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showing 10 items of 6745 documents

Photodynamic therapy with verteporfin for subfoveal choroidal neovascularization secondary to pathologic myopia: long-term study.

2006

Purpose: To assess the safety and effectiveness of photodynamic therapy (PDT) with verteporfin for subfoveal choroidal neovascularization (CNV) secondary to pathologic myopia (PM). Methods: Sixty-two patients (62 eyes) with PM underwent PDT according to the guidelines of the Verteporfin in Photodynamic Therapy Study. Clinical evaluations performed at all study visits included measurement of best-corrected Snellen visual acuity, slit-lamp biomicroscopy, and fundus fluorescein angiography. Patients were followed up at 1 month and 3 months after treatment and thereafter at 3-month intervals. Results: The final visual acuity of the study patients, after a median follow-up of 31 months, improved…

AdultMaleRefractive errormedicine.medical_specialtyFovea CentralisVisual acuityPorphyrinsgenetic structuresmedicine.medical_treatmentVisual AcuityPhotodynamic therapyOphthalmologyPathologic myopiamedicineHumansProspective StudiesFluorescein AngiographyDioptreAgedAged 80 and overPhotosensitizing Agentsbusiness.industryVerteporfinGeneral MedicineMiddle Agedmedicine.diseaseVerteporfineye diseasesChoroidal NeovascularizationOphthalmologyLong term learningChoroidal neovascularizationPhotochemotherapyMyopia DegenerativeFemalesense organsmedicine.symptombusinessmyopia subfoveal choroidal neovascularization photodynamic therapy verteporfin.medicine.drugFollow-Up StudiesRetina (Philadelphia, Pa.)
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Clinical analysis following lumbar interspinous devices implant: where we are and where we go

2014

Objectives:We present our experience with patients treated with interspinous devices who are affected by neurogenic intermittent claudication (NIC) or lumbar disc herniation (LDH) where the interspinous system has been inserted following microdiscectomy.Study design:Retrospective study.Methods:This study included patients (n=100) with NIC secondary to lumbar spinal stenosis (group 1), and patients (n=100) with LDH (group 2) in whom the interspinous device has been implanted following radicular decompression in a period spanning 6 years. The latter have been compared with a homogenous group of patients (n=100) where no interspinous system has been implanted following microdiscectomy (group 3…

AdultMaleReoperationMicrosurgerymedicine.medical_specialtyTime FactorsVisual analogue scaleDecompressionlumbar interspinous devicesAdult Prostheses and Implants Aged Decompression Surgical Disability Evaluation Female Follow-Up Studies Intermittent Claudication Intervertebral Disc Displacement Humans Lumbar Vertebrae Microsurgery Minimally Invasive Surgical Procedures Middle Aged Male Retrospective Studies Pain Measurement Patient Satisfaction Surveys and Questionnaires Reoperation Recurrence Treatment Outcome Spinal StenosisDisability EvaluationSpinal StenosisLumbarRecurrenceSurveys and QuestionnairesmedicineHumansMinimally Invasive Surgical ProceduresAgedPain MeasurementRetrospective StudiesLumbar VertebraeSettore MED/27 - Neurochirurgiabusiness.industryLumbar spinal stenosisProstheses and ImplantsGeneral MedicineIntermittent ClaudicationMiddle AgedDecompression Surgicalmedicine.diseaseIntermittent claudicationOswestry Disability IndexSurgeryTreatment OutcomeNeurologyPatient SatisfactionFemaleNeurology (clinical)Implantmedicine.symptombusinessClaudicationIntervertebral Disc DisplacementFollow-Up StudiesSpinal Cord
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Long-Term Results After Liver Transplantation With “Livers That Nobody Wants” Within Eurotransplant: A Center's Experience

2008

Abstract Background Orthotopic liver transplantation (OLT) represents the only curative treatment for end-stage liver disease, but its application is limited because of organ shortages. The purpose of this study was to review the long-term outcomes after OLT during a 2-year period of 45 rescue offers organs within Eurotransplant. Patients and Methods Forty-five deceased donor liver allografts had been officially offered to and rejected by other transplantation centers 162 times prior to our acceptance. Data analysis addressed recurrence of primary disease, ischemic-type biliary lesions (ITBL), re-evaluation or relisting for OLT, re-OLT, as well as overall patient and graft survivals. Result…

AdultMaleReoperationmedicine.medical_specialtyOrthotopic liver transplantationmedicine.medical_treatmentLiver transplantationLiver diseaseCadavermedicineHumansTransplantation HomologousSurvivorsSurvival rateTransplantationbusiness.industryPatient SelectionGraft SurvivalHepatitis CLong term resultsMiddle Agedmedicine.diseaseTissue DonorsLiver TransplantationSurgerySurvival RateTransplantationTreatment Outcomesurgical procedures operativeFemaleSurgeryGraft survivalbusinessLiver FailureTransplantation Proceedings
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Impact of antenatal glucocorticoid therapy and risk of preterm delivery on intelligence in term-born children

