Search results for "tmor"
showing 7 items of 137 documents
Determination of Death in Execution by Lethal Injection in China.
2018
Abstract:Since 1997, execution in China has been increasingly performed by lethal injection. The current criteria for determination of death for execution by lethal injection (cessation of heartbeat, cessation of respiration, and dilated pupils) neither conform to current medical science nor to any standard of medical ethics. In practice, death is pronounced in China within tens of seconds after starting the lethal injection. At this stage, however, neither the common criteria for cardiopulmonary death (irreversible cessation of heartbeat and breathing) nor that of brain death (irreversible cessation of brain functions) have been met. To declare a still-living person dead is incompatible wi…
Imaging for Ballistic Trauma: Other Applications of Forensic Imaging in the Living
2019
Firearms are mechanical instruments that allow launching remote specific bodies with mass (bullets) exploiting burst gas energy. The role of imaging for ballistic trauma is crucial in order to define the main characteristics for both judiciary and nonjudiciary purpose, which are the intracorporeal trajectory, the entrance and exit wounds, and the general characteristics of gunshot injuries.
Computed Tomography in Brain Tumors
1981
Craniocerebral injury and brain tumor are the two most important indications for CT studies. There is unanimous agreement that computed tomography is unequalled in its diagnostic accuracy in demonstration of intracranial tumors. Our own experience is based on observations in 3,750 patients with brain tumors or cerebral metastases who were studied in the period from December 1974 to March 1980 (Table 1). Initial CT studies demonstrated the intracranial tumor or tumors in 3,589 cases (95.7%). Several CT examinations were necessary for diagnosis of a brain tumor in 112 patients (3.0%). Other diagnostic procedures or postmortem studies revealed a brain tumor which had not been demonstrated with…
Radiology for Postmortem
2019
Thanatology deals with the study of early and postmortem changes in relation to the estimation of the time since death. These normal postmortem changes depend on internal and external factors, such as body temperature, preexisting conditions, underlying disease or injury, and the postmortem interval.
COVID-19 Deaths: Are We Sure It Is Pneumonia? Please, Autopsy, Autopsy, Autopsy!
2020
The current outbreak of COVID-19 severe respiratory disease, which started in Wuhan, China, is an ongoing challenge, and a major threat to public health that requires surveillance, prompt diagnosis, and research efforts to understand this emergent pathogen and to develop an effective response. Due to the scientific community’s efforts, there is an increasing body of published studies describing the virus’ biology, its transmission and diagnosis, its clinical features, its radiological findings, and the development of candidate therapeutics and vaccines. Despite the decline in postmortem examination rate, autopsy remains the gold standard to determine why and how death ha…
Postmortem Electrical Conductivity Changes of Dicentrarchus labrax Skeletal Muscle: Root Mean Square (RMS) Parameter in Estimating Time since Death
2022
Electric impedance spectroscopy techniques have been widely employed to study basic biological processes, and recently explored to estimate postmortem interval (PMI). However, the most-relevant parameter to approximate PMI has not been recognized so far. This study investigated electrical conductivity changes in muscle of 18 sea bass specimens, maintained at different room temperatures (15.0 °C; 20.0 °C; 25.0 °C), during a 24 h postmortem period using an oscilloscope coupled with a signal generator, as innovative technology. The root mean square (RMS) was selected among all measured parameters, and recorded every 15 min for 24 h after death. The RMS(t) time series for each anima…
Differential effects of oncogenic H- and K-ras expression on HT-29 colorectal carcinoma cell line.
2008
The Ras oncogene is mutated in about 30% of the human tumors and its mutations are always point mutations concerning codon 12, 13 and 61. These mutations cause in the proteins a reduced GTPase activity, so that they become constitutively active. In human cells there are three main isoforms of Ras (H, K, N-ras) which can trigger alternative pathways of signal trasduction. In order to investigate the effects of expression of different oncogenic Ras isoforms in colorectal carcinoma cells (HT-29), we obtained stable clones of HT-29 cells transfected with cDNAs codifying H-RasG12V and K-Ras G12V called respectively H12 and K12 and K-RasG13D called K13, under the control of an hormone-inducible p…