Search results for "urea"

showing 10 items of 888 documents

Molecular diagnostic of Ureaplasma urealyticum presence and tetracycline resistance in urine samples

2021

Abstract Sexually transmitted infections (STIs) are among the most common infections in Romania. Infection with Ureaplasma urelyticum is one of the major causes of STIs and can cause serious complications. Although tetracycline is the drug commonly used to treat infections caused by U. urealyticum, several studies indicate the emergence and rapid development of strains resistant to these antibiotics in the United States or Europe. Tetracycline resistance in bacteria is encoded by a number of different genetic determinants but in mycoplasmas the only tetracycline resistance determinant that has been reported is the tetM gene. Tetracycline resistance among Ureaplasma spp. is associated with t…

0301 basic medicineTetracyclinebusiness.industry030106 microbiologyRUrinemedicine.disease_causeurologic and male genital diseasesfemale genital diseases and pregnancy complicationsMicrobiologytetm gene03 medical and health sciences0302 clinical medicinetetracycline-resistantpcrureaplasma urelyticummedicineMedicine030212 general & internal medicineurease genebusinessmedicine.drugUreaplasma urealyticumRomanian Journal of Laboratory Medicine
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Ryanodine receptor- and sodium-calcium exchanger-mediated spontaneous calcium activity in immature oligodendrocytes in cultures

2019

Myelination in the central nervous system depends on interactions between axons and oligodendrocyte precursor cells (OPCs). Action potentials in an axon can be followed by release of biologically active substances, like glutamate, which can instruct OPCs to start myelination. Myelin Basic Protein (MBP) is an "executive molecule of myelin" required for the formation of compact myelin. As cells of the oligodendrocyte lineage (OLCs) are capable of producing MBP in pure oligodendrocyte cultures, i.e. without neurons, we investigated Ca2+ signaling in developing OLCs in cultures. We show that spontaneous Ca2+ transients (CTs) occur at very low frequency in both bipolar OPCs and mature oligodendr…

0301 basic medicineThapsigarginSodium-Calcium Exchanger03 medical and health scienceschemistry.chemical_compoundMyelin0302 clinical medicineCompact myelinmedicineAnimalsCalcium SignalingAxonOuabainCells CulturedMyelin SheathNeuronsbiologySodium-calcium exchangerChemistryRyanodine receptorGeneral NeuroscienceSodiumThioureaRyanodine Receptor Calcium Release ChannelOligodendrocyteMyelin basic proteinCell biologyMice Inbred C57BLOligodendroglia030104 developmental biologymedicine.anatomical_structurenervous systembiology.proteinCalcium030217 neurology & neurosurgeryNeuroscience Letters
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Iron-loaded transferrin (Tf) is detrimental whereas iron-free Tf confers protection against brain ischemia by modifying blood Tf saturation and subse…

2018

Despite transferrin being the main circulating carrier of iron in body fluids, and iron overload conditions being known to worsen stroke outcome through reactive oxygen species (ROS)-induced damage, the contribution of blood transferrin saturation (TSAT) to stroke brain damage is unknown. The objective of this study was to obtain evidence on whether TSAT determines the impact of experimental ischemic stroke on brain damage and whether iron-free transferrin (apotransferrin, ATf)-induced reduction of TSAT is neuroprotective. We found that experimental ischemic stroke promoted an early extravasation of circulating iron-loaded transferrin (holotransferrin, HTf) to the ischemic brain parenchyma.…

