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showing 10 items of 3159 documents

Resective surgical approach shows a high performance in the management of advanced cases of bisphosphonate-related osteonecrosis of the jaws: a retro…

2012

Abstract PURPOSE: The aim of this study was to evaluate the results of the surgical treatment of bisphosphonate-related osteonecrosis of the jaw (BRONJ) in a large cohort. MATERIALS AND METHODS: A retrospective cohort multicenter study was designed. Patients were enrolled if they were diagnosed with BRONJ and received operative treatment. Data on demographic, health status, perioperative, and surgical factors were collected retrospectively. The primary outcome variable was a change in BRONJ staging (improvement, worsening, or no change). Interventions were grouped by local debridement and resective surgery. Data were collected for other variables as cofactors. Univariate analysis and logist…

AdultMalemedicine.medical_specialtyMultivariate analysismedicine.medical_treatmentLogistic regressionSettore MED/28 - Malattie OdontostomatologicheHumansMedicinebisphosphonate-related osteonecrosis of the jawsAgedRetrospective StudiesAnalysis of VarianceUnivariate analysisChi-Square Distributionbusiness.industryRetrospective cohort studyPerioperativeMiddle AgedBisphosphonatemedicine.diseaseOsteotomySurgeryTreatment OutcomeDebridementItalyOtorhinolaryngologySurgical Procedures OperativeTooth ExtractionRegression AnalysisBisphosphonate-Associated Osteonecrosis of the JawFemaleSurgeryOral SurgerybusinessOsteonecrosis of the jawChi-squared distribution
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Maxillary bone necrosis following the use of formaldehyde containing paste: management and case series

2007

Paraformaldehyde is used both as a disinfectant and to devitalise inflamed pulps when local anaesthesia is ineffective. Despite the clinical benefits, paraformaldehyde is not confined to the pulp, but penetrates the dentine and is gradually released as formaldehyde. This case series describes the effects on periodontal and bone tissues of paraformaldehyde used as a devitalising or disinfectant agent.

AdultMalemedicine.medical_specialtyNecrosisPolymersDisinfectantGingivaFormaldehydeDentistryDental Pulp Devitalizationchemistry.chemical_compoundstomatognathic systemSettore MED/28 - Malattie OdontostomatologicheFormaldehydemedicineHumansParaformaldehydeGeneral DentistryRoot Canal Irrigantsbusiness.industryMouth MucosaOsteonecrosisMiddle AgedMaxillary DiseasesSurgerystomatognathic diseaseschemistryAnti-Infective Agents LocalPulp (tooth)FemaleMaxillary bone necrosis paraformaldehydemedicine.symptombusinessBritish Dental Journal
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Vitamin D deficiency in patients evaluated for obstructive sleep apnea: is it associated with disease severity?

2019

Purpose: The aim of the present study was to assess vitamin D levels in a large cohort of OSA patients and to investigate possible correlations with clinical and polysomnographic parameters. Methods: In this cross-sectional study, 685 consecutive patients underwent type 1 polysomnography (PSG) for OSA diagnosis. They were grouped according to apnea–hypopnea index (AHI) as mild, moderate, and severe. Patients with AHI < 5 served as controls. Demographic, PSG data, and serum levels of vitamin D were measured and compared between groups. Results: OSA was diagnosed in 617 of the patients (90%). Of those, 94 (15%) had mild OSA, 150 (24%) moderate OSA, and 373 (61%) severe OSA. The risk of vit…

AdultMalemedicine.medical_specialtyNeurologyVitamin D deficiency.PolysomnographyPolysomnographySettore MED/10 - Malattie Dell'Apparato RespiratorioGastroenterologyvitamin D deficiencyCohort Studies03 medical and health sciences0302 clinical medicinestomatognathic systemInternal medicinemedicineVitamin D and neurologyHumansVitamin DSleep Apnea Obstructivemedicine.diagnostic_testbusiness.industryPatient AcuityMiddle Agedmedicine.diseaseVitamin D DeficiencyObesityObstructive sleep apneanervous system diseasesrespiratory tract diseasesObstructive sleep apneaCross-Sectional Studies030228 respiratory systemOtorhinolaryngologyOtorhinolaryngologyCohortFemaleNeurology (clinical)business030217 neurology & neurosurgerySleepbreathing = SchlafAtmung
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Vascular mapping of the face: B-mode and doppler ultrasonography study.

