOXIDATIVE STRESS[SDV.IMM.ALL]Life Sciences [q-bio]/Immunology/AllergologyKeywords: Angiotensin converting enzyme 2; COVID-19; Lactobacillus; cabbage; diet; fermented vegetable; kimchi; sulforaphane.angiotensin-converting enzyme 2; cabbage; COVID-19; diet; fermented vegetable; kimchi; Lactobacillus; sulforaphane2. Zero hungerFOODSEcologyLactobacillalesMortality rate10177 Dermatology ClinicMEDITERRANEAN DIET1107 ImmunologyLife Sciences & Biomedicinefermented vegetable610 Medicine & healthSettore MED/10 - Malattie Dell'Apparato RespiratorioBiologyMESH: FermentationMESH: Gastrointestinal MicrobiomeInsulin resistanceMESH: DietDownregulation and upregulationmedicine030304 developmental biologySARS-CoV-2COVID-19MESH: BrassicaCOVID-19; Lactobacillus; angiotensin-converting enzyme 2; cabbage; diet; fermented vegetable; kimchi; sulforaphane; Angiotensin-Converting Enzyme 2; Antioxidants; COVID-19; Diet; Ecology; Gastrointestinal Microbiome; Humans; Lactobacillales; NF-E2-Related Factor 2; Brassica; Fermentation; SARS-CoV-2; Vegetablesbiology.organism_classificationMESH: VegetablesDYSFUNCTIONDietGastrointestinal MicrobiomeLactobacillusMESH: Lactobacillalesangiotensin-converting enzyme 2 cabbage COVID-19 diet fermented vegetable kimchi Lactobacillus sulforaphanedietOxidative stressSulforaphane
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Partial substitution of fish meal with vegetable protein sources in a diet for sea bass: effects on lipogenesis

2005

Three isoproteic (49.4%) and isolipidic (17.0%) diets were prepared: A control diet FM, in which protein was derived from fish meal and two experimental diets in which 70% of the fish meal protein was substituted with wheat gluten meal (WGM) or wheat gluten meal plus soybean meal (WGMsb), respectively. The essential limiting amino acids were added to satisfy the requirements of the species (Tibaldi et al., 1996). Three hundred and fifteen sea bass (initial weight = 23.9±0. 1g )were randomly divided into nine homogenous groups. The animals were reared in a closed recirculation system at 23.9 ◦ C and were fed ad libitum twice a day for 96 days. The fish were weighed at the beginning and the e…

ATP citrate lyaseDicentrarchus labrax; Dietary Proteins; body lipid composition; adipositySoybean mealfish meal lipid composition lipid deposition sea bass vegetable proteinsBiologyGlucosephosphate DehydrogenasePlant Proteins DietaryFish mealMalate DehydrogenaseSettore BIO/10 - BiochimicaFish ProductsAnimalsSettore AGR/18 - Nutrizione E Alimentazione AnimaleDicentrarchus labraxFood scienceSea basschemistry.chemical_classificationMealadiposityGeneral VeterinaryBody WeightFatty acidGeneral MedicineLipid MetabolismAnimal Feedbody lipid compositionchemistryLiverLipogenesisATP Citrate (pro-S)-LyaseBody CompositionComposition (visual arts)BassDietary Proteins
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Clinical response to linaclotide at week 4 predicts sustained response in irritable bowel syndrome with constipation and improvements in digestive an…

2019

Background:Linaclotide is approved for the treatment of moderate-to-severe irritable bowel syndrome (IBS) with constipation (IBS-C) in adults. This study aimed to assess factors predictive of a clinical response and improvements in non-IBS symptoms with linaclotide treatment in a Spanish patient population.Methods:In this open-label phase IIIb study, patients with moderate-to-severe IBS-C received linaclotide 290 μg once daily for 12 weeks. The primary endpoint was clinical response at week 12, defined as >30% reduction in IBS symptom severity score (IBS-SSS) or IBS-SSS <75 plus self-reported response of feeling ‘better’ or ‘much better’ versus the baseline. Digestive nonintestinal an…

