Search results for "tolerance"

showing 10 items of 956 documents

Inhibition of the mixed lymphocyte reaction by T cell vaccination

1990

Immunization with attenuated activated autoreactive T cell lines and clones induces a response in syngeneic animals which can induce protection or recovery from autoimmune disease. This process has been termed T cell vaccination. The aim of the present study was to investigate the effect of immunization with MHC-reactive T cells on the mixed lymphocyte reaction (MLR). By injecting attenuated activated T cells primed for an alloantigen, we markedly reduced the MLR in both rats and mice. This depression appeared to be mediated by active suppression; lymphoid cells from T cell-vaccinated animals suppressed the MLR responsiveness of T cells from naive animals. Suppression of the MLR was not res…

Encephalomyelitis Autoimmune ExperimentalT-LymphocytesT cellImmunologyReceptors Antigen T-CellT-cell vaccinationMice Inbred Strainschemical and pharmacologic phenomenaBiologyLymphocyte ActivationImmunotherapy AdoptiveMiceInterleukin 21Immune TolerancemedicineAnimalsImmunology and AllergyCytotoxic T cellIL-2 receptorAntigen-presenting cellfungiRats Inbred Strainshemic and immune systemsT lymphocyteNatural killer T cellRatsmedicine.anatomical_structureImmunologyFemaleLymphocyte Culture Test MixedEuropean Journal of Immunology
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Immunoregulation: studies of physiological and therapeutic autoreactivity by T cell vaccination

1992

Encephalomyelitis Autoimmune Experimentalbusiness.industryT-LymphocytesEncephalomyelitismedicine.medical_treatmentVaccinationImmunologyT-cell vaccinationAutoimmunityGeneral MedicineT lymphocyteImmunotherapymedicine.diseasemedicine.disease_causeAutoimmunityImmune toleranceVaccinationImmunopathologyImmunologyImmune TolerancemedicineAnimalsHumansImmunotherapybusinessSpringer Seminars in Immunopathology
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Impaired glucose regulation, depressive symptoms, and health-related quality of life

2020

IntroductionThis study aims to investigate whether the associations between impaired glucose regulation and health-related quality of life are modified by severity or type of depressive symptoms.Research design and methodsFor this cross-sectional study, we included 1939 individuals (mean age 61.5 years) from the Helsinki Birth Cohort Study. Between 2001 and 2004, a standard 2-hour 75 g oral glucose tolerance test was applied to define normoglycemia, pre-diabetes, and newly diagnosed diabetes. Information on previously diagnosed diabetes was collected from national registers and questionnaires. Pre-diabetes was defined as having either impaired fasting glucose or impaired glucose tolerance. …

Endocrinology Diabetes and MetabolismelämänlaatuPsychosocial ResearchCohort StudiesImpaired glucose tolerancehenkinen hyvinvointi0302 clinical medicineQuality of lifeinsulin resistanceMedicine18661506030212 general & internal medicineDepression (differential diagnoses)POPULATIONMETABOLIC SYNDROMERISKeducation.field_of_studyCOMPLICATIONSDepressionASSOCIATIONMiddle Agedkeski-ikäiset3. Good healthPREVALENCEtype 2INVENTORY-IIdepressiondiabetes mellitusikääntyneetmasennusmedicine.medical_specialtyPopulationDiseases of the endocrine glands. Clinical endocrinology03 medical and health sciencesInsulin resistanceInternal medicineDiabetes mellitusHumanseducationbusiness.industryDIABETES-MELLITUSinsuliiniresistenssimedicine.diseaseImpaired fasting glucoseRC648-665Cross-Sectional StudiesGlucosePSYCHOMETRIC PROPERTIESquality of life3121 General medicine internal medicine and other clinical medicineMetabolic syndromebusinessfyysinen hyvinvointiaikuistyypin diabetes030217 neurology & neurosurgeryBMJ Open Diabetes Research & Care
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Fault Tolerant Ancillary Function of Power Converters in Distributed Generation Power System within a Microgrid Structure