2015

Background To analyze the face vascularization pattern using B-mode and Doppler ultrasonography, and also propose an arterial vessel mapping. Material and Methods The investigation was performed on 20 ultrasonography exams of facial vessels through linear and endocavitary transducers. We analyzed and determined the average values for diameters, peak systolic velocity and resistive index of the following arteries: external carotid, lingual, deep lingual, sublingual, facial, submental, inferior labial, superior labial, angular, maxillary inferior alveolar, mental, buccal, greater palatine, infraorbital, superficial temporal, transverse facial and frontal. Results Data was obtained allowing th…

AdultMalemedicine.medical_specialtyOdontología030230 surgery03 medical and health sciencessymbols.namesakeYoung Adult0302 clinical medicineText miningmedicineHumansGeneral DentistryOral Medicine and Pathologybusiness.industryResearchUltrasonography Doppler030206 dentistryMiddle Aged:CIENCIAS MÉDICAS [UNESCO]Ciencias de la saludArterial vesselUltrasonography dopplerstomatognathic diseasesOtorhinolaryngologyFace (geometry)FaceUNESCO::CIENCIAS MÉDICAScardiovascular systemsymbolsSurgeryFemaleRadiologyUltrasonographybusinessDoppler effectMedicina oral, patologia oral y cirugia bucal
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Treatment of chronic mandibular dislocations by eminectomy: follow-up of 10 cases and literature review.

2008

Introduction: Temporomandibular joint (TMJ) dislocation is defined as an excessive forward movement of the condyle beyond the articular eminence, with complete separation of the articular surfaces and fixation in that position. Objectives: To report ten cases treated by eminectomy for chronic mandibular dislocations, to evaluate the results of these surgeries and make a critical review of the literature. Methods: The sample was obtained from the records of the Department of Oral and Maxillofacial Surgery, University of Pernambuco and comprises cases submitted to chronic mandibular dislocation treatment by eminectomy between 2002 and 2007. Pre- and postoperative assessment included a thoroug…

AdultMalemedicine.medical_specialtyOral Surgical ProceduresJoint DislocationsPhysical examinationOral Surgical ProceduresCondyleYoung Adultstomatognathic systemRecurrencemedicineParalysisHumansJoint dislocationGeneral Dentistrymedicine.diagnostic_testbusiness.industryMiddle AgedTemporomandibular Joint Disordersmedicine.disease:CIENCIAS MÉDICAS [UNESCO]Facial nerveSurgeryTemporomandibular jointstomatognathic diseasesmedicine.anatomical_structureOtorhinolaryngologyUNESCO::CIENCIAS MÉDICASOral and maxillofacial surgerySurgeryFemalemedicine.symptombusinessMedicina oral, patologia oral y cirugia bucal
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Prevalence of the different Axis I clinical subtypes in a sample of patients with orofacial pain and temporomandibular disorders in the Andalusian He…

2015

Background: The main objective of this paper is to analyze the prevalence of each of the different clinical subtypes of temporomandibular disorders (TMD) in a sample of patients with this pathology. In addition, a second objective was to analyze their distribution according to gender. Material and Methods: To this end, the results of 1603 patients who went to the Unit of Temporomandibular Disorders in the Córdoba Healthcare District because they suffered from this pathology were analyzed. In order to diagnose them, the Research Diagnostic Criteria for Temporomandibular Disorders (RDC/TMD) were applied, analyzing the different Axis I subtypes (myopathy, discopathy and arthropathy) and obtain…

AdultMalemedicine.medical_specialtyOrofacial paingenetic structuresAdolescentSample (statistics)Odontología03 medical and health sciencesHealth servicesYoung Adult0302 clinical medicineFacial PainInternal medicinePrevalenceMedicineHumansFacial painYoung adultSex DistributionGeneral DentistryAgedAged 80 and overOral Medicine and Pathologybusiness.industryResearch030206 dentistryHealth ServicesMiddle AgedTemporomandibular Joint Disorders:CIENCIAS MÉDICAS [UNESCO]Ciencias de la saludstomatognathic diseasesOtorhinolaryngologySpainUNESCO::CIENCIAS MÉDICASPhysical therapySurgeryFemalemedicine.symptomHealthcare servicebusiness030217 neurology & neurosurgery
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Evaluation of the diagnostic value of a Modified Liquid-Based Cytology using OralCDx Brush in early detection of oral potentially malignant lesions a…

2009

Objectives: To determine diagnostic value of modified Liquid Based Brush Biopsy technique. Study design: 26 oral premalignant and malignant lesions in 25 patients (12 females; 54.23±19.77 years and 13 males; 53.77±15.43 years) underwent Modified (Liquid Based) Brush Biopsy and scalpel biopsy simultaneously from the same area. Results: There were 16 positive and 10 negative brush biopsy results, with no inadequate readings. Histological findings were compatible with oral leukoplakia(n=5)with dysplasia, Oral lichen planus and lichenoid reaction(n=7) (with or without dysplasia)oral squamous cell carcinoma(n=11),verrucous carcinoma(n=1) and granular cell tumors( n=2). Sensitivity, specificity, …

