Search results for "united kingdom"
showing 10 items of 145 documents
Archibald Philip Primrose, V Earl of Rosebery 1894-1895 - Un “imperialista liberale”
2020
.La figura di Archibald Philip Primrose, complessa e contraddittoria, può considerarsi lo specchio dell’epoca in cui visse, a cavallo delle grandi rivoluzioni e delle profonde trasformazioni che avrebbero caratterizzato il secolo del ‘900, Uomo di grande cultura e di rara brillantezza intellettuale, fu partecipe dei governi di W. Gladstone, fino a divenire Premier nel 1894, per volere della Regina Vittoria. La sua natura aristocratica ma aperta lo portò, prima degli altri liberali, a percepire l’esigenza di un cambiamento di atteggiamento della Gran Bretagna verso le sue colonie, proponendosi come guida gentile e non oppressiva, espressione di un imperialismo moderno e sensato. Allo stesso …
A homozygous mutation in the TUB gene associated with retinal dystrophy and obesity.
2013
Inherited retinal dystrophies are a major cause of childhood blindness. Here, we describe the identification of a homozygous frameshift mutation (c.1194_1195delAG, p.Arg398Serfs*9) in TUB in a child from a consanguineous UK Caucasian family investigated using autozygosity mapping and whole-exome sequencing. The proband presented with obesity, night blindness, decreased visual acuity, and electrophysiological features of a rod cone dystrophy. The mutation was also found in two of the proband's siblings with retinal dystrophy and resulted in mislocalization of the truncated protein. In contrast to known forms of retinal dystrophy, including those caused by mutations in the tubby-like protein …
English and French Modes of Regulation of the Education System : a comparison
2003
03069; International audience; This paper describes English and French modes of regulation of the educational system, stressing the contrast between them (regulation by process versus regulation by outcomes), while their goals and organisation prove rather more convergent over the last 30 years. It tries to assess the correspondence between those two ways of operating and what we know about the functioning of organisations like schools. From that point of view, the French system fits the economic theory of organisation less well than the English one, so that some contradictions and tensions are predictable. Last, it looks for some relationhip with indicators of effectiveness, equity and soc…
The association of physical multimorbidity with suicidal ideation and suicide attempts in England: A mediation analysis of influential factors
2022
Background: Suicide is one of the most important causes of deaths in the United Kingdom, and the numbers are currently increasing. Aim: There are numerous identified determinants of suicidality, and physical multimorbidity is potentially important but is currently understudied. Thus, this study aims to investigate the association of physical multimorbidity with suicidality. Methods: Cross-sectional data from the Adult Psychiatric Morbidity Survey 2007, which was conducted in England between October 2006 and December 2007 by the National Center for Social Research and Leicester University were analyzed. Respondents were asked about 20 physical health conditions, and suicidal ideation and sui…
Development and psychometric evaluation of the Anticipated Food Scarcity Scale (AFSS).
2021
Mass media extensively inform societies about events threatening the global food supply (e.g., pandemics or Brexit). Consumers exposed to such communication may perceive food resources as becoming scarcer. In line with the evolutionary account, these perceptions can shift decision-making in domains such as food preferences or prosociality. However, the current literature has solely focused on actual and past food insecurity experiences threatening mostly low-income families, thus neglecting the future-oriented perceptions among the general population. This paper broadens the food insecurity research scope by developing a new construct—anticipated food scarcity (AFS)—which is defined as the …
Two pathways, one patient; UK asthma guidelines
2018
The first widely disseminated ‘asthma guideline’ came out of Australia and New Zealand in 1989,1 followed shortly by the British Thoracic Society (BTS) in 1990,2 the United States National Heart, Lung, and Blood Institute Expert Panel Report in 19913 and the Global Initiative for Asthma (GINA) strategy document in 1995.4 All have benefited from regular updates, the BTS collaborating with the Scottish Intercollegiate Guideline Network (SIGN) since 2003, most recently in 2016.5 Each new iteration of the asthma guidelines was written by experts in the field and based on best available evidence. It is not known whether these guidelines (or any others) have improved the care of people with asthm…
A comprehensive evaluation of potential lung function associated genes in the SpiroMeta general population sample
2011
Lung function measures are heritable traits that predict population morbidity and mortality and are essential for the diagnosis of chronic obstructive pulmonary disease (COPD). Variations in many genes have been reported to affect these traits, but attempts at replication have provided conflicting results. Recently, we undertook a meta-analysis of Genome Wide Association Study (GWAS) results for lung function measures in 20,288 individuals from the general population (the SpiroMeta consortium). OBJECTIVES: To comprehensively analyse previously reported genetic associations with lung function measures, and to investigate whether single nucleotide polymorphisms (SNPs) in these genomic regions…
Papers on the Conservation of Ancient Monuments and Remains. John Ruskin, Gilbert Scott e la Carta inglese della Conservazione (Londra, 1865)
2019
Il contributo tratta l'evoluzione storico-teorica del Restauro nel Regno Unito durante il XIX secolo, rilevando i fondamentali contributi che condurranno per la prima volta alla diffusione di una carta del Restauro, ovvero i "Papers on the Conservation of Ancient Monuments and Remains", pubblicata a Londra nel 1865. La ricerca si avvia chiarendo il significato che Edward August Freeman aveva paradossalmente assegnato al termine "conservazione" e, attraverso il supporto di documenti originali e nuove traduzioni, evidenzia il contributo fondamentale di George Gilbert Scott nella riformulazione conservativa degli obiettivi del restauro degli antichi edifici, con molti riferimenti alle idee di …
Suicide and Ambient Temperature: A Multi-Country Multi-City Study
2019
Background: Previous literature suggests that higher ambient temperature may play a role in increasing the risk of suicide. However, no multi-country study has explored the shape of the association and the role of moderate and extreme heat across different locations. Objectives: We examined the short-term temperature–suicide relationship using daily time-series data collected for 341 locations in 12 countries for periods ranging from 4 to 40 y. Methods: We conducted a two-stage meta-analysis. First, we performed location-specific time-stratified case-crossover analyses to examine the temperature–suicide association for each location. Then, we used a multivariate meta-regression to combine t…
Il ruolo della cultura inglese nella definizione del restauro come disciplina
2013
Il capitolo V nel volume Restauro Anno Zero (a cura di Francesco Tomaselli) evidenzia il contributo della cultura inglese alla definizione del Restauro come disciplina e rende noti in Italia documenti finora non tradotti, tra cui le "Carte della Conservazione dei Monumenti e dei Resti Antichi" valide in tutto il Regno Unito (1862 prima vers.), i documenti della SPAB e alcune lettere di William Morris. I margini temporali vanno dai primi studi del sito preistorico di Stonehenge (anni '60 del XVIII sec.) alla fondazione del National Trust (1895, da un'idea di John Ruskin). La ricerca, in particolare, offre approfondimenti originali sulla protesta internazionale avviata nel 1879 dalla Society …