Search results for "throughput"
showing 10 items of 483 documents
Resource sharing optimality in WiFi infrastructure networks
2009
In WiFi networks, mobile nodes compete for accessing a shared channel by means of a random access protocol called Distributed Coordination Function (DCF). Although this protocol is in principle fair, since all the stations have the same probability to transmit on the channel, it has been shown that unfair behaviors may emerge in actual networking scenarios. Assuming that a contending node can dynamically change its strategy, by tuning its contention parameters to non-standard values on the basis of channel observations, we prove that, for infrastructure networks with bidirectional traffic and homogeneous application requirements, selfish access strategies are able to reach equilibrium condi…
Performance analysis of selfish access strategies on WiFi infrastructure networks
2009
In this paper we propose a game-theoretic approach for characterizing WiFi network performance in presence of intelligent nodes employing cognitive functionalities. We assume that a cognitive WiFi node is aware of its application requirements and is able to dynamically estimate the network status, in order to dynamically change its access strategy by tuning the contention window settings. We prove that, for infrastructure networks with bidirectional traffic and homogeneous application requirements, selfish access strategies are able to reach equilibrium conditions, which are also Pareto optimal. Indeed, we show that the station strategies converge toward values which maximize a per-node uti…
The Influence of LOS Components on the Statistical Properties of the Capacity of Amplify-and-Forward Channels
2009
Also available from publisher: http://dx.doi.org/10.4236/wsn.2009.11002 Amplify-and-forward channels in cooperative networks provide a promising improvement in the network coverage and system throughput. Under line-of-sight (LOS) propagation conditions in such cooperative networks, the overall fading channel can be modeled by a double Rice process. In this article, we have stud-ied the statistical properties of the capacity of double Rice fading channels. We have derived the analytical expressions for the probability density function (PDF), cumulative distribution function (CDF), level- crossing rate (LCR), and average duration of fades (ADF) of the channel capacity. The obtained results ar…
UDP flows in Cognitive Radios with Channel Aggregation and Fragmentation: A Test-bed Based Evaluation
2018
Channel aggregation (CA) and channel fragmentation (CF) have been studied extensively in cognitive radios (CRs) for many years. However, a test-bed evaluation for such techniques at flow level is still open. In this study, employing National Instruments devices, a test-bed is set up to evaluate the performance of UDP flows for CRs with CA and CF, considering the aspects of blocking, preemption, and throughput in probability. The measurements clearly show that there are performance improvements in applying CA and CF in CRs for UDP flows.
Reliable Underlay Device-to-Device Communications on Multiple Channels
2019
Device-to-device (D2D) communications provide a substantial increase in spectrum usage and efficiency by allowing nearby users to communicate directly without passing their packets through the base station (BS). In previous works, proper channel assignment and power allocation algorithms for sharing of channels between cellular users and D2D pairs, usually require exact knowledge of the channel-state-information (CSI). However, due to the non-stationary wireless environment and the need to limit the communication and computation overheads, obtaining perfect CSI in the D2D communication scenario is generally not possible. In this work, we propose a joint channel assignment and power allocati…
Efficiency analysis of burst transmissions with block ACK in contention-based 802.11e WLANs
2005
The channel utilization efficiency of the standard 802.11 networks is severely compromised when high data transmission rates are employed, since physical layer headers and control frames are transmitted at low rate, thus wasting more channel time, proportionally. The extensions defined in the emerging 802.11e for quality-of-service (QoS) provisioning include some new mechanisms developed in order to improve the efficiency. Those include data transmission bursting (referred to as TXOP operation) and acknowledgment aggregation (referred to as block ACK). These two features allow it to offer new data transmission services, in which the data delivery and acknowledgment unit is not a single fram…
WLC24-1: Dynamic MAC Parameters Configuration for Performance Optimization in 802.11e Networks
2006
Quality of service support in wireless LAN is a theme of current interest. Several solutions have been proposed in literature in order to protect time-sensitive traffic from best-effort traffic. According to the EDCA proposal, which is a completely distributed solution, the service differentiation is provided by giving probabilistically higher number of channel accesses to stations involved in real-time applications. To this purpose, the MAC parameter settings of each contending stations can be tuned dynamically. In this paper, we face the problem of tuning the EDCA MAC parameters in common scenarios in which a given number of low-rate delay-sensitive traffic flows share the channel with so…
Comparison of virtual high-throughput screening methods for the identification of phosphodiesterase-5 inhibitors.
2011
Reliable and effective virtual high-throughput screening (vHTS) methods are desperately needed to minimize the expenses involved in drug discovery projects. Here, we present an improvement to the negative image-based (NIB) screening: the shape, the electrostatics, and the solvation state of the target protein’s ligand-binding site are included into the vHTS. Additionally, the initial vHTS results are postprocessed with molecular mechanics/generalized Born surface area (MMGBSA) calculations to estimate the favorability of ligand-protein interactions. The results show that docking produces very good early enrichment for phosphodiesterase-5 (PDE-5); however, in general, the NIB and the ligand-…
TWJ-Screen: an isothermal screening assay to assess ligand/DNA junction interactions in vitro
2017
International audience; The quest for chemicals able to operate at selected genomic loci in a spatiotemporally controlled manner is desirable to create manageable DNA damages. Mounting evidence now shows that alternative DNA structures, including G-quadruplexes and branched DNA (or DNA junctions), might hamper proper progression of replication fork, thus triggering DNA damages and genomic instability. Therefore, small molecules that stabilize these DNA structures are currently scrutinized as a promising way to create genomic defects that cannot be dealt with properly by cancer cells. While much emphasis has been recently given to G-quadruplexes and related ligands, we report herein on three…
Metabolic and Functional Genomic Studies Identify Deoxythymidylate Kinase as a target in LKB1 Mutant Lung Cancer
2013
Abstract The LKB1/STK11 tumor suppressor encodes a serine/threonine kinase, which coordinates cell growth, polarity, motility, and metabolism. In non–small cell lung carcinoma, LKB1 is somatically inactivated in 25% to 30% of cases, often concurrently with activating KRAS mutations. Here, we used an integrative approach to define novel therapeutic targets in KRAS-driven LKB1-mutant lung cancers. High-throughput RNA interference screens in lung cancer cell lines from genetically engineered mouse models driven by activated KRAS with or without coincident Lkb1 deletion led to the identification of Dtymk, encoding deoxythymidylate kinase (DTYMK), which catalyzes dTTP biosynthesis, as synthetica…