Search results for "testing"

showing 10 items of 1769 documents

Volatile organic compounds (VOCs) in exhaled breath as a marker of hypoxia in multiple chemical sensitivity

2021

Abstract In the history of diagnostics, breath analysis was one of the first method used until the breakthrough of biochemical testing technology. Today, breath analysis has made a comeback with the development of gas analyzers and e‐noses, demonstrating its power in its applicability for diagnosing a wide range of diseases. The physical basis of multiple chemical sensitivity (MCS), an emerging environmental disease, is difficult to understand because it is based on the scenario of chronic hypoxia, with a complex of chemical compounds that trigger the syndrome and result in multiple symptoms. The aim of this study was to investigate MCS by analyzing exhaled volatile organic compounds (VOCs)…

AdultMalePhysiologyhyperventilationmultiple chemical sensitivityORT test-VOCsBreath testingPhysiology (medical)medicineBiochemical testingHumansQP1-981Breath testVolatile Organic CompoundslactateChromatographymedicine.diagnostic_testChemistryhypoxiaVOCsHypoxia (medical)Middle Agedmedicine.diseaseChronic hypoxiaIncreased lactateORT test‐VOCsBreath gas analysisBreath TestsExhalationFemalemedicine.symptomMultiple chemical sensitivityBiomarkersPhysiological Reports
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Assessing Anxiety with Extrinsic Simon Tasks

2006

This article introduces two new indirect measures of anxiety that are based on the Extrinsic Affective Simon Task (EAST; De Houwer, 2003 ). The EAST differs from the more established Implicit Association Test (IAT; Greenwald, McGhee, & Schwartz, 1998 ) in that participants' responses to different trials within one block of trials are compared rather than performance between two different blocks of trials. Two studies led to the following results: (a) Both extrinsic Simon tasks for assessing anxiety showed only moderate internal consistencies, (b) one of the two tasks showed at least some convergent validity with an IAT for assessing anxiety, and (c) both tasks were dissociated from sel…

AdultMalePsychological TestsDirect assessmentmedia_common.quotation_subjectImplicit-association testExperimental and Cognitive PsychologyGeneral MedicineAnxietyTask (project management)AssociationArts and Humanities (miscellaneous)Convergent validitymedicineHumansPersonalityAnxietyFemalePsychological testingmedicine.symptomPsychologyAssociation (psychology)General Psychologymedia_commonCognitive psychologyExperimental Psychology
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Spontaneous interleukin 2 release of bronchoalveolar lavage cells in sarcoidosis is a codeterminator of prognosis

1996

There is mounting evidence that activated interleukin 2 (IL-2)-releasing lymphocytes play a central role in the immunopathogenesis of sarcoidosis by directing inflammatory reactions and granuloma formation. In the context that a significant proportion of these cells accumulates in the lung and releases mediators, we hypothesized that different immunologically defined stages of sarcoidosis can be identified. A cohort of 89 sarcoidosis patients was allocated to four groups according to the following criteria: stage A, a low number of bronchoalveolar lavage (BAL) lymphocytes (20%) without IL-2 release (1 unit/ml in BAL cell culture supernatant); stage B, BAL lymphocytes20%, with IL-2 release (…

AdultMalePulmonary and Respiratory MedicineInterleukin 2T-LymphocytesContext (language use)InflammationStatistics NonparametricPulmonary function testingSarcoidosis PulmonarymedicineHumansCells CulturedChi-Square DistributionLungmedicine.diagnostic_testbusiness.industryrespiratory systemPrognosismedicine.diseaserespiratory tract diseasesBronchoalveolar lavagemedicine.anatomical_structureImmunologyInterleukin-2FemaleSarcoidosismedicine.symptombusinessBronchoalveolar Lavage FluidProgressive diseaseFollow-Up Studiesmedicine.drugLung
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Impact of SARS-CoV-2 infection in patients with cystic fibrosis in Spain: Incidence and results of the national CF-COVID19-Spain survey

2020

CF-COVID19-Spain Registry Group.

