Search results for "vaccino"
showing 10 items of 14 documents
Interim 2017/18 influenza seasonal vaccine effectiveness: combined results from five European studies
2018
Between September 2017 and February 2018, influenza A(H1N1)pdm09, A(H3N2) and B viruses (mainly B/Yamagata, not included in 2017/18 trivalent vaccines) co-circulated in Europe. Interim results from five European studies indicate that, in all age groups, 2017/18 influenza vaccine effectiveness was 25 to 52% against any influenza, 55 to 68% against influenza A(H1N1)pdm09, -42 to 7% against influenza A(H3N2) and 36 to 54% against influenza B. 2017/18 influenza vaccine should be promoted where influenza still circulates. Funding: The five studies have received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No 634446 to conduct the study in…
Type-IIA secreted phospholipase A2 is an endogenous antibiotic-like protein of the host.
2010
International audience; Type-IIA secreted phospholipase A(2) (sPLA(2)-IIA) has been proposed to play a role in the development of inflammatory diseases. It has been shown to release arachidonic acid, the precursor of proinflammatory eicosanoids, to hydrolyze phospholipids of pulmonary surfactant, and to bind to specific receptors located on cell surface membranes. However, the most established biological role of sPLA(2)-IIA is related to its potent bactericidal property in particular toward Gram-positive bacteria. This enzyme is present in animal and human biological fluids at concentrations sufficient to kill bacteria. Human recombinant sPLA(2)-IIA is able to kill Gram-positive bacteria at…
Comparative study of a whole-cell pertussis vaccine and a recombinant acellular pertussis vaccine.
1994
The safety and immunogenicity of an acellular pertussis vaccine containing the genetically detoxified pertussis toxin PT-9K/129C, filamentous hemagglutinin, and pertactin, together with diphtheria and tetanus toxoids, were compared with those of a whole-cell pertussis component-diphtheria-tetanus vaccine. Four hundred eighty infants were enrolled into this prospective, multicenter, double-blind study. Each infant was randomly given three doses of one of the two vaccines at 2, 4, and 6 months of age. Both local and systemic adverse reactions, reported within 48 hours and 7 days of each injection, were less frequent after the acellular vaccine than after the whole-cell vaccine. The enzyme-lin…
La vaccinazione antinfluenzale come Strumento di Sanità pubblica e di prevenzione. Esperienza dell'Azienda Ospedaliero Universitaria Policlinico (AOU…
2009
Introduzione Le Linee guida per la prevenzione e controllo dell'influenza, emanano Ogni anno dal Ministero della Salute, raccomandano la vaccinazione per tutti Coloro Che svolgono Funzioni lavorative di primario interesse collettivo. Il personale sanitario rappresenta, un tal Riguardo, un obiettivo strategico della campagna da vaccino antinfluenzale SIA per la possibile trasmissione dell'influenza aviaria Pazienti SIA Perchè l'eventuale assenteismo Potrebbe inficiare la qualità e la Capacità dell'Assistenza erogata. La trasmissione dell'influenza ad un Paziente è sicuramente un importante Rischio nosocomiale in Quanto l'Infezione virale PUÒ portare ad un aggravamento dello stato di salute d…
Toward ‘Vaccine Internationalism’: The Need for an Equitable and Coordinated Global Vaccination Approach to Effectively Combat COVID-19
2021
International audience
LA PREVENZIONE ED IL TRATTAMENTO DELLE PATOLOGIE HPV-CORRELATE: FOLLOW-UP E PERFORMANCE RIPRODUTTIVA
2007
Relationship between HPV-infection and reproductive performance includes patients who during trial become pregnant. Main chapter indeed represents genital lesions treatments sequelae. Clinical phase 3 studies showed that spontaneous abortion rate in both groups (Gardasil and placebo respectively) was comparable (33% vs 31.6%). Moreover, there were 25 cases of congenital abnormalities among newborns and live foetuses, and congenital abnormalities global rate was similar than normal population. Therefore, there is no evidence that Gardasil adversely influences fertility, pregnancy and neonatal outcome. Cold-cut conization, laser-conization, laser-ablation, LEEP or LLETZ are conservative techn…
Corsa al vaccino
2001
VACCINO QUADRIVALENTE ANTI-HPV NELLA PREVENZIONE DELLA PATOLOGIA VAGINALE, VULVARE E DEI CONDILOMI ANOGENITALI
2008
Stato vaccinale e immunitario contro le malattie prevenibili da vaccino in un campione di operatori sanitari del Policlinico Universitario di Palermo
2019
Introduzione La vaccinazione degli operatori sanitari (OS) riduce il rischio delle infezioni professionali, previene la trasmissione nosocomiale e garantisce la continuità delle cure sanitarie durante le epidemie di malattie vaccinoprevenibili. Nonostante le raccomandazioni del Piano Nazionale della Prevenzione Vaccinale 2017-2019, la copertura vaccinale degli OS in Italia risulta molto bassa. Scopo dello studio è valutare lo stato vaccinale e immunitario degli OS del Policlinico Universitario di Palermo. Materiali e metodi Un questionario anonimo è stato somministrato online tra Settembre e Dicembre 2018 agli OS del Policlinico Universitario di Palermo. Il questionario era suddiviso nelle …
Initiation of adaptive immune responses by transcutaneous immunization.
2007
The development of new, effective, easy-to-use and lower-cost vaccination approaches for the combat against malignant and infectious diseases is a pre-eminent need: cancer is a leading cause of morbidity in the Western World; there are numerous pathogenic diseases for which we still have no protective or therapeutic cure; and the financial limitations of developing countries to fight these diseases. In this mini-review we focus on transcutaneous immunization (TCI), a relatively new route for antigen delivery. TCI protocols appear to be particularly promising by gaining access to skin resident APC, which are highly efficient for the initiation of humoral and/or cellular immune responses. Con…