Search results for "tumori"
showing 10 items of 62 documents
TERATOMA IMMATURO EXTRACRANICO: Risultati dello Studio Cooperativo AIEOP "TCG-91".
1998
I Teratomi Immatuti sono tumori costituiti da tessuto non maligno ma con potenzialità evolutiva maligna. Gli Autori presentano i dati dello Studio Cooperativo "TCG-91".
YOLK SAC DEL TESTICOLO: Raro Caso con Metastasi Gigante Retroperitoneale
1989
The authors restorate a case of primary testis tumor (Yolk Sac Tumor) and giant retroperitoneal metastasis clinically evident as a voluminous abdominal mass (23 cm) and associated virilizing syndrome. the diagnostic and therapeutic procedure performed is described.
LE NEOPLASIE CISTICHE BENIGNE DEL TESTICOLO IN ETA' PEDIATRICA: revisione della letteratura, contributo clinico personale e nuove proposte terapeutic…
1990
Gli Autori ribadiscono l'importanza dell'approccio multisciplinare alle masse del testicolo e sottolineano il corretto atteggiamento terapeutico, sulla base della revisione della letteratura e dopo valutazione dei dati di una casistica nazionale
EPATOBLASTOMI (EPB): UN SUCCESSO DELLA RIUCERCA CLINICA
1994
Dalla revisione della casistica del gruppo di Studio Italiano sui Tumori epatici del Bambino (GSTEB), risulta un miglioramento dell'Outcome di questi pazienti. Gli Autori presentano i risultati dello Studio.
Le biopsie mini invasive nei tumori ossei e delle parti molli: aspetti gestionali e considerazioni cliniche
2015
Non previsto
I TUMORI INFANTILI E DEGLI ADOLESCENTI: TREND DI INCIDENZA E STUDIO DI EVENTUALI CLUSTER. CONFRONTO TRA LE PROVINCE DI PALERMO E DI CALTANISSETTA NEL…
2017
INTRODUZIONE: Nonostante i progressi nelle strategie terapeutiche e il conseguente miglioramento della sopravvivenza, i tumori infantili rappresentano un importante problema di salute pubblica. È stato effettuato un confronto tra l’incidenza dei tumori infantili (0-14 anni) e degli adolescenti (15-19 anni) nelle province di Palermo e di Caltanissetta, nel periodo 2007-2012. MATERIALI E METODI: Sono stati analizzati 453 nuovi casi di tumore maligno e i non maligni del SNC in soggetti <20 anni, registrati dal Registro Tumori di Palermo Provincia (RTPP) e dal Registro Tumori di Ragusa e Caltanissetta (RTRC) tra il 2007 e il 2012. Variazioni delle medie annue percentuali sono state calcolate…
I tumori dei bambini e degli adolescenti nella provincia di Palermo: i dati del Registro Tumori di Palermo e provincia.
2015
Tumori infantili; Registri Tumori; Incidenza
Abnormal peripubertal development of the rat mammary gland following exposure in utero and during lactation to a mixture of genistein and the food co…
2011
The impact of early exposure to endocrine disruptor mixtures on mammary gland development is poorly known. Here, we identify the effects of a conception to weaning exposure of rats to the phytoestrogen genistein (G) and/or the antiandrogen vinclozolin (V) at 1 mg/kg-d, alone or in association. Using several approaches, we found that G- and GV-exposed rats displayed significantly greater epithelial branching and proliferation, wider terminal end buds than controls at PND35, as well as ductal hyperplasia and periductal fibrosis. Focal branching defects were present in V-exposed rats. An increased ER and AR expression was observed in G- and CV- as compared to V-exposed rats at PND35. Surprisin…
Abnormal peripubertal development of the rat mammary gland following exposure in utero and during lactation to a mixture of genistein and the food co…
2012
The impact of early exposure to endocrine disruptor mixtures on mammary gland development is poorly known. Here, we identify the effects of a conception to weaning exposure of rats to the phytoestrogen genistein (G) and/or the antiandrogen vinclozolin (V) at 1 mg/kg-d, alone or in association. Using several approaches, we found that G- and GV-exposed rats displayed significantly greater epithelial branching and proliferation, wider terminal end buds than controls at PND35, as well as ductal hyperplasia and periductal fibrosis. Focal branching defects were present in V-exposed rats. An increased ER and AR expression was observed in G- and CV- as compared to V-exposed rats at PND35. Surprisin…
Targeting lysine-specific demethylase 1 (KDM1A/LSD1) impairs colorectal cancer tumorigenesis by affecting cancer cells stemness, motility, and differ…
2023
: Among all cancers, colorectal cancer (CRC) is the 3rd most common and the 2nd leading cause of death worldwide. New therapeutic strategies are required to target cancer stem cells (CSCs), a subset of tumor cells highly resistant to present-day therapy and responsible for tumor relapse. CSCs display dynamic genetic and epigenetic alterations that allow quick adaptations to perturbations. Lysine-specific histone demethylase 1A (KDM1A also known as LSD1), a FAD-dependent H3K4me1/2 and H3K9me1/2 demethylase, was found to be upregulated in several tumors and associated with a poor prognosis due to its ability to maintain CSCs staminal features. Here, we explored the potential role of KDM1A tar…