Search results for "tendon"
showing 10 items of 240 documents
Value of the Definition of Severe Familial Hypercholesterolemia for Stratification of Heterozygous Patients
2017
Familial hypercholesterolemia (FH) is characterized by high low-density lipoprotein (LDL) cholesterol with co-dominant transmission and high risk of cardiovascular disease (CVD), although with high variability among subjects. Currently, CVD stratification tools for heterozygous FH (HeFH) are not available. A definition of severe HeFH has been recently proposed by the International Atherosclerosis Society (IAS), but it has not been validated. Our study aims to see clinical characteristics and prevalence of CVD in subjects defined as severe HeFH by IAS criteria. Probable or definite HeFH introduced in the Dyslipidemia Registry of Spanish Arteriosclerosis Society were analyzed by the IAS crite…
Posterior tibial tendon dysfunction: Clinical and magnetic resonance imaging findings having histology as reference standard.
2017
Abstract Objective To investigate the correlation between MRI, clinical tests, histopathologic features of posterior tibial tendon (PTT) dysfunction in patients with acquired adult flatfoot deformity surgically treated with medializing calcaneal osteotomy and flexor digitorum longus tendon transposition. Materials and methods Nineteen patients (11 females; age: 46 ± 15 year, range 18–75) were pre-operatively evaluated using the single heel rise (HR) and the first metatarsal rise (FMR) sign tests. Two reviewers graded the PTT tears on a I–III scale and measured the hindfoot valgus angle on the pre-operative MRI of the ankle. The specimens of the removed portion of PTT were histologically ana…
Effects of muscle – tendon length on joint moment and power during sprint starts
2005
The aim of this study was to examine the effects of muscle-tendon length on joint moment and power during maximal sprint starts. Nine male sprinters performed maximal sprint starts from the blocks that were adjusted either to 40 degrees or 65 degrees to the horizontal. Ground reaction forces were recorded at 833 Hz using a force platform and kinematic data were recorded at 200 Hz with a film camera. Joint moments and powers were analysed using kinematic and kinetic data. Muscle - tendon lengths of the medial gastrocnemius, soleus, vastus medialis, rectus femoris and biceps femoris were calculated from the set position to the end of the first single leg contact. The results indicated that bl…
Muscle kinematics during isometric contraction: Development of phase contrast and spin tag techniques to study healthy and atrophied muscles
2004
Purpose To develop and compare phase-contrast (PC) and spin-tag (ST) MR imaging techniques for accurate quantification of velocity and displacement distribution in the muscle tendon complex of the lower leg during isometric contractions under in vivo conditions, in healthy subjects and subjects with atrophy. Materials and Methods Techniques were developed to acquire PC and ST dynamic images, gated to the force exerted by a subject during isometric contraction. Algorithms were optimized for correction of phase shading errors. Flow velocity quantification was validated in phantoms and ex vivo rabbit muscles. Trajectories of pixels calculated from PC images were compared with those in ST image…
In-Vivo Estimation and Repeatability of Force-Length Relationship and Stiffness of the Human Achilles Tendon using Phase Contrast MRI
2008
Purpose To devise a method using velocity encoded phase contrast MRI and MR-compatible dynamometry, for in vivo estimation of elastic properties of the human Achilles tendon and to assess within-session and day-to-day repeatability of this technique. Materials and Methods Achilles tendon force and calcaneus-movement-adjusted displacement were measured during a submaximal isometric plantarflexion in 4 healthy subjects, four repeated trials each. The measured force-length (F-L) relationship was least-squares fitted to a cubic polynomial. Typical error was calculated for tendon displacement at multiple force levels, stiffness from the “linear region,” and transition point from the displacement…
Contribution of the tendinous tissue to force enhancement during stretch–shortening cycle exercise depends on the prestretch and concentric phase int…
2005
When the prestretch intensity and concentric work are increased in stretch-shortening cycle (SSC) exercises, the utilization of the elastic energy can increase during the concentric phase. In order to further understand this process during SSC exercises, the interaction between fascicle-tendinous tissues (TT) of the vastus lateralis (VL) muscle was examined under different prestretch and rebound intensity drop jumps. Ten male subjects participated in the study. Direct VL fascicle lengths (N = 10) and in vivo patellar tendon force (N = 1) were measured together with the electromyographic (EMG) activity of VL during the trials. With increasing drop height but the same rebound height condition…
Interaction between fascicle and tendinous tissues in short-contact stretch-shortening cycle exercise with varying eccentric intensities
2005
The interaction between fascicle and tendinous tissues (TT) in short-contact drop jumps (DJ) with three different drop heights [low (Low), optimal (OP), and high (High)] was examined with 11 subjects. The ground reaction force (F z) and ankle and knee joint angles were measured together with real-time ultrasonography (fascicle length) and electromyographic activities of the medial gastrocnemius (MG) and vastus lateralis (VL) muscles during the movement. With increasing drop height, the braking force and flight time increased from Low to OP ( P < 0.05). In High, the braking force increased but the flight time decreased compared with OP ( P < 0.05). During contact of Low and OP conditi…
A comparison of the triceps surae and residual muscle moments at the ankle during cycling.
1991
The rigid linked system model and principles of inverse dynamics have been widely used to calculate residual muscle moments during various activities. EMG driven models and optimization algorithms have also been presented in the literature in efforts to estimate skeletal muscle forces and evaluate their possible contribution to the residual muscle moment. Additionally, skeletal muscle-tendon forces have been measured, directly, in both animals and humans. The purpose of this investigation was to calculate the moment produced by the triceps surae muscles and compare it to the residual muscle moment at the ankle during cycling at three power outputs (90, 180 and 270 W). Inferences were made r…
Effect of chronic unloading and rehabilitation on human Achilles tendon properties: a velocity-encoded phase-contrast MRI study
2008
The objective of this study was to measure and monitor changes in Achilles tendon mechanical properties and force production capability of triceps surae muscles after 4 wk of limb suspension and 6 wk of physical rehabilitation. Five healthy volunteers underwent unilateral lower limb suspension followed by weekly physiotherapy. A velocity-encoded, phase-contrast magnetic resonance imaging (VE-PC-MRI) technique was used to estimate the tendon strain as a function of force produced during the submaximal isometric contractions. After limb suspension, triceps surae muscle strength decreased to 53.2 ± 15.6% (mean ± SD) of the presuspension level ( P < 0.05). Young's modulus, estimated from the…
Mutations in FAM111B Cause Hereditary Fibrosing Poikiloderma with Tendon Contracture, Myopathy, and Pulmonary Fibrosis
2013
Congenital poikiloderma is characterized by a combination of mottled pigmentation, telangiectasia, and epidermal atrophy in the first few months of life. We have previously described a South African European-descent family affected by a rare autosomal-dominant form of hereditary fibrosing poikiloderma accompanied by tendon contracture, myopathy, and pulmonary fibrosis. Here, we report the identification of causative mutations in FAM111B by whole-exome sequencing. In total, three FAM111B missense mutations were identified in five kindreds of different ethnic backgrounds. The mutation segregated with the disease in one large pedigree, and mutations were de novo in two other pedigrees. All thr…