Search results for "urea"

showing 10 items of 888 documents

Volatile Components from Aerial parts of Centaurea diffusa and C. micrantha ssp. melanosticta and their biocidal activity on microorganisms affecting…

2018

The chemical composition of the essential oils from aerial parts of two taxa of Centaurea belonging to subgenus Acrolophus, Centaurea diffusa Lam. and C. micrantha Hoff. ssp. melanosticta (Lange) Dostàl, respectively collected in Croatia and Spain, were evaluated by GC and GC-MS. The main components of C. diffusa were hexadecanoic acid (31.1%), (Z,Z)-9,12-octadecadienoic acid (10.7%) and damascenone isomers (6.4%), whereas hexahydrofarnesyl acetone (27.8%), hexadecanoic acid (8.3%) and caryophyllene oxide (6.4%) were the most abundant components of C. micrantha ssp. melanosticta. The oils showed good antibacterial and antifungal activities against some microorganisms that infest historical …

12-Octadecadienoic acid Antimicrobial activity Asteraceae Centaurea diffusa Centaurea micrantha ssp. melanosticta Hexadecanoic acid Hexahydrofarnesyl acetone ZZ-9
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Ģimenes ārstu un speciālistu nozīmēto H.pylori eradikācijas shēmu salīdzinājums; to atbilstība vadlīnijām un efektivitāte

2016

Helicobacter pylori kolonizē kuņģa gļotādu vairāk nekā pusei pasaules iedzīvotāju. Pasaules Veselības organizācija ir pasludinājusi H. pylori par 1. grupas kancerogēno vielu. Latvijā H. pylori eradikācijas shēmas nozīmē atbilstoši Māstrihtas IV vadlīnijām. Pētījuma mērķis – salīdzīnāt ģimenes ārstu un speciālistu nozīmēto H. pylori eradikācijas shēmu efektivitāti un atbilstību vadlīnijām. Pētījumā piedalījās 550 pacienti, kuri bija ieradušies uz eradikācijas efektivitātes testa veikšanu. Ģimenes ārsti vadlīnijām atbilstošas eradikācijas shēmas bija nozīmējuši 85,8% gadījumu, bet gastroenterologi – 96,8% gadījumu. Ģimenes ārsti efektīvu H. pylori eradikācijas terapiju nozīmējuši 77,6% gadīju…

13C – urea elptestseradikācijagastroenterologsefektivitāteFarmācijaH. pylori
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The effect of substituted urea herbicides on the growth of excised tomato roots

1983

Summary The action of 23 herbictdal substituted ureas on the growth of excised tomato roots was studied in order to determine whether there is a link between the effects of these herbicides on oxidative phosphorylation and on the growth of non-photosynthetic tissues. Fourteen of these herbicides were inhibitory; chlortoluron and TBU were stimulatory but only in the light. Substituted ureas known to affect plant mitochondria inhibited root growth but to a lesser extent than some which had no action on mitochondria. No clear relationship was found between actions on mitochondria and on root growth. It is suggested that targets other than photosynthesis and oxidative phosphorylation exist for …

2. Zero hunger0106 biological sciencesChemistry04 agricultural and veterinary sciencesPlant Science01 natural sciencesMolecular biologySubstituted urea040103 agronomy & agriculture0401 agriculture forestry and fisheries[SDV.BV] Life Sciences [q-bio]/Vegetal BiologyAgronomy and Crop ScienceEcology Evolution Behavior and Systematics010606 plant biology & botany
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Plant removal disturbance and replant mitigation effects on the abundance and diversity of low-arctic soil biota

2014

Abstract Due to the dependence of soil organisms on plant derived carbon, disturbances in plant cover are thought to be detrimental for the persistence of soil biota. In this work, we studied the disturbance effects of plant removal and soil mixing and the mitigation effects of replanting on soil biota in a low-arctic meadow ecosystem. We set up altogether six replicate blocks, each including three randomized treatment plots, at two distinct fells at Kilpisjarvi, northern Finland. Vegetation was removed in two thirds of the plots: one third was then kept barren (the plant-removal treatment), while the other third was replanted with a local herb Solidago virgaurea. The remaining plots of int…

