Search results for "teeri"

showing 10 items of 308 documents

Ultrafast structural changes within a photosynthetic reaction centre

2021

Nature <London> / Physical science 589, 310 - 314 (2021). doi:10.1038/s41586-020-3000-7

0301 basic medicinePhotosynthetic reaction centreChlorophyllModels MolecularklorofylliCytoplasmUbiquinonePhotosynthetic Reaction Center Complex ProteinsElectrons02 engineering and technologyPhotochemistrymedicine.disease_cause530yhteyttäminenbakteeritElectron Transport03 medical and health sciencesElectron transfermedicineMoleculeddc:530BacteriochlorophyllsbioenergetiikkaComputingMilieux_MISCELLANEOUSHyphomicrobiaceaeMultidisciplinaryBinding SitesCrystallography[SDV.BBM.BS]Life Sciences [q-bio]/Biochemistry Molecular Biology/Structural Biology [q-bio.BM]ChemistryBlastochloris viridisLaserskalvot (biologia)PheophytinsBiological membraneVitamin K 2021001 nanoscience & nanotechnologyAcceptor030104 developmental biologyPicosecondFemtosecondsense organsProtons0210 nano-technologyOxidation-Reductionröntgenkristallografia
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Long-term genomic coevolution of host-parasite interaction in the natural environment

2017

Antagonistic coevolution of parasite infectivity and host resistance may alter the biological functionality of species, yet these dynamics in nature are still poorly understood. Here we show the molecular details of a long-term phage–bacterium arms race in the environment. Bacteria (Flavobacterium columnare) are generally resistant to phages from the past and susceptible to phages isolated in years after bacterial isolation. Bacterial resistance selects for increased phage infectivity and host range, which is also associated with expansion of phage genome size. We identified two CRISPR loci in the bacterial host: a type II-C locus and a type VI-B locus. While maintaining a core set of conse…

0301 basic medicineTime Factorsmedicine.medical_treatmentvirusesGeneral Physics and AstronomyGenomeCRISPR SpacersbakteeritBacteriophageEnvironmental MicrobiologyCRISPRBacteriophagesClustered Regularly Interspaced Short Palindromic RepeatsANTAGONISTIC COEVOLUTIONADAPTATIONbacteriaInfectivityGenetics0303 health scienceseducation.field_of_studyMultidisciplinaryQgenomiikkaBACTERIOPHAGE RESISTANCE MECHANISMSresistance (medicine)bacteriophagesPhage therapyScienceAntagonistic Coevolution030106 microbiologyPopulationevoluutioVirulencePHAGELocus (genetics)Genome ViralBiologyFlavobacteriumArticlebakteriofagitGeneral Biochemistry Genetics and Molecular BiologyHost-Parasite InteractionsEvolution Molecular03 medical and health sciencesCRISPR-CAS SYSTEMSFISHevolutionmedicinegenomicseducationGenome size1172 Environmental sciences030304 developmental biology030306 microbiologyGeneral Chemistrybiology.organism_classificationEVOLUTIONresistenssiPATHOGEN FLAVOBACTERIUM-COLUMNARE030104 developmental biologyMutationCRISPR LociVIRULENCEIMMUNE-SYSTEMGenome BacterialNature Communications
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Sympatric Ixodes-tick species: pattern of distribution and pathogen transmission within wild rodent populations

2018

AbstractThe generalist tick Ixodes ricinus is the most important vector for tick-borne pathogens (TBP), including Borrelia burgdorferi sensu lato, in Europe. However, the involvement of other sympatric Ixodes ticks, such as the specialist vole tick I. trianguliceps, in the enzootic circulations of TBP remains unclear. We studied the distribution of I. ricinus and I. trianguliceps in Central Finland and estimated the TBP infection likelihood in the most common rodent host in relation with the abundance of the two tick species. Ixodes trianguliceps was encountered in all 16 study sites whereas I. ricinus was frequently observed only at a quarter of the study sites. The abundance of I. ricinus…

