Search results for "urea"

showing 10 items of 888 documents

Synthesis and evaluation of (S)-2-(2-[18F]fluoroethoxy)-4-([3-methyl-1-(2-piperidin-1-yl-phenyl)-butyl-carbamoyl]-methyl)-benzoic acid ([18F]repaglin…

2004

18F-labeled non-sulfonylurea hypoglycemic agent (S)-2-(2-[(18)F]fluoroethoxy)-4-((3-methyl-1-(2-piperidin-1-yl-phenyl)-butylcarbamoyl)-methyl)-benzoic acid ([(18)F]repaglinide), a derivative of the sulfonylurea-receptor (SUR) ligand repaglinide, was synthesized as a potential tracer for the non-invasive investigation of the sulfonylurea 1 receptor status of pancreatic beta-cells by positron emission tomography (PET) in the context of type 1 and type 2 diabetes. [(18)F]Repaglinide could be obtained in an overall radiochemical yield (RCY) of 20% after 135 min with a radiochemical purity higher than 98% applying the secondary labeling precursor 2-[(18)F]fluoroethyltosylate. Specific activity w…

Fluorine RadioisotopesCancer ResearchBiodistributionMetabolic Clearance RateReceptors DrugContext (language use)Sulfonylurea ReceptorsRats Sprague-DawleyIslets of Langerhanschemistry.chemical_compoundPiperidinesmedicineRadioligandAnimalsTissue DistributionRadiology Nuclear Medicine and imagingPotassium Channels Inwardly RectifyingBenzoic acidChemistryBiological activityLigand (biochemistry)RepaglinideRatsDissociation constantBiochemistryOrgan SpecificityRats Inbred LewIsotope LabelingPositron-Emission TomographyFeasibility StudiesMolecular MedicineATP-Binding Cassette TransportersCarbamatesMultidrug Resistance-Associated ProteinsRadiopharmaceuticalsNuclear chemistrymedicine.drugNuclear Medicine and Biology
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Synthesis and first evaluation of new 18F-labelled sulfonylureas for the determination of the beta-cell status in vivo

2001

The syntheses and first in vitro evaluations for two fluoride bearing sulfonylurea derivatives are reported. Firstly, the tolbutamide derivative 1-[4-(2-[18F]fluoroethoxy)benzenesulfonyl]-3-butyl urea (2-[18F]fluoroethyl-tolbutamide) could be labeled efficiently with [18F]fluoride. Subsequently, the glibenclamid derivative N-(2-(4-(N-((cyclohexylamino)carbonyl)sulfonylamino)phenyl)ethyl) 2-(5-chloro-2-[18F]fluorethoxy)phenyl) formamide (2-[18F]fluoroethyl-glibenclamide) was labeled with [18F]fluoride in high yields. Its ability to induce insuline secretion from rat beta-cells in relation to the original glibenclamide was determined.

FormamideStereochemistrymedicine.drug_classOrganic ChemistryBiochemistrySulfonylureaIn vitroAnalytical ChemistryGlibenclamidechemistry.chemical_compoundTolbutamidechemistryIn vivoDrug DiscoveryUreamedicineRadiology Nuclear Medicine and imagingFluorideSpectroscopymedicine.drugJournal of Labelled Compounds and Radiopharmaceuticals
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Lygus rugulipennis on chrysanthemum : Supplemental prey effects and an evaluation of trap plants

2022

The European tarnished plant bug, Lygus rugulipennis Poppius, is considered a major pest in chrysanthemum nurseries in The Netherlands. Adults puncture plant's apical meristem, after which the growing point splits and growth is inhibited. Flower buds and flowers can also be severely damaged. Both types of damage result in economic losses for growers. Despite the importance of this pest for chrysanthemum nurseries, there is only very limited information about L. rugulipennis development on chrysanthemum plants, Chrysanthemum × morifolium Ramat., and whether L. rugulipennis can be controlled using trap plants is not known. We investigated whether: (1) L. rugulipennis could develop from egg to…

GTB Bedrijfsbureauintegrated pest managementGTB Gewasgez. Bodem en WaterMyzus persicaeEuropean tarnished plant bugPE&RCEphestia kuehniella European tarnished plant bug horticultural pest integrated pest management Myzus persicae Sinapis albaCrop healthhorticultural pestInsect ScienceGewasgezondheidSinapis albaAgronomy and Crop ScienceEphestia kuehniellaJournal of Applied Entomology
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Agro roig, Garza imperial (VER0000066)

1934

Altres noms vulgars: Purple Heron (Anglès), Héron pourpré (Francès), Purpurreiher-purpurea (Alemany) Gabinet de Vertebrats (Departament de Zoologia), Facultat de Ciències Biològiques (Campus de Burjassot), C/ Doctor Moliner, s/n, Bloque B. 5é plant, Burjassot (Valencia). Armari: 11-1 La Albufera 1934 Prenupcial purpurea _

Garzas garcetas avetoros cigüeñas íbises y espátulasArdeidaeArdea purpurea (Linnaeus 1766)
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Agro roig, Garza imperial (VER0000194)

Purple Heron (Anglès), Héron pourpré (Francès), Purpurreiher-purpurea (Alemany) Gabinet de Vertebrats (Departament de Zoologia), Facultat de Ciències Biològiques (Campus de Burjassot), C/ Doctor Moliner, s/n, Bloque B. 5é plant, Burjassot (Valencia). Armari: 11-1 La Albufera (Valencia)/Cartagena Juvenil Juvenil purpurea _

Garzas garcetas avetoros cigüeñas íbises y espátulasArdeidaeArdea purpurea (Linnaeus 1766)
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Ikivėžinių skrandžio gleivinės pokyčių paplitimas Helicobacter pylori sukelto lėtinio gastrito metu tarp Rytų Europos (Lietuvos, Latvijos) ir Azijos …

