Search results for "vacuole."

showing 10 items of 93 documents

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

2016

Seuls les 100 premiers auteurs dont les auteurs INRA ont été entrés dans la notice. La liste complète des auteurs et de leurs affiliations est accessible sur la publication.; International audience; In 2008 we published the first set of guidelines for standardizing research in autophagy. Since then, research on this topic has continued to accelerate, and many new scientists have entered the field. Our knowledge base and relevant new technologies have also been expanding. Accordingly, it is important to update these guidelines for monitoring autophagy in different organisms. Various reviews have described the range of assays that have been used for this purpose. Nevertheless, there continues…

[SDV]Life Sciences [q-bio]autophagosomeReview Articleddc:616.07stressstreLC3MESH: AnimalsSettore MED/49 - Scienze Tecniche Dietetiche ApplicateSettore BIO/06 - Anatomia Comparata E Citologiachaperone-mediated autophagyComputingMilieux_MISCELLANEOUSSettore BIO/11Pharmacology. TherapySettore BIO/13standards [Biological Assay]autolysosomeMESH: Autophagy*/physiologylysosomemethods [Biological Assay]Biological AssaySettore BIO/17 - ISTOLOGIAErratumHumanBiochemistry & Molecular BiologySettore BIO/06physiology [Autophagy]Chaperonemediated autophagy[SDV.BC]Life Sciences [q-bio]/Cellular BiologyNOautophagy guidelines molecular biology ultrastructureautolysosome; autophagosome; chaperone-mediated autophagy; flux; LC3; lysosome; macroautophagy; phagophore; stress; vacuoleMESH: Biological Assay/methodsMESH: Computer Simulationddc:570Autolysosome Autophagosome Chaperonemediated autophagy Flux LC3 Lysosome Macroautophagy Phagophore Stress VacuoleAutophagyAnimalsHumansComputer SimulationSettore BIO/10ddc:612BiologyphagophoreMESH: HumansvacuoleAnimalLC3; autolysosome; autophagosome; chaperone-mediated autophagy; flux; lysosome; macroautophagy; phagophore; stress; vacuole; Animals; Biological Assay; Computer Simulation; Humans; Autophagy0601 Biochemistry And Cell BiologyfluxmacroautophagyMESH: Biological Assay/standards*Human medicineLC3; autolysosome; autophagosome; chaperone-mediated autophagy; flux; lysosome; macroautophagy; phagophore; stress; vacuole
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Autophagy

2012

Klionsky, Daniel J. et al.

autophagy assays[SDV]Life Sciences [q-bio]AutolysosomeAutophagosome maturationautophagosomeBioinformaticsstressChaperone-mediated autophagyModelsLC3MESH: Animalsguidelinesautolysosome autophagosome flux LC3 lysosome phagophore stress vacuoleSettore BIO/06 - Anatomia Comparata E CitologiaComputingMilieux_MISCELLANEOUSSettore BIO/17Autophagy databaseautolysosome3. Good healthddc:540lysosomeEnergy and redox metabolism Mitochondrial medicine [NCMLS 4]methods [Biological Assay]Biological AssaySettore BIO/17 - ISTOLOGIANeuroniMAP1LC3BHumanautophagygenetics [Autophagy]AutofagiaMESH: Autophagy*/genetics[SDV.BC]Life Sciences [q-bio]/Cellular BiologyAutofagia; Neuroni; istologiaBiologyModels BiologicalLC3; autolysosome; autophagosome; flux; lysosome; phagophore; stress; vacuoleddc:570AutophagyAnimalsHumansAutophagy-Related Protein 7[SDV.BC] Life Sciences [q-bio]/Cellular BiologyBiological Assay/methodsMolecular BiologyBiologyAutophagy; guidelines; autophagy assaysistologiaphagophoreMESH: HumansAnimals; Biological Assay; Humans; Models Biological; AutophagyvacuoleAnimal[ SDV.BC ] Life Sciences [q-bio]/Cellular BiologyMESH: Models BiologicalPathogenesis and modulation of inflammation Infection and autoimmunity [N4i 1]Cell BiologyBiologicalAutophagy/geneticsfluxAutophagosome membraneAutophagy Protein 5Human medicineMESH: Biological Assay/methods*Neuroscienceautolysosome; autophagosome; flux; LC3; lysosome; phagophore; stress; vacuoleAutophagy
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Cellular and Subcellular Localization of Peroxidase Isoenzymes in Plants and Cell Suspension Cultures from Lupinus polyphyllus

