Search results for "testing"

showing 10 items of 1769 documents

Cutaneous Lupus Erythematosus

2008

Lupus erythematosus (LE) is an inflammatory autoimmune disease, characterized by a heterogeneous clinical presentation. The skin lesions are one of the most frequent symptoms of the disease and present with a broad spectrum of LE-nonspecific and LE-specific cutaneous manifestations. Therefore, the development of a classification for skin lesions in the disease has proven difficult. For example, the LE-nonspecific cutaneous manifestations include livedo racemosa, thrombophlebitis, and leukocytoclastic vasculitis and can be associated with high disease activity and systemic organ involvement. The LE-specific cutaneous manifestations encompass the subtypes of cutaneous lupus erythematosus (CLE…

Autoimmune diseasemedicine.medical_specialtyLupus erythematosusmedicine.diagnostic_testbusiness.industryfungiDiseaseLivedo racemosamedicine.diseaseThrombophlebitisDermatologySkin biopsyPhototestingmedicineCutaneous Lupus ErythematosusAntimalarial Agentmedicine.symptombusinessPanniculitisSkin lesionTherapeutic strategyAnti-SSA/Ro autoantibodies
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Factorial structure of recklessness: To what extent are older drivers different?

2003

This study tests whether the original factorial structure of a recklessness questionnaire can be maintained for the current Spanish population of older drivers.Our recent interest in dedicating special attention to senior citizen mobility (Monterde, 2001), is due to the impending increase of the aging population in Western countries; this has led us to reinitiate the psychometric study of the construct validity, revising and including older drivers in the psychometric aspects of those evaluation instruments that will then be used in the Spanish psycho-medical check of drivers and in research.Factorial analysis was used to determine validity.There was an appearance of a different psychologic…

Automobile DrivingEngineeringPopulation ageingPsychometricsApplied psychologyPoison controlAffect (psychology)Computer securitycomputer.software_genreTraffic psychologySurveys and QuestionnairesInjury preventionHumansPsychological testingSafety Risk Reliability and QualityAgedbusiness.industryAccidents TrafficAge FactorsConstruct validityAttitudeGeriatricsSafetyRecklessnessbusinessRisk Reduction BehaviorcomputerJournal of Safety Research
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Protocol for developing a mental imagery intervention: a randomised controlled trial testing a novel implementation imagery e-health intervention to …

2019

IntroductionDrowning due to driving into floodwater accounts for a significant proportion of all deaths by drowning. Despite awareness campaigns such as 'If it's flooded, forget it', people continue to drive into floodwater. This causes loss of life, risk to rescuers and damage to vehicles. The aim of this study was to develop and evaluate an online e-health intervention to promote safe driving behaviour during flood events.Methods and analysisThe study will use a 2×3 randomised controlled trial in which participants are randomised into one of two conditions: (1) education about the risks of driving into floodwater or (2) education about the risks of driving into floodwater plus a theory-ba…

Automobile Drivingsocial-cognitive theoriesflooded waterwaysClinical Sciencesdriver behaviourIntentionriskikäyttäytyminenRisk-TakingmielikuvaharjoitteludrivingHumansImageryliikenneturvallisuusteleterveydenhuoltoturvallisuuskasvatusRandomized Controlled Trials as Topicmental imagerywater safetyOther Medical and Health Sciencesdrowningrandomised controlled trial testingliikennekäyttäytyminentulvatTelemedicineFloodsPsychotherapyPublic Health and Health Servicesmental imagery interventione-health intervention
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Axia ierīču VMode funkcijas un palīgizeju testu automatizācija

2017

Kvalifikācijas darbs apraksta Axia Power Station un Axia Fusion testēšanas sistēmas VMode un Aux Sends izstrādi. Sistēma pārbauda VMode funkcionalitāti Axia Power Station (APS) un Axia Fusion gan Standarta Livewire audio straumei, gan Surround audio straumei. Tas arī pārbauda četrus Aux Sends (Aux Send A, Aux Send B, Aux Send C un Aux Send D) Axia Fusion dažādos ‘Gain’ kontrollos. Sistēma ir paredzēta lietotājiem, kuri strādā ar Axia Power Stations un Axia Fusions.