2015

Context: Women at risk of preterm delivery are routinely treated with synthetic glucocorticoids (sGCs). Although this therapy substantially reduces neonatal morbidity, concerns remain whether sGC excess may disrupt neurodevelopmental trajectories underlying cognitive functioning. Objective: The present study is the first to disentangle direct effects of antenatal sGC treatment on possible long-term cognitive disadvantages from those of pregnancy complications and prematurity. Design, Setting, and Participants: This cross-sectional study included a mixed-sex cohort of 222 term-born children (aged 6–11 years) consisting of three groups: children of mothers admitted to hospital for threatening…

AdultMaleRisk0301 basic medicinemedicine.medical_specialtyPediatricsTerm BirthCross-sectional studyEndocrinology Diabetes and MetabolismIntelligenceClinical BiochemistryContext (language use)Prenatal careBetamethasoneBiochemistryDexamethasoneCohort Studies03 medical and health sciencesCognitionObstetric Labor Premature0302 clinical medicineEndocrinologyPregnancyHumansMedicineChildGlucocorticoidsIntelligence TestsPregnancybusiness.industryObstetricsBiochemistry (medical)medicine.diseasePregnancy ComplicationsSexual Dysfunction PhysiologicalCross-Sectional Studies030104 developmental biologyPremature birthPrenatal Exposure Delayed EffectsCohortddc:618.97BetamethasoneFemalebusiness030217 neurology & neurosurgerymedicine.drugCohort study
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Liking for fat is associated with sociodemographic, psychological, lifestyle and health characteristics

2014

Sensory liking influences dietary behaviour, but little is known about specifically associated individual profiles. The aim of the present study was to investigate the associations between liking for fat-and-salt and fat-and-sweet sensations and sociodemographic, economic, psychological, lifestyle and health characteristics in a large sample. Individual characteristics and liking scores were collected by a questionnaire among 37 181 French adults. Liking scores were constructed using a validated preference questionnaire. Multinomial logistic regression models were used to assess the associations between liking levels and individual characteristics. In both sexes, subjects belonging to low-l…

AdultMaleRisklikingAdolescent[ SDV.AEN ] Life Sciences [q-bio]/Food and Nutritionhabitude alimentairesociodemographic factorsMedicine (miscellaneous)enquêteHyperphagiapsychological factorsBody Mass IndexCohort StudiesFood PreferencesYoung AdultSurveys and Questionnaires[ SDV.MHEP ] Life Sciences [q-bio]/Human health and pathologyfatSensationHumansObesitysantéLife StyleAgedMultinomial logistic regressionAged 80 and overInternetNutrition and DieteticssociologieCognitionMiddle AgedDietary FatssociodémographiePreferenceLarge sampleobésitéSocioeconomic FactorsFemaleObese subjectsFrancedietary determinantsPsychology[SDV.AEN]Life Sciences [q-bio]/Food and Nutrition[SDV.MHEP]Life Sciences [q-bio]/Human health and pathologyFollow-Up StudiesClinical psychology
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Cancer patients requiring interruption of long-term warfarin because of surgery or chemotherapy induced thrombocytopenia: The use of fixed sub-therap…

2012

No data are available regarding the management of cancer patients requiring interruption of long-term vitamin-K antagonist (VKA) therapy. For this purpose, we tested the efficacy and safety of fixed doses of low-molecular weight heparin (LMWH) in substitution of VKA because of invasive procedures or chemotherapy-induced thrombocytopenia. In cancer patients on VKA, therapy was discontinued 5 ± 1 days before surgery or chemotherapy. Heparin was given at prophylactic dosage in patients at low risk and at fixed subtherapeutic doses (3,800 or 4,000 UI anti-FXa, b.i.d.) in those at high-risk for thrombosis. LMWH was reinitiated 12 hr after surgery and VKA the day after. In patients receiving chem…

AdultMaleRiskmedicine.medical_specialtymedicine.drug_classmedicine.medical_treatmentLow molecular weight heparinAntineoplastic AgentsHemorrhagelow-molecular weight heparin (LMWH); long-term vitamin-K antagonist (VKA) therapy; cancer patientsSettore MED/15 - Malattie Del SanguePostoperative ComplicationsNeoplasmsThromboembolismAtrial FibrillationHumansThrombophiliaMedicinecancer thrombocytopenia low molecular weight heparinProspective StudiesProspective cohort studyAgedAged 80 and overChemotherapybusiness.industryIncidenceWarfarinAnticoagulantsCancerHematologyHeparinHeparin Low-Molecular-WeightMiddle Agedmedicine.diseaseThrombocytopeniaThrombosisSurgeryClinical trialHeart Valve ProsthesisAnesthesialow-molecular weight heparin (LMWH)FemaleWarfarinlong-term vitamin-K antagonist (VKA) therapycancer patientsbusinessmedicine.drugAmerican Journal of Hematology
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Daily eudaimonic well-being as a predictor of daily performance: A dynamic lens.