1989

Abstract , leaf protoplasts and cell suspension cultures of Lupinus polyphyllus and isolated vacuoles were studied for cellular and subcellular localization of peroxidase isoenzymes. Isoelectric focusing revealed 16 peroxidase isoenzymes. The basic peroxidase isoenzymes are predominantly localized in the vacuole and, to a minor degree, unbound in the intercellular space. The acidic isoenzymes are cell wall-bound in plants and not detectable in suspension-cultured cells. Large amounts (up to 11.0 U/ml) of a single basic isoenzyme are detectable in the spent medium of cell suspension cultures.

biologyChemistryLupinus polyphyllusIsoelectric focusingCellVacuoleProtoplastSubcellular localizationbiology.organism_classificationMolecular biologyIsozymeGeneral Biochemistry Genetics and Molecular Biologymedicine.anatomical_structureBiochemistrybiology.proteinmedicinePeroxidaseZeitschrift für Naturforschung C
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Follicle Cells of Styela plicata Eggs (Ascidiacea)

2001

Styela plicata eggs are surrounded by large follicle cells that at LM appear as highly vacuolated and columnar in shape; at the apical end of each cell lies a very large and clear vacuole, half of which extends inward. Electron microscope observations show a Single layer of largely spaced box-like follicle cells; the close cell-cell contact at their base is realized by interdigitations. The cell surface shows a peculiar structure, more developed in the latero-basal regions, consisting of a complex of membrane extensions, i.e. microvilli, filopodia and lamellipodia. Filopodia irradiate in all directions towards the adjacent cells and the outermost vitelline coat, thus creating a complex netw…

biologyChemistryVacuoleApical membranebiology.organism_classificationlaw.inventionCell biologyFollicleStyela plicatalawSecretionElectron microscopeLamellipodiumFilopodia
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The Follicle Cells of Styela Plicata (Ascidiacea, Tunicata): A Sem Study

2000

The morphological aspect of the follicle cells of Styela plicata eggs is described by means of scanning electron microscope investigations. The follicular layer is made of spaced, cylindrical box-like cells which are arranged hexagonally. They adhere to the egg through a complex network of membrane extensions making an overall thin layer on the vitelline coat. The walls of the follicle cells are plentifully provided with microvilli, filopodia and lamellipodia, which allow a connection among the cells. At their apical end lies a large vacuole containing a granule, probably involved in secretion. At insemination the majority of spermatozoa is distributed on the apical membrane of the follicle…

biologyGranule (cell biology)VacuoleAnatomyApical membranebiology.organism_classificationCell biologyFollicleStyela plicataembryonic structuresAnimal Science and ZoologyLamellipodiumFilopodiaAscidiaceaZoological Science
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The Formation of The Plant Vacuolar System

1999

The plant vacuole is a multifunctional subcellular compartment. In general, the vacuolar system is constituted of a single or few vacuoles. About 80% of the volume of mature plant cells is occupied by vacuoles. These organelles are limited by a single membrane, the tonoplast. According to the cell type and to particular functions, the vacuolar content can vary from a homogeneous consistency to a heterogeneous matrix containing crystalloid structures (Boiler, Wiemken, 1986; Marty et al., 1980). From the biotechnological point of view, the endomembrane system of plants, particularly the ER and vacuoles, can be envisioned as the ultimate environment for stable protein accumulation. Several rep…

chemistry.chemical_classificationchemistryfungiOrganelleProtein storage vacuolefood and beveragesStorage proteinEndomembrane systemVacuoleCompartment (chemistry)Matrix (biology)Plant cellCell biology
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A barley (Hordeum vulgare L.) LEA3 protein, HVA1, is abundant in protein storage vacuoles

1996

The HVA1 protein belongs to the LEA3 group, which is expressed during the late stage of seed maturation. It is also induced by exogenous abscisic acid (ABA) and a variety of environmental stresses in germinating barley (Hordeum vulgare L.). In the present work, the potential role of HVA1 was investigated by studying its tissue distribution and subcellular localization in mature and stressed seeds by immuno-microscopic methods. In the mature seed, HVA1 protein was detected in all tissues except the non-living starchy endosperm. During germination the amount of HVA1 protein decreased but did not totally disappear. Incubation with 100 μM ABA, cold treatment or drought stress dramatically incre…

chemistry.chemical_classificationfood and beveragesPlant ScienceVacuoleBiologyScutellumEndospermchemistry.chemical_compoundVacuolar pathwaychemistryBiochemistryAleuroneGeneticsStorage proteinHordeum vulgareAbscisic acidPlanta
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B and T lymphocytes are affected in lysosomal disorders--an immunoelectron microscopic study.

