Search results for "unity"
showing 10 items of 3852 documents
Dynamic Community Detection for Brain Functional Networks during Music Listening with Block Component Analysis
2023
Publisher Copyright: Author The human brain can be described as a complex network of functional connections between distinct regions, referred to as the brain functional network. Recent studies show that the functional network is a dynamic process and its community structure evolves with time during continuous task performance. Consequently, it is important for the understanding of the human brain to develop dynamic community detection techniques for such time-varying functional networks. Here, we propose a temporal clustering framework based on a set of network generative models and surprisingly it can be linked to Block Component Analysis to detect and track the latent community structure…
The Relationships Between Customer Brand Engagement in Social Media and Share of Wallet
2016
This chapter investigates the motivational drivers of customer brand engagement in social media and examines the nature of the relationships between these drivers and engagement, as well as the relationships between brand engagement and share-of-wallet. In addition, we tested the moderating effect of the frequency of social media visits on the relationship between engagement and share-of-wallet. The hypothesized relationships were analyzed using an online survey of 818 members of one Facebook brand community. The results suggested that community exerts the strongest positive effect on customer brand engagement and that customer brand engagement positively influences SOW. The findings also i…
Perfluoroalkyl substances in Breast milk, infant formula and baby food from Valencian Community (Spain)
2016
Environmental and human exposures to perfluoroalkyl substances (PFASs) are of emerging concern since they are persistent and bioaccumulative. The present study reports PFASs levels in human milk, infant formulas and baby food (dry cereals and pots) from the Valencian Community (Spain) in order to evaluate the infant exposure to these substances through the diet. The results show that perfluorobutanoic acid (PFBA) and perfluorooctanoic acid (PFOA) were in all the samples of the four selected matrices (except PFOA in one sample of dry cereal baby food). Perfluoroheptanoic acid (PFHpA) and perfluorodecanoic acid (PFDA) were also detected in 70% of the breast milk samples. In infant formulas, P…
Investigating Centrality Measures in Social Networks with Community Structure
2021
Centrality measures are crucial in quantifying the influence of the members of a social network. Although there has been a great deal of work dealing with this issue, the vast majority of classical centrality measures are agnostic of the community structure characterizing many social networks. Recent works have developed community-aware centrality measures that exploit features of the community structure information encountered in most real-world complex networks. In this paper, we investigate the interactions between 5 popular classical centrality measures and 5 community-aware centrality measures using 8 real-world online networks. Correlation as well as similarity measures between both t…
Cigarette smoke alters IL-33 expression and release in airway epithelial cells
2014
AbstractAirway epithelium is a regulator of innate immune responses to a variety of insults including cigarette smoke. Cigarette smoke alters the expression and the activation of Toll Like Receptor 4 (TLR4), an innate immunity receptor. IL-33, an alarmin, increases innate immunity Th2 responses. The aims of this study were to explore whether mini-bronchoalveolar lavage (mini-BAL) or sera from smokers have altered concentrations of IL-33 and whether cigarette smoke extracts (CSE) alter both intracellular expression (mRNA and protein) and release of IL-33 in bronchial epithelial cells. The role of TLR4 in the expression of IL-33 was also explored.Mini-BALs, but not sera, from smokers show red…
Per un’educazione universale. La via del Buddhismo nelle società post-secolari
2018
The paper examines Buddhism as a religion that suggests to the post-modern and post-secular West a new, inclusive, non-violent and ecological education. It proposes an universal education that responds to the request of religiosity of our societies. Buddhism is investigated as a millennial pedagogy, in which the path of spiritual growth coincides with a path of self-education that is articulated through an interior and social education. The center of the Buddhist doctrine is the meditation (dhyan), that leads the disciple, with the support of a master and the community, for a rebirth that, declaring him as the author of his own realization, leads him to establish empathic relationship with …
Th17 immunity in children with allergic asthma and rhinitis: a pharmacological approach
2013
Th17 cells and IL-17A play a role in the development and progression of allergic diseases. We analyzed the IL-17A levels in sputum supernatants (Ss), nasal wash (NW) and plasma (P) from Healthy Controls (HC) and children with Asthma/Rhinitis. We tested the expression of IL-17A, RORγ(t) and FOXP3 in peripheral blood T-lymphocytes from intermittent and mild-moderate asthma. The effect of Budesonide and Formoterol was tested "in vitro" on IL-17A, RORγ(t) and FOXP3 expression in cultured T-lymphocytes from mild-moderate asthma/persistent rhinitis patients, and on nasal and bronchial epithelial cells stimulated with NW and Ss from mild-moderate asthma/persistent rhinitis. Further, the effect of …
Il dolore comune. Butler dopo Kant
2019
The author shows how the political reflexion of Butler is a radicalisation of the Kantian one. The theme of pain ,which Heidegger already debated on a rational and non-emotional basis, constitutes for the philosopher the point from which you start to think about the community today.
CTCF and BORIS Regulate Rb2/p130 Gene Transcription: A Novel Mechanism and a New Paradigm for Understanding the Biology of Lung Cancer
2011
Abstract Although innumerable investigations regarding the biology of lung cancer have been carried out, many aspects thereof remain to be addressed, including the role played by the retinoblastoma-related protein Rb2/p130 during the evolution of this disease. Here we report novel findings on the mechanisms that control Rb2/p130 gene expression in lung fibroblasts and characterize the effects of Rb2/p130 deregulation on the proliferative features of lung cancer cells. We revealed for the first time that in lung fibroblasts the expression of Rb2/p130 gene is directly controlled by the chromatin insulator CCCTC-binding factor, CTCF, which by binding to the Rb2/p130 gene promoter induces, and/…
The Cytokine GM-CSF Drives the Inflammatory Signature of CCR2+ Monocytes and Licenses Autoimmunity.
2015
Granulocyte-macrophage colony-stimulating factor (GM-CSF) has emerged as a crucial cytokine produced by auto-reactive T helper (Th) cells that initiate tissue inflammation. Multiple cell types can sense GM-CSF, but the identity of the pathogenic GM-CSF-responsive cells is unclear. By using conditional gene targeting, we systematically deleted the GM-CSF receptor (Csf2rb) in specific subpopulations throughout the myeloid lineages. Experimental autoimmune encephalomyelitis (EAE) progressed normally when either classical dendritic cells (cDCs) or neutrophils lacked GM-CSF responsiveness. The development of tissue-invading monocyte-derived dendritic cells (moDCs) was also unperturbed upon Csf2r…