0301 basic medicineanimal diseaseslcsh:MedicineDisease VectorspuutiaisetBORRELIA-BURGDORFERI0302 clinical medicinepopulaatiotSCAPULARIS ACARIpathogen transmissionlcsh:ScienceFinlandMultidisciplinarybiologyArvicolinaeRicinuslevinneisyysBORNE ENCEPHALITIS-VIRUSSympatrytaudinaiheuttajatTick-Borne DiseasesANAPLASMA-PHAGOCYTOPHILUMEnzooticIxodes ricinusjyrsijät030231 tropical medicineZoologyLYME BORRELIOSISTickTRIANGULICEPSArticle03 medical and health sciencesIxodes triangulicepsparasitic diseasesAnimalsHumansBorrelia burgdorferiIxodesBABESIA-MICROTILAND-USELANDSCAPEfungilcsh:Rbiology.organism_classificationbacterial infections and mycosesBorrelia-bakteerit030104 developmental biologyRICINUS TICKSVoleIxodeslcsh:Q3111 BiomedicineScientific Reports
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Extending the hosts of Tectiviridae into four additional genera of Gram-positive bacteria and more diverse Bacillus species

2017

Abstract Tectiviridae are composed of tailless bacteriophages with an icosahedral capsid and an inner membrane enclosing a double-stranded 15 kb linear DNA genome. Five of the seven previously studied Tectivirus isolates infect bacteria from Bacillus cereus sensu lato group (Betatectivirus), one distantly related member (PRD1) infect Enterobactericeae (Alpatectivirus) and one recently discovered virus infect Gluconobacter cerinus (Gammatectivirus). Here we expand the host spectrum of Betatectivirus elements to four additional genera (Streptococcus, Exiguobacterium, Clostridium and Brevibacillus) and to more distantly related Bacillus species (B. pumilus and B. flexus) by studying the genome…

0301 basic medicinebacteriophagesprophageevoluutioBacillusBacillusGenome ViralGram-Positive BacteriaBacillus-bakteeritGenomeHost SpecificitybakteriofagitbakteeritBacteriophage03 medical and health sciencesVirologyevolutionbacteriaPhylogenyProphageSyntenyGeneticsbiologyta1183fungita1182TectivirusTectivirusSequence Analysis DNAbiology.organism_classificationExiguobacterium030104 developmental biologyDNA ViralTectiviridaeTectiviridaeVirology
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Enrichment of Bacterioplankton Able to Utilize One-Carbon and Methylated Compounds in the Coastal Pacific Ocean

2018

International audience; Understanding the temporal variations and succession of bacterial communities involved in the turnover of one-carbon and methylated compounds is necessary to better predict bacterial impacts on the marine carbon cycle and air-sea carbon fluxes. The ability of the local bacterioplankton community to exploit one-carbon and methylated compounds as main source of bioavailable carbon during a productive and less productive period was assessed through enrichment experiments. Surface seawater was amended with methanol and trimethylamine-N-oxide (TMAO), and bacterial abundance, production, oxygen consumption, as well as methanol turnover and growth rates of putative methylot…

0301 basic medicinelcsh:QH1-199.5010504 meteorology & atmospheric sciencesta1172rannikkoalueetOcean EngineeringTMAOlcsh:General. Including nature conservation geographical distributioncoastal ecosysAquatic ScienceBacterial growthOceanography01 natural sciencesOceanospirillalesbakteeritCarbon cycleekosysteemit03 medical and health sciencesMethylophagabacterial community compositionC114. Life underwaterlcsh:Science[SDU.STU.OC]Sciences of the Universe [physics]/Earth Sciences/Oceanography0105 earth and related environmental sciencesWater Science and TechnologymethanolGlobal and Planetary ChangeFacultativeMethanol dehydrogenasebiologyChemistryplanktonBacterioplanktonbiology.organism_classificationmetanoliekosysteemit (ekologia)030104 developmental biology[SDV.MP]Life Sciences [q-bio]/Microbiology and Parasitology13. Climate actionEnvironmental chemistrycoastal ecosystemlcsh:QSeawatermxaF
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Minor environmental concentrations of antibiotics can modify bacterial virulence in co-infection with a non-targeted parasite.

