Search results for "tieteet"
showing 10 items of 379 documents
Quantifying and addressing the prevalence and bias of study designs in the environmental and social sciences
2020
Building trust in science and evidence-based decision-making depends heavily on the credibility of studies and their findings. Researchers employ many different study designs that vary in their risk of bias to evaluate the true effect of interventions or impacts. Here, we empirically quantify, on a large scale, the prevalence of different study designs and the magnitude of bias in their estimates. Randomised designs and controlled observational designs with pre-intervention sampling were used by just 23% of intervention studies in biodiversity conservation, and 36% of intervention studies in social science. We demonstrate, through pairwise within-study comparisons across 49 environmental da…
Safety of Novel Amino-5-laevulinate Photosensitizer Precursors in Photodynamic Therapy for Healthy Human Skin.
2015
Peer reviewed
GABA and Gap Junctions in the Development of Synchronized Activity in Human Pluripotent Stem Cell-Derived Neural Networks.
2017
The electrical activity of the brain arises from single neurons communicating with each other. However, how single neurons interact during early development to give rise to neural network activity remains poorly understood. We studied the emergence of synchronous neural activity in human pluripotent stem cell (hPSC)-derived neural networks simultaneously on a single-neuron level and network level. The contribution of gamma-aminobutyric acid (GABA) and gap junctions to the development of synchronous activity in hPSC-derived neural networks was studied with GABA agonist and antagonist and by blocking gap junctional communication, respectively. We characterized the dynamics of the network-wide…
Transcriptional Differences between Diapausing and Non-Diapausing D. montana Females Reared under the Same Photoperiod and Temperature
2016
Background A wide range of insects living at higher latitudes enter diapause at the end of the warm season, which increases their chances of survival through harsh winter conditions. In this study we used RNA sequencing to identify genes involved in adult reproductive diapause in a northern fly species, Drosophila montana. Both diapausing and non-diapausing flies were reared under a critical day length and temperature, where about half of the emerging females enter diapause enabling us to eliminate the effects of varying environmental conditions on gene expression patterns of the two types of female flies. Results RNA sequencing revealed large differences between gene expression patterns of…
Editorial : Networks Applied in Science Education Research
2020
Science education research is, in many ways, involved with exploring relational aspects of diverse elements that affect students’ learning outcomes; at one end, the elements may be concepts to be learned, and at the other end, the relations between students in different types of learning settings and environments and, ultimately, how such elements may interact [...]
Tracing the indexicalization of the notion "Helsinki s"
2017
AbstractEarlier research has concluded that there is a strong symbolic relationship between Helsinki as a place and non-standard /s/ pronunciation. This phenomenon is likewise in continuous evidence in the Finnish media and social media. The notion of “Helsinki s” has become a folk linguistic fact although it lacks a clear linguistic correlate or even status as a linguistic fact. The only sibilant of the Finnish language is officially a voiceless alveolar, while the “Helsinki s” is most often discussed as “hissing”, “sharp” or “fronted”. However, according to recent research based on listening tasks, any /s/ may be designated and discussed as a “Helsinki s” if the speaker is regarded as a H…
Korpusonomastinen tutkimus slanginimistä Hesa ja Stadi digitaalisissa diskursseissa
2019
Artikkelissamme selvitämme Helsinkiä tarkoittavien slanginimien, Hesan ja Stadin, käyttöä uudentyyppisen aineiston ja menetelmän avulla. Aiemmissa näitä nimiä koskevissa tutkimuksissa lähtökohta on ollut kvalitatiivinen, mutta tässä tutkimuksessa lähdemme liikkeelle laajasta digitaalisesta aineistosta ja tilastollisista menetelmistä. Tutkimuksemme on uusi avaus nimistöntutkimuksessa, ja nimitämme sitä korpusavusteiseksi nimistöntutkimukseksi, lyhyemmin korpusonomastiikaksi.
 Aineistonamme on laaja Suomi24-keskustelufoorumista muodostettu ja Kielipankista saatava Suomi24-korpus, josta olemme hakeneet Hesa- ja Stadi-nimet. Tutkimus toteutetaan korpusavusteisena diskurssintutkimuksena. Mo…
Taloustieteilijöiden harjoittelijavaihdosta poikkitieteelliseen johtajuuteen : AIESEC Jyväskylä 1969-2009
2014
Pro gradu -työni on toimeksiantona tehty AIESEC Jyväskylän 40-vuotishistoria. Järjestön historiaa tarkastellaan arkistolähteiden ja alumnien haastattelujen pohjalta. AIESEC perustettiin 1948 rauhanaatteen pohjalle luomaan ymmärrystä kulttuurien välille kansainvälisen harjoitteluvaihdon avulla. AIESEC Jyväskylä perustettiin 1969 osaksi Jyväskylän yliopiston taloustieteiden ainejärjestöä Pörssi ry:tä, ja sen toiminta oli suunnattu taloustieteilijöille. Toiminta koostui harjoittelupaikkojen hankinnasta paikallisiin yrityksiin, ulkomailta tulleiden harjoittelijoiden vastaanottamisesta ja kesäohjelman järjestämisestä saapuville harjoittelijoille. Heikosti kansainvälistyneessä Keski-Suomessa järj…