Search results for "uci"
showing 10 items of 5317 documents
Análisis de resultados e intervención del PNAE MT- Brasil
2017
Análisis de Resultados e Intervención del PNAE MT-Brasil Análisis de Resultados e Intervenção do PNAE MT-Brasil (en portugues) La finalidad inicial de este estudio, se apoyó en la búsqueda y mejoría del Programa de Alimentación Escolar-PNAE- Mato Grosso-Brasil, a partir de una educación alimentaria y nutricional, que pudiese ofrecer contribución significativa, para la ejecución del Programa de Alimentación Escolar (PAE-MT), a través de la visualización de los problemas/limitaciones encontradas en la ejecución del programa en (2014), y esto fue posible mediante el análisis de las respuestas que los directores escolares, padres, estudiantes y técnicos en alimentación escolar (manipuladores), …
Tema 4. El marc institucional de la Unió Europea (I). Curs acadèmic 2022 - 2023.
2022
El document forma part dels materials docents presentants al Servei de Política Lingüística de la Universitat de València, convocatòria Premis Fernando Sapiña 2022 a la qüalitat lingüística en l’elaboració de materials docents en valencià. 1. Característiques del marc institucional. 2. El repartiment de competències i funcions entre les institucions. 3. Principis rectors aplicables al marc institucional. 4. El Parlament Europeu. 5. El Consell Europeu
Hyvästä elämästä ja kuolemasta
2019
El empleo público local en la España democrática: una perspectiva institucional
2013
La investigación plantea responder a una pregunta: a tenor de los indicios existentes en la Administración Local (clientelismo, corrupción) ¿por qué este nivel de gobierno no ha logrado consolidar un empleo público profesional? Con el armazón teórico del nuevo institucionalismo de las ciencias sociales, en especial su enfoque histórico y de elección racional (o analítico) se plantea como hipótesis la de que hay que indagar en los momentos formativos de este marco institucional, los años ochenta, periodo que constituyó una auténtica coyuntura crítica, en el que coincidieron diversas secuencias causales (reformas) y en donde arraigaron diversos modos de hacer que se han consolidado con el pas…
Study of the aryl hydrocarbon receptor mediated effects through in silico modeling and in vitro bioassays
2020
The aryl hydrocarbon receptor (AhR) is a cytoplasmatic sensor of diverse endogenous and exogenous substances. In a toxicological context, the former known as “dioxin receptor” has been investigated as a xenobiotic chemoreceptor and due to its roles in mediating carcinogenesis, endocrine disruption, among other immunological, hepatic, cardiovascular, and dermal toxicity mechanisms. The deep physiological implications of AhR in cellular proliferation, adhesion, division, differentiation, as well as in the reproductive, immunological and cardiovascular homeostasis have opened a new field of research in order to harness AhR’s pharmacological potential. Hence, AhR has become a therapeutic target…
miR-31-5p Is a LIPUS-Mechanosensitive MicroRNA that Targets HIF-1α Signaling and Cytoskeletal Proteins
2019
The roles of low-intensity pulsed ultrasound (LIPUS) and microRNAs (miRNAs) on hMSCs commitments have already been investigated
Method optimization to measure polybrominated diphenyl ether (PBDE) concentrations in soils of Bratislava, Slovakia.
2010
We modified an analytical method to determine polybrominated diphenyl ethers (PBDEs) in urban soils of Bratislava (Slovakia). Gel permeation chromatography (GPC) introduced as a clean-up step for soil extracts substantially reduced matrix enhancements when PBDEs were measured with gas chromatography-negative chemical ionization-mass spectrometry (GC-NCI-MS). The resulting method proved to be accurate, precise, and showed low detection limits. The sum of 15 PBDE concentrations in surface horizons of Bratislava soils ranged from 87 to 627 pg g(-1). PBDE concentrations were mostly higher in surface than deeper horizons probably because of atmospheric deposition and lack of substantial vertical…
Standardization of a bioassay for thyrotropin receptor stimulating autoantibodies.
2015
Cell-based bioassays for functional thyroid stimulating autoantibodies (TSAb) are sensitive diagnostic tools. However, there is no bioassay available that is standardized with international reference material. We aimed to promote the standardization of the test results among laboratories that perform TSAb bioassays and calibrate TSAb levels against the second international standard (IS) 08/204 from the National Institute for Biological Standards and Control (NIBSC).Serum TSAb activity was measured with a FDA-cleared bioassay that utilizes CHO cells expressing a chimeric thyrotropin receptor (TSHR) and a c-AMP response-element-dependent luciferase. The IS was applied for calibration. TSAb re…
Intermittent hypobaric hypoxia applicability in myocardial infarction prevention and recovery.
2012
Abstract Intermittent hypobaric hypoxia (IHH) has been the focus of important research in cardioprotection, and it has been associated with several mechanisms. Intermittent hypobaric hypoxia inhibits prolyl hydroxylases (PHD) activity, increasing the stabilization of hypoxia-inducible factor-1 (HIF-1) and activating crucial adaptative genes. It has been hence suggested that IHH might be a simple intervention, which may offer a thoughtful benefits to patients with acute myocardial infarction and no complications. Nevertheless, several doubts exist as to whether IHH is a really safe technique, with little to no complications in post-myocardial infarction patients. Intermittent hypobaric hypox…
Screening for Low Energy Availability in Male Athletes: Attempted Validation of LEAM-Q
2022
A questionnaire-based screening tool for male athletes at risk of low energy availability (LEA) could facilitate both research and clinical practice. The present options rely on proxies for LEA such screening tools for disordered eating, exercise dependence, or those validated in female athlete populations. in which the female-specific sections are excluded. To overcome these limitations and support progress in understanding LEA in males, centres in Australia, Norway, Denmark, and Sweden collaborated to develop a screening tool (LEAM-Q) based on clinical investigations of elite and sub-elite male athletes from multiple countries and ethnicities, and a variety of endurance and weight-sensiti…