Search results for "usa"
showing 10 items of 3178 documents
Evolutionary Changes after Translational Challenges Imposed by Horizontal Gene Transfer
2019
International audience; Genes acquired by horizontal gene transfer (HGT) may provide the recipient organism with potentially new functions, but proper expression level and integration of the transferred genes in the novel environment are not granted. Notably, transferred genes can differ from the receiving genome in codon usage preferences, leading to impaired translation and reduced functionality. Here, we characterize the genomic and proteomic changes undergone during experimental evolution of Escherichia coli after HGT of three synonymous versions, presenting very different codon usage preference, of an antibiotic resistance gene. The experimental evolution was conducted with and without…
Predicting common bottlenose dolphin habitat preference to dynamically adapt management measures from a Marine Spatial Planning perspective
2016
Abstract At the European Level, SACs (Special Areas of Conservation) are considered among the most reliable tools for increasing the efficiency of protective actions and to identify species vulnerability hotspots across spatial scales. Nevertheless, SACs may fail in their scope when design and management are not dynamically adapted to meet ecological principles. Knowledge of the spatial distribution of relevant key species, such as common bottlenose dolphin (Tursiops truncatus), is crucial in order to achieve the objective of the Habitat Directive (92/43/EEC), and is a fundamental step in the process of Marine Spatial Planning. From this perspective, new data and analysis are required to pr…
Cell interactions between a nonpathogenic Fusarium oxysporum strain and root tissues of Eucalyptus viminalis
2004
Nonpathogenic isolates of Fusarium oxysporum can be successful antagonists of pathogenic forms of the same fungal species that commonly attacks crop plants. The characteristics that distinguish nonpathogenic from pathogenic forms are not well understood. In this study, the mode of root colonization of Eucalyptus viminalis seedlings by a nonpathogenic F. oxysporum strain is described at the ultrastructural level. Root systems of E. viminalis plants were inoculated with nonpathogenic F. oxysporum strain Fo47 in an in vitro model system. Changes in the occurrence of nonesterified and methyl-esterified pectins in colonized E. viminalis roots were evaluated by in situ immunolabeling using two mo…
Predicting the invasion of the acoustic niche: Potential distribution and call transmission efficiency of a newly introduced frog in Cuba
2021
8 pages; International audience; Leptodactylus fragilis is a recently introduced frog in Cuba, where it may impact local populations of amphibians in different ways. Here, we combined two methods to predict the invasion of the acoustic niche of Cuban amphibians by L. fragilis. We first use species distribution models to predict the spread and establishment of L. fragilis in Cuba. We then performed sound propagation experiments to evaluate the potential invasion of the acoustic niche in predicted suitable areas for the presence of L. fragilis. This species could have a successful establishment, spreading mainly in open areas, where its advertisement calls propagate efficiently, with low atte…
The Strategic Reference Gene: an organismal theory of inclusive fitness
2019
How to define and use the concept of inclusive fitness is a contentious topic in evolutionary theory. Inclusive fitness can be used to calculate selection on a focal gene, but it is also applied to whole organisms. Individuals are then predicted to appear designed as if to maximise their inclusive fitness, provided that certain conditions are met (formally when interactions between individuals are 'additive'). Here we argue that applying the concept of inclusive fitness to organisms is justified under far broader conditions than previously shown, but only if it is appropriately defined. Specifically, we propose that organisms should maximise the sum of their offspring (including any accrued…
On Some Misconceptions Concerning Digital Banking and Alternative Delivery Channels
2016
A great deal of conceptual confusion surrounds the notions of digital banking and innovative alternative delivery channels that support banking and other financial transactions globally. The authors contend that the concepts of digital banking and associated delivery channels are ambiguous and restrictive; their usability has been undermined and their purpose and objective have, to a large extent, been misunderstood. Against this backdrop, the authors offer an inclusive definition of digital banking and delivery channels and provide logical explanations of these terms that can benefit scholars, the telecommunication sector, the banking industry, policy makers, and service providers (in term…
Teachers’ intention to use educational video games: The moderating role of gender and age
2018
Educational video games represent an educational change that challenges teachers and managers of Higher Education institutions in several ways including their attitude formation and behavioural intention. Using a Technology Acceptance Model (TAM) approach a research model is developed to predict teachers’ behavioural intention to use educational video games in their courses. The research model is tested via structural equation modelling (SEM) on a sample of 312 Higher Education teachers. Main results suggest that perceived usefulness influences in a direct and positive way teachers’ behavioural intention while perceived ease of use indirectly influences intention through perceived usefulnes…
Teaching clinical reasoning and decision-making skills to nursing students: Design, development, and usability evaluation of a serious game
2016
Background\ud \ud Serious games (SGs) are a type of simulation technology that may provide nursing students with the opportunity to practice their clinical reasoning and decision-making skills in a safe and authentic environment. Despite the growing number of SGs developed for healthcare professionals, few SGs are video based or address the domain of home health care.\ud \ud Aims\ud \ud This paper aims to describe the design, development, and usability evaluation of a video based SG for teaching clinical reasoning and decision-making skills to nursing students who care for patients with chronic obstructive pulmonary disease (COPD) in home healthcare settings.\ud \ud Methods\ud \ud A prototy…
Usability and acceptability assessment of an empathic virtual agent to prevent major depression
2016
In Human-Computer Interaction, the adaptation of the content and the way of how this content is communicated to the users in interactive sessions is a critical issue to promote the acceptability and usability of any computational system. We present a user-adapted interactive platform to identify and provide an early intervention for symptoms of depression and suicide. In particular, we describe the work performed to assess users' system acceptability and usability. An empathic Virtual Agent is the main interface with the user, and it has been designed to generate the appropriate dialogues and emotions during the interactions according to the detected user's specific needs. This personalizat…
Security Management in Health Care Information Systems — A Literature Review
2017
Health care information systems play an important role for communication across the organizational borders of health care services. The electronic health record represents the main entity in the management, exchange and storage of medical information. Health care organizations must adopt strategies for security and privacy risks associated with access to health care information systems, but on the other hand, the information needs to be accessible and readable for authorized health care professionals carrying out patient treatment. This paper presents a literature review on security management in health care information systems. The aim was to analyze descriptions and definitions of informa…