AdultMalemedicine.medical_specialtyPathologyBiopsyEarly detectionGastroenterologylaw.inventionYoung AdultlawInternal medicineBiopsymedicineHumansGeneral DentistryEarly Detection of CancerAgedmedicine.diagnostic_testVerrucous carcinomabusiness.industryBrushCancerMiddle Agedmedicine.disease:CIENCIAS MÉDICAS [UNESCO]stomatognathic diseasesOtorhinolaryngologyDysplasiaLiquid-based cytologyUNESCO::CIENCIAS MÉDICASSurgeryOral lichen planusFemaleMouth Neoplasmsbusiness
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Management of fibro-osseous lesions of the craniofacial area: presentation of 19 cases and review of the literature

2013

Introduction: Fibro-osseous lesions constitute a rare benign type of pathology with a non-odontogenic lineage that affect the craniofacial area. According to Waldrom’s classification, these lesions are divided into: fibrous dysplasia (FD), cemento-ossifying fibroma (COF) and desmoplastic fibroma (DF). Material and Methods: A retrospective study was performed on patients diagnosed with fibro-osseous lesions of the craniofacial area at the Hospital Universitario La Fe, Valencia, during 1987-2009. A total of 19 cases were collected: 15 cases compatible with an FD diagnosis, 3 cases with a COF diagnosis and 1 case with a DF diagnosis. Results: In the differential diagnosis, entities having simi…

AdultMalemedicine.medical_specialtyPathologyBone NeoplasmsOdontologíaFibrous Dysplasia PolyostoticAsymptomaticFacial BonesLesionYoung AdultDesmoplastic fibromamedicineHumansCraniofacialChildGeneral DentistryAgedRetrospective Studiesbusiness.industryFibrous dysplasiaSkullReview-ArticleFibroma DesmoplasticRetrospective cohort studyFibrous Dysplasia of BoneMiddle Agedmedicine.disease:CIENCIAS MÉDICAS [UNESCO]Ciencias de la saludstomatognathic diseasesOtorhinolaryngologyChild PreschoolFibroma OssifyingUNESCO::CIENCIAS MÉDICASFemaleSurgeryRadiologyOral Surgerymedicine.symptomFibromaDifferential diagnosisbusiness
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CYP2C8 gene polymorphism and bisphosphonate-related osteonecrosis of the jaw in patients with multiple myeloma

2011

Osteonecrosis of the jaw is an uncommon but potentially serious complication of bisphosphonate therapy in multiple myeloma. Previous studies showed that the presence of one or two minor alleles of the cytochrome P450, subfamily 2C polypeptide 8 gene (CYP2C8) polymorphism rs1934951 was an independent prognostic marker associated with development of osteonecrosis of the jaw in multiple myeloma patients treated with bisphosphonates. The aim of this study was to validate the frequency of SNP rs193451 in 79 patients with multiple myeloma. In 9 (22%) patients developing osteonecrosis of the jaw, a heterozygous genotype was found, in contrast with those who did not develop osteonecrosis of the jaw…

AdultMalemedicine.medical_specialtyPathologyCYP2C8Genotypemedicine.medical_treatmentONJGastroenterologyPolymorphism Single NucleotideCytochrome P-450 CYP2C8stomatognathic systemInternal medicineGenotypemedicineSNPHumansAllelebisphosphonatesMultiple myelomaAllelesAgedAged 80 and overBisphosphonate-associated osteonecrosis of the jawbusiness.industryHematologyBisphosphonateMiddle Agedmedicine.diseasemultiple myelomastomatognathic diseasesBisphosphonate-Associated Osteonecrosis of the JawFemaleBrief ReportsAryl Hydrocarbon HydroxylasesOsteonecrosis of the jawComplicationbusinessMultiple Myeloma
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Subcortical ischaemic changes in young hypertensive patients: frequency, effect on cognitive performance and relationship with markers of endothelial…

2007

Information on subcortical ischaemic changes (SIC) in young hypertensive patients is scarce. We evaluated the frequency of SIC at magnetic resonance imaging (MRI), the possible effect on cognition of these patients, and the role of plasma markers known as indicators of endothelial and haemostatic activation. Inclusion criteria were age <or=54 years, hypertension for at least 2 years and absence of cerebrovascular disease or other conditions possibly related to SIC. Patients with SIC at MRI and two control groups (matched for age, sex and education) of hypertensive patients without SIC and non-hypertensive healthy subjects underwent an extensive neuropsychological examination and evaluation …

AdultMalemedicine.medical_specialtyPathologyEndotheliumNeuropsychological TestsBrain IschemiaCognitionstomatognathic systemVon Willebrand factorInternal medicinemedicineHumansAge FactorEffects of sleep deprivation on cognitive performanceEndothelial dysfunctionHemostasisbiologymedicine.diagnostic_testbusiness.industryAge FactorsNeuropsychologyBrainMagnetic resonance imagingBiomarkerHemostasiMiddle Agedmedicine.diseaseMagnetic Resonance ImagingBlood pressuremedicine.anatomical_structureNeurologyHemostasisHypertensionCardiologybiology.proteinFemaleEndothelium VascularNeurology (clinical)businessBiomarkersHumanEuropean Journal of Neurology
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