2018

Leakage of medical residues into the environment can significantly impact natural communities. For example, antibiotic contamination from agriculture and aquaculture can directly influence targeted pathogens, but also other non-targeted taxa of commensals and parasites that regularly co-occur and co-infect the same host. Consequently, antibiotics could significantly alter interspecific interactions and epidemiology of the co-infecting parasite community. We studied how minor environmental concentrations of antibiotic affects the co-infection of two parasites, the bacterium Flavobacterium columnare and the fluke Diplostomum pseudospathaceum , in their fish host. We found that antibiotic in …

0301 basic medicinemedicine.drug_classAntibioticsVirulenceOxytetracyclineAquacultureTrematode InfectionsinfektiotFlavobacteriumantibioticsMicrobiologybakteerit03 medical and health sciencesFish DiseasesAntibiotic resistanceco-infectionAquacultureFlavobacteriaceae InfectionsloisetDrug Resistance BacterialmedicineWater Pollution ChemicalParasite hostingAnimalsbacteriabiologyVirulencebusiness.industryCoinfectionimumadotta1183antibiootitvirulenssiCommensalismbiology.organism_classificationAgricultural and Biological Sciences (miscellaneous)Anti-Bacterial Agents030104 developmental biology13. Climate actionympäristövaikutuksetOncorhynchus mykissFlavobacterium columnareparasiteta1181TrematodaGeneral Agricultural and Biological SciencesbusinessPathogen BiologyBacteriaBiology letters
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The forgotten tale of Brazilian phage therapy

2020

The use of bacteriophages to treat bacterial infections (known as phage therapy) is considered a possible solution to the antimicrobial resistance crisis. However, phage therapy is not a new concept. The discovery of phages in the early 20th century was closely tied to clinical practice, and phage therapy quickly spread around the world. The use of phage therapy in South America in the previous century is still shrouded in mystery and has been mentioned only briefly in recent scientific literature. Research on Brazilian reference collections of medical texts showed that Brazil was an important, but so far little-known, player of phage therapy, uncovering interesting priority claims and miss…

0301 basic medicinemedicine.medical_specialtybacteriophagesphage therapybakteeritauditHistoryPhage therapyvirusesmedicine.medical_treatment030106 microbiologyStaphylococcal infectionsbakteriofagit03 medical and health sciencesAntibiotic resistanceoppihistoriamedicineHumansBacteriophagesPhage TherapytutkimushistoriaBacillary dysenteryBacterial Infectionsmedicine.diseasefagiterapiaClinical Practice030104 developmental biologyInfectious Diseasesbacterial infectionsFamily medicineBrasiliaBrazilThe Lancet Infectious Diseases
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Native arbuscular mycorrhizal symbiosis alters foliar bacterial community composition.

2017

The effects of arbuscular mycorrhizal (AM) fungi on plant-associated microbes are poorly known. We tested the hypothesis that colonization by an AM fungus affects microbial species richness and microbial community composition of host plant tissues. We grew the grass, Deschampsia flexuosa in a greenhouse with or without the native AM fungus, Claroideoglomus etunicatum. We divided clonally produced tillers into two parts: one inoculated with AM fungus spores and one without AM fungus inoculation (non-mycorrhizal, NM). We characterized bacterial (16S rRNA gene) and fungal communities (internal transcribed spacer region) in surface-sterilized leaf and root plant compartments. AM fungus inoculat…

