Search results for "tolerance"

Effect of Innovative Food Processing Technologies on the Physicochemical and Nutritional Properties and Quality of Non-Dairy Plant-Based Beverages

2020

Increase in allergenicity towards cow’s milk, lactose intolerance, the prevalence of hypercholesterolemia, and flexitarian choice of food consumption have increased the market for cow’s milk alternatives. Non-dairy plant-based beverages are useful alternatives because of the presence of bioactive components with health-promoting properties, which attract health-conscious consumers. However, the reduced nutritional value and sensory acceptability of the plant-based beverages (such as flavor, taste, and solubility) compared to cow’s milk pose a big threat to its place in the market. Thermal treatments are commonly used to ensure the quality of plant-based beverages during storage. However, th…

Psychodynamic Motivation and Training program (PMT) for the secondary prevention in patients with stable coronary heart disease: study protocol for a…

2013

Background Nonpharmacological secondary prevention of coronary heart disease is considered a safe and effective measure to substantially reduce mortality. Despite the effectiveness of lifestyle changes, the compliance rate of patients is very low mainly due to psychosocial barriers. Psychotherapeutic approaches that address how persons think about themselves and their behaviors appear to have a significant potential for improving health behavior. Methods/design Against this background, our study aims to examine the feasibility and effects of a Psychodynamic Motivation and Training program (PMT) as compared to one session of advice in exercise training (EX) and treatment as usual (TAU). For …

Nitrate tolerance as a model of vascular dysfunction: Roles for mitochondrial aldehyde dehydrogenase and mitochondrial oxidative stress

2008

Organic nitrates are a group of very effective anti-ischemic drugs. They are used for the treatment of patients with stable angina, acute myocardial infarction and chronic congestive heart failure. A major therapeutic limitation inherent to organic nitrates is the development of tolerance, which occurs during chronic treatment with these agents. The mechanisms underlying nitrate tolerance remain incompletely defined and are likely multifactorial. One mechanism seems to be a diminished bioconversion of nitroglycerin, another seems to be the induction of vascular oxidative stress, and a third may include neurohumoral adaptations. Recent studies have revealed that mitochondrial reactive oxygen…

Chronotropic Incompetence Predicts Distance Walked in Six-Minute Walk Test in Heart Failure With Preserved Ejection Fraction

2020

Evaluation of in-farm versus weather station data for use as heat stress indicator in dairy sheep

2005

AbstractHeat stress is a limiting factor in dairy production in hot climates impairing growth, milk production and reproduction. The most widely investigated climatic factors related with heat stress are: air temperature and relative humidity. Previously dairy sheep studies of heat tolerance depended on measurements of physiological functions on individual animals such as rectal temperatures, respiration rates or volumes of air inhaled; unfortunately, such measurements are costly and not feasible on a large scale. This study aims to evaluate in-farm (IF) versus weather station (WS) data to be used as heat stress indicator in dairy sheep. Data were collected in three farms in November 2002 t…

Dysfunctional beliefs about health and illness: a family study

2019

Los modelos cognitivos sobre la hipocondría postulan que las experiencias tempranas con la enfermedad promueven el desarrollo de creencias disfuncionales sobre la enfermedad. Estas creencias pueden permanecer latentes y activarse ante un incidente crítico. Los estudios publicados aportan datos que avalan de mane- ra indirecta estos planteamientos. Teniendo en cuenta que en el núcleo familiar primario se comparten experiencias sobre la enfer- medad, examinamos la relación entre las creencias disfuncionales que los progenitores y sus descendientes mantienen sobre la en- fermedad y los pensamientos, tales como la intolerancia a la incer- tidumbre y la sobreestimación de la amenaza, y las relac…

Suppression of CD8+ T cell recognition in the immediate-early phase of human cytomegalovirus infection.

2012

Human cytomegalovirus (HCMV) interferes with MHC class I-restricted antigen presentation and thereby reduces recognition by CD8+ T-cells. This interference is mediated primarily by endoplasmic reticulum-resident glycoproteins that are encoded in the US2–11 region of the viral genome. Such a suppression of recognition would be of particular importance immediately after infection, because several immunodominant viral antigens are already present in the cell in this phase. However, which of the evasion proteins gpUS2–11 interfere(s) with antigen presentation to CD8+ T-cells at this time of infection is not known. Here we address this question, using recombinant viruses (RV) that express only o…

Improvement of FAO-56 Model to Estimate Transpiration Fluxes of Drought Tolerant Crops under Soil Water Deficit: Application for Olive Groves

2014

[EN] Agro-hydrological models are considered an economic and simple tool for quantifying crop water requirements. In the last two decades, agro-hydrological physically based models have been developed to simulate mass and energy exchange processes in the soil-plant-atmosphere system. Although very reliable, because of the high number of required variables, simplified models have been proposed to quantify crop water consumes. The main aim of this paper is to propose an amendment of the Food and Agricultural Organization (FAO) of the United Nations FAO-56 spreadsheet program to introduce a more realistic shape of the stress function, valid for mature olive orchards (Olea europaea L.). The mod…

Establishing a soil loss threshold for limiting rilling

2015

In this paper a frequency analysis of event soil loss measurements collected in the period 1999–2012 at the microplots and plots of the Sparacia Experimental Area in Sicily, southern Italy, was developed. The analysis was carried out using the annual maximum soil loss measurements normalized by the mean soil loss measured at a given temporal and spatial scale. The empirical frequency distribution of the normalized variable was well fitted by two Gumbel’s theoretical probability distributions discriminated by a value of the normalized variable equal to 2. This last value discriminates between the relatively low and frequent values of the normalized variable and the high and rare ones. The an…

The Role of Interleukin 10 in the Regulation of Allergic Immune Responses

2001

Several clinical studies and animal models have shown that Th2 lymphocytes play a key role in the pathophysiology of IgE-mediated allergic immune responses like allergic rhinitis and asthma or venom anaphylaxis. Classical specific immunotherapy (SIT) that has been proven to be clinically effective can serve as a role model for immunological changes that are associated with amelioration of allergic diseases. During SIT, the Th2-dominated immune response is modified towards a Th1 response leading to a decline in allergen-specific IgE and an increase in allergen-specific IgG production. Most importantly, however, production of the immunosuppressive/-regulatory cytokine interleukin 10 (IL-10) i…