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showing 10 items of 8951 documents
Genetic risk prediction and neurobiological understanding of alcoholism.
2014
We have used a translational Convergent Functional Genomics (CFG) approach to discover genes involved in alcoholism, by gene-level integration of genome-wide association study (GWAS) data from a German alcohol dependence cohort with other genetic and gene expression data, from human and animal model studies, similar to our previous work in bipolar disorder and schizophrenia. A panel of all the nominally significant P-value SNPs in the top candidate genes discovered by CFG (n=135 genes, 713 SNPs) was used to generate a genetic risk prediction score (GRPS), which showed a trend towards significance (P=0.053) in separating alcohol dependent individuals from controls in an independent German…
Childhood Environmental and Genetic Predictors of Adulthood Obesity: The Cardiovascular Risk in Young Finns Study
2011
Obesity from childhood to adulthood is associated with adverse health later in life. Increased youth BMI is a risk factor for later obesity, but it is unknown whether identification of other risk factors, including recently discovered genetic markers, would help to identify children at risk of developing adult obesity.Our objective was to examine the childhood environmental and genetic predictors of adult obesity.We followed 2119 individuals of the Cardiovascular Risk in Young Finns Study for up to 27 yr since baseline (1980, age 3-18 yr).We evaluated adult obesity [body mass index (BMI) ≥ 30 kg/m(2)].The independent predictors (P0.05) of adult obesity included childhood BMI, C-reactive pro…
The taboo against group contact: Hypothesis of Gypsy ontologization
2007
The concept of this article is that the symbolic relationships between human beings and animals serve as a model for the relationships between the majority and the ethnic minority. We postulate that there are two representations that serve to organize these relationships between human beings and animals: a domestic and a wild one. If the domestic animal is an index of human culture, the wild animal is an index of nature which man considers himself to share with the animal. With the wild representation, contact with the animal will be taboo, as it constitutes a threat to the anthropological difference. We offer the hypothesis that ontologization of the minority, that is, the substitution of …
Peer-Led or Expert-Led Intervention in HIV Prevention Efficacy? A Randomized Control Trial Among Spanish Young People to Evaluate Their Role
2017
HIV new infections still affect young people around the world. In this context, behavioral interventions seem to be effective in promoting safe sex although some conditions are still inconclusive in different regions. For example, there is insufficient evidence about who may be the best facilitator. For this reason, this study evaluates the effectiveness of peer and expert facilitators for HIV prevention aimed at Spanish young people. For this purpose 225 Spanish college students, aged between 18 and 25 (74.20% women and 25.80% men), were involved in an experimental design to evaluate the facilitators’ effect in a brief intervention for HIV prevention. Participants’ results were measured b…
Evidence for gesture-speech mismatch detection impairments in schizophrenia.
2019
Patients with schizophrenia suffer from impairments in the perception and production of gestures. The extent to which patients can access the semantic association between speech and co-verbal gestures in concrete or abstract/metaphorical meaning contexts is unknown. We investigated 1) how patients differ from controls in gesture matching performance, 2) how performance differs in the context of abstract versus concrete meaning, and 3) whether formal thought disorder (FTD) symptom severity predicts task impairment. Forty-five patients with schizophrenia spectrum disorders (two subgroups, mild and severe) took part in this study. Participants were presented with video clips, each showing an a…
Why have I failed? Why have I passed? A comparison of students’ causal attributions in second language acquisition (A1–B2 levels)
2019
Background Previous literature highlights the importance of causal attributions in achievement and motivation. However, the studies about causal attributions in second language acquisition (SLA) are limited and scarce. Aims This study was designed to determine the frequency of successful and unsuccessful activities per English level and to compare the causal attributions (explanations of outcomes) on successful and failure authentic tasks undertaken in the context of learning English as a foreign language (EFL) acquisition in an Official School of Languages (OSL). Sample To this aim, 407 native Spanish students from levels A1 (n = 111), A2 (n = 113), B1 (n = 98), and B2 (n = 85) in OSL part…
Brand Discrimination: An Implicit Measure of the Strength of Mental Brand Representations
2015
While mental associations between a brand and its marketing elements are an important part of brand equity, previous research has yet to provide a sound methodology to measure the strength of these links. The following studies present the development and validation of an implicit measure to assess the strength of mental representations of brand elements in the mind of the consumer. The measure described in this paper, which we call the Brand Discrimination task, requires participants to identify whether images of brand elements (e.g. color, logo, packaging) belong to a target brand or not. Signal detection theory (SDT) is used to calculate a Brand Discrimination index which gives a measure …
Association between nutritional values of hays fed to horses and sensory properties as perceived by human sight, touch and smell
2019
International audience; Although hay is the foundation of most equine diets, horse owners rarely ask for biochemical analysis and the routine practice is to choose hay based on its 'perceived' nutritional value. The present study aimed at exploring the relationship between sensory properties as perceived by sight, touch and smell, and the nutritional value of hay measured by biochemical analysis using a 'free sorting task' method. Fifty-four non-expert participants were asked individually to: (1) observe 21 hays samples, (2) group together hays that they perceived as similar for each of the three modalities (hay appearance, odour or texture) and (3) characterize each formed group with a max…
Speech Perception: Phonological Neighborhood Effects on Word Recognition Persist Despite Semantic Sentence Context
2019
This study tested the hypothesis that two lexical properties, both phonological neighborhood density (ND) and neighborhood frequency (NF), influence the recognition of target words when preceded by either a semantically congruent or semantically neutral context. Our study is the first to test this hypothesis using a language other than English (i.e., Spanish). We used highly familiar bisyllabic nouns with medium-frequency occurrence as target words, and we expected recognition accuracy to increase as ND and NF decreased in both semanticallly congruent and semantically neutral sentences. We presented 48 undergraduate listeners with a set of 80 words, differing in ND and NF, within these two…
Proactive interference of a sequence of tones in a two-tone pitch comparison task
2000
Subjects compared pitches of a standard tone and a comparison tone separated by 1,300-3,000 msec and responded according to whether the comparison tone sounded higher or lower in pitch than the standard tone. Three interfering tones at 300-msec intervals were presented before each pair of tones. Their pitch range varied, being either below or above the pitch of the standard tone; in some of the trials, their pitches were identical to the pitch of the standard tone (no interference). The highest error rate in performance was found when the interfering tones and the comparison tone deviated in the same direction in pitch from the standard tone. In turn, their deviations in the opposite direct…