Aux SendsDatorzinātneTestingTest automationAxiaVMode
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Safety, tolerability, pharmacokinetics, pharmacodynamics, and exploratory efficacy of the novel enzyme replacement therapy avalglucosidase alfa (neoG…

2019

This multicenter/multinational, open-label, ascending-dose study (NCT01898364) evaluated safety, tolerability, pharmacokinetics, pharmacodynamics, and exploratory efficacy of repeat-dose avalglucosidase alfa (neoGAA), a second-generation, recombinant acid α-glucosidase replacement therapy, in late-onset Pompe disease (LOPD). Patients ≥18 years, alglucosidase alfa naïve (Naïve) or previously receiving alglucosidase alfa for ≥9 months (Switch), with baseline FVC ≥50% predicted and independently ambulatory, received every-other-week avalglucosidase alfa 5, 10, or 20 mg/kg over 24 weeks. 9/10 Naïve and 12/14 Switch patients completed the study. Avalglucosidase alfa was well-tolerated; no deaths…

Avalglucosidase alfa (neoGAA)0301 basic medicineMaleGLUCOSE TETRASACCHARIDELysosomal acid alpha-glucosidase (GAA) deficiencyCHILDRENPulmonary function testingMOTOR FUNCTION0302 clinical medicineMedicineGenetics (clinical)Late-onset Pompe disease (LOPD)Glycogen Storage Disease Type IIAlglucosidase alfaMOUSE MODELEnzyme replacement therapyMiddle AgedTreatment OutcomeNeurologyTolerabilityEnzyme replacement therapySKELETAL-MUSCLEFemaleLife Sciences & BiomedicineMUSCLE TRAINING RMTGlycogen6-MINUTE WALKmedicine.drugAdultmedicine.medical_specialtyClinical NeurologyGLYCOGEN03 medical and health sciencesFEV1/FVC ratioPharmacokineticsInternal medicineHumansEnzyme Replacement TherapyAdverse effectAlglucosidase alfaScience & Technologybusiness.industryNeurosciencesalpha-GlucosidasesADULTSGlycogen storage disease type IISEVERITY030104 developmental biologyPharmacodynamicsPediatrics Perinatology and Child HealthNeurosciences & NeurologyNeurology (clinical)Glucan 14-alpha-Glucosidasebusiness030217 neurology & neurosurgeryNeuromuscular Disorders
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Folate-targeted supramolecular vesicular aggregates based on polyaspartyl-hydrazide copolymers for the selective delivery of antitumoral drugs.

2010

Supramolecular vesicular aggregates (SVAs) have the advantage of combining the safe and biocompatible properties of colloidal vesicular carriers based on phospholipids with those of polymeric materials, i.e. polyaspartyl-hydrazide (PAHy) copolymers. To provide SVAs with a certain tumour selectivity, folate moieties were chemically conjugated to PAHy copolymers. Physicochemical properties (mean sizes, polydispersity index and zeta potential) of folate-targeted SVAs (FT-SVAs) loaded with gemcitabine were evaluated. The antiproliferative and anticancer activity of gemcitabine-loaded FT-SVAs was evaluated against two cancer cell lines, i.e. MCF-7 cells which over-express the folate receptor and…

AzidesMaterials sciencePolymersBiophysicsBioengineeringAntineoplastic AgentsBiocompatible MaterialsPharmacologyDeoxycytidineFlow cytometryBiomaterialsDrug Delivery SystemsFolic AcidIn vivoCell Line TumorMaterials TestingmedicineHumansTissue DistributionCytotoxicityLiposomeDrug CarriersMicroscopy Confocalmedicine.diagnostic_testMolecular StructureGemcitabineIn vitroDRUG DELIVERY POLYASPARTYLHYDRAZIDE FOLATESettore CHIM/09 - Farmaceutico Tecnologico ApplicativoMechanics of MaterialsCell cultureFolate receptorDrug deliveryCeramics and CompositesBiophysicsPeptidesBiomaterials
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2,2-Di­fluoro-3-(4-fluoro­phen­yl)-2H-benzo[e][1,3,2]oxaza­borinin-3-ium-2-uide

2017

There is one independent molecule in the asymmetric unit of the title compound, C13H9BF3NO, which crystallizes in the non-centrosymmetric space groupCc. In the molecular structure, the BF2-carrying ring is distorted from planarity and its mean plane makes a dihedral angle of 42.3 (1)° with the 4-fluorophenyl ring. F atoms are involved in all of the short intermolecular contacts of the crystal structure, which link molecules to form chains along [001] and [010].

BF2−salicylatescrystal structureChemistryCrystal structureDihedral angle010402 general chemistry010403 inorganic & nuclear chemistryRing (chemistry)01 natural sciencesPlanarity testing0104 chemical sciencesBF2 complexesCrystallographylcsh:QD901-999Moleculelcsh:CrystallographyUnit (ring theory)IUCrData / International Union of Crystallography
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Tecniche di Test Innovative per la Caratterizzazione di Memorie a Gate Flottante

L’affidabilità nella ritenzione dei dati memorizzati è una delle problematiche fondamentali delle memorie flash; esse vengono normalmente testate, in produzione con procedure specifiche implementate su ATE (Automated Test Equipments), per rilevare problemi di lettura, programmazione e cancellazione; vengono inoltre provate altre procedure per identificare possibili faults e per il corretto trimming dei parametri interni. Oggi, il testing classico con ATE è supportato dalle tecniche BIST (Built-In-Self-Test), tramite le quali si prevede in progetto, all’interno dei circuiti integrati, una parte di hardware e software supplementari per permettere l’auto-test (funzionale e/o parametrico), così…

BISTSBSTMemorie FlashPortable ATECaratterizzazione MemorieTestingFloating GateTesting MemorieATESettore ING-INF/01 - ElettronicaMemorie Flash; Floating Gate; Testing; BIST; SBST; Portable ATE; ATE; Caratterizzazione Memorie; Testing Memorie;
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Mortality and demographic recovery in early post-black death epidemics: Role of recent emigrants in medieval Dijon

2020

International audience; Objective and methodsWe analyze the influence of population movement on susceptibility to death and resilience during two epidemics occurring in Dijon soon after the Black Death. Using a specific program designed to propose links between entries in annual tax registers, we define tentative heads of household, the elapsed time since their first registration and their ties with other persons within the city.ResultsDuring the 1400 epidemic heads of household who were registered for 1–3 years die in large numbers, whereas during years without epidemics, their death rate is lower than that of heads of household who were registered longer. Recent registration is an epidemi…

Bacterial DiseasesMaleTime FactorsEpidemiologyChi Square TestsVulnerability factorDisease OutbreaksGeographical LocationsMathematical and Statistical Techniques0302 clinical medicineMedicine and Health SciencesPublic and Occupational HealthHistory 15th Centurymedia_common[SDV.EE]Life Sciences [q-bio]/Ecology environmentFamily Characteristics0303 health scienceseducation.field_of_studyMultidisciplinaryIncidenceIncidence (epidemiology)Mortality rateStatisticsQRSocioeconomic Aspects of HealthEuropeSurvival RateProfessionsInfectious DiseasesGeographyPhysical SciencesFamineMedicineFemaleFrancePsychological resilienceResearch ArticleDeath Ratesmedia_common.quotation_subjectScience030231 tropical medicinePopulationBlack DeathEmigrants and ImmigrantsResearch and Analysis MethodsInfectious Disease Epidemiology03 medical and health sciencesPopulation MetricsHumansStatistical MethodseducationStatistical Hypothesis TestingSocioeconomic statusDemography030304 developmental biologyPlaguePopulation BiologyBiology and Life SciencesHistory MedievalPlaguesEmigrationHealth CareSocioeconomic FactorsPeople and PlacesPopulation Groupings[SDE.BE]Environmental Sciences/Biodiversity and EcologyMathematicsDemography
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On-board Energy Consumption Assessment for Symbolic Execution Models on Embedded Devices

2020

Internet of Things (IoT) applications operate in several domains while requiring seamless integration among heterogeneous objects. Regardless of the specific platform and context, IoT applications demand high energy efficiency. Adopting resource-constrained embedded devices for IoT applications means ensuring low power consumption, low maintenance costs and possibly longer battery life. Meeting these requirements is particularly arduous as programmers are not able to monitor the energy consumption of their own software during development or when applications are finally deployed. In this paper, we discuss on-board real-time energy evaluation of both hardware and software during the developm…

Battery (electricity)Computer sciencebusiness.industry020206 networking & telecommunicationsContext (language use)02 engineering and technologyEnergy consumptionSymbolic executionEmbedded deviceSoftware testing020202 computer hardware & architectureInternet of Things (IoT)Energy UtilizationOn boardSoftwarePower ManagementEmbedded systemEnergy Assessment0202 electrical engineering electronic engineering information engineeringResource-constrained DeviceBaseline (configuration management)businessEnergy (signal processing)
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