Search results for "unmet needs"
showing 10 items of 31 documents
EPA-1513 - Utilization of health care among people with depression in Latvia
2014
Background Depression is highly prevalent and disabling mental disorder, less than one third of all cases receive any treatment, suggesting a remarkable level on unmet needs. Aim The aim of the study was to assess differences in health care utilization among people with depression and those with no symptoms in representative sample of the general Latvian population. Methods The study was a part of the FINBALT health monitoring survey in 2012, a collaborative project between Baltic States and Finland, which monitors health related behaviours; the questionnaire included depression module of the Mini International Neuropsychiatric Interview (MINI). A total of 3003 15-64 years old persons were …
'What can I do? Any tips?' Online communities and agoraphobia, an open channel for shared participation in management of medical treatment
2021
espanolEn este articulo se analizan las entradas producidas en tres grupos de la red social Facebook creados y utilizados por personas diagnosticadas de agorafobia mediante un analisis del discurso. Se identifica que las comunidades virtuales constituyen espacios que favorecen la emergencia de un posicionamiento activo de sus participantes en la co-gestion de su medicacion a partir de tres ejes: a) espacio extra-medico de iguales que favorece el intercambio de informacion, la formacion y la consulta; b) espacio que posibilita el nacimiento y puesta en comun de narrativas alternativas a la farmacologica, y; c) espacio de conflicto entre narrativas sobre la medicacion que, en algunos casos, f…
Treatment of Hepatitis C virus infection in Italy: A consensus report from an expert panel
2017
Abstract Hepatitis C virus (HCV) infection remains one of the main causes of chronic liver disease worldwide. The advent of direct-acting antivirals (DAAs) has significantly improved the course of patients with chronic HCV infection (CHC), due to the ability of these drugs to achieve high rates of sustained virological response (SVR). These exceedingly high rates of SVR and the excellent safety data have been confirmed in real life practice. Evolving guidelines have been issued by national and international scientific societies in accordance with the progression of clinical knowledge and the availability of new DAAs. These recommendations, however, may not be applied universally because of …
Unmet care needs are common among community-dwelling older people with memory problems in Finland
2019
Aims: Ageing in place has become a policy priority. Consequently, residential care has been reduced, and more older people with multiple care needs reside at home with the help of informal care and home care services. An increasing share of these people has memory disorders. We examined the extent to which memory problems, in addition to other individual characteristics, are associated with unmet care needs among community-dwelling older people. Methods: The study employed cross-sectional survey data from community-dwelling people aged 75+ collected in 2010 and 2015, analysed using binary logistic regression analysis. The study population consisted of people who had long-term illnesses or …
Patient-reported impact of Charcot-Marie-Tooth disease: protocol for a real-world digital lifestyle study
2021
Abstract Background Charcot-Marie-Tooth disease (CMT) is a rare, chronic, progressive motor and sensory neuropathy that affects the peripheral nervous system, leading to progressive, predominantly distal muscle weakness, atrophy, sensory loss and progressive limb dysfunction. As with many rare diseases, there is a lack of patient-reported data with which to understand and address patient needs. This study aims to explore the real-world impact of CMT from the patient perspective. Methods This is a prospective, digital lifestyle study of at least 2,000 people with CMT, >18 years, resident in the following countries: France, Germany, Italy, Spain, the UK and the USA. Participants will be re…
ATTENTUS, a German online survey of patients with chronic urticaria highlighting the burden of disease, unmet needs and real-life clinical practice.
2015
A prognostic miRNA based signature in early-stage HER2-positive breast cancer patients.
2021
e12600 Background: In early-stage HER2+ breast cancer (BC), escalation or de-escalation of systemic treatment is an unmet need. Integration of promising biomarkers into risk scoring will further help progressing in the field. We aim to develop a prognostic signature that integrates two miRNAs (A and B) and quantitative and qualitative clinical variables in patients diagnosed with HER2+ BC. Methods: This study was conducted in a retrospective cohort of 45 HER2+ BC patients. Patients received standard treatment for localized disease. We calculated a prognostic signature for disease-free survival (DFS) using principal components analysis for mixed data combining clinicopathological data (Ki67…
Biology and significance of alpha‐fetoprotein in hepatocellular carcinoma
2019
Hepatocellular carcinoma (HCC) is one of the most common causes of cancer-related deaths globally due, in part, to the majority of patients being diagnosed with intermediate or advanced stage disease. Our increased understanding of the heterogeneous molecular pathogenesis of HCC has led to significant developments in novel targeted therapies. Despite these advances, there remains a high unmet need for new treatment options. HCC is a complex disease with multiple pathogenic mechanisms caused by a variety of risk factors, making it difficult to characterize with a single biomarker. In fact, numerous biomarkers have been studied in HCC, but alpha-fetoprotein (AFP) remains the most widely used …
Propiedades Psicométricas de la Versión Española del Cancer Survivors¿ Unmet Needs (CaSUN-S) en Cáncer de Mama
2021
[ES] el Cancer Survivors¿ Unmet Needs (CaSUN) ha sido desarrollado para esta población, pero varias cuestiones sobre sus propiedades estructurales permanecen inconclusas. Método: este estudio prueba el modelo teórico, la solución empírica de los autores originales y una nueva propuesta racional del CaSUN utilizando Análisis Factorial Confi rmatorio; también analiza su fi abilidad y validez convergente. 566 supervivientes de cáncer de mama completaron el CaSUN, el Inventario Breve de Síntomas-18 (BSI-18) y el Quality of Life in Adult Cancer Survivors (QLACS). Resultados: el modelo propuesto de cinco dominios (efectos físicos, efectos psicológicos, atención integral e información, cuestiones …
Palliative Care Needs and Integration of Palliative Care Support in COPD
2021
Background The provision of palliative care for severe COPD remains low, resulting in unmet needs in patients and carers. Research Questions What are the palliative care needs of patients living with severe COPD and their caregivers? What views of accessing and providing palliative care and factors influence these experiences. To what extent have palliative care and COPD services been integrated? Study Design and Methods A multicentre qualitative study was undertaken in COPD services and specialist palliative care in the United Kingdom involving patients with severe COPD, their carers, and health professionals. Data were collected using semistructured interviews and were analyzed using fram…