Search results for "tce"
showing 10 items of 43 documents
Somatosensory Brain Function and Gray Matter Regional Volumes Differ According to Exercise History : Evidence from Monozygotic Twins
2017
Associations between long-term physical activity and cortical function and brain structure are poorly known. Our aim was to assess whether brain functional and/or structural modulation associated with long-term physical activity is detectable using a discordant monozygotic male twin pair design. Nine monozygotic male twin pairs were carefully selected for an intrapair difference in their leisure-time physical activity of at least three years duration (mean age 34 ± 1 years). We registered somatosensory mismatch response (SMMR) in EEG to electrical stimulation of fingers and whole brain MR images. We obtained exercise history and measured physical fitness and body composition. Equivalent ele…
Vidzemes muižu zemnieku sociālekonomiskais portrets 19.gs. pirmajā pusē: Lielvārdes muižas piemērs
2022
Bakalaura darba “Vidzemes muižu zemnieku sociālekonomiskais portrets 19. gs. pirmajā pusē: Lielvārdes muižas piemērs” mērķis ir analizēt 19. gadsimta pirmās puses sociālekonomisko un politisko norišu ietekmi uz Vidzemes zemnieku dzīves apstākļiem, par piemēru ņemot Lielvārdes privātmuižu. Darba ietvaros tiek analizēti 18. gadsimta un 19. gadsimta pirmās puses notikumi (zemnieku nemieri, Napoleona kari), Vidzemes muižniecība, tās izdotie likumi, kā arī informācija par Lielvārdes muižas zemniekiem šajā laikā. Darba rezultātā papildināta informācija par šo samērā maz pētīto muižu un analizēti dažādo notikumu, it īpaši dzimtbūšanas atcelšanas, ietekme uz zemnieku stāvokli īstermiņā.
No brihwestibas un wiņņas eezelschanas Kursemmē: wisseem gohdigeem Kursemmes arrajeem par pamahzischanu un wajadsigu siņņu
1819
Grāmatas titullapā autors: Launitz, Krischan Wridrik
Asymmetry in the human primary somatosensory cortex and handedness.
2003
Brain asymmetry is a phenomenon well known for handedness and language specialization and has also been studied in motor cortex. Less is known about hemispheric asymmetries in the somatosensory cortex. In the present study, we systematically investigated the representation of somatosensory function analyzing early subcortical and cortical somatosensory-evoked potentials (SEP) after electrical stimulation of the right and left median nerve. In 16 subjects, we compared thresholds, the peripheral neurogram at Erb point, and, using MRI-based EEG source analysis, the P14 brainstem component as well as N20 and P22, the earliest cortical responses from the primary sensorimotor cortex. Handedness w…
Cutaneous Painful Laser Stimuli Evoke Responses Recorded Directly From Primary Somatosensory Cortex in Awake Humans
2004
Negative and positive laser evoked potential (LEP) peaks (N2*, P2**) were simultaneously recorded from the primary somatosensory (SI), parasylvian, and medial frontal (MF: anterior cingulate and supplementary motor area) cortical surfaces through subdural electrodes implanted for the surgical treatment of intractable epilepsy. Distribution of the LEP N2*and P2**peaks was estimated to be in cortical areas (SI, parasylvian, and MF) identified by anatomic criteria, by their response to innocuous vibratory stimulation of a finger (v-SEP), and to electrical stimulation of the median nerve (e-SEP). The maximum of the LEP N2*peak was located on the CS, medial (dorsal) to the finger motor area, as …
No brihwestibas un wiņņas eezelschanas Kursemmē : Wisseem gohdigeem Kursemmes arrajeem par pamahzischanu un wajadsigu siņņu [No brīvestības un viņas …
1819
Tekstā arī “Dziesma uz Ķeizara Aleksandra dzimšanas dienu”, dziesma “No brīvestības”, Kurzemes arāja īsu lūgšana priekš dabūtās brīvestības
Circulating specific antibodies enhance systemic cross-priming by delivery of complexed antigen to dendritic cells in vivo
2012
Increasing evidence suggests that antibodies can have stimulatory effects on T-cell immunity. However, the contribution of circulating antigen-specific antibodies on MHC class I cross-priming in vivo has not been conclusively established. Here, we defined the role of circulating antibodies in cross-presentation of antigen to CD8(+) T cells. Mice with hapten-specific circulating antibodies, but naϊve for the T-cell antigen, were infused with haptenated antigen and CD8(+) T-cell induction was measured. Mice with circulating hapten-specific antibodies showed significantly enhanced cross-presentation of the injected antigen compared with mice that lacked these antibodies. The enhanced cross-pre…
Exacerbated experimental autoimmune encephalomyelitis in mast-cell-deficient KitW-sh/W-sh mice
2011
Mast cell (MC)-deficient c-Kit mutant Kit(W/W-v) mice are protected against experimental autoimmune encephalomyelitis (EAE), an animal model of multiple sclerosis, suggesting a detrimental role for MCs in this disease. To further investigate the role of MCs in EAE, we took advantage of a recently characterized model of MC deficiency, Kit(W-sh/W-sh). Surprisingly, we observed that myelin oligodendrocyte glycoprotein (MOG)(35-55)-induced chronic EAE was exacerbated in Kit(W-sh/W-sh) compared with Kit(+/+) mice. Kit(W-sh/W-sh) mice showed more inflammatory foci in the central nervous system (CNS) and increased T-cell response against myelin. To understand whether the discrepant results obtaine…
Detailed characterization of human Mycobacterium tuberculosis specific HLA-E restricted CD8+TÂ cells
2018
HLA-E presented antigens are interesting targets for vaccination given HLA-Esâ essentially monomorphic nature. We have shown previously that Mycobacterium tuberculosis (Mtb) peptides are presented by HLA-E to CD8+effector TÂ cells, but the precise phenotype and functional capacity of these cells remains poorly characterized. We have developed and utilized in this study a new protocol combining HLA-E tetramer with intracellular staining for cytokines, transcription factors and cytotoxic molecules to characterize these cells in depth. We confirm in this study the significantly increased ex vivo frequency of Mtb-peptide/HLA-E-TM+CD8+TÂ cells in the circulation of patients with active tubercu…
Les loisirs sportifs en milieu de grande industrie : sport, patronat et organisations ouvrières au Creusot et à Montceau-les-Mines (1879-1939).
2009
This study describes the origin and development of the sports phenomenon in the industrial cities of Le Creusot and Montceaules-Mines (Saône-et-Loire, Burgundy), from 1879 to 1939. Throughout this period, sports in Le Creusot were totally dominated by associations led and controlled by the manufacturers, whereas in Montceau-les-Mines, worker sports were the object of conflict between industrialists and labor organisations. Such a contrast signals the existence of tight connections at the local level between the history of a place and the way in which a sport develops there. At the same time, these observations suggest some conclusions about historical conditions necessary to the emergence o…