2013

Distributed generation (DG) is deeply changing the existing distribution networks which become very sophisticated and complex incorporating both active and passive equipment. The simplification of their management can be obtained assuming a structure with small networks, namely, microgrids, reproducing, in a smaller scale, the structure of large networks including production, transmission, and distribution of the electrical energy. Power converters in distributed generation systems carry on some different ancillary functions as, for example, grid synchronization, islanding detection, fault ride through, and so on. In view of an optimal utilization of the generated electrical power, fault to…

EngineeringArticle Subjectbusiness.industryControl engineeringFault toleranceSettore ING-IND/32 - Convertitori Macchine E Azionamenti ElettriciFault (power engineering)Power Converters Fault Tolerant Distributed Generation MicrogridsStuck-at faultElectric power systemDistributed generationElectronic engineeringIslandingElectric powerMicrogridElectrical and Electronic Engineeringbusiness
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Application of Neural Networks and Expert Systems in a hierarchical approach to the intelligent greenhouse control

2003

A novelty methodology based on the hierarchical combination of neural networks and expert systems is proposed in a centralized approach for the intelligent greenhouse control. The knowledge-based system is in charge of carrying out the determination of PH land value, composition, carbonic anhydride artificial atmosphere, external and internal temperature, wind and humidity measurements. From the results obtained, and by means of a neural network developed and trained for this application, the land quality is evaluated. On the other hand, the expert system, apart from supervising the system function and implementing fault tolerance mechanisms, performs the opportune actions in function of th…

EngineeringAtmosphere (unit)Artificial neural networkbusiness.industrymedia_common.quotation_subjectControl (management)GreenhouseFault toleranceControl engineeringcomputer.software_genreExpert systemQuality (business)businessFunction (engineering)computermedia_common
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Experimental validation of a general model for three phase inverters operating in healthy and faulty modes

2012

The paper presents the experimental verification of a general mathematical model of Voltage Source Inverters (VSI) able to simulate fault conditions and which is also useful for the simulation of fault-tolerant systems for different applications. In general, in the past, the problem of faulty inverters modeling has been addressed specifically by considering faults on the different phases as separate cases. Furthermore, traditional models include only the faulty mode and not the healthy mode, so resulting then not able to predict transient phenomena. The model hereafter presented overcomes this drawback. It was formulated by introducing the concept of “healthy leg binary variables”. Such var…

EngineeringCorrectnessCircuit faults Fault tolerance Fault tolerant systems Integrated circuit modeling Inverters Mathematical model Vectorsbusiness.industryFault toleranceControl engineeringHardware_PERFORMANCEANDRELIABILITYSettore ING-IND/32 - Convertitori Macchine E Azionamenti ElettriciFault (power engineering)Fault indicatorStuck-at faultComputer Science::Hardware ArchitectureThree-phaseTransient (oscillation)Voltage sourcebusinessComputer Science::Operating SystemsComputer Science::Distributed Parallel and Cluster ComputingInternational Symposium on Power Electronics Power Electronics, Electrical Drives, Automation and Motion
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The effect of manufacturing tolerances on a tubular linear ferrite motor

2015

This study presents a numerical and experimental study on the effect of permanent magnet tolerances on the performances of a Tubular Linear Ferrite Motor. The statistical distribution of the magnetic characteristic of a set of commercial magnets is obtained experimentally while the performances of a the tubular motor are numerically evaluated. The performances that have been considered are: cogging force, end effect force and generated thrust. It has been shown that: 1)the statistical variability of the magnets modifies the time behavior of the cogging force; 2)the value of both the end effect cogging force and the generated thrust are directly linked to the values of then remanence field o…

EngineeringFinite element methodManufacturing toleranceSettore ING-IND/11 - Fisica Tecnica AmbientaleMagnetic domainbusiness.industryElectrical engineeringMechanical engineeringThrustTubular Linear Ferrite MotorCogging torqueSettore ING-IND/32 - Convertitori Macchine E Azionamenti ElettriciForgingMagnetic fluxIndustrial and Manufacturing EngineeringRemanenceMagnetSliderFerrite (magnet)Electrical and Electronic Engineeringbusiness
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Manufacturing tolerances effects on PV array energy production

