Search results for "tradition"

The hallmark of anonymity. Questions of authorship in the Hippocratic Corpus, specifically regarding the so-called 'Author C'

2020

Since Émile Littrés’ time a particular attention has been devoted to a group of Hippocratic treatises (On Generation/On the Nature of the Child + Book IV of Diseases) showing a significant range of affinities and common elements in language, style, tenor and thought. Studies by Hermann Grensemann (in the 1980s) contributed to further philological analysis of the peculiar traits of the so-called Hippocratic ‘author C’, widening the textual basis to be involved in the investigation (including gynaecological treatises like On Diseases of Women 1-2 as well as parts of Infertile Women). Recently new light has also been shed by Elizabeth Craik (editing 2009 the treatise On Glands) on the historic…

Rediscovering tradition through representation: the vaulted house of the Amalfi Coast

2022

The Amalfi Coast represents one of the most fascinating examples of Mediterranean landscape with a unique cultural and natural setting, resulting from its dramatic topography and the evolution of its community. The universal value of the coast, the evolutionary process of human adaptation to its production and exchange spaces, as well as its residential settlements, is very important to preserve. In this regard, the research is focused on the interpretation of these places, and in particular on the typical medieval houses to find the main features through the representation of ancient and new designers. The observation through the drawing allows rediscovering the essential elements that dis…

Phytochemical profile and insecticidal activity of Drimia pancration (Asparagaceae) against adults of Stegobium paniceum (Anobiidae)

2020

Chemical and spectroscopic investigation of the bulbs of Drimia pancration resulted in the isolation of one known flavonol (1), never isolated from this plant species, and of three previously described steroidal saponins (2–4), but whose configuration at their stereogenic centres was not clearly determined. By mean of 1H NMR, 13C NMR, nuclear overhauser effects (NOE) and two-dimensional NMR spectra the full stereochemical structures of compounds 2–4 were proved and all the 1H and 13C signals were assigned. Furthermore, the methanol and butanol extracts of D. pancration were tested against adults of Stegobium paniceum beetles. Despite the non-significant results regarding the repellent activ…

Novel yeast extract is superior to colloidal oatmeal in providing rapid itch relief

2020

Background Approximately, 13.5% of the population suffers from chronic itch. Many cosmetic and pharmaceutical treatments for itch are available; however, cosmetic treatments are not reliably effective and most pharmaceutical formulations carry the risk of adverse events with chronic use. Aims Previously, we have reported a novel extraction process of Saccharomyces cerevisiae, that is, Baker's yeast. The extract obtained from the novel process demonstrates superior anti-itch properties compared to other yeast extracts. In our previous study, we demonstrated that, after 30 minutes, the extract significantly reduced itch when compared to a placebo lotion (P = .002). Methods In the present stud…

In vitro activities of antimicrobial agents against Candida species

1999

Objective. Antimicrobial mouthrinses may represent a valid alternative to topical antifungal agents. However, the action of antimicrobials could be affected by the different ingredients incorporated into mouthrinse products. The purpose of the present study was to investigate the in vitro antifungal and fungicidal activities of antimicrobials alone. Study Design. A broth macrodilution method was used to determine the minimum inhibitory concentration of 4 antimicrobial agents against Candida species. Minimum fungicidal concentration was also determined. Results. All antimicrobials showed antifungal activity against all tested organisms, but cetylpyridinium chloride received significantly low…

Cytotoxicity of aloe-emodin towards several drug sensitive cells and their resistant counterparts

2017

Natural polyphenols in cancer therapy.

2011

Natural polyphenols are secondary metabolites of plants involved in defense against different types of stress. Extracts containing these compounds have been used for thousands of years in traditional eastern medicine. Polyphenols act on multiple targets in pathways and mechanisms related to carcinogenesis, tumor cell proliferation and death, inflammation, metastatic spread, angiogenesis, or drug and radiation resistance. Nevertheless, reported effects claimed for polyphenols are controversial, since correlations between in vitro effects and in vivo evidence are poorly established. The main discrepancy between health claims versus clinical observations is the frequent use of nonphysiological…

Adverse drug reactions in some African herbal medicine: literature review and stakeholders’ interview

2014

International audience; Background: In view of the large consumption of herbal medicine in Africa countries, it is likely that many adverse drugs reactions go unrecorded with either patients failing to present to health services, or no pharmacovigilance analysis being made, or the analysis not being reported centrally. This problem is of interest especially for those who are working in the general area of adverse drug reactions or stakeholders in the domain of herbal medicine for considering safety issues. Methods: We are particularly interested in the way that the use of very wellknown and highly valued plants is linked to the observation of adverse drug reactions in African countries. We …

Herbal Medicines: Boon or Bane for the Human Liver?

2016

Since ages, medicine is the most consistent companion of man. While in primeval time, disease was cured through natural preparations, onset of technology has made today’s formulations synthetic or nature derived. Across the ages, the plausibility of the “savior-turned-slayer” functionality of these drugs remained constant. With the increment in documentation, it becomes evident that many of the commonly used drugs are associated with toxicities. Thus, any drug, irrespective of its origin, needs to be thoroughly assessed. Rampant use of herbal drugs has often been a threat to human health owing to the scarcity in quality assessment. What needs to be understood is that everything natural is n…

Herbal hepatotoxicity: a hidden epidemic

2011

Complementary and alternative therapies, including herbal products, have become increasingly popular in the general population and among patients and physicians. Regulations and pharmacovigilance regarding herbal drugs are still incomplete and need to be improved. In fact, herbals are commonly marketed on the Internet, and in many countries they are sold as food supplements, which are beyond the control of drug regulatory agencies. In Europe and the U.S., reports of hepatotoxicity from these products, including those advertised for liver diseases, are accumulating. Many herbal drugs are also commonly used in children, and in women during pregnancy and lactation, because they are believed to…