Search results for "trap"
showing 10 items of 2144 documents
Solid and Semisolid Innovative Formulations Containing Miconazole-Loaded Solid Lipid Microparticles to Promote Drug Entrapment into the Buccal Mucosa
2021
The currently available antifungal therapy for oral candidiasis (OC) has various limita- tions restricting its clinical use, such as short retention time, suboptimal drug concentration and low patients compliance. These issues could be overcome using micro or nanotechnology. In par- ticular, solid lipid microparticles (SLMs) resulted as a particularly promising penetration enhancer carrier for lipophilic drugs, such as the antifungal miconazole (MCZ). Based on these considera- tions, cetyl decanoate (here synthesized without the use of metal catalysis) was employed together with 1-hexadecanol to prepare MCZ-loaded SLMs. These resulted in a powder composed of 45–300 µm diameter solid spheric…
Interactions and Monitoring of Antipsychotic Drugs
2012
As a consequence of individualized antipsychotic pharmacotherapy, many patients need more than a single drug, since they do not respond sufficiently to monotherapy. Other patients suffer from comorbid diseases and therefore require additional drugs from other pharmacological classes. Drug combinations, however, can give rise to pharmacokinetic and/or pharmacodynamic drug–drug interactions. Evaluation of pharmacokinetic interactions with antipsychotic drugs must consider substrate, inhibitor, and inducer properties for the cytochrome P450 (CYP) isoenzymes of all combined drugs. For consideration of pharmacodynamic interactions, special attention must be given to effects on dopamine D2, hista…
The B 1Pi state of NaCs: high resolution laser induced fluorescence spectroscopy and potential construction.
2007
The lowest (1)Pi state of the NaCs molecule, the B(1)(1)Pi state, was studied using a dye laser for inducing fluorescence that was resolved by a high resolution Fourier-transform spectrometer. The presence of argon buffer gas yielded rich rotational relaxation spectra allowing to enlarge the data set for the B(1)(1)Pi state, to obtain Lambda-splittings and to reveal numerous local perturbations. 543 weakly perturbed energy levels for rotational quantum numbers from J(')=5 to 168 and vibrational quantum numbers from v(')=0 to 25, which cover about 87% of the potential well depth, were used for a direct pointwise fit of the potential energy curve applying the inverted perturbation approach me…
La cheratoplastica lamellare profonda: indicazioni, tecnica e risultati.
2009
Exploring the mass surface near the rare-earth abundance peak via precision mass measurements at JYFLTRAP
2019
The JYFLTRAP double Penning trap at the Ion Guide Isotope Separator On-Line (IGISOL) facility has been used to measure the atomic masses of 13 neutron-rich rare-earth isotopes. Eight of the nuclides, $^{161}$Pm, $^{163}$Sm, $^{164,165}$Eu, $^{167}$Gd, and $^{165,167,168}$Tb, were measured for the first time. The systematics of the mass surface has been studied via one- and two-neutron separation energies as well as neutron pairing-gap and shell-gap energies. The proton-neutron pairing strength has also been investigated. The impact of the new mass values on the astrophysical rapid neutron capture process has been studied. The calculated abundance distribution results in a better agreement w…
Dall’immagine all’indagine: la restituzione prospettica da foto d’epoca per la ricostruzione della chiesa di San Michele a Trapani
2022
La Chiesa di San Michele a Trapani, piccolo edificio religioso di impianto parzialmente rinascimentale, è stata demolita alla fine degli anni’50 del Novecento; di essa rimangono poche informazioni storiche e grafiche; la memoria della chiesa è oggi affidata a poche immagini fotografiche che raffigurano scroci dell’interno e di un fronte esterno. La tecnica della restituzione prospettica di foto d’epoca per la ricostruzione virtuale di edifici scomparsi è stata con successo applicata in recenti ricerche. La restituzione prospettica con metodi digitali si stacca dal piano dell’immagine per giungere, a seguito della determinazione degli schemi prospettici, alla ricostruzione tridimensionale de…
Un “teatro sacro” di Andrea Pozzo nella chiesa dell'Immacolatella a Trapani di Giovanni Amico (dal 1732): storia, fonti, rilievo
2022
Il contributo, articolato tra storia e rappresentazione, ha l’obiettivo di analizzare la genesi progettuale e le fonti utilizzate dall’architetto Giovanni Amico per l’ammodernamento della tribuna della chiesa dell’Immacolatella a Trapani (dal 1732). L’opera è oggi priva di studi e di rilievi ma per le sue caratteristiche compositive, che sfruttano il tema della manipolazione dello spazio e della luce con finalità scenografiche, appartiene a una serie prodotta in Sicilia da Amico che è possibile collegare al mondo progettuale romano e soprattutto di Andrea Pozzo in relazione ai “teatri sacri” prodotti per i Gesuiti e conosciuti tramite le incisioni del suo celebre trattato, ma anche attraver…
A similar to 32-70 K FORMATION TEMPERATURE RANGE FOR THE ICE GRAINS AGGLOMERATED BY COMET 67 P/CHURYUMOV-GERASIMENKO
2015
Grand Canonical Monte Carlo simulations are used to reproduce the N$_2$/CO ratio ranging between 1.7 $\times$ 10$^{-3}$ and 1.6 $\times$ 10$^{-2}$ observed {\it in situ} in the Jupiter family comet 67P/Churyumov-Gerasimenko by the ROSINA mass spectrometer aboard the Rosetta spacecraft, assuming that this body has been agglomerated from clathrates in the protosolar nebula. Simulations are done using an elaborated interatomic potentials for investigating the temperature dependence of the trapping within a multiple guest clathrate formed from a gas mixture of CO and N$_2$ in proportions corresponding to those expected for the protosolar nebula. By assuming that 67P/Churyumov-Gerasimenko agglom…
CONSTRUCTING, BOOTSTRAPPING, AND COMPARING MORPHOMETRIC AND PHYLOGENETIC TREES: A CASE STUDY OF NEW WORLD MONKEYS (PLATYRRHINI, PRIMATES)
2005
Morphometric data sets are often phenetically analyzed by using various kinds of spatial, metric, or nonmetric multivariate analyses. Such methods produce results that are difficult to compare directly with molecular or morphological phylogenetic hypotheses, which are usually expressed by using nonspatial tree representations. Therefore, it is useful in a comparative approach to analyze, and above all to visualize, morphometric pairwise relationships as tree structures. For this purpose, several additive or ultrametric methods exist, which often return different topologies for the same data set. Objective criteria are thus needed to identify the tree-building algorithm (or algorithm family)…
New paradigm of ICT productivity – Increasing role of un-captured GDP and growing anger of consumers
2015
Abstract The dramatic advancement of the Internet has led all nations to an information communication technology (ICT) driven development trajectory. This trajectory has resulted in bi-polarization between ICT growing economies and ICT advanced economies. While the former enjoys a virtuous cycle between ICT advancement and productivity increase, the later has fallen into a trap of a vicious cycle between ICT advancement and productivity decrease. This paper identifies that this trap can be attributed to the two-faced nature of ICT in which advancement of ICT contributes to price increases due to functionality development while dramatic advancement of the Internet has resulted in price decre…