2014

This paper investigates the tolerance effects of commercial photovoltaic modules in terms of electrical energy reduction of photovoltaic plants. Several commercial modules, having the same rated power, present different power tolerance values. A wide tolerance is an indicator of possible defects or differences in the production process and is responsible of remarkable reductions in the electricity production of photovoltaic plants. In this paper, thanks to the development of a suitable simulation tool, several simulations have been carried out, considering different tolerance and shading conditions for the PV array. Simulation results quantify the peak power value of the different plant con…

EngineeringI-V characteristicManufacturing toleranceEquationbusiness.industryElectric potential energyPhotovoltaic systemPV module defectArrayProductionSettore ING-IND/32 - Convertitori Macchine E Azionamenti ElettriciAutomotive engineeringStandardPower ratingElectricity generationMathematical modelElectronic engineeringGrid-connected photovoltaic power systemRooftop photovoltaic power stationbusinessmismatchPhotovoltaic systemNominal power (photovoltaic)
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Robust Control Allocation for Spacecraft Attitude Stabilization under Actuator Faults and Uncertainty

2014

A robust control allocation scheme is developed for rigid spacecraft attitude stabilization in the presence of actuator partial loss fault, actuator failure, and actuator misalignment. First, a neural network fault detection scheme is proposed, Second, an adaptive attitude tracking strategy is employed which can realize fault tolerance control under the actuator partial loss and actuator failure withinλmin⁡=0.5. The attitude tracking and faults detection are always here during the procedure. Once the fault occurred which could not guaranteed the attitude stable for 30 s, the robust control allocation strategy is generated automatically. The robust control allocation compensates the control …

EngineeringSpacecraftArtificial neural networkArticle Subjectbusiness.industryGeneral Mathematicslcsh:MathematicsVDP::Technology: 500::Mechanical engineering: 570General EngineeringControl engineeringFault tolerancelcsh:QA1-939Fault detection and isolationComputer Science::RoboticsSylvester's law of inertiaEngineering (all)Robustness (computer science)Control theorylcsh:TA1-2040Mathematics (all)Robust controlbusinessActuatorlcsh:Engineering (General). Civil engineering (General)Mathematics (all); Engineering (all)Mathematical Problems in Engineering
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Controlled Fault-Tolerant Power Converters for Power Quality Enhancement

2013

Power quality depends generally on the interaction of electrical power with electrical equipments. If electrical equipments operate correctly and reliably without being damaged or stressed, a suitable level of power quality is assured. On the other hand, if the electrical equipment malfunctions, is unreliable, or is damaged during normal usage, power quality is poor and probably the economical loss could be important like the technical one. In the scenario of the Distributed Generation, power quality issues will be moreover important because an higher dissemination of power conditioning equipment will be requested and this obviously increases the sources of vulnerability of the electrical s…

EngineeringSwitched-mode power supplypower supply qualitypower system controlSettore ING-IND/32 - Convertitori Macchine E Azionamenti ElettriciPower budgetpower quality enhancementTopologyMaximum power point trackingfault tolerant power converterfuel cellpower supplieElectric power systemMathematical modelpower convertorElectronic engineeringcontrolled fault-tolerant power converterPower-flow studyCircuit faulthybrid power systemdistributed generationFault tolerant systembusiness.industryFault toleranceReliability engineeringPower ratingBase load power plantPower qualityModeling and Simulationpower conditioning equipmentElectric powerVectorbusinessfault tolerance;power convertors;power supply quality;controlled fault-tolerant power converters;distributed generation;fault tolerant power converters;power conditioning equipment;power quality enhancement;Circuit faults;Fault tolerance;Fault tolerant systems;Mathematical model;Power quality;Topology;Vectors;fuel cells;hybrid power systems;power supplies;power system control
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