Search results for "temi"
showing 10 items of 3194 documents
New Capabilities of the FLUKA Multi-Purpose Code
2022
We would like to deeply thank the CERN Knowledge Transfer and Legal Service teams for their essential and extended support. Our appreciation also goes to the FLUKA.CERN Collaboration Board members for their strong commitment.
IMPIANTO DI STABILIZZAZIONE DI UNA IMBARCAZIONE A SOSTENTAMENTO ALARE
2012
Lo studio, frutto dell’attività di ricerca svolta dal DICGIM dell’Università degli Studi di Palermo in partnership con l’Engineering Department della Ustica Lines S.p.A. nell’ambito di un progetto finanziato con fondi PON Ricerca e Competitività 2007-2013, analizza preliminarmente le cause di guasto comportanti la fermata di un battello a sostentamento alare HSC per trasporto passeggeri al fine di individuare i componenti critici del mezzo. Individuato tale componente nel sistema di stabilizzazione, viene valutato l’impatto economico che il fermo del battello comporta sui costi operativi della Compagnia di navigazione. L’entità di tali costi, anche in termini di mancata utilizzazione del me…
PROGETTAZIONE DI UN MECCANISMO DI MOVIMENTAZIONE DEI FLAPS DI UN ALISCAFO
2012
Lo studio, frutto dell’attività di ricerca svolta dal DICGIM dell’Università degli Studi di Palermo in partnership con l’Engineering Department della Ustica Lines S.p.A. nell’ambito di un progetto finanziato con fondi PON Ricerca e Competitività 2007-2013, analizza preliminarmente le cause di guasto comportanti la fermata di un aliscafo HSC per trasporto passeggeri al fine di individuare i componenti critici del mezzo. Individuato tale criticità nel sistema di stabilizzazione, viene valutato l’impatto economico del fermo del battello sui costi operativi della Compagnia di navigazione. L’entità di tali costi, anche in termini di mancata utilizzazione del mezzo, comporta la necessità di un ap…
Rainwater draining in historical buildings: local specificities and techniques
2013
Se trattati e manuali descrivono compiutamente la "regola dell'arte" riferita ai sistemi costruttivi di maggiore diffusione, il più delle volte riconoscibili in ambiti sovranazionali e nelle architetture di maggiore livello, così non è per quelle soluzioni tecniche tipiche di periodi storici ed aree limitate, importanti nella formazione dell'identità del luogo, la cui conoscenza è legata ad una tradizione effimera raramente oggetto di analisi, di attenzione e di valorizzazione. In questa sede si fa riferimento ai sistemi per il convogliamento o l’allontanamento dell’acqua piovana dagli edifici, in cui lo studio dell’architettura storica fornisce una vasta gamma di casi in cui la tecnologia …
E-Fairs: a Cyber-Physical System for Aggregation and Economy of Scale in e-Commerce
2018
In recent years, the e-commerce arena has deeply changed because of the advent of new business models and the growing weight of huge global actors like Amazon. Some business models create competition between users, and the product price tends to rise (e.g., online auctions); other models, including group-buying, make users cooperate, and the price tends to go down. The present study extends the group-buying model and proposes a cyber-physical system called e-fair, in which both sellers and buyers are grouped to negotiate on a specific product or service. E-fairs minimize the global purchase price and the shipping resources respectively with the aggregation of demand and supply as well as or…
Optical biosensor-based characterization of anti-double-stranded DNA monoclonal antibodies as possible new standards for laboratory tests.
2009
The serum determination of circulating anti-double-stranded (ds)DNA autoantibodies is a routine measure for the laboratory diagnosis of systemic lupus erythematosus. Since available assays differ substantially and no feasible calibrator is available, the aim of this study was to evaluate a recently introduced surface plasmon resonance (SPR) biosensor chip for binding studies between dsDNA and anti-dsDNA autoantibodies and to demonstrate its usefulness for the characterization of new monoclonal antibody (mAb) standards and standardization of assays. We characterized two human and one murine monoclonal anti-dsDNA antibodies by measuring the kinetic on- and off-rates using the biosensor and ca…
Dynamic 4D Blood Flow Representation in the Aorta and Analysis from Cine-MRI in Patients
2007
International audience; Abstract: Natural evolution of aortic disease is characterized by a diameter increase that can result in aortic dissection or rupture. Currently the evaluation of risk of rupture or dissection is based on the size of the aorta. However, this parameter is not always relevant and it appears necessary to define new parameters. In this perspective, 3D velocity imaging acquired with ECG gated velocity-encoded cine-MRI allows the aortic blood flow study. As the acquired images are not directly usable, the present study proposes a 4D-representation Of aortic blood flow in order to optimize the visualization of the particularities of non-laminar flow within the aorta. Image …
Sunlight exposure exerts immunomodulatory effects to reduce multiple sclerosis severity
2021
AbstractBackgroundMultiple sclerosis (MS) disease risk is associated with reduced sun exposure. This study assessed the relationship between measures of sun-exposure (vitamin D (vitD), latitude) and MS disease severity, the mechanisms of action, and effect-modification by medication and sun-sensitivity associated MC1R variants.MethodsTwo multi-center cohort studies (nNationMS=946, nBIONAT=991). Outcomes were the multiple sclerosis severity score (MSSS) and the number of Gd-enhancing lesion (GELs). RNAseq of four immune cell populations before and after UV-phototherapy of five MS patients.ResultsHigh serum vitD was associated with reduced MSSS (PNationMS=0.021; PBIONAT=0.007) and reduced ris…
Is neural network better than logistic regression in death prediction in patients after ST-segment elevation myocardial infarction?
2021
Background: There is a need to develop patient classification methods to adjust post-discharge care, improving survival after ST-segment elevation myocardial infarction (STEMI). Aims: The study aimed to determine whether a neural network (NN) is better than logistic regression (LR) in mortality prediction in STEMI patients. Material and methods: The study included patients from the Polish Registry of Acute Coronary Syndromes (PL-ACS). Patients with the first anterior STEMI treated with the primary percutaneous coronary intervention (pPCI) of the left anterior descending (LAD) artery between 2009 and 2015 and discharged alive were included in the study. Patients were randomly divided into th…
Interdisciplinary Screening, Diagnosis, Therapy and Follow-up of Breast Cancer. Guideline of the DGGG and the DKG (S3-Level, AWMF Registry Number 032…
2018
Geburtshilfe und Frauenheilkunde 78(11), 1056-1088 (2018). doi:10.1055/a-0646-4630