0301 basic medicineU-PAGE urea-polyacrylamide gel electrophoresisMaleClinical BiochemistryExperimental strokeBiochemistryBrain IschemiaBrain ischemia0302 clinical medicineADC apparent diffusion coefficientApotransferrinDWI diffusion-weighted imagingTANDEM-1 Thrombolysis and Deferoxamine in Middle Cerebral Artery Occlusion clinical trialrHTf rat HTfrATf rat ATflcsh:QH301-705.5chemistry.chemical_classificationNeuronslcsh:R5-920ChemistryTransferrinExtravasationNS21 a medium supplement to grow neuronspDAPK-1 phosphorylated anti-death-associated protein kinase 1NeuroprotectionStrokeWB Western blotFemalemedicine.symptomlcsh:Medicine (General)Research PaperhHTf human HTfPC12 cell line derived from a pheochromocytoma of the rat adrenal medullamedicine.medical_specialtyIron OverloadBBB blood-brain barrierNMDAR N-methyl-D-aspartate receptorDCF dihydrofluoresceinIronWGA wheat germ agglutininHTf holotransferrinTransferrin receptorBrain damageTfR transferrin receptorDeferoxamineNeuroprotectionPI propidium iodide03 medical and health sciencesBrain damageCM conditioned mediumROS reactive oxygen speciesInternal medicine4-HNE 4-hydroxynonenalTf transferrinReceptors TransferrinmedicineFeRhoNoxTM-1 probe to detect Fe2+AnimalsHumansATf apotransferrinCM-H2DCFDA 5-chloromethyl-27-dichlorodihydrofluorescein diacetateMCAO middle cerebral artery occlusionDMT-1 divalent metal transporterB-27 a medium supplement to grow neuronsReactive oxygen speciesNMDA N-methyl-D-aspartateTSAT blood transferrin saturationTransferrin saturationBlood transferrin saturation (TSAT)Organic ChemistryNIR near infraredReactive oxygen species (ROS)medicine.diseasepMCAO permanent middle cerebral artery occlusionRatsPWI perfusion-weighted imaging030104 developmental biologyEndocrinologylcsh:Biology (General)TransferrinDAPK-1 anti-death-associated protein kinaseOGD oxygen/glucose deprivationTTC 235-triphenyl-tetrazolium chlorideLipid PeroxidationMCA middle cerebral arteryApoproteinsReactive Oxygen SpeciesMRI magnetic resonance imagingtMCAO transient middle cerebral artery occlusion030217 neurology & neurosurgeryhATf human ATf
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Pasta Supplemented with Opuntia ficus-indica Extract Improves Metabolic Parameters and Reduces Atherogenic Small Dense Low-Density Lipoproteins in Pa…

2020

Food supplementation with Opuntia ficus-indica (OFI) has been associated with a significant reduction in total cholesterol, body fat, hyperglycemia and blood pressure. Since OFI may also have antioxidant and anti-atherogenic properties, we hypothesized that its supplementation might reduce atherogenic lipoproteins, including small, dense low-density lipoproteins (sdLDL). Forty-nine patients (13 men and 36 women, mean age: 56 &plusmn

0301 basic medicinecardiovascular riskmedicine.medical_specialtyOpuntia ficus-indicaAntioxidantWaistEndocrinology Diabetes and Metabolismmedicine.medical_treatmentlcsh:QR1-502Aspartate transaminase030204 cardiovascular system & hematologyPolysaccharideBiochemistrylcsh:MicrobiologyArticle03 medical and health scienceschemistry.chemical_compound0302 clinical medicineInternal medicinemedicineMolecular Biologychemistry.chemical_classificationnutraceuticalslow-density lipoprotein cholesterol030109 nutrition & dieteticsbiologybusiness.industrydyslipidemiamedicine.disease<i>Opuntia ficus-indica</i>EndocrinologyBlood pressurechemistryUreabiology.proteinMetabolic syndromebusinessDyslipidemia
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Human Breast Milk NMR Metabolomic Profile across Specific Geographical Locations and Its Association with the Milk Microbiota

2018

The composition of human breast milk is highly variable, and it can be influenced by genetics, diet, lifestyle, and other environmental factors. This study aimed to investigate the impact of geographical location and mode of delivery on the nuclear magnetic resonance spectroscopy (NMR) metabolic profile of breast milk and its relationship with the milk microbiome. Human milk metabolic and microbiota profiles were determined using NMR and 16S rRNA gene sequencing, respectively, in 79 healthy women from Finland, Spain, South Africa, and China. Up to 68 metabolites, including amino acids, oligosaccharides, and fatty acid-associated metabolites, were identified in the milk NMR spectra. The meta…

0301 basic medicinemode of deliveryMetaboliteRiboflavinCarboxylic AcidsOligosaccharidesmicrobiomeBacillusproton nuclear magnetic resonancechemistry.chemical_compoundSouth Africafluids and secretionsPregnancyMetabolitesUreaCaesarean sectionFood scienceAmino AcidsFinlandmetabolitesPhosphocholineNutrition and DieteticsProton nuclear magnetic resonanceMicrobiotaHuman milkfood and beverageshuman milkta3141ActinobacteriaMetabolomeFemalelcsh:Nutrition. Foods and food supplyAdultChinalcsh:TX341-641Breast milkta3111CreatineArticle03 medical and health sciencesYoung AdultMetabolomicsProteobacteriaMetabolomeHumansMetabolomicsMicrobiome030109 nutrition & dieteticsBacteriaMilk HumanCholesterol LDLDelivery Obstetric030104 developmental biologychemistrySpaincaesarean sectionMode of deliveryMicrobiomeBreast feedingFood ScienceNutrients
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Pain Education in Schools of Nursing: a Survey of the Italian Academic Situation.