1991

Circulating lymphocytes of four patients with mucopolysaccharidoses II and IIIA, four patients with juvenile neuronal ceroid-lipofuscinosis, one patient each with glycogenosis type II, infantile neuronal ceroid-lipofuscinosis, and Gaucher disease were classified by immunoelectron microscopy as B or T lymphocytes. Disease-specific lysosomal inclusions as well as non-specific lysosomal organelles, especially Gall bodies were identified in B and T lymphocytes. These non-quantitative studies indicate that both B and T lymphocytes participate in the lysosomal storage process.

congenital hereditary and neonatal diseases and abnormalitiesPathologymedicine.medical_specialtyHistologyImmunoelectron microscopyMucopolysaccharidosisT-LymphocytesCentral nervous systemVacuoleBiologyPathology and Forensic MedicinePhysiology (medical)OrganellemedicineLysosomal storage diseaseHumansMicroscopy ImmunoelectronB-Lymphocytesnutritional and metabolic diseasesT lymphocytemedicine.diseasemedicine.anatomical_structureNeurologyNeuronal ceroid lipofuscinosisNeurology (clinical)Metabolism Inborn ErrorsNeuropathology and applied neurobiology
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Allosteric regulation by Mg2+ of the vacuolar H(+)-PPase from Acer pseudoplatanus cells. Ca2+/Mg2+ interactions.

1996

The tonoplast H(+)-PPase was previously characterized in Acer pseudoplatanus cells (Pugin et al (1991) Plant Sci 73, 23-34; Fraichard et al (1993) Plant Physiol Biochem 31, 349-359). Tonoplast vesicles were obtained from vacuoles isolated from protoplasts of A pseudoplatanus suspension cultures and used to study kinetic effects of Mg2+ and Ca2+ on PPi hydrolysis. The concentrations of ionic species (free Mg2+, free PPi, and MgPPi complexes) were calculated with apparent dissociation constants of 55.3 microM for MgPPi and 59.6 microM for CaPPi. Our results indicated that the substrate of the tonoplast PPase was a MgPPi complex and that free Mg2+ was essential for PPi hydrolysis. With fixed f…

inorganic chemicals0106 biological sciencesTrisAllosteric regulation01 natural sciencesBiochemistryTrees03 medical and health sciencesEnzyme activatorchemistry.chemical_compoundOrganophosphorus CompoundsAllosteric Regulation[SDV.BBM] Life Sciences [q-bio]/Biochemistry Molecular Biology[SDV.BBM]Life Sciences [q-bio]/Biochemistry Molecular BiologyMagnesiumBinding sitePyrophosphatasesComputingMilieux_MISCELLANEOUSCells Cultured030304 developmental biologychemistry.chemical_classification0303 health sciencesInorganic pyrophosphataseERABLE FAUX PLATANEGeneral MedicineDissociation constantEnzyme ActivationInorganic PyrophosphataseKineticsEnzymechemistryBiochemistryVacuolesCalciumUncompetitive inhibitor010606 plant biology & botanyBiochimie
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Defective copper transport in the copt5 mutant affects cadmium tolerance.

2014

Cadmium toxicity interferes with essential metal homeostasis, which is a problem for both plant nutrition and the consumption of healthy food by humans. Copper uptake is performed by the members of the Arabidopsis high affinity copper transporter (COPT) family. One of the members, COPT5, is involved in copper recycling from the vacuole toward the cytosolic compartment. We show herein that copt5 mutants are more sensitive to cadmium stress than wild-type plants, as indicated by reduced growth. Exacerbated cadmium toxicity in copt5 mutants is due specifically to altered copper traffic through the COPT5 transporter. Three different processes which have been shown to affect cadmium tolerance ar…

inorganic chemicalsPhysiologyIronMutantArabidopsischemistry.chemical_elementPlant DevelopmentPlant ScienceVacuolemedicine.disease_causeModels BiologicalPlant RootsGene Expression Regulation PlantStress PhysiologicalEtiolationmedicineArabidopsis thalianaSLC31 ProteinsCation Transport ProteinsCadmiumbiologyArabidopsis ProteinsBiological TransportCell BiologyGeneral MedicineEthylenesmedicine.diseasebiology.organism_classificationCopperAdaptation PhysiologicalHypocotylddc:Cell biologyOxidative StresschemistrySeedlingsToxicityMutationLipid PeroxidationCopper deficiencyOxidative stressBiomarkersCopperCadmiumPlantcell physiology
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