Search results for "thyroid."

Il gozzo cervicomediastinico

2005

INTRODUCTION: Aim of the study is to discuss the diagnostic and therapeutic problems of substernal goiter (SG). MATERIALS AND METHODS: The Authors retrospectively analyzed 12 patients (3.1%) with substernal goiters among 379 patients undergoing surgical treatment for thyroid diseases from January 2000 to 2005, and evaluated the clinical data, preoperative diagnostic findings, surgical treatments, histopathological results, and postoperative complications. RESULTS: The most common symptoms were a cervical mass (100%) and dyspnea (16%), but 50% of the patients were asymptomatic. Chest radiography provided the first evidence of a substernal goiter in 100% of the patients. The AA performed tota…

Hypothyroidism and pregnancy. Situation in Latvia

2015

The thyroid gland is the first of the body's endocrine glands to develop, on approximately the 24 th day or 3-4 weeks of gestation, but at around 10-12 weeks the thyroid begins to function on its own. Thyroid hormones are involved in regulation of vital body function. In general normal development, growth and reproduction cannot occur without them. The normal function of thyroid gland is predictor to normal pregnancy outcome and foetus development. It is important to know how many women have hypothyroidism and what kind of treatment they receive. Author selected and made retrospective analysis of women with hypothyroidism maternity cases from 2010 to 2011 year. Data compared to the control …

Das Zellbild der Rattenhypophyse nach kombinierter Verabreichung einiger Thyreostatica zusammen mit SH-gruppenhaltigen Verbindungen unter besonderer …

1954

1. Es werden die Veranderungen des Zellbildes des Hypophysenvorderlappens der Ratte beschrieben, die sich nach Verabreichung thyreostatisch wirkender Stoffe ergeben. Diese Zustande werden mit den Zellbildern verglichen, die durch zusatzliche Gabe SH-gruppenhaltiger Verbindungen zu den gleichen Thyreostatica resultieren. 2. Es zeigte sich, das ein experimentell erzeugtes Wachstum der Glandula thyreoidea unabhangig von der Stoffwechselanderung verlaufen kann. 3. Stoffwechselanderung ist mit einer Alteration derβ-Zellen des Hypophysenvorderlappens verbunden. Dieβ-Zellen sind bei Thyroxinmangel vermehrt. 4. Kropfbildung geht mit einer Zunahme der Stammzellen einher, die vermehrtγ-Zellen bilden.…

Lebensqualität nach operativer Therapie des renalen Hyperparathyreoidismus. Ergebnisse einer prospektiven Langzeitstudie / Quality of Life After Oper…

2001

In einer prospektiven Langzeituntersuchung wurde die Lebensqualitat nach operativer Therapie des renalen Hyperparathyreoidismus untersucht. Vom 1.8.1987-31.8.2000 erfolgten 186 Eingriffe. Bevorzugte Operation war die totale Parathyreoidektomie mit autologer Epithelkorperchenreplantation. Die Erfolgsrate der erstmaligen Halsexploration betrug 98,2%. Juckreiz klang bei uber 60% der betroffenen Patienten innerhalb von 4 Wochen nach dem Eingriff ab. Die Ruckbildung ossarer Symptome bedurfte langerer Zeit. Ein Jahr postoperativ waren 75% der praoperativ von Juckreiz und 79% der vom ossaren Syndrom betroffenen Patienten asymptomatisch. Patienteneigene Risikofaktoren bedingen eine niedrige Letalit…

Endokrine Orbitopathie 1998

1998

Die haufigste extrathyreoidale Manifestation der autoimmunen Thyreopathie ist die endokrine Orbitopathie. Das Charakteristikum dieser Autoimmunerkrankung ist die entzundliche Volumenzunahme des peri- und retrobulbaren Gewebes, die zur klinischen Symptomatik nichtinfiltrativer Lidaffektionen, Protrusio bulbi, Augenmuskelparesen und bis hin zum Visusverlust fuhren kann. Die pathologischen Veranderungen der endokrinen Orbitopathie sind gekennzeichnet durch immunologisch vermittelte Entzundungsreaktionen im Retrobulbarraum, in deren Verlaufes zur lymphozytaren Infiltration und Einlagerung von Glykosaminoglykanen in das orbitale Muskel-, Binde- und Fettgewebe kommt. Trotz verschiedener neuer dia…

Parathyroid hormone and insulin-resistance in essential hypertension

2000

Thyroid disorders in polycystic ovary syndrome

2017

OBJECTIVE: Thyroid disorders, especially Hashimoto’s thyroiditis (HT), are observed significantly more often in patients with polycystic ovary syndrome (PCOS) than in the general population – approximately 27% and 8%, respectively. This is extremely important in young women, because both disorders are connected with fertility problems. As HT and PCOS occur together, fertility problems may become a serious clinical issue in these patients. MATERIALS AND METHODS: A systematic literature review in PubMed of PCOS- and HT-related articles in English, published until December 2015 was conducted. RESULTS: The reasons for joint prevalence still remain unclear. Genetic and autoimmune backgrounds are…

Resistance to thyroid hormones. Study of an affected kindred diagnosed at neonatal age

1998

Resistance to thyroid hormones (RTH) is a rare condition of reduced activity of thyroid hormones on peripheral tissues and/or reduced suppression of TSH secretion by thyroid hormones. The disease is characterised by high serum levels of T3, T4, fT3 and fT4, and by unexpectedly normal or high TSH levels. The origin of the resistance has been recognised in a thyroid hormone receptor deficit, whose gene (TRβ) has been mapped on chromosome 3p24.3 and several mutations have been identified. The clinical presentation may vary among a large spectrum from hypo-, to eu-, to hyperthyroidism in different patients, even in the same family. The diagnosis of RTH at birth and in the first months of life i…

Extranodal extension of nodal metastasis is the main prognostic moderator in squamous cell carcinoma of the esophagus after neoadjuvant chemoradiothe…

2017

Several studies, including comprehensive systematic reviews with meta-analyses of our group of research, have demonstrated the negative prognostic impact of the extranodal extension of nodal metastasis (ENE) in different cancer types, including squamous cell carcinoma (SCC) of the vulva, of the penis and of head and neck, as well as in tumors of the digestive and genitourinary systems, in thyroid cancer and others (1-17).

Immunosuppressant therapy of thyroid eye disease.

1988

Thyroid eye disease is attributed to an autoimmune process where both cellular and humoral immunity play a role. In this report, after a short introduction dealing with immunopathogenesis of the disease, immunosuppressant therapy is discussed. Treatment with glucocorticoids (as the standard substance), nonsteroid immunosuppressants (azathioprine, cyclophosphamide, lately cyclosporin) and with the immunomodulatory substance ciamexone is reviewed. Retroorbital irradiation as a "local" immunosuppressive method and plasmapheresis are also discussed. While systemic glucocorticoids and to a lesser extent orbital radiotherapy are routinely administered for severe Graves' ophthalmopathy, nonsteroid…