2018

Introduction: Proper assessment of pain is imperative for the development of an effective pain management plan and is a core responsibility of nurses and healthcare professionals. This article describes the contents of Italian on-line bachelor's in nursing degree programs, with particular focus on pain management.Method: A descriptive study was made on curricula published and available on-line in Italian Nursing Schools, and the concordance with the standards set by the Consensus Curriculum on Pain for Nursing ofthe International Association for the Study of Pain (IASP, 2015) was analyzed.Results: Of all the bachelor programs published on-line, 42.6% offered programs and courses specificall…

030504 nursingSchools NursingBachelor in NursingEducation Nursing BaccalaureateGeneral MedicineSettore MED/45 - Scienze Infermieristiche Generali Cliniche E Pediatriche03 medical and health sciences0302 clinical medicineItalySurveys and QuestionnairesHumansPain ManagementpainCore-curriculumCurriculum0305 other medical sciencePsychologyHumanities030217 neurology & neurosurgeryProfessioni infermieristiche
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Professionalization as Status Adaptation: The Nobility, the Bureaucracy, and the Modernization of the Legal Profession in Finland

1991

In contrast to Anglo-American lines of professional development, the central agent of professionalization in many Continental countries was the state bureaucracy. However, this article proposes that an understanding of the class structure of traditional society is also needed to explain the privileged position of lawyers. An historical study of lawyers in the 19th century, after Finland was annexed by Russia, demonstrates that the legal profession provided the nobility an important medium of adaptation to the new society. The importance of the legal profession initially to the state bureaucracy, and subsequently to the nobility, explains its social prominence and its future development. An …

050502 lawmedia_common.quotation_subject05 social sciencesGeneral Social SciencesContext (language use)Modernization theoryProfessionalization0506 political scienceState (polity)NobilityLaw050602 political science & public administrationBureaucracySociologyLawLegal professionTraditional society0505 lawmedia_commonLaw &amp; Social Inquiry
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The social embeddedness of hydraulic engineers in the regulation of water and infrastructure in Peru

2019

Based on ethnographic fieldwork in the Majes-Colca watershed in Peru, this article explores some of the questions posed by Wittfogel regarding the management of hydraulic infrastructure and its eff...

060101 anthropologyWatershedPublic AdministrationEmbeddednessmedia_common.quotation_subject05 social sciencesGeography Planning and Development0507 social and economic geography06 humanities and the artsManagement Monitoring Policy and LawEnvironmental Science (miscellaneous)EconomyState (polity)Ethnography0601 history and archaeologyBureaucracySociology050703 geographySocialitymedia_commonEnvironment and Planning C: Politics and Space
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How to study bureaucracies ethnographically?

2019

We propose a short epistemological and methodological reflection on the challenges of doing ethnographical research on public services (‘bureaucracies’) from the inside. We start from the recognition of the double face of bureaucracy, as a form of domination and oppression as well as of protection and liberation, and all the ambivalences this dialectic entails. We argue that, in classical Malinowskian fashion, the anthropology of bureaucracy should take bureaucrat as the ‘natives’, and acknowledge their agency. This means adopting basic anthropological postures: the natives (i.e. the bureaucrats) must have good reasons for their seemingly ‘absurd’ (or arbitrary) practices, once you underst…

060101 anthropologymedia_common.quotation_subject05 social sciences0507 social and economic geography06 humanities and the artsEpistemologyArts and Humanities (miscellaneous)State (polity)AnthropologyEthnography0601 history and archaeologyBureaucracySociologyReflection (computer graphics)050703 geographymedia_commonCritique of Anthropology
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CCDC 1425258: Experimental Crystal Structure Determination

2016

Related Article: T. Mäkelä, K. Rissanen|2016|Dalton Trans.|45|6481|doi:10.1039/C6DT00414H

11'-(2356891112-Octahydro-1471013-benzopentaoxacyclopentadecine-1516-diyl)bis(3-(4-nitrophenyl)urea) NN-dimethylformamide solvateSpace GroupCrystallographyCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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