2. Zero hungerBiomass (ecology)EcologyFaunaSoil biologyfungiSoil ScienceGrowing seasonVegetation15. Life on landBiologybiology.organism_classificationAgricultural and Biological Sciences (miscellaneous)Solidago virgaureaAgronomyPlant coverta1181EcosystemApplied Soil Ecology
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NUOVI AGENTI TERAPEUTICI PER IL TRATTAMENTO DI PATOLOGIE EMATOLOGICHE

2019

La presente invenzione si riferisce al campo di nuove molecole tetracicliche, aventi un sistema tetraciclico, e loro impiego come medicamenti di patologie ematologiche in particolare per il trattamento della leucemia mieloide acuta (AML) in pazienti emizigoti FLT3/ITD resistenti alle terapie convenzionali.

2H-Imidazo [2'1':23][13]thiazolo[45-e]isoindol-8-yl)phenyl]ureas Acute myeloid leukemia (AML) Internal tandem duplication (ITD) FMS-like tyrosine kinase 3 (FLT3) FLT3/ITDSettore CHIM/08 - Chimica Farmaceutica
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NEW THERAPEUTIC AGENTS FOR THE TREATMENT OF HAEMATOLOGICAL PATHOLOGIES

2021

2H-Imidazo [2'1':23][13]thiazolo[45-e]isoindol-8-yl-phenylureas Acute myeloid leukemia (AML) Internal tandem duplication (ITD) FMS-like tyrosine kinase 3 (FLT3) FLT3/ITD
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Nanoparticles of a polyaspartamide-based brush copolymer for modified release of sorafenib: In vitro and in vivo evaluation.

2017

Abstract In this paper, we describe the preparation of polymeric nanoparticles (NPs) loaded with sorafenib for the treatment of hepatocellular carcinoma (HCC). A synthetic brush copolymer, named PHEA-BIB-ButMA (PBB), was synthesized by Atom Trasnfer Radical Polymerization (ATRP) starting from the α-poly( N -2-hydroxyethyl)- d , l -aspartamide (PHEA) and poly butyl methacrylate (ButMA). Empty and sorafenib loaded PBB NPs were, then, produced by using a dialysis method and showed spherical morphology, colloidal size, negative ζ potential and the ability to allow a sustained sorafenib release in physiological environment. Sorafenib loaded PBB NPs were tested in vitro on HCC cells in order to e…

3003MaleHepatocellular carcinomamedicine.medical_treatmentPharmaceutical Science02 engineering and technologyATRPPharmacology01 natural sciencesDrug Delivery SystemsCopolymerChemistryATRP; Hepatocellular carcinoma; Sorafenib; Tumor targeting; α-Poly(N-2-hydroxyethyl)-DL-aspartamide; 3003Liver NeoplasmsSorafenib021001 nanoscience & nanotechnologyDrug delivery0210 nano-technologymedicine.drugSorafenibNiacinamideCarcinoma HepatocellularCell SurvivalRadical polymerizationIntraperitoneal injectionL-aspartamideMice NudeAntineoplastic AgentsEnhanced permeability and retention effect010402 general chemistryPolymethacrylic AcidsIn vivoCell Line TumormedicineAnimalsHumansneoplasmsProtein Kinase InhibitorsPhenylurea Compoundstechnology industry and agriculturedigestive system diseasesIn vitro0104 chemical sciencesDrug LiberationTumor targetingDelayed-Action PreparationsBiophysicsα-Poly(N-2-hydroxyethyl)-DNanoparticlesα-Poly(N-2-hydroxyethyl)-DL-aspartamidePeptidesJournal of controlled release : official journal of the Controlled Release Society
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Global diversity in the TAS2R38 bitter taste receptor: revisiting a classic evolutionary PROPosal