Abdominal painmedicine.medical_specialtyConstipation03 medical and health scienceschemistry.chemical_compound0302 clinical medicineInternal medicinefunctional gastrointestinal diseasesmedicinelcsh:RC799-869LinaclotideIrritable bowel syndromeOriginal Researchirritable bowel syndromebusiness.industryGastroenterologyabdominal painconstipationmedicine.diseasechemistry030220 oncology & carcinogenesisSustained response030211 gastroenterology & hepatologylcsh:Diseases of the digestive system. Gastroenterologymedicine.symptombusinessTherapeutic Advances in Gastroenterology
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NEW THERAPEUTIC PERSPECTIVES IN IRRITABLE BOWEL SYNDROME: TARGETING LOW-GRADE INFLAMMATION, IMMUNO-NEUROENDOCRINE AXIS, MOTILITY, SDECRETION AND BEYO…

2017

Irritable bowel syndrome (IBS) is a chronic, recurring, and remitting functional disorder of the gastrointestinal tract characterized by abdominal pain, distention, and changes in bowel habits. Although there are several drugs for IBS, effective and approved treatments for one or more of the symptoms for various IBS subtypes are needed. Improved understanding of pathophysiological mechanisms such as the role of impaired bile acid metabolism, neurohormonal regulation, immune, dysfunction, the epithelial barrier and the secretory properties of the gut has led to advancements in the treatment of IBS. With regards to therapies for restoring intestinal permeability, multiple studies with prebiot…

Abdominal painmedicine.medical_specialtyReviewFunctional disorderGastroenterologyPermeabilityBile Acids and Salts03 medical and health scienceschemistry.chemical_compound0302 clinical medicineGastrointestinal AgentsMesalazineInternal medicineImmunoendocrine axisTherapy; Low grade inflammation; Motility; Secretion; Irritable bowel syndrome; Immunoendocrine axismedicineHumansSecretionIrritable bowel syndromeInflammationClinical Trials as TopicGastrointestinal agentSettore MED/12 - GastroenterologiaLow grade inflammationIntestinal permeabilitybusiness.industryGastroenterologyMotilityDrugs InvestigationalGeneral Medicinemedicine.diseaseAbdominal PainRifaximinIntestinesClinical trialIrritable bowel syndromeSettore MED/18 - Chirurgia GeneraleTreatment Outcomechemistry030220 oncology & carcinogenesis030211 gastroenterology & hepatologyTherapymedicine.symptomGastrointestinal Motilitybusiness
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An Arakelov inequality in characteristic p and upper bound of p-rank zero locus

2008

In this paper we show an Arakelov inequality for semi-stable families of algebraic curves of genus $g\geq 1$ over characteristic $p$ with nontrivial Kodaira-Spencer maps. We apply this inequality to obtain an upper bound of the number of algebraic curves of $p-$rank zero in a semi-stable family over characteristic $p$ with nontrivial Kodaira-Spencer map in terms of the genus of a general closed fiber, the genus of the base curve and the number of singular fibres. An extension of the above results to smooth families of Abelian varieties over $k$ with $W_2$-lifting assumption is also included.

Abelian varietyAlgebra and Number TheoryStable curveCombinatoricsAlgebraic cycleMathematics - Algebraic GeometryMathematics::Algebraic Geometry14D05 (Primary) 14G25 14H10 (Secondary)Algebraic surfaceFOS: MathematicsGenus fieldAlgebraic curveAbelian groupAlgebraic Geometry (math.AG)Singular point of an algebraic varietyMathematicsJournal of Number Theory
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Carbon and nitrogen stable isotope ratios of soils and grasses as indicators of soil characteristics and biological taxa

2019

Abstract The use of stable isotope techniques can assist in understanding interactions of plants with various abiotic and biotic processes. In the research, we focused on carbon (C) and nitrogen (N) isotopes because they are the most important resources influencing plant function and the biogeochemical cycles. The 13C/12C and 15N/14N ratios in plants and in soils and the relationships between these ratios and biological and environmental factors of widely distributed native C3 plants (couch grass, plantain and yarrow) collected from two sites in St. Petersburg, Russia were studied. The soil characteristics of the sites were rather different. This had a significant effect on the isotope rati…