2019

Sustaining employees' well-being and high performance at work is a challenge for organizations in today's highly competitive environment. This study examines the dynamic reciprocal relationship between the variability in office workers' eudaimonic well-being (i.e., activity worthwhileness) and their extra-role performance. Eighty-three white-collar employees filled in a diary questionnaire twice a day, once in the morning and once in the afternoon, on four consecutive working days. The results show that eudaimonic well-being displays clear variability in a short time frame. In addition, Bayesian Multilevel Structural Equation Models (MSEMs) reveal a significant positive relationship between…

AdultMaleSATISFACTIONmedia_common.quotation_subjectScienceHappiness050109 social psychologyEfficiencyGOALSORGANIZATIONAL CITIZENSHIPJob SatisfactionStructural equation modelingDevelopmental psychologySurveys and Questionnaires0502 economics and businessHumans0501 psychology and cognitive sciencesWorkplaceWORK-ENGAGEMENTWork PerformanceSelf-determination theoryMorningmedia_commonOrganizational citizenship behaviorMultidisciplinaryScience & TechnologyWork engagement05 social sciencesQSELF-DETERMINATION THEORYRBayes TheoremMOTIVATIONMiddle AgedDAILY DIARYMultidisciplinary SciencesJOB CHARACTERISTICSINTRAINDIVIDUAL VARIABILITY8. Economic growthWell-beingHappinessScience & Technology - Other TopicsMedicineFemaleJob satisfactionEMPLOYEESPsychology050203 business & managementPLoS ONE
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Individual differences in working memory capacity are unrelated to the magnitudes of retrocue benefits

2021

AbstractPrevious studies have associated visual working memory (VWM) capacity with the use of internal attention. Retrocues, which direct internal attention to a particular object or feature dimension, can improve VWM performance (i.e., retrocue benefit, RCB). However, so far, no study has investigated the relationship between VWM capacity and the magnitudes of RCBs obtained from object-based and dimension-based retrocues. The present study explored individual differences in the magnitudes of object- and dimension-based RCBs and their relationships with VWM capacity. Participants completed a VWM capacity measurement, an object-based cue task, and a dimension-based cue task. We confirmed tha…

AdultMaleSELECTIONAdolescentINFORMATIONScienceRETRIEVALIndividualityBANDWIDTHnäkömuistiArticle050105 experimental psychologyTask (project management)Correlation03 medical and health sciencesCognition0302 clinical medicineDimension (vector space)PsychologyHumans0501 psychology and cognitive sciencesCONSOLIDATIONMultidisciplinarySHORT-TERM-MEMORYWorking memoryQ05 social sciencesR3112 NeurosciencesAttentional controlObject (computer science)työmuistiREPRESENTATIONShavaintopsykologiaMemory Short-TermMAINTENANCEFeature DimensionSignificant positive correlationMedicineFemaleORIENTING ATTENTIONLOCATIONSkognitiivinen neurotiedePsychology030217 neurology & neurosurgeryNeuroscienceCognitive psychology
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Chronic sacral neuromodulation for treatment of neurogenic bladder dysfunction: long-term results with unilateral implants

2001

Abstract Objectives. To investigate the therapeutic value of sacral neuromodulation in patients with neurogenic disorders in whom conservative treatment options were unsuccessful. Neurogenic disorders may result in various forms of lower urinary tract dysfunction. Methods. Twenty-seven patients (19 women, 8 men) aged 18 to 63 years (mean 44.9 years) were subjected to percutaneous test stimulation of the sacral spinal nerves. Their urologic symptoms consisted of bladder storage failure (n = 15) due to detrusor hyperreflexia and/or bladder hypersensitivity, failure to empty due to detrusor areflexia (n = 11), and combined bladder hypersensitivity and detrusor areflexia (n = 1). Twelve patient…

AdultMaleSacrummedicine.medical_specialtyPercutaneousAdolescentUrologyUrinary systemElectric Stimulation TherapyStimulationNeurological disordermedicineHumansUrinary Bladder NeurogenicNeurogenic bladder dysfunctionbusiness.industryLong term resultsMiddle AgedUrination Disordersmusculoskeletal systemmedicine.diseaseElectrodes ImplantedSurgerySacral nerve stimulationAnesthesiaFemaleImplantbusinessUrology
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Intermediate nerve schwannoma: A rare tumour

2011

The intermediate nerve (IN), also called the nerve of Wrisberg, is a relatively small nerve with a variable anatomical course. Currently, this nerve is not addressed well in the pertinent literature. Pre-operative diagnosis of IN tumours is clinically challenging due to the lack of related symptoms. Symptoms are typically caused by the functional deterioration of neighbouring anatomical structures. In this report, we describe a patient with a schwannoma that arose at the porus acusticus of the internal auditory canal; during surgery, this proved to originate from the IN. We discuss our findings in the context of previously reported cases of IN schwannomas and analyse the vague characteristi…

AdultMaleSchwannomaMagnetic Resonance ImagingNerve of WrisbergDiagnosis DifferentialFacial NerveVestibular schwannomaIntermediate nerveVertigoHumansCranial Nerve NeoplasmsBenign Paroxysmal Positional VertigoFacial Nerve DiseasesNeurilemmoma
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