AdultMalePulmonary and Respiratory MedicinePediatricsmedicine.medical_specialtyPneumonia ViralPopulationDiseaseRisk AssessmentCystic fibrosisArticleCystic fibrosisBetacoronavirus03 medical and health sciencesCOVID-19 Testing0302 clinical medicinemedicineHumansRegistries030212 general & internal medicineMortalityeducationPandemicsRetrospective Studieseducation.field_of_studyClinical Laboratory Techniquesbusiness.industrySARS-CoV-2IncidenceIncidence (epidemiology)Mortality rateCOVID-19Retrospective cohort studymedicine.diseaseCoronavirus030228 respiratory systemSpainFemaleObservational studyCoronavirus InfectionsRisk assessmentbusiness
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Depression is associated with poor control of symptoms in asthma and rhinitis: A population-based study

2019

Abstract Background Although many studies have highlighted the link between asthma/rhinitis and depression, it is still unclear which characteristics of these diseases are associated with the risk of depression. We aimed to explore the relationship between depression and asthma or rhinitis in a representative sample of the Italian general population. Methods The data were collected in GEIRD, an Italian multicenter, population-based, multicase-control study. 2227 participants (age 21–86 years, female 50%) underwent standardized interviews, skin prick and lung function tests, and were divided into cases of current asthma (n = 528), rhinitis without asthma (n = 972), and controls (n = 727). Tw…

AdultMalePulmonary and Respiratory Medicinemedicine.medical_specialtyActivities of daily livingPopulationSettore MED/10 - Malattie Dell'Apparato RespiratorioPulmonary function testingAtopyYoung Adult03 medical and health sciences0302 clinical medicineAsthma controlInternal medicinemedicineHumans030212 general & internal medicineMedical prescriptioneducationAgedRhinitisAsthmaAged 80 and overeducation.field_of_studyAtopyDepressionbusiness.industryAnhedoniaGeneral populationMiddle Agedmedicine.diseaseAsthmaPatient Health QuestionnaireItaly030228 respiratory systemAsthma control; Atopy; Depression; General population; Rhinitis controlRhinitis controlFemalemedicine.symptombusinessRespiratory Medicine
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Gender Differences in Health‐Related Quality of Life Among Patients with Asthma

2004

This study has a twofold objective: 1) to explore to what extent suffering from asthma affects the HRQL of men and women differently at several stages of disease severity and 2) to analyze whether the informed poorer HRQL of asthmatic women is related to their higher scores on instruments measuring emotionally disordered symptoms. One hundred fifty-one outpatient asthmatics (84 women and 67 men) completed the Spanish versions of the Asthma Quality of Life questionnaire (AQL), as well as anxiety and depression inventories. A full history, physical examination, and pulmonary function test were performed on all subjects. Patients were classified into one of four asthma severity categories foll…

AdultMalePulmonary and Respiratory Medicinemedicine.medical_specialtyAdolescentPhysical examinationmacromolecular substancesSeverity of Illness IndexPulmonary function testingSex FactorsQuality of lifeSeverity of illnessmedicineHumansImmunology and AllergyDepression (differential diagnoses)AsthmaDepressive Disordermedicine.diagnostic_testbusiness.industryRespiratory diseaseMiddle Agedmedicine.diseaseAnxiety DisordersAsthmarespiratory tract diseasesDyspneaPediatrics Perinatology and Child HealthQuality of LifePhysical therapyAnxietyFemalemedicine.symptombusinessClinical psychologyJournal of Asthma
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3D-printing-assisted fabrication of chitosan scaffolds from different sources and cross-linkers for dental tissue engineering

2021

The aim of the present study was to fabricate and characterise chitosan scaffolds from animal and fungal sources, with or without gelatine as a co-polymer, and cross-linked to 3-glycidyloxyproply trimethoxysilane (GPTMS) or genipin for application in dental root tissue engineering. Chitosan-based scaffolds were prepared by the emulsion freeze-drying technique. Scanning electron microscopy (SEM) and nano-focus computed tomography (nano-CT) were used to characterise scaffold microstructure. Chemical composition and cross-linking were evaluated by Fourier transform infrared-attenuated total reflectance spectroscopy. Compression tests were performed to evaluate scaffold mechanical properties. S…

AdultMaleScaffoldMaterials scienceRD1-811AdolescentCompressive StrengthScanning electron microscopeSimulated body fluid0206 medical engineeringBiocompatible MaterialsDiseases of the musculoskeletal system02 engineering and technologyApatiteChitosanYoung Adultchemistry.chemical_compoundTissue engineeringfungal chitosanDental pulp stem cellsMaterials TestingHumansIridoidsCells CulturedDental PulpChitosanTissue EngineeringTissue ScaffoldsStem Cellstechnology industry and agricultureSilanes020601 biomedical engineeringdental pulp stem cellsRC925-935chemistryvisual_artPrinting Three-Dimensionalvisual_art.visual_art_mediumGenipinSurgeryFemalePorosityBiomedical engineeringEuropean Cells and Materials
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Beta-adrenergic stimulation enhances left ventricular diastolic performance in normal subjects.