0301 basic medicineplant-associated microbesarbuscular mycorrhizal fungiPlant ScienceFungusBiologyPoaceaebakteerit03 medical and health sciencesMycorrhizaeBotanyGeneticsmykorritsasienetColonizationGlomeromycotaSymbiosisMolecular BiologyEcology Evolution Behavior and SystematicsFinland2. Zero hungerBacteriaInoculationMicrobiotafungiBacteroidetesfood and beverageshigh-throughput sequencingGeneral Medicinefoliar nitrogen15. Life on landbiology.organism_classificationSporePlant Leaves030104 developmental biologyMicrobial population biologyDeschampsia flexuosaProteobacteriaMycorrhiza
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Monitoring of ticks and tick-borne pathogens through a nationwide research station network in Finland.

2020

In 2015 a long-term, nationwide tick and tick-borne pathogen (TBP) monitoring project was started by the Finnish Tick Project and the Finnish Research Station network (RESTAT), with the goal of producing temporally and geographically extensive data regarding exophilic ticks in Finland. In the current study, we present results from the first four years of this collaboration. Ticks were collected by cloth dragging from 11 research stations across Finland in May September 2015-2018 (2012-2018 in Seili). Collected ticks were screened for twelve different pathogens by qPCR: Borrelia afzelii, Borrelia garinii, Borrelia valaisiana, Borrelia burgdorferi sensu stricto, Borrelia miyamotoi, Babesia sp…

0301 basic medicineviruksetPopulation DynamicsmonitorointiIxodes persulcatuspuutiaisetACARImedicine.disease_causeBURGDORFERI SENSU-LATODISEASEbakteeritTicks0302 clinical medicineINFECTIONPOPULATIONFinland11832 Microbiology and virologyTick-borne pathogensbiologylongitudinal studylevinneisyysPREVALENCEInfectious Diseasestaudinaiheuttajat1181 Ecology evolutionary biologyEpidemiological Monitoringtick-borne pathogensBartonella-bakteeritSeasonsLongitudinal studyNymphIxodes ricinusMonitoringBorrelia valaisiana030231 tropical medicineZoologyBabesiaLYME BORRELIOSISBorrelia miyamotoipitkittäistutkimusTickBorrelia afzeliiMicrobiologyticksEncephalitis Viruses Tick-Borne03 medical and health sciencesCOINFECTIONSparasitic diseasesGram-Negative BacteriamedicineAnimalsBorrelia burgdorferiIxodesIXODES-RICINUS TICKSbiology.organism_classificationbacterial infections and mycosespunkitBorrelia-bakteeritmonitoring030104 developmental biologyNationwideitiöeläimetInsect ScienceParasitologyBorrelia gariniinationwideCANDIDATUS NEOEHRLICHIA MIKURENSISTicks and tick-borne diseases
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Higher resource level promotes virulence in an environmentally transmitted bacterial fish pathogen

2017

Diseases have become a primary constraint to sustainable aquaculture, but remarkably little attention has been paid to a broad class of pathogens: the opportunists. Opportunists often persist in the environment outside the host, and their pathogenic features are influenced by changes in the environment. To test how environmental nutrient levels influence virulence, we used strains of Flavobacterium columnare, an environmentally transmitted fish pathogen, to infect rainbow trout and zebra fish in two different nutrient concentrations. To separate the effects of dose and nutrients, we used three infective doses and studied the growth of bacteria in vitro. High nutrient concentration promoted …

0301 basic medicineympäristöVirulenceVirulence factorMicrobiologybakteerit03 medical and health sciencesNutrientAquacultureGenetics14. Life underwaterbacteriaPathogenvesiviljely (kalatalous)Ecology Evolution Behavior and Systematics2. Zero hungerbiologybusiness.industryHost (biology)infection nutrientnutrientvirulenssiOriginal Articlesbiology.organism_classificationinfectionvirulence030104 developmental biologyaquacultureFlavobacterium columnareta1181Original ArticleGeneral Agricultural and Biological SciencesbusinessenvironmentBacteriaEvolutionary Applications
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