Search results for "time factor"

showing 10 items of 3219 documents

Predictors of early scaffold thrombosis: results from the multicenter prospective German-Austrian ABSORB RegIstRy.

2018

BACKGROUND In randomized clinical trials, the risk of thrombotic events with the absorb bioresorbable vascular scaffold (BVS) was significantly higher than with metallic drug-eluting stents. We evaluated predictors of scaffold thrombosis in the large-scale, multicenter German-Austrian ABSORB RegIstRy. METHODS AND RESULTS 3178 patients with treatment of 4252 lesions using 5020 scaffolds were included. Follow-up rate at 6 months was 97.4%. Forty-five (1.42%) patients experienced definite/probable scaffold thrombosis during follow-up. Multiple regression analysis showed implantation of absorb BVS in bifurcation lesions [odds ratio (OR): 4.43; 95% confidence interval (CI): 1.69-11.59; P=0.0024]…

Target lesionMalemedicine.medical_specialtyTime Factorsmedicine.medical_treatmentClinical Decision-MakingCoronary Artery Disease030204 cardiovascular system & hematologyRevascularizationRisk Assessment03 medical and health sciences0302 clinical medicinePercutaneous Coronary InterventionRisk FactorsGermanyAbsorbable ImplantsMedicineHumans030212 general & internal medicineMyocardial infarctionProspective StudiesRegistriesAgedbusiness.industryIncidence (epidemiology)Coronary ThrombosisPatient SelectionGeneral MedicineOdds ratioMiddle AgedDebulkingmedicine.diseaseThrombosisConfidence intervalSurgeryTreatment OutcomeAustriaFemaleCardiology and Cardiovascular MedicinebusinessCoronary artery disease
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Everolimus eluting bioresorbable vascular scaffolds in patients with acute coronary syndromes: Two‐year results from the German‐Austrian ABSORB regis…

2021

Abstract Objectives To identify potential differences in 2‐year outcome between patients who underwent coronary revascularization using bioresorbable vascular scafffolds (BVS) in stable coronary artery disease (CAD) and acute coronary syndromes (ACS). Background Data from randomized trials suggest a significantly higher event rate following coronary revascularization using everolimus‐eluting BVS as compared to new generation drug eluting stents. Whether particular patient subgroups are at increased risk for scaffold thrombosis and target lesion failure (TLF) has not clearly been demonstrated. Methods German‐Austrian ABSORB RegIstRy is a prospective all‐comer multi‐center observational study…

Target lesionmedicine.medical_specialtyTime FactorsMedizinCoronary Artery Disease030204 cardiovascular system & hematologyProsthesis Designlaw.inventionCoronary artery disease03 medical and health sciencesPercutaneous Coronary Intervention0302 clinical medicineRandomized controlled triallawInternal medicineAbsorbable ImplantsmedicineHumansRadiology Nuclear Medicine and imagingIn patientEverolimusProspective StudiesRegistries030212 general & internal medicineddc:610Acute Coronary SyndromeEverolimusbusiness.industryGeneral Medicinemedicine.diseaseThrombosisStenosisTreatment OutcomeAustriaCardiologyCardiology and Cardiovascular MedicinebusinessMacemedicine.drug
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Fat and salt contents affect the in-mouth temporal sodium release and saltiness perception of chicken sausages

2013

In cooked meats, sodium chloride is involved in taste, texture and flavour release. So a reduction in the salt content may have an impact on overall perception and acceptability. The aim of this study was to evaluate the influence of composition on sodium release and saltiness intensity in chicken sausages. The rheological properties of the sausages differed according to composition. Temporal sodium release and temporal saltiness intensity were evaluated by four selected subjects when eating sausages. At each time point, the effect of the salt level in sausages on sodium release was positive and highly significant. The effect of lipids on sodium release was negative. Concerning perception, …

TasteTime FactorsSalt contentSodiumFlavourchemistry.chemical_elementSalt (chemistry)Sodium ChlorideFood Preferences0404 agricultural biotechnologyAnimalsFood sciencePoultry ProductsComputingMilieux_MISCELLANEOUSchemistry.chemical_classificationSodium0402 animal and dairy science04 agricultural and veterinary sciencesConsumer BehaviorDietary Fats040401 food science040201 dairy & animal sciencechemistryTasteComposition (visual arts)Chickens[SDV.AEN]Life Sciences [q-bio]/Food and NutritionFood Science
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Frequency distribution of journalistic attention for scientific studies and scientific sources: An input-output analysis.

2020

Based on the decision-theoretical conditions underlying the selection of events for news coverage in science journalism, this article uses a novel input-output analysis to investigate which of the more than eight million scientific study results published between August 2014 and July 2018 have been selected by global journalism to a relevant degree. We are interested in two different structures in the media coverage of scientific results. Firstly, the structure of sources that journalists use, i.e. scientific journals, and secondly, the congruence of the journalistic selection of single results. Previous research suggests that the selection of sources and results follows a certain heavy-tai…

TechnologyTime FactorsMedical JournalsScienceJournalismDecision MakingSocial SciencesResearch and Analysis MethodsCognitionSociologyMedicine and Health SciencesPsychologyMass MediaSocial ChangeScientific PublishingLikelihood FunctionsAltmetricsSocial ResearchResearchQRCognitive PsychologyBiology and Life SciencesResearch AssessmentProbability TheoryCommunicationsBibliometricsPhysical SciencesMedicineCognitive SciencePeriodicals as Topicddc:600Medical HumanitiesMathematicsResearch ArticleNeuroscienceStatistical DistributionsPloS one
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Glutathione regulates telomerase activity in 3T3 fibroblasts.

2004

Changes in telomerase activity have been associated either with cancer, when activity is increased, or with cell cycle arrest when it is decreased. We report that glutathione, a physiological antioxidant present at high intracellular concentrations, regulates telomerase activity in cells in culture. Telomerase activity increases in 3T3 fibroblasts before exponential cell growth. The peak of telomerase activity takes place 24 h after plating and coincides with the maximum levels of glutathione in the cells. When cells are treated with buthionine sulfoximine, which decreases glutathione levels in cells, telomerase activity decreases by 60%, and cell growth is delayed. Glutathione depletion in…

TelomeraseAntioxidantCell cycle checkpointTime FactorsCell divisionmedicine.medical_treatmentBlotting WesternImmunoblottingE2F4 Transcription FactorBiochemistryGene Expression Regulation Enzymologicchemistry.chemical_compoundMicemedicineAnimalsButhionine sulfoximineColoring AgentsMolecular BiologyButhionine SulfoximineTelomeraseInhibitor of Differentiation Protein 2Cell growthCell CycleCell BiologyGlutathione3T3 CellsTrypan BlueCell cycleFibroblastsFlow CytometryMolecular biologyGlutathioneDNA-Binding ProteinsRepressor ProteinschemistryOxidation-ReductionCell DivisionTranscription FactorsThe Journal of biological chemistry
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Changes of the hindgut microbiota due to high-starch diet can be associated with behavioral stress response in horses.

2015

6 pages; International audience; The digestive system of horses is adapted to a high-fiber diet consumed in small amounts over a long time. However, during training, high-starch and low-fiber diets are usually fed which may induce hindgut microbial disturbances and intestinal pain. These diets can be described as alimentary stress. The aim of the present study was to investigate to what extent changes in behavior are associated with alimentary stress and microbial composition changes of the cecal or colonic ecosystem. Six fistulated horses were used. The alimentary stress was a modification of diet from a high-fiber diet (100% hay) to a progressive low-fiber and high-starch diet (from 90% h…

Time Factors040301 veterinary sciencesmedia_common.quotation_subjectExperimental and Cognitive PsychologyBiology0403 veterinary scienceBehavioral NeuroscienceHorse behaviormedicine[ SDV.EE.IEO ] Life Sciences [q-bio]/Ecology environment/SymbiosisDietary CarbohydratesIntestinal FistulaAnimalsAlimentary stressFood scienceCastrationLongitudinal StudiesHorsesSocial BehaviorCecummedia_common2. Zero hunger[ SDE.BE ] Environmental Sciences/Biodiversity and EcologyAnalysis of VarianceBehaviorMicrobiotaNeophobia0402 animal and dairy scienceHorseHindgutStarch04 agricultural and veterinary sciencesFeeding Behaviormedicine.disease040201 dairy & animal scienceBlood Cell CountDietHayExploratory BehaviorAnaerobic bacteria[SDE.BE]Environmental Sciences/Biodiversity and EcologyAnaerobic exerciseStress PsychologicalVigilance (psychology)[SDV.EE.IEO]Life Sciences [q-bio]/Ecology environment/Symbiosis
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Joint associations of accelerometer-measured physical activity and sedentary time with all-cause mortality: a harmonised meta-analysis in more than 4…

2020

Funder: National Institute for Health Research (NIHR) Collaboration for Leadership in Applied Health Research and Care East Midlands

Time Factors2314educationPhysical activityPhysical Therapy Sports Therapy and RehabilitationsedentarydeathAccelerometryCox proportional hazards regressionHumansMedicineOrthopedics and Sports Medicine1506Prospective cohort study1507Exercisehealth care economics and organizationsAgedSedentary timeMortality Prematurebusiness.industryOriginal researchMortality rateGeneral MedicineMiddle AgedVDP::Medisinske Fag: 700::Idrettsmedisinske fag: 850Peer reviewmeta-analysisaccelerometerMeta-analysisSedentary BehaviorbusinessAll cause mortalityDemographyBritish Journal of Sports Medicine
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In vivo and in vitro degradation of a novel bioactive guided tissue regeneration membrane

2006

The aim of this study was to assess degradation of a novel bioactive guided tissue regeneration (GTR) membrane and to quantify the concurrent tissue responses. Pieces of membrane composed of poly-l-lactide, poly-d,l-lactide, trimethylenecarbonate and polyglycolide were dipped into an N-methyl-2-pyrroline (NMP) solution and implanted in the mandibles of 10 sheep. The animals were sacrificed at 6-104 weeks. Parallel in vitro degradation was analysed by measuring the inherent viscosity, water absorption and remaining mass. One of the 2 in vitro sets of membranes was prehandled with NMP. At 6-26 weeks in vivo, the gradually more degraded implants were surrounded by a fibrous network. At 52 and …

Time FactorsAbsorption of waterPolyglycolideInherent viscosityBiocompatible MaterialsMandiblechemistry.chemical_compoundIn vivoAnimalsMedicineDental ImplantsSheepbusiness.industryRegeneration (biology)Dental Implantation EndosseousMembranes ArtificialAnatomyIn vitroBiodegradation EnvironmentalMembraneOtorhinolaryngologychemistryGuided Tissue Regeneration PeriodontalBiophysicsDegradation (geology)FemaleSurgeryOral SurgerybusinessInternational Journal of Oral and Maxillofacial Surgery
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A study of electron transfer in Ru(dcbpy)2(NCS)2 sensitized nanocrystalline TiO2 and SnO2 films induced by red-wing excitation.

2008

Excited state dynamics and electron transfer from the Ru(dcbpy)2(NCS)2 (RuN3) sensitizer to semiconductor nanoparticles were studied using time-resolved femtosecond absorption spectroscopy. We found that excitation of the red wing of the absorption spectrum of the sensitizer populates the (3)MLCT state directly, both in solution and attached on semiconductor nanoparticle films. Electron injection is slowed down and becomes gradually less efficient as excitation moves towards red from the absorption maximum at 535 nm. At 675 nm the injection is non-exponential and characterized by 5, 30 and 180 ps time constants. The non-exponential electron injection observed is assigned to injection from a…

Time FactorsAbsorption spectroscopyPhotochemistrySurface PropertiesAnalytical chemistryGeneral Physics and AstronomyElectronsSensitivity and SpecificityRutheniumElectron transferOrganometallic CompoundsPhysical and Theoretical ChemistryTriplet stateAbsorption (electromagnetic radiation)Coloring AgentsTitaniumChemistrybusiness.industryLasersSpectrum AnalysisTin CompoundsMembranes ArtificialNanocrystalline materialNanostructuresKineticsSemiconductorSemiconductorsExcited stateFemtosecondbusinessThiocyanatesPhysical chemistry chemical physics : PCCP
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Pigment organization and energy transfer dynamics in isolated photosystem I (PSI) complexes from Arabidopsis thaliana depleted of the PSI-G, PSI-K, P…

2002

Abstract Green plant photosystem I (PSI) consists of at least 18 different protein subunits. The roles of some of these protein subunits are not well known, in particular those that do not occur in the well characterized PSI complexes from cyanobacteria. We investigated the spectroscopic properties and excited-state dynamics of isolated PSI-200 particles from wild-type and mutant Arabidopsis thaliana plants devoid of the PSI-G, PSI-K, PSI-L, or PSI-N subunit. Pigment analysis and a comparison of the 5K absorption spectra of the various particles suggests that the PSI-L and PSI-H subunits together bind approximately five chlorophyll a molecules with absorption maxima near 688 and 667nm, that…

Time FactorsAbsorption spectroscopyProtein subunitPhotosynthetic Reaction Center Complex ProteinsArabidopsisLight-Harvesting Protein ComplexesBiophysicsBiologyPhotosystem Ichemistry.chemical_compoundPhase (matter)MoleculePlant ProteinsQuantitative Biology::BiomoleculesPhotosystem I Protein ComplexTemperaturePigments Biologicalbeta CaroteneFluorescenceKineticsCrystallographySpectrometry FluorescenceEnergy TransferchemistryChlorophyllThermodynamicsHigh Energy Physics::ExperimentAbsorption (chemistry)Research Article
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