Search results for "uva"

showing 10 items of 2916 documents

Baicalin and berberine ultradeformable vesicles as potential adjuvant in vitiligo therapy.

2018

0.5-1% of the world's population is affected by vitiligo, a disease characterized by a gradual depigmentation of the skin. Baicalin and berberine are natural compounds with beneficial activities, such as antioxidant, anti-inflammatory and proliferative effects. These polyphenols could be useful for the treatment of vitiligo symptoms, and their efficacy can be improved by loading in suitable carriers. The aim of this work was to formulate and characterize baicalin or berberine loaded ultradeformable vesicles, and demonstrate their potential as adjuvants in the treatment of vitiligo. The vesicles were produced using a previously reported simple, scalable method. Their morphology, size distrib…

KeratinocytesBerberineSwineUltraviolet Raysmedicine.medical_treatmentDrug CompoundingSkin AbsorptionPopulationStatic ElectricityVitiligo02 engineering and technologyVitiligoPharmacology01 natural sciencesAntioxidantsPermeabilityMelaninchemistry.chemical_compoundColloid and Surface ChemistryBerberineDepigmentation0103 physical sciencesmedicineAnimalsHumansPhysical and Theoretical ChemistryeducationCell Line TransformedSkinFlavonoidsMelaninseducation.field_of_studyintegumentary system010304 chemical physicsChemistryMonophenol MonooxygenaseVesicleSurfaces and InterfacesGeneral Medicine021001 nanoscience & nanotechnologymedicine.diseaseLiposomesMelanocytesmedicine.symptom0210 nano-technologyBaicalinAdjuvantSunscreening AgentsBiotechnologyColloids and surfaces. B, Biointerfaces
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An integrated humoral and cellular response is elicited in pancreatic cancer by alpha-enolase, a novel pancreatic ductal adenocarcinoma-associated an…

2009

Pancreatic ductal adenocarcinoma (PDAC) is a fatal disease with a very poor 5-year survival rate. alpha-Enolase is a glycolytic enzyme that also acts as a surface plasminogen receptor. We find that it is overexpressed in PDAC and present on the cell surface of PDAC cell lines. The clinical correlation of its expression with tumor status has been reported for lung and hepatocellular carcinoma. We have previously demonstrated that sera from PDAC patients contain IgG autoantibodies to alpha-enolase. The present work was intended to assess the ability of alpha-enolase to induce antigen-specific T cell responses. We show that alpha-enolase-pulsed dendritic cells (DC) specifically stimulate healt…

KeratinocytesCancer ResearchPancreatic diseaseendocrine system diseasesalpha-enolaseAntibodies NeoplasmAlpha-enolaseT-LymphocytesMiceSkinImmunity Cellularhuman; pancreatic ductal adenocarcinoma; alpha enolase; tumor antigen; B cell response; T cell responsebiologyalpha enolasehuman; pancreatic ductal adenocarcinoma; alpha-enolase; tumor antigen; B cell response; T cell responseImmunohistochemistryTumor antigenUp-RegulationGene Expression Regulation Neoplasticmedicine.anatomical_structureOncologyAntibodyCarcinoma Pancreatic DuctalB cell responseT cellBlotting Westernpancreatic ductal adenocarcinomaGene Expression Regulation EnzymologicInterferon-gammaImmune systemAntigenAntigens NeoplasmCell Line TumorPancreatic cancermedicineAnimalsHumanshumanPancreasCell ProliferationDendritic Cellsmedicine.diseaseT cell responsepancreatic ductal adenocarcinoma; alpha-enolase; tumor antigen.digestive system diseasesPancreatic NeoplasmsImmunoglobulin GPhosphopyruvate HydrataseAntibody FormationImmunologybiology.proteintumor antigenT-Lymphocytes Cytotoxic
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Imiquimod-Induced Psoriasis in Mice Depends on the IL-17 Signaling of Keratinocytes

2018

The pathology of psoriasis strongly depends on IL-17A. Monoclonal antibodies blocking either the cytokine or its receptor are among the most efficient treatments for psoriatic patients. Keratinocytes can be activated upon exposure to IL-17A and tumor necrosis factor-α and secrete secondary cytokines and chemokines in the inflamed skin. In psoriasis and its imiquimod-induced mouse model, a strong skin infiltration of neutrophils and inflammatory monocytes can be observed. However, to date, it is not clear how exactly those cellular populations are attracted to the skin and how they contribute to the pathogenesis of the disease. To define the crucial cell type responding to IL-17 and initiati…

KeratinocytesMale0301 basic medicineCell typeChemokinemedicine.medical_treatmentImiquimodDermatologyReal-Time Polymerase Chain ReactionBiochemistryMiceRandom Allocation03 medical and health sciences0302 clinical medicineAdjuvants ImmunologicPsoriasismedicineAnimalsPsoriasisMolecular BiologyCells CulturedImiquimodbiologyTumor Necrosis Factor-alphabusiness.industryBiopsy NeedleInterleukin-17Cell BiologyFlow Cytometrymedicine.diseaseImmunohistochemistryMice Inbred C57BLDisease Models Animal030104 developmental biologyCytokinemedicine.anatomical_structure030220 oncology & carcinogenesisImmunologybiology.proteinCytokinesFemaleTumor necrosis factor alphaInterleukin 17KeratinocytebusinessSignal Transductionmedicine.drugJournal of Investigative Dermatology
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Entwicklung der Hornhautdicke während der UV-Vernetzungstherapie unter Anwendung verschiedener Kompositionen von Riboflavin-Augentropfen

