Search results for "troponins"

showing 5 items of 5 documents

Head-to-head comparison of plasma cTnI concentration values measured with three high-sensitivity methods in a large Italian population of healthy vol…

2019

Abstract Background The study aim is to compare cTnI values measured with three high-sensitivity (hs) methods in apparently healthy volunteers and patients admitted to emergency department (ED) with acute coronary syndrome enrolled in a large multicentre study. Methods Heparinized plasma samples were collected from 1511 apparently healthy subjects from 8 Italian clinical institutions (mean age: 51.5 years, SD: 14.1 years, range: 18–65 years, F/M ratio:0.95). All volunteers denied chronic or acute diseases and had normal values of routine laboratory tests. Moreover, 1322 heparinized plasma sample were also collected by 9 Italian clinical institutions from patients admitted to ED with clinica…

Male0301 basic medicineprincipal component analysisvery elderlyClinical BiochemistryheparinizationBiochemistryPatient Admission0302 clinical medicineReference ValuesLimit of Detectionblood analysisTroponin IHealthy volunteers80 and overMyocardial infarctionAcute coronary syndrome; Cardiac troponins; High-sensitivity methods; Myocardial infarction; Reference population values; Acute Coronary Syndrome; Adolescent; Adult; Aged; Aged 80 and over; Blood Chemical Analysis; Female; Humans; Italy; Male; Middle Aged; Myocardium; Patient Admission; Reference Values; Troponin I; Young Adult; Emergency Service Hospital; Healthy Volunteers; Limit of DetectionReference population valuescomparative studyHigh-sensitivity methodsAged 80 and overemergency wardEmergency Servicehospital emergency servicetroponin I acute coronary syndromeSettore BIO/12clinical trialGeneral Medicinecardiac troponin 1 CLIAMiddle AgedHealthy Volunteerspriority journalItaly030220 oncology & carcinogenesisCardiac troponinFemaleAcute coronary syndromeEmergency Service HospitalAdultmedicine.medical_specialtyAcute coronary syndromecardiac muscleAdolescentHead to headheart infarctionArticleYoung AdultHospital03 medical and health sciencesbloodInternal medicinemedicinesexHumanscontrolled studyADVIA Centaurdiagnostic test accuracy studyhumannormal humanproceduresAgedbusiness.industryMyocardiumTroponin IBiochemistry (medical)reference valueEmergency departmentmedicine.diseasemajor clinical studyhospital admissionyoung adult Acute Coronary SyndromeHigh-sensitivity methodMyocardial infarctionmulticenter study030104 developmental biologySettore BIO/12 - Biochimica Clinica E Biologia Molecolare Clinicaageprotein blood levelReference valuesCardiac troponinsbusinessmetabolismBlood Chemical Analysis
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Cardiac troponin I and T: Exploring popularity with Google Trends

2020

The implementation of high-sensitivity cardiac troponin T (hs-cTnT) assays and a cutoff based on the 99th cTnT percentile in the evaluation of patients with suspected acute coronary syndrome has not been uniform due to uncertain effects on health benefits and utilization of limited resources.Clinical and laboratory data from patients with chest pain or dyspnea at the emergency de¬partment (ED) were evaluated before (n = 20516) and after (n = 18485) the lowering of the hs-cTnT cutoff point from 40 ng/L to the 99th hs-cTnT percentile of 14 ng/L in February 2012. Myocardial infarction (MI) was diagnosed at the discretion of the attending clinicians responsible for the patient.Following lowerin…

Malemedicine.medical_specialtyCardiac troponinMEDLINEGoogle TrendsClinical CardiologyElectrocardiographyPatient AdmissionTroponin TPredictive Value of TestsInternal medicinemedicineHumansHospital MortalityAcute Coronary SyndromeHospital CostsIntensive care medicineAgedRetrospective StudiesAged 80 and overCardiac troponins popularity Google Trendspopularitybusiness.industryTroponin IGeneral MedicineMiddle AgedPopularityHospitalsHospitalizationSurvival RateCardiologyFemaleCardiac troponinsCardiology and Cardiovascular MedicinebusinessEmergency Service HospitalBiomarkersFollow-Up Studies
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Prognostic value of troponin I in atrial fibrillation

2021

To evaluate whether circulating cardiac troponin I (cTnI) levels are associated with worst outcomes in patients with atrial fibrillation (AF).Consecutive patients visiting the emergency room (ER) with a new episode of a previously diagnosed AF or a new diagnosis of AF during ER admission between January 1st, 2010 and December 31st, 2015, were enrolled in the study (n = 2617). After applying exclusion criteria and eliminating repeated episodes, 2013 patients were finally included. Of these, 1080 patients with at least one cTnI measurement in the ER were selected and classified into 4 groups according to cTnI quartiles: Q1 (n = 147) cTnI10 ng/L (Group 1); Q2 (n = 254): 10-19 ng/L (Group 2); Q…

Malemedicine.medical_specialtyTime FactorsHeart failureComorbidity030204 cardiovascular system & hematologyRisk Assessment03 medical and health sciences0302 clinical medicinePredictive Value of TestsRisk FactorsInternal medicineTroponin ImedicineClinical endpointAtrial fibrillation Emergency Heart failure Mortality TroponinsTroponinsHumans030212 general & internal medicineRisk factorMortalityAdverse effectAgedRetrospective StudiesAged 80 and overbiologybusiness.industryTroponin IAtrial fibrillationMiddle AgedPrognosismedicine.diseaseTroponinAtrial fibrillationQuartileHeart failureEmergencybiology.proteinFemaleEmergency Service HospitalCardiology and Cardiovascular MedicinebusinessBiomarkers
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Hs-cTnT levels in professional soccer players throughout a season: No evidence of sustained cardiac damage

2015

a Research Institute of the Hospital 12 de Octubre (“i + 12”), Madrid, Spain b Research Institute “Dr. Vina Giner”, Molecular and Mitochondrial Medicine, Catholic University of Valencia San Vicente Martir, Valencia, Spain c School of Medicine, Catholic University of Valencia San Vicente Martir, Valencia, Spain d Human Performance Laboratory, MAPEI Sport Research Center, Italy e Department of Physical Education and Sports, University of Valencia, Valencia, Spain f Laboratory of Experimental Biochemistry & Molecular Biology, I.R.C.C.S. Istituto Ortopedico Galeazzi, Milano, Italy g Laboratory of Clinical Chemistry and Hematology, Academic Hospital of Parma, Parma, Italy

Malemedicine.medical_specialtybiologybusiness.industryPhysical ExertionFootballbiology.organism_classificationVentricular Function LeftExercise; Football; Training; TroponinsCardiovascular DiseasesPhysical Conditioning AnimalTroponinsPhysical therapymedicineTrainingAnimalsMyocytes CardiacCardiology and Cardiovascular MedicinebusinessExerciseValenciaHumanitiesInternational Journal of Cardiology
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Cardiac troponin release during and after endurance exercise: epidemiologic health implications.

2020

medicine.medical_specialtyCardiac troponinMEDLINECoronary DiseaseheartGlobal HealthEndurance trainingInternal medicinemedicineHumansHealth implicationsphysiological adaptationsbiologyexercisebusiness.industryIncidenceTroponindamage; exercise; heart; physiological adaptations; troponinsTroponinPhysiological AdaptationsEndurance Trainingbiology.proteinCardiologyMolecular MedicinetroponinsCardiology and Cardiovascular MedicinebusinessdamageBiomarkersFuture cardiology
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