1997

To determine the effects of beta-adrenergic stimulation on transmitral Doppler echocardiography flow characteristics of left ventricular diastolic filling, we studied 10 healthy volunteers aged 23-31 years (mean age, 26.6 years) during intravenous infusion of isoprenaline in consecutive steps of 0.1, 0.2, 0.4, 0.75, and 1.5 micrograms/min (each for 15 min). Saline control infusion was given in the same manner in a crossover and blinded protocol. Compared with the infusion of placebo, stepwise increasing doses of isoprenaline caused a dose-related increase in early and late diastolic filling velocities and velocity-time integrals, a lengthening of the acceleration time, and a shortening of t…

AdultMaleStress testingDiastoleHemodynamicsBlood PressureDoppler echocardiographyVentricular Function LeftDouble-Blind MethodHeart RateIsoprenalineHeart ratemedicineHumansInfusions IntravenousPharmacologyAnalysis of VarianceCross-Over Studiesmedicine.diagnostic_testDose-Response Relationship Drugbusiness.industryIsoproterenolAdrenergic beta-AgonistsEchocardiography DopplerBlood pressureAnesthesiaCirculatory systemCardiology and Cardiovascular Medicinebusinessmedicine.drugJournal of cardiovascular pharmacology
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Modeling the impact of soft tissue on axial transmission measurements of ultrasonic guided waves in human radius

2008

Recent in vitro and simulation studies have shown that guided waves measured at low ultrasound frequencies (f=200 kHz) can characterize both material properties and geometry of the cortical bone wall. In particular, a method for an accurate cortical thickness estimation from ultrasound velocity data has been presented. The clinical application remains, however, a challenge as the impact of a layer of soft tissue on top of the bone is not yet well established, and this layer is expected to affect the dispersion and relative intensities of guided modes. The present study is focused on the theoretical modeling of the impact of an overlying soft tissue. A semianalytical method and finite-differ…

AdultMaleTime FactorsMaterials scienceAcoustics and UltrasonicsAcousticsModels BiologicalMotionYoung AdultOpticsArts and Humanities (miscellaneous)Image Interpretation Computer-AssistedmedicineHumansComputer SimulationTime domainDispersion (water waves)AgedUltrasonographyAged 80 and overGuided wave testingbusiness.industryUltrasoundBiomechanicsReproducibility of ResultsNumerical Analysis Computer-AssistedRadiusMiddle AgedRadiusmedicine.anatomical_structureConnective TissueFemaleUltrasonic sensorCortical bonebusinessThe Journal of the Acoustical Society of America
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Three-year clinical performance of two indirect composite inlays compared to direct composite restorations

2013

Objective: Despite the incremental build-up of resin composite restorations, their polymerization shrinkage during curing presents a serious problem. Indirect composite resin systems represent an alternative in overcoming some of the deficiencies of direct composite restorations. The hypothesis of the present study states that the clinical performance of restorations may be affected by different generation and application techniques. Study Design: Sixty restorations (20 DI system (Coltene/Whaledent AG, Altstatten, Switzerland) composite inlays, 20 Tescera ATL system (BISCO Inc. Schaumburg, Illinois, USA) composite inlays, and 20 direct composites) were applied to premolar teeth in 49 patien…

AdultMaleTime FactorsResin compositeResin restorationsComposite numberDentistryOdontologíaComposite ResinsDental Restoration WearClinical studyBiomaterials and Bioengineering in DentistryMaterials TestingPremolarmedicineHumansGeneral DentistryInlaybusiness.industrytechnology industry and agricultureClinical performance:CIENCIAS MÉDICAS [UNESCO]Ciencias de la saludDental Restoration Wearmedicine.anatomical_structureOtorhinolaryngologyInlaysUNESCO::CIENCIAS MÉDICASResearch-ArticleFemaleSurgerybusinessMedicina Oral Patología Oral y Cirugia Bucal
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