2011

Background During the UVA-cross-linking treatment in keratoconus patients, the UVA rays are partially absorbed in the stroma of the riboflavin-loaded cornea. This effect protects the corneal endothelium from UVA irradiation damage. The intensity of UVA light reaching the endothelium is inversely correlated with corneal thickness. The common composition of riboflavin eye drops may lead to a marked reduction in corneal thickness increasing the risk of endothelial damage. Patients and methods In a retrospective analysis of 23 UVA-cross-linking procedures on 23 patients we collected data about the pre-, intra- and postoperative corneal thickness (measured with ultrasound). Among these patients …

KeratoconusCorneal endotheliummedicine.medical_specialtygenetic structuresbusiness.industryUltrasoundRiboflavinmedicine.diseaseeye diseasesIntensity (physics)SurgeryOphthalmologyDose–response relationshipmedicine.anatomical_structureCorneaOphthalmologymedicineUva irradiationsense organsbusinessKlinische Monatsblätter für Augenheilkunde
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MR2865796 Riecan, Beloslav; Tkacik, Štefan A note on the Kluvánek integral. Tatra Mt. Math. Publ. 49 (2011), 59--65

2011

Kluvanek integralSettore MAT/05 - Analisi Matematica
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Impiego enologico di un ceppo di Kluyveromyces marxianus isolato a Linosa

2014

Kluyveromyces marxianu Linosa uva da vinoSettore AGR/15 - Scienze E Tecnologie Alimentari
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Koulukiusaaminen, sosiaaliset suhteet, minäkäsitys ja fyysiset ominaisuudet peruskoululaisilla

2006

Kohtaamisia koululiikunnassa -tutkimuskoulukiusaaminenkoululiikuntaminäkuvaperuskoulun yläasteitsetuntemusliikuntaharrastusruumiinkuvasosiaaliset suhteet
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BVP ir skolinimo elgsena : empiriniai Baltijos šalių ekonomikos požymiai

2021

Darnus ekonominis vystymasis remiasi stabilia ir palankia verslo aplinka, kuri skatina organizacijų konkurencingumą. Komerciniai bankai palengvina kapitalo judėjimą iš mažiau efektyvių ekonomikos sektorių į labiau konkurencingas ekonomikos šakas. Šio tyrimo tikslas – išanalizuoti Baltijos šalių BVP dinamiką 2005-2010 metais ir patikrinti BVP koreliavimą su vietinių komercinių bankų išduotų paskolų verslui skaičiumi. Tyrimo rezultatai parodė, kad yra požymių, jog egzistuoja abipusė priklausomybė tarp BVP veiksnių ir išduotų paskolų, tai savo ruožtu sudaro pagrindą formuoti pasiūlymus, kaip gaivinti Baltijos šalių ekonomiką. Šešiose pramonės šakose atliktas Granger BVP ir skolinimo priežastin…

Kreditas. Paskolos / CreditEconomic sectorGDPGranger causality testBusiness environmentLietuva (Lithuania)EconomyGranger causalityBVPEconomicsGeneral Earth and Planetary SciencesCapital flowsGranger priežastingumo testasEmpirical evidenceGeneral Environmental ScienceRegional Formation and Development Studies
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Kriminālprocesa obligātums un lietderīgums kā kriminālās justīcijas sistēmas pamatprincips.

2023

Monogrāfija sagatavota Eiropas Savienības fonda 2014.–2020. gada plānošanas perioda Darbības programmas “Izaugsme un nodarbinātība” prioritārā virziena “Mazo un vidējo komersantu konkurētspēja” ieguldījuma prioritātes “Investīcijas institucionālajās spējās un efektīvā valsts pārvaldē un publiskajos pakalpojumos valsts, reģionālajā un vietējā līmenī, lai panāktu reformas, labāku regulējumu un labu pārvaldību” Eiropas Sociālā fonda projekta “Justīcija attīstībai” (Nr. 3.4.1.0/16/I/001) ietvaros (projekta vadītāja: Kristīne Strada-Rozenberga), veicot pētījumu “Kriminālprocesa obligātuma principa ietekme uz kriminālprocesa efektivitāti”.

Kriminālprocesa obligātumsAtteikšanās no kriminālprocesaObligātums un lietderība kriminālprocesā - Igaunija Latvija Lietuvakriminālprocess - terminiKriminālprocesa lietderība - teorija prakse:LAW/JURISPRUDENCE::Procedural law::Criminal procedure [Research Subject Categories]Obligātums un liederība kriminālprocesā - Čehija Slovākija Nīderlande Šveice Vācija ZviedrijaLatvijas tiesību piemērošana praksē - kriminālprocess
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Latvijas Vēstures Institūta Žurnāls. 2018, Nr. 1 (106)

2018

LU Akadēmiskās attīstības projekts "Zinātniskā periodiskā izdevuma "Latvijas Vēstures Institūta žurnāls" sagatavošana un izdošana 2018. gadā"

Krustvecāku izvēle Rīgas pārcēlāju amata locekļu bērniemLietuvas sūtniecība Latvijā:HUMANITIES and RELIGION::History and philosophy subjects::Archaeology subjects [Research Subject Categories]:HUMANITIES and RELIGION::History and philosophy subjects::History subjects [Research Subject Categories]RecenzijasZinātnes dzīvePareizticība ZiemeļkurzemēKāstuve deglis vai ogļu trauks
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