Search results for "temi"

HL7v3 CDA Rel.2 Patient Summary and Chronic Care Model: Localization experience and GP/HS Integration Project

2010

The localization experience for the Patient Summary, based on the Health Level Seven Version 3 (HL7v3) Clinical Document Architecture, Release 2 (CDA Rel.2), is presented. An overview of the Chronic Care Model (CCM) is introduced with particular attention to the clinical information systems, in order to organize patient and population clinical data by sharing information among healthcare providers in management of chronic diseases. We propose, as case study, a project for the integration of various services for General Practitioners (GP) and Hospital Specialists (HS), accessing the Electronic Health Record (EHR), implementing the Patient Summary and managing the exchange of Chronic Care med…

Musical pitch quantization as an eigenvalue problem

2020

How can discrete pitches and chords emerge from the continuum of sound? Using a quantum cognition model of tonal music, we prove that the associated Schrödinger equation in Fourier space is invariant under continuous pitch transpositions. However, this symmetry is broken in the case of transpositions of chords, entailing a discrete cyclic group as transposition symmetry. Our research relates quantum mechanics with music and is consistent with music theory and seminal insights by Hermann von Helmholtz.

Homomorphs and wreath product extensions

1982

A homomorph is a class of (finite soluble) groups closed under the operation Q of taking epimorphic images. (All groups considered in this paper are finite and soluble.) Among those types of homomorphs that have found particular interest in the theory of finite soluble groups are formations and Schunck classes; the reader is referred to (2), § 2, for a definition of those classes. In the present paper we are interested in homomorphs satisfying the following additional closure property:(W0) if A is abelian with elementary Sylow subgroups, then each wreath product A G (with respect to an arbitrary permutation representation of G) with G ∊ is contained in .

“AD HOC” MODIFIED CLAYS FOR BIOTECHNOLOGICAL APPLICATIONS

Nowadays, the scientific community has to face with cogent problems strictly linked to the improvement of quality of live. Among the different tasks to achieve the prefixed objective the focus has been put on the drug administration, i.e., attention has been paid to propose an appropriate solution to improve the performance of a drug delivery system and to eliminate both the side effect and drawbacks. With the aim to achieve the design, synthesis, and characterization of versatile systems, with peculiar characteristics, based on clays and clays modified with a biocompatible surfactant, able to adsorb and release organic substances of pharmaceutical interest the present PhD thesis has been u…

Climate Change and Energy Issues in the North

2011

Highly industrialized societies are mostly responsible for the emerging anthropogenic climate change. There are different ways to measure this responsibility (e.g., whether based on causal contribution or strict responsibility, see Muller et al. 2007). However, regardless of the specific method applied to measure the impact, presently, the USA and the EU are the global leaders in green house gas emissions with countries such as China, India and Brazil following closely behind. Globally, GHG emissions are still increasing among the highly industrialized countries, particularly in the USA – a country that never ratified the Kyoto Protocol. However, the EU has managed to curb its emissions, co…

Joining by forming technologies: current solutions and future trends

2022

AbstractThe progressively more demanding needs of emissions and costs reduction in the transportation industry are pushing engineers towards the use of increasingly lightweight structures. This goal can be achieved only if dissimilar and/or new materials, including polymers and composites, are joined together to create complex structures. Conventional fusion welding processes have often been proven inadequate to this task because of the high heat input reducing the joint mechanical properties or even making the joining process impossible. Joining by forming technologies take advantage on the plastic deformation to create sound joints out of even very dissimilar materials. Over the last 25 y…

Friction Stir Spot Welding of AA6082-T6: influence of the most relevant process parameters and comparison with classic mechanical fastening techniques

2007

The results of an experimental study on friction stir spot welding (FSSW) of AA6082-T6 are reported. In particular, process mechanics is highlighted and joint strength is considered in relation to varying the most relevant process parameters. Furthermore, the results obtained are compared with those derived from the application of traditional mechanical fastening techniques such as clinching and riveting. In this way the effectiveness of FSSW is highlighted.

Novel biosensor-based analytic device for the detection of anti-double-stranded DNA antibodies.

2007

AbstractBackground: Patients with systemic lupus erythematosus (SLE) develop a wide variety of serologic manifestations, including double-stranded DNA autoantibodies (anti-dsDNA). The determination of the potentially pathogenic autoantibodies is diagnostically relevant.Methods: We developed a novel surface plasmon resonance (SPR) biosensor chip for studies of dsDNA and anti-dsDNA binding. A synthetic oligonucleotide was coupled to biotinylated human transferrin, hybridized with the complementary antistrand, and ligated with a human recombinant dsDNA fragment 233 bp in length. After surface immobilization of this antigenic construct, diluted sera from SLE patients and healthy donors were ana…

Canakinumab in Systemic Juvenile Idiopathic Arthritis: Clinical Inactive Disease Rate and Safety in Italian Patients

2020

Introduction: Systemic juvenile idiopathic arthritis (sJIA) accounts for 10-20% of all patients with JIA. The demonstration of a key role of IL-1 and IL-6 in the pathogenesis of the disease, led to consider sJIA an autoinflammatory disease: this explain the successfully use of IL-1 and IL-6 inhibitors. While the efficacy and safety of anakinra in sJIA is widely documented, there are no reports on large series of patients treated with canakinumab outside of the setting of clinical trials. Objectives: The aim of this study was to evaluate clinical response rate and disease course of canakinumab in Italian cohort of patients with sJIA. Methods: This is a retrospective multicenter study. Demogr…

Activity of Artemisinin-Type Compounds Against Cancer Cells

2012

Clinical Oncology strives for complete remission of patients with cancer, but still crusades against multidrug resistance of various cancers. Scientists and clinicians have been challenged to identify new potent anticancer compounds with new targeting strategies. Traditional Chinese Medicine (TCM) provides a large spectrum of medicinal plants containing many biocompounds that possess anticancer activities. These represent a source of molecules that may have antiproliferative effects on a variety of cancers.