Abiotic componentBiogeochemical cycleIsotopeSoil textureStable isotope ratiochemistry.chemical_element010501 environmental sciences010502 geochemistry & geophysics01 natural sciencesPollutionNitrogenAgronomychemistryGeochemistry and PetrologySoil waterEnvironmental ChemistryEnvironmental scienceCarbon0105 earth and related environmental sciencesApplied Geochemistry
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Sr-isotope analysis of speleothems by LA-MC-ICP-MS: High temporal resolution and fast data acquisition

2017

Speleothems are well established climate archives. A wide array of geochemical proxies, including stable isotopes and trace elements are present within speleothems to reconstruct past climate variability. However, each proxy is influenced by multiple factors, often hampering robust interpretation. Sr isotope ratios (87Sr/86Sr) can provide useful information about water residence time and water mixing in the host rock, as they are not fractionated during calcite precipitation. Laser ablation multi-collector-inductively coupled plasma mass spectrometry (LA-MC-ICP-MS) has rarely been used for determination of Sr isotope signatures in speleothems, as speleothems often do not possess appropriate…

Ablation TechniquesSpeleothemMineralogyF700F800F600010502 geochemistry & geophysics01 natural sciencesF900chemistry.chemical_compoundGeochemistry and Petrology0105 earth and related environmental sciencesIsotope analysisCalcitegeographygeography.geographical_feature_categoryLaser ablationIsotopeStable isotope ratio010401 analytical chemistryGeology0104 chemical scienceschemistry13. Climate actionCarbonateGeology
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Ag11(SG)7 : A New Cluster Identified by Mass Spectrometry and Optical Spectroscopy

2014

We report a one-step and high yield synthesis of a red-luminescent silver cluster with the molecular formula, Ag11(SG)7 (SG: glutathionate) via reduction of silver ions by sodium borohydride in the presence of the tripeptide, glutathione (GSH). The as-prepared cluster shows prominent absorption features at 485 and 625 nm in its UV-vis absorption spectrum. Aging of the as-prepared cluster solution led to the disappearance of the 625 nm peak, followed by broadening of the 485 nm peak to give three maxima at ?487, 437, and 393 nm in its absorption spectrum. These peaks remain unchanged even after polyacrylamide gel electrophoresis (PAGE), where a single band was observed confirming high purity…

Absorption spectroscopyta114Electrospray ionizationAnalytical chemistryMass spectrometryAbsorption spectra; Density functional theory; Electrodeposition; Electromagnetic wave absorption; Electrophoresis; Electrospray ionization; Isotopes; Light absorption; Mass spectrometry; Metal ions; Potable water; Spectrometry; Ultraviolet spectroscopy; Absorption features; Electrospray ionization mass spectrometry; High yield synthesis; Molecular formula; Optical spectroscopy; Polyacrylamide gel electrophoresis; Sodium boro hydrides; UV-VIS absorption spectra; Absorption spectroscopySurfaces Coatings and FilmsElectronic Optical and Magnetic MaterialsIonSodium borohydridechemistry.chemical_compoundGeneral EnergyUltraviolet visible spectroscopychemistryPhysical and Theoretical ChemistryAbsorption (electromagnetic radiation)Spectroscopyta116Journal of Physical Chemistry C
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Claridad y calidad de las notas explicativas en estados financieros bajo IFRS. Un estudio de brechas de Expectativas Gaps para normas contables (NIC …

2018

Este análisis situacional de la claridad y calidad de las notas explicativas en los estados financieros bajo IFRS (Obligatory Disclosure), pretende entregar claridad acerca de la calidad de la información entregada en las notas explicativas para 4 normas de Información Contable, claves en la información financiera en los países de la región, que son la NIC 2; Notas referente a Inventarios, NIC 16; Notas referente a Propiedad Planta y Equipos, NIC 37; Notas referente a Provisiones, y NIC 38; Notas referente a Activos Intangibles. Adicionalmente, este trabajo estudia la brecha de expectativas (Expectation Gaps) que existe en la información entregada en las notas de los estados financieros par…

Accounting. Bookkeepingnotas explicativas a los estados financierosHF5601-5689HG1-9999explanatory notes to the financial statementsbrecha de expectativasGeneral MedicineSituational accounting analysisFinanceexpectations gapanálisis situacional contableQuipukamayoc
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