2007

The aim of the study was to compare the prevalence and severity of precancerous condition – gastric atrophy and intestinal metaplasia (IM) between Eastern European (Lithuania and Latvia) and Asian (Taiwan) countries in population older than 55 years. Methods. Patients aged 55 years and older, referred for upper endoscopy due to dyspeptic symptoms, were included in the study. Gastric biopsies were histological investigated according modified Sydney classification. Helicobacter pylori (H. pylori) was detected if any two of three methods (urease test, histology, and serology) were positive. Results. Overall 322 patients included: 52 from Taiwan (TW), 171 from Latvia (LV) and 99 from Lithuania …

Gastritis AtrophicMalemedicine.medical_specialty616.3 [udc]Helicobacter pylori ; Gastritis atrophic ; Intestinal diseases ; Metaplasia ; Precancerous conditionsBiopsyPopulationTaiwanRapid urease testintestinal metaplasiaGastroenterologyHelicobacter InfectionsAtrophyStomach NeoplasmsMetaplasiaInternal medicineGastroscopyPrevalenceHumansMedicineeducation616.33/.34 [udc]AgedMetaplasiaeducation.field_of_studyHelicobacter pyloribiologybusiness.industryStomachgastritisIntestinal metaplasia<em>Helicobacter pylori</em>; gastritis; atrophy; intestinal metaplasiaLithuaniaGeneral MedicineMiddle AgedHelicobacter pylorimedicine.diseasebiology.organism_classificationLatviaEastern europeanFemaleAtrophymedicine.symptomGastritisbusinessPrecancerous Conditions<em>Helicobacter pylori</em>
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¿Cómo deciden les jóvenes la transición a la educación postobligatoria? Diferencias entre centros públicos y privados-concertados

2017

Background of INCASI Project H2020-MSCA-RISE-2015 GA 691004. WP1: Compilation El objetivo del presente artículo es examinar el papel que juega la titularidad del centro en el que se cursa la educación secundaria obligatoria (ESO) en la decisión de transitar a la educación postobligatoria. En dicha encrucijada se contemplan también otras variables que se han constatado de gran peso en la toma de decisión como son las notas previas obtenidas, el nivel formativo familiar, el sexo, las expectativas y las aspiraciones, partiendo del modelo decisional de transiciones educativas[1] que contempla el modelo de Boudon sobre los efectos primarios y secundarios. Los resultados obtenidos son los derivad…

General MedicineSecondary educationTransiciónExpectations:SOCIOLOGÍA [UNESCO]Educació secundària obligatòriaEleccionesChoicesTitularidad del centroNotasUNESCO::SOCIOLOGÍATransitionGradesBatxilleratBaccalaureate (Secondary school educational programme)School ownershipExpectativas
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Assessing the genetic diversity ofCentaurea parlatorisgroup (sect.Dissectae, Compositae) in Sicily using isozymes

2011

Abstract The Centaurea parlatoris group belongs to sect. Dissectae and is one of the most taxonomically critical groups in Sicily. The taxa included in it inhabit dry slopes, pastures and rocky places. Some of them are narrow endemics to Sicily, and others to Italy. The great morphological variability at the intrapopulation level has not permitted the creation of an adequate taxonomic scheme. The recent proposal of two new species from Sicily confirms the insufficient knowledge of the taxonomic diversity. This study involves eight Sicilian populations of the C. parlatoris group. Seven loci from nine enzyme systems [isocitrate dehydrogenase (IDH), malate dehydrogenase (MDH), 6-phosphoglucona…

Genetic diversitybiologyPlant Sciencebiology.organism_classificationMalate dehydrogenaselanguage.human_languageIsocitrate dehydrogenaseTaxonCentaureaCentaurea endemics genetic diversity isozyme SicilyBotanylanguagePhosphoglucomutaseEndemismSicilianEcology Evolution Behavior and SystematicsPlant Biosystems - An International Journal Dealing with all Aspects of Plant Biology
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Evaluation of genetic variability and relatedness among eight Centaurea species through CAAT-box derived polymorphism (CBDP) and start codon targeted…

2021

Centaurea is a value-ultimate genus of medicinal plants showing high diversification levels, especially within the Mediterranean basin, and is still traditionally recognized as a complicated taxon. So far, few studies utilizing molecular markers have been done on Centaurea spp. towards a better dissection of its phylogeny and accurate assessment of genetic diversity. Here, two functional marker systems, start codon targeted (SCoT) polymorphism and CAAT box-derived polymorphism (CBDP), were implemented to assess the genetic diversity between eight wild Centaurea species in Egypt. Seventeen SCoT and 19 CBDP primers generated 197 and 179 bands, respectively. These primers generated 158 (80.2%)…

Genetic diversitybiologymolecular markersfungicentaureagenetic diversitybiology.organism_classificationMediterranean BasinTaxonStart codonpcrCentaureaEvolutionary biologyGenusPolymorphism (computer science)cbdpscotGenetic variabilityTP248.13-248.65BiotechnologyBiotechnology & Biotechnological Equipment
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A Model for Assessing the Performance of Bureaucracy in Spain

2000

The aim of this paper is to put forward a simplified model which may help to explain the workings and performance of public entities in Spain. Starting from a bilateral monopoly characterization, we shall take into account the working rules, the decision-making mechanisms and the system of rewards and penalties in Spanish public administrations. This implies introducing different assumptions about the demand and the costs conditions what will lead us obtain meaningful distinct results from those reached in the standard models of bureaucratic behavior.

GeographyPublic Administrationmedia_common.quotation_subjectBureaucracyPublic administrationGeneral Economics Econometrics and Financemedia_commonJournal of Public Finance and Public Choice
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