2016

AbstractThe ability to taste phenylthiocarbamide (PTC) and 6-n-propylthiouracil (PROP) is a polymorphic trait mediated by the TAS2R38 bitter taste receptor gene. It has long been hypothesized that global genetic diversity at this locus evolved under pervasive pressures from balancing natural selection. However, recent high-resolution population genetic studies of TAS2Rs suggest that demographic events have played a critical role in the evolution of these genes. We here utilized the largest TAS2R38 database yet analyzed, consisting of 5,589 individuals from 105 populations, to examine natural selection, haplotype frequencies and linkage disequilibrium to estimate the effects of both selectio…

AFRICASELECTION0301 basic medicineLinkage disequilibriumPopulationLocus (genetics)Taste Genetics Evolutionary geneticsBiologyBalancing selectionLinkage DisequilibriumArticleReceptors G-Protein-CoupledEvolution Molecular03 medical and health sciences0302 clinical medicineDatabases GeneticGenetic variationLOCUSHumansPHENYLTHIOCARBAMIDESelection GeneticeducationPOPULATIONVEGETABLESGeneticsGenetic diversityeducation.field_of_studyHUMAN GENETIC DIVERSITY; SENSITIVITY; POPULATION; AFRICA; PTC; PHENYLTHIOCARBAMIDE; VEGETABLES; SELECTION; HUMANS; LOCUSNatural selectionMultidisciplinaryGenetic Variationphenylthiocarbamide (PTC) and 6-n-propylthiouracil (PROP)- TAS2R38 haplotypes-natural selectionPhenylthioureaCorrigendaSettore BIO/18 - GeneticaPTC030104 developmental biologyTAS2R38HaplotypesPropylthiouracilTasteHUMAN GENETIC DIVERSITYSENSITIVITY030217 neurology & neurosurgery
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A Simple System Based on a Thiourea-Modified Fluorescein for ω-Amino Acid Discrimination

2015

A thiourea-modified fluorescein derivative was synthesized by reaction of fluorescein isothiocyanate with 2-(2-aminoethoxy)ethan-1-ol. UV/Vis absorption and fluorescence emission spectroscopy studies demonstrated that this heteroditopic receptor was able to discriminate among linear aliphatic ω-amino acids with different chain lengths.

Absorption (pharmacology)chemistry.chemical_classificationOrganic ChemistrySupramolecular chemistryPhotochemistryFluorescenceAmino acidchemistry.chemical_compoundchemistryThioureaPhysical and Theoretical ChemistryFluoresceinFluorescein isothiocyanateDerivative (chemistry)Nuclear chemistryEuropean Journal of Organic Chemistry
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The cypsela (achene) of Echinacea purpurea as a diffusion unit of a community of microorganisms

2021

AbstractEchinacea purpurea is a plant cultivated worldwide for its pharmaceutical properties, mainly related to the stimulation of the immune system in the treatment of respiratory infections. The cypselas (fruits) of E. purpurea were examined in order to investigate the presence, localization and potential function(s) of endophytic microorganisms. Electron and confocal microscopy observations showed that three different components of microorganisms were associated to cypselas of E. purpurea: (i) one endocellular bacterial component in the cotyledons, enclosed within the host membrane; (ii) another more generic bacterial component adhering to the external side of the perianth; and (iii) a f…

AcheneHyphaEndophytic bacteriaSettore BIO/19 - Microbiologia GeneralePlant RootsApplied Microbiology and BiotechnologyEchinacea03 medical and health sciencesPaenibacillusEnvironmental BiotechnologyPerianthBotanyCypselaSoil MicrobiologyEchinacea purpurea030304 developmental biology0303 health sciencesBacteriabiologyPlant Extracts030306 microbiologyPantoeaFungifood and beveragesGeneral Medicinebiology.organism_classificationEchinaceaPlant LeavesGerminationAnatomyPerianthEchinacea Echinacea purpurea Endophytic bacteria Fungi Anatomy Cypsela PerianthBacteriaBiotechnology
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