Search results for "tips"

PM441. Long term atypical antipsychotic treatment improves cognitive performance in schizophrenia but not surpassing conventional antipsychotic drugs…

2016

Amisulpride versus flupentixol in schizophrenia with predominantly positive symptomatology - a double-blind controlled study comparing a selective D …

1998

The benzamide amisulpride (ASP) is a selective D2-like dopamine antagonist, while flupentixol (FPX), a thioxanthene, blocks D2-like, D1-like and 5-HT2 receptors. To evaluate efficacy and safety of ASP and to investigate the importance of an additional D1-like antagonism for antipsychotic effects and extrapyramidal tolerability, a randomized double-blind multi-center study versus FPX as reference drug was performed for 6 weeks in 132 patients suffering from acute schizophrenia (DSM-III-R) with predominant positive symptomatology. Doses were initially fixed (ASP: 1000 mg/day; FPX: 25 mg/day) but could be reduced by 40% in case of side effects (mean daily doses: ASP: 956 mg; FPX: 22.6 mg). Int…

Pielāgots mācību saturs pirmsskolā 5 - 7 gadu vecu bērnu uztveres tipam

2019

Darba nosaukums: „Pielāgots mācību saturs pirmsskolā 5 -7 gadu vecu bērna uztveres tipam” Darba aktualitāte: Mūsdienu laikmets pieprasa, lai ikviens būtu maksimāli zinošs un kompetents, tai skaitā, bērns savā attīstībā. Zinot cilvēka fiziskās, psiholoģiskās rakstura iezīmes, speciālisti ir nonākuši pie secinājuma, ka katram bērnam raksturīgs noteikts uztveres tips. Pielietojot „pareizās” metodes un pielāgojot mācību procesu bērnu uztvers tipam, iespējams efektīvāk stimulēt bērnu piedalīties mācību procesā, gūt labākus rezultātus. Darba mērķis: teorētiski izzināt un praktiski izpētīt vai 5 - 7 gadus vecu bērnu uztveres tipam pielāgots mācību saturs motivē to labprātāk un efektīvāk apgūt jaun…

Presynaptic regulation of the electrically evoked release of endogenous dopamine from the isolated neurointermediate lobe or isolated neural lobe of …

1988

Isolated neurointermediate lobes (NILs) or isolated neural lobes (NLs) of the rat pituitary gland were incubated in Krebs-HEPES solution which contained pargyline and the dopamine uptake inhibitor GBR 12921. The release of endogenous dopamine was determined by HPLC with electrochemical detection. Electrical stimulation of the pituitary stalk induced a frequency-dependent release of dopamine. The release of dopamine from the combined NIL evoked by stimulation at 15 Hz was increased by 130% in the presence of the dopamine D2 receptor antagonist, (-)-sulpiride; the (+)-enantiomer of sulpiride had virtually no effect. When the stimulation frequency was 3 Hz (-)-sulpiride caused an increase in d…

Kultūras centra "Ulbrokas pērle" tīmekļa vietnes prototipa projektēšana pielietojot vizuālā dizaina izstrādes programmatūru

2022

Darba autors: Niks Teodors Pinnis. Darba nosaukums: Kultūras centra “Ulbrokas Pērle” tīmekļa vietnes prototipa projektēšana, pielietojot vizuālā dizaina izstrādes programmatūru. Darba mērķis: Izpētīt kultūras centrā “Ulbrokas pērle” izmantotās Informācijas Sistēmas un to izmantošanas nepieciešamību, noskaidrot kultūras centra darbības virzienu un nepieciešamību pēc Informācijas Sistēmu optimizācijas, kā arī izveidot kultūras centra tīmekļa vietnes prototipu, pielietojot vizuālā dizaina izstrādes programmatūru. Pētījuma daļā tika daļēji izstrādāts kultūras centra “Ulbrokas Pērle” tīmekļa vietnes prototips, kā arī tika izmantota kvalitatīvā metode aptaujām, lai noskaidrotu, kas nepieciešams v…

USO DI TECNICHE AVANZATE PER LA OTTIMIZZAZIONE STRUTTURALE E FUNZIONALE DI SCAFFOLD COMPOSITI POLIMERO-CARICA INORGANICA PER LA RIGENERAZIONE OSSEA.

2020

Cost-effectiveness of psychotropic polypharmacy in routine schizophrenia care. Results of the ELAN prospective observational trial

2018

Abstract Aims To analyse the costs and cost-effectiveness of psychotropic polypharmacy in comparison to antipsychotic monotherapy in patients with schizophrenia and schizo-affective disorder under real-world treatment conditions. Methods A prospective observational study including 374 adult psychiatric in-patients with schizophrenia or schizo-affective disorder was conducted. Psychotropic regimen, clinical outcomes, and quality of life were assessed before discharge and after 6, 12, 18, and 24 months. Costs and outcomes of psychotropic polypharmacy in comparison to antipsychotic monotherapy were analysed by means of mixed-effects regression models adjusted for propensity scores. Net-benefit…

Tailoring PLLA scaffolds for tissue engineering applications: Morphologies for 2D and 3D cell cultures

2009

PLLA scaffold suitable for dermis regeneration were realized by Thermally Induced Phase Separation (TIPS) starting from a ternary solution PLLA/dioxane/water. The reconstruction of a complex tissues as the dermis implies the use of different cellular types (coculture), with different growth behaviour (2D vs. 3D). The scaffolds present an homogeneous porous surface to allow the keratinocytes 2D growth and a porous internal structure for the fibroblasts 3D growth. Our results show that the porosity of the surface can be tuned by changing the chemical nature of the sample holder (aluminium, teflon, polypropylene). A large variety of morphologies, in terms of average pore size and interconnecti…

Thomas S. Szasz, precursor de la psiquiatría crítica

2015

Thomas S. Szasz (1920-2012), profesor de psiquiatría de la State University of New York en Siracusa (EE. UU.), fue el mayor crítico del cientificismo y de las prácticas coercitivas de la psiquiatría. Con treinta y cinco libros publicados y centenares de artículos, no ha existido otro autor más prolífico en su campo. Fue un intelectual de primer orden que realizó uno de los más lúcidos análisis conceptuales y epistemológicos de la psiquiatría. Este le sirvió de base para sostener su crítica abierta a los abusos de poder de la psiquiatría (encierros involuntarios, tratamientos no consentidos, etc.). Su libro de 1961 El mito de la enfermedad mental es un clásico. En él Szasz sostuvo, contra el…

The Role of Attitudes Toward Medication and Treatment Adherence in the Clinical Response to LAIs: Findings From the STAR Network Depot Study

2021

Background: Long-acting injectable (LAI) antipsychotics are efficacious in managing psychotic symptoms in people affected by severe mental disorders, such as schizophrenia and bipolar disorder. The present study aimed to investigate whether attitude toward treatment and treatment adherence represent predictors of symptoms changes over time.Methods: The STAR Network “Depot Study” was a naturalistic, multicenter, observational, prospective study that enrolled people initiating a LAI without restrictions on diagnosis, clinical severity or setting. Participants from 32 Italian centers were assessed at three time points: baseline, 6-month, and 12-month follow-up. Psychopathological symptoms, att…