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Adaptive Kernel Learning for Signal Processing
2018
Adaptive filtering is a central topic in digital signal processing (DSP). By applying linear adaptive filtering principles in the kernel feature space, powerful nonlinear adaptive filtering algorithms can be obtained. This chapter introduces the wide topic of adaptive signal processing, and explores the emerging field of kernel adaptive filtering (KAF). In many signal processing applications, the problem of signal estimation is addressed. Probabilistic models have proven to be very useful in this context. The chapter discusses two families of kernel adaptive filters, namely kernel least mean squares (KLMS) and kernel recursive least‐squares (KRLS) algorithms. In order to design a practical …
Scatter Search and Path Relinking: Foundations and Advanced Designs
2004
Scatter Search and its generalized form Path Relinking, are evolutionary methods that have been successfully applied to hard optimization problems. Unlike genetic algorithms, they operate on a small set of solutions and employ diversification strategies of the form proposed in Tabu Search, which give precedence to strategic learning based on adaptive memory, with limited recourse to randomization. The fundamental concepts and principles were first proposed in the 1970s as an extension of formulations, dating back to the 1960s, for combining decision rules and problem constraints. (The constraint combination approaches, known as surrogate constraint methods, now independently provide an impo…
MEN1 Disease Occurring Before 21 Years Old: A 160-Patient Cohort Study From the Groupe d'étude des Tumeurs Endocrines
2015
Multiple endocrine neoplasia Type-1 (MEN1) in young patients is only described by case reports.To improve the knowledge of MEN1 natural history before 21 years old.Obtain a description of the first symptoms occurring before 21 years old (clinical symptoms, biological or imaging abnormalities), surgical outcomes related to MEN1 Neuro Endocrine Tumors (NETs) occurring in a group of 160 patients extracted from the "Groupe d'étude des Tumeurs Endocrines" MEN1 cohort.The first symptoms were related to hyperparathyroidism in 122 cases (75%), pituitary adenoma in 55 cases (34%), nonsecreting pancreatic tumor (NSPT) in 14 cases (9%), insulinoma in 20 cases (12%), gastrinoma in three cases (2%), mal…
An adoption model for mobile banking in Ghana
2009
The impact of social and cultural factors on the adoption of technology still requires much research. To investigate it more fully, we examine the reasons for the adoption and non-adoption of mobile banking in Ghana. Through a survey of 271 people in Ghana, it has been found that social and cultural factors in the form of perceived credibility, facilitating conditions, perceived elitisation and demographic factors do play a significant role in adoption decisions. It has been found that elitisation of technology and services can be a positive influence for adopters whilst being a negative influence for non-adopters. In addition, perceived credibility and facilitating conditions also influenc…
Pore Length Effect on Drug Uptake and Delivery by Mesoporous Silicas
2012
The capability of UVM-7 silicas to work as supports for drug storage and delivery is investigated using ibuprofen as a model. UVM-7 silicas are surfactant-assisted synthesised mesoporous materials displaying a characteristic bimodal pore architecture related to their nanoparticulate texture. Strict control of the drug-charge protocol allows the achievement of high ibuprofen loads, not only because of the availability of intra-nanoparticle mesopores and large textural voids, but also owing to the decrease in pore-blocking effects (with regard to related unimodal mesoporous materials such as MCM-41) achieved through the shortening of the mesopore length. The UVM-7/ibuprofen nanocomposites are…
Some intriguing items in the history of adsorption
1994
Abstract Clay was already used in antiquity as a drying and bleaching agent, a carrier for paints, and for various medical purposes. Sand was applied for water desalination. Charcoal was recommended as an antidote Based on Lowitz' discovery of the decolorizing effect in 1785, charcoal was used for the purification first of sugar. The patents of Ostrejko in 1900 opened the way for its industrial application. Already in the Bible we find the description of an adsorption experiment. The systematic research began 1773 when Scheele observed the adsorption of air by charcoal using a volumetric apparatus. The first adsorption measuring instruments were hygrometers as described by Nicholas of Cues …
Project Method in Adult Education: Self-Experience Analysis
2015
<p><em>The </em><em>project methodhas swiftly gained ground in education and it has nowbecome integral to the education process offering new ways for modernizing the education environment.Implementing projects provides learning opportunities for all of the involved parties – students, teachers, school principals and parents. In this article the Author has analysed the characteristics of the project method and the differences between project-based adult learningand non-adult learning,and the impact ofglobalization on projects. Projects can be implemented not only in the scope of specific subjects or specific schools but also as cooperation projects among schools of di…
Transformative Learning, Bildung and Biographical Research
2017
The objective of this chapter, as the title states, is to relate transformative learning and Bildung within the context of biographical research. If processes of Bildung are defined as changes of attitude towards the world and the self, which is a consensus of Bildungs-oriented biographical research in Germany, and if one agrees furthermore that transformative learning and Bildung go together with fundamental changes of the self or the identity, it is rather surprising to note that both discourses have hardly ever been related.
Endometrial receptivity revisited: endometrial transcriptome adjusted for tissue cellular heterogeneity
2018
Study question Does cellular composition of the endometrial biopsy affect the gene expression profile of endometrial whole-tissue samples? Summary answer The differences in epithelial and stromal cell proportions in endometrial biopsies modify the whole-tissue gene expression profiles and affect the results of differential expression analyses. What is already known Each cell type has its unique gene expression profile. The proportions of epithelial and stromal cells vary in endometrial tissue during the menstrual cycle, along with individual and technical variation due to the method and tools used to obtain the tissue biopsy. Study design, size, duration Using cell-population specific trans…
Standardisation of diet and exercise in clinical trials of NAFLD-NASH: Recommendations from the Liver Forum
2019
Abstract: Lifestyle modification is the foundation of treatment recommendations for non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH). The design of clinical trials in NASH may be impeded by the lack of a systematic approach to identify and evaluate how lifestyle changes and/or modifications influence clinical trial outcomes and associated endpoints. Furthermore, there are additional uncertainties regarding the methods that can be utilised to better characterise and quantify lifestyle variables - which can influence disease activity and alter trial endpoints - to allow for comparisons of trial outcomes